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Scandinavian Journal of Rheumatology Volume 49, 2020 - Issue 1
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Letters

New onset of psoriasis induced by secukinumab in a patient with ankylosing spondylitis: a case report

D CurradoUnit of Allergology, Immunology, Rheumatology, Department of Medicine, Campus Bio-Medico University of Rome, Rome, ItalyCorrespondence[email protected]
,
DPE MargiottaUnit of Allergology, Immunology, Rheumatology, Department of Medicine, Campus Bio-Medico University of Rome, Rome, Italy
,
C ConfortiDermatology Clinic, Maggiore Hospital, University of Trieste, Trieste, Italy
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R CoppolaUnit of Plastic and Reconstructive Surgery, Sapienza University, Rome, Italy;Unit of Plastic and Reconstructive Surgery, Department of Medicine, Campus Bio-Medico University of Rome, Rome, Italy
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V PanasitiUnit of Plastic and Reconstructive Surgery, Department of Medicine, Campus Bio-Medico University of Rome, Rome, Italy
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A AfeltraUnit of Allergology, Immunology, Rheumatology, Department of Medicine, Campus Bio-Medico University of Rome, Rome, Italy
&
L NavariniUnit of Allergology, Immunology, Rheumatology, Department of Medicine, Campus Bio-Medico University of Rome, Rome, Italy
 show all
Pages 75-76 | Accepted 09 Mar 2019, Published online: 02 Jul 2019

References

  • Braun J, Sieper J. Ankylosing spondylitis. Lancet 2007;369:1379–90.
  • Braun J, Baraliakos X, Deodhar A, Baeten D, Sieper J, Emery P, et al. Effect of secukinumab on clinical and radiographic outcomes in ankylosing spondylitis: 2-year results from the randomised phase III MEASURE 1 study. Ann Rheum Dis 2017;76:1070–7.
  • Baraliakos X, Kivitz AJ, Deodhar AA, Braun J, Wei JC, Delicha EM, et al. Long-term effects of interleukin-17A inhibition with secukinumab in active ankylosing spondylitis: 3-year efficacy and safety results from an extension of the phase 3 MEASURE 1 trial. Clin Exp Rheumatol 2018;36:50–5.
  • Baeten D, Sieper J, Braun J, Baraliakos X, Dougados M, Emery P, et al. Secukinumab, an Interleukin-17A inhibitor, in ankylosing spondylitis. N Engl J Med 2015;373:2534–48.
  • Abrouk M, Gandy J, Nakamura M, Lee K, Brodsky M, Singh R, et al. Secukinumab in the treatment of psoriasis and psoriatic arthritis: a review of the literature. Skin Therapy Lett 2017;22:1–6.
  • Bae JM, Kwon HS, Kim GM, Park KS, Kim KJ. Paradoxical psoriasis following anti-TNF therapy in ankylosing spondylitis: a population-based cohort study. J Allergy Clin Immunol 2018;142:1001–3.e2.
  • Noell C, McQuade B, Gottlieb A, Rosmarin D. Anti IL-17 flared psoriasis in a patient on secukinumab. Dermatol Ther 2017;30:e12505.
  • Sladden MJ, Sladden CS, Gulliver WPF. Secukinumab-induced psoriasiform eruption. JAMA Dermatol 2017;153:1194–5.
  • Dogra S, Bishnoi A, Narang T, Handa S. Secukinumab-induced paradoxical pustular psoriasis. Clin Exp Dermatol 2019;44:72–3.
  • Hoshina D, Haga N, Furuya K, Sakai M. Paradoxical localized exacerbation of psoriatic eruptions triggered by secukinumab. Clin Exp Dermatol 2018;43:718–19.

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