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Articles

Increased risk of osteoporotic fractures in Swedish patients with rheumatoid arthritis despite early treatment with potent disease-modifying anti-rheumatic drugs: a prospective general population-matched cohort study

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Pages 431-438 | Accepted 24 Apr 2019, Published online: 19 Jul 2019

References

  • Vis M, Güler-Yüksel M, Lems WF. Can bone loss in rheumatoid arthritis be prevented? Osteoporos Int 2013;24:2541–53.
  • Hooyman JR, Melton LJ, Nelson AM, O’Fallon WM, Riggs BL. Fractures after rheumatoid arthritis. A population-based study. Arthritis Rheum 1984;27:1353–61.
  • Michel BA, Bloch DA, Wolfe F, Fries JF. Fractures in rheumatoid arthritis: an evaluation of associated risk factors. J Rheumatol 1993;20:1666–9.
  • Haugeberg G, Uhlig T, Falch JA, Halse JI, Kvien TK. Bone mineral density and frequency of osteoporosis in female patients with rheumatoid arthritis – results from 394 patients in the Oslo County Rheumatoid Arthritis Register. Arthritis Rheum 2000;43:522–30.
  • Haugeberg G, Uhlig T, Falch JA, Halse JI, Kvien TK. Reduced bone mineral density in male rheumatoid arthritis patients – frequencies and associations with demographic and disease variables in ninety-four patients in the Oslo county rheumatoid register. Arthritis Rheum 2000;43:2776–84.
  • Sinigaglia L, Nervetti A, Mela Q, Bianchi G, Del Puente A, Di Munno O, et al. A multicenter cross sectional study on bone mineral density in rheumatoid arthritis. J Rheumatol 2000;27:2582–9.
  • Huusko TM, Korpela M, Karppi P, Avikainen V, Kautiainen H, Sulkava R. Threefold increased risk of hip fractures with rheumatoid arthritis in Central Finland. Ann Rheum Dis 2001;60:521–2.
  • Kim SY, Schneeweiss S, Liu J, Daniel GW, Chang CL, Garneau K, et al. Risk of osteoporotic fracture in a large population-based cohort of patients with rheumatoid arthritis. Arthritis Res Ther 2010;12:R154.
  • Brennan SL, Toomey L, Kotowicz MA, Henry MJ, Griffiths H, Pasco JA. Rheumatoid arthritis and incident fracture in women: a case–control study. BMC Musculoskelet Disord 2014;15:13.
  • Lin YC, Li YH, Chang CH, Hu CC, Chen DW, Hsieh PH, et al. Rheumatoid arthritis patients with hip fracture: a nationwide study. Osteoporos Int 2015;26:811–17.
  • Van Staa TP, Geusens P, Bijlsma JWJ, Leufkens HGM, Cooper C. Clinical assessment of the long-term risk of fractures in patients with rheumatoid arthritis. Arthritis Rheum 2006;54:3104–12.
  • Kamen DL, Alele JD. Skeletal manifestations of systemic autoimmune diseases. Curr Opin Endocrinol Diabetes Obes 2010;17:540–5.
  • Caetano-Lopes J, Canhao H, Fonseca JE. Osteoimmunology – the hidden immune regulation of bone. Autoimmun Rev 2009;8:250–5.
  • Iseme RA, Mcevoy M, Kelly B, Agnew L, Walker FR, Attia J. Is osteoporosis an autoimmune mediated disorder? Bone Rep 2017;7:121–31.
  • Hofbauer LC, Hamann C, Ebeling PR. Approach to the patient with secondary osteoporosis. Eur J Endocrinol 2010;162:1009–20.
  • Kanis JA, Johnell O, Oden A, Johansson H, Mc Closkey E. FRAX and the assessment of fracture probability in men and women from the UK. Osteoporos Int 2008;19:385–97.
  • Lee CK, Lee EY, Chung SM, Mun SH, Yoo B, Moon HB. Effects of disease-modifying antirheumatic drugs and anti-inflammatory cytokines on human osteoclastogenesis through interaction with receptor activator of nuclear factor κB, osteoprotegrin, and receptor activator of nuclear factor κB ligand. Arthritis Rheum 2004;50:3831–43.
  • Wijbrandts CA, Klaasen R, Dijkgraaf MGW, Gerlag DM, van Eck-Smit BLF, Tak PP. Bone mineral density in rheumatoid arthritis patients 1 year after adalimumab therapy: arrest of bone loss. Ann Rheum Dis 2009;68:373–6.
  • Dischereit G, Tarner IH, Müller-Ladner U, Lange U. Infliximab improves bone metabolism and bone mineral density in rheumatoid arthritis and ankylosing spondylitis: a prospective 2-year study. Clin Rheumatol 2013;32:377–81.
  • Güler-Yuksel M, Bijsterbosch J, Goekoop-Ruiterman YP, de Vries-Bouwstra JK, Hulsmans HM, de Beus WM, et al. Changes in bone mineral density in patients with recent onset, active rheumatoid arthritis. Ann Rheum Dis 2008;67:823–8.
  • Kim SY, Schneeweiss S, Liu J, Solomon DH. Effects of disease-modifying antirheumatic drugs on nonvertebral fracture risk in rheumatoid arthritis: a population-based cohort study. J Bone Miner Res 2012;27:789–96.
  • Hauser B, Riches PL, Wilson JF, Horne AE, Ralston SH. Prevalence and clinical prediction of osteoporosis in a contemporary cohort of patients with rheumatoid arthritis. Rheumatology (Oxford) 2014;53:1759–66.
  • Kim D, Cho SK, Choi CB, Jun JB, Kim TH, Lee HS, et al. Incidence and risk factors of fractures in patients with rheumatoid arthritis: an Asian prospective cohort study. Rheumatol Int 2016;36:1205–14.
  • Cooper C. The crippling consequences of fractures and their impact on quality of life. Am J Med 1997;103:12S–19S.
  • Bergstrom F, Sobocki P, Strom O, Jonsson B. The societal burden of osteoporosis in Sweden. Bone 2007;40:1602–9.
  • Michaud K, Wolfe F. Comorbidities in rheumatoid arthritis. Best Pract Res Clin Rheumatol 2007;21:885–906.
  • Svensson B, Schaufelberger C, Teleman A, Theander J. Remission and response to early treatment of RA assessed by the Disease Activity Score. BARFOT study group. Rheumatology (Oxford) 2000;39:1031–6.
  • Arnett FC, Edworthy SM, Bloch DA, McShane DJ, Fries JF, Cooper NS, et al. The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis. Arthritis Rheum 1988;31:315–24.
  • Ludvigsson JF, Andersson E, Ekbom A, Feychting M, Kim JL, Reuterwall C, et al. External review and validation of the Swedish national inpatient register. BMC Public Health 2011;11:450.
  • Prevoo ML, Van’t Hof MA, Kuper HH, van Leeuwen MA, van de Putte LB, van Riel PL. Modified disease activity scores that include twenty-eight-joint counts. Development and validation in a prospective longitudinal study of patients with rheumatoid arthritis. Arthritis Rheum 1995;38:44–8.
  • Ekdahl C, Eberhardt K, Andersson SI, Svensson B. Assessing disability in patients with rheumatoid arthritis. Use of a Swedish version of the Stanford Health Assessment Questionnaire. Scand J Rheumatol 1988;17:263–71.
  • Wright NC, Lisse JR, Walitt BT, Eaton CB, Chen Z. Arthritis increases the risk for fractures - results from the Women´s Health Initiative. J Rheumatol 2011;38:1680–8.
  • Andersson MLE, Forslind K, Hafström I. Comparing five year out-come in two cohorts of patients with early rheumatoid arthritis – a BARFOT study. Open Rheumatol J 2015;9:8–15.
  • Andersson MLE, Forslind K, Hafstrom I. Patients with early rheumatoid arthritis in the 2000s have equal disability and pain despite less disease activity compared with the 1990s: data from the BARFOT study over 8 years. J Rheumatol 2017;44:723–31.
  • Ghazi M, Kolta S, Briot K, Fechtenbaum J, Paternotte S, Roux C. Prevalence of vertebral fractures in patients with rheumatoid arthritis: revisiting the role of glucocorticoids. Osteoporos Int 2012;23:581–7.
  • Van Staa TP, Laan RF, Barton IP, Cohen S, Reid DM, Cooper C. Bone density threshold and other predictors of vertebral fracture in patients receiving oral glucocorticoid therapy. Arthritis Rheum 2003;48:3224–9.
  • Engvall IL, Svensson B, Tengstrand B, Brismar K, Hafström I. Better Anti-Rheumatic FarmacO Therapy Study Group. Impact of low-dose prednisolone on bone synthesis and resorption in early rheumatoid arthritis: experiences from a two-year randomized study. Arthritis Res Ther 2008;10:R128.
  • Maricic M. Use of DXA-based technology for detection and assessment of risk of vertebral fracture in rheumatology practice. Curr Rheumatol Rep 2014;16:436.
  • Malgo F, Appelman-Dijkstra NM, Termaat MF, van der Heide HJL, Schipper IB, Rabelink TJ, et al. High prevalence of secondary factors for bone fragility in patients with a recent fracture independently of BMD. Arch Osteoporos 2016;11:12.
  • Smulders E, Schreven C, Weerdesteyn V, van den Hoogen FHJ, Laan R, Van Lankveld W. Fall incidence and fall risk factors in people with rheumatoid arthritis. Ann Rheum Dis 2009;68:1795–6.
  • Delmas PD, van de Langerijt L, Watts NB, Eastell R, Genant H, Grauer A, et al. Underdiagnosis of VFs is a worldwide problem: the IMPACT study. J Bone Miner Res 2005;20:557–63.

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