Etanercept therapy leads to reductions in matrix metalloproteinase-3 in patients with erosive hand osteoarthritis

FPB KroonDepartment of Rheumatology, Leiden University Medical Center, Leiden, The NetherlandsCorrespondence[email protected]
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AC Bay-JensenBiomarker and Research, Nordic Bioscience, Herlev, DenmarkView further author information

R WittoekDepartment of Rheumatology, Ghent University Hospital, Ghent, BelgiumView further author information

G VerbruggenDepartment of Rheumatology, Ghent University Hospital, Ghent, BelgiumView further author information

JS SmolenDivision of Rheumatology, Department of Internal Medicine III, Medical University of Vienna, Vienna, AustriaView further author information

M KloppenburgDepartment of Rheumatology, Leiden University Medical Center, Leiden, The Netherlands;Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, The NetherlandsView further author information

R RamondaRheumatology Unit, Department of Medicine DIMED, University of Padua, Padua, ItalyView further author information

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References

Lennerova T, Pavelka K, Senolt L. Biomarkers of hand osteoarthritis. Rheumatol Int 2018;38:725–35.
PubMed Web of Science ®Google Scholar
Kloppenburg M, Maheu E, Kraus VB, Cicuttini F, Doherty M, Dreiser RL, et al. OARSI clinical trials recommendations: design and conduct of clinical trials for hand osteoarthritis. Osteoarthritis Cartilage 2015;23:772–86.
PubMed Web of Science ®Google Scholar
Ramonda R, Lorenzin M, Modesti V, Campana C, Ortolan A, Frallonardo P, et al. Serological markers of erosive hand osteoarthritis. Eur J Intern Med 2013;24:11–15.
PubMed Web of Science ®Google Scholar
Kloppenburg M, Ramonda R, Bobacz K, Kwok WY, Elewaut D, Huizinga TWJ, et al. Etanercept in patients with inflammatory hand osteoarthritis (EHOA): a multicentre, randomised, double-blind, placebo-controlled trial. Ann Rheum Dis 2018;77:1757–64.
PubMed Web of Science ®Google Scholar
Bondeson J, Blom AB, Wainwright S, Hughes C, Caterson B. van den Berg WB. The role of synovial macrophages and macrophage-produced mediators in driving inflammatory and destructive responses in osteoarthritis. Arthritis Rheum 2010;62:647–57.
PubMed Web of Science ®Google Scholar
Catrina AI, Lampa J, Ernestam S, Klint E, Bratt J, Klareskog L, et al. Anti-tumour necrosis factor (TNF)-alpha therapy (etanercept) down-regulates serum matrix metalloproteinase (MMP)-3 and MMP-1 in rheumatoid arthritis. Rheumatology (Oxford) 2002;41:484–9.
PubMed Web of Science ®Google Scholar

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Etanercept therapy leads to reductions in matrix metalloproteinase-3 in patients with erosive hand osteoarthritis

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Etanercept therapy leads to reductions in matrix metalloproteinase-3 in patients with erosive hand osteoarthritis

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