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Letters

Dantrolene, a ryanodine receptor stabilizer, is a candidate immunomodulator for treating rheumatic disease

ORCID Icon, , , , , , , , & show all
Pages 217-219 | Received 21 Nov 2023, Accepted 18 Dec 2023, Published online: 31 Jan 2024

References

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  • Nakamura Y, Yamamoto T, Xu X, Kobayashi S, Tanaka S, Tamitani M, et al. Enhancing calmodulin binding to ryanodine receptor is crucial to limit neuronal cell loss in Alzheimer disease. Sci Rep 2021;11:7289.
  • Tamitani M, Yamamoto T, Yamamoto N, Fujisawa K, Tanaka S, Nakamura Y, et al. Dantrolene prevents hepatic steatosis by reducing cytoplasmic Ca2+ level and ER stress. Biochem Biophys Rep 2020;23:100787.
  • Nawata T, Sakai H, Honda T, Otsuka M, Fujita H, Uchinoumi H, et al. Dantrolene, a stabilizer of the ryanodine receptor, prevents collagen-induced arthritis. Biochem Biophys Res Commun 2022;624:141–5.
  • Osipchuk NC, Soulika AM, Fomina AF. Modulation of ryanodine receptors activity alters the course of experimental autoimmune encephalomyelitis in mice. Front Physiol 2021;12:770820.
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