The benefit of using in vitro bioassays to screen agricultural samples for oxidative stress: South Africa’s case

References

• United Nations (UN), Department of Economic and Social Affairs, Population Division. Population 2030: Demographic challenges and opportunities for sustainable development planning (ST/ESA/SER.A/389). 2015.
   Google Scholar
• United Nations (UN), Department of Economic and Social Affairs, Population Division. World population prospects 2019: Highlights (ST/ESA/SER.A/423). 2019.
   Google Scholar
• Baruah, P.; Chaurasia, N. Ecotoxicological Effects of Alpha-Cypermethrin on Freshwater Alga Chlorella sp.: Growth Inhibition and Oxidative Stress Studies. Environ. Toxicol. Pharmacol. 2020, 76, 103347. DOI: 10.1016/j.etap.2020.103347.
   PubMed Web of Science ®Google Scholar
• Rother, H. A. Falling through the Regulatory Cracks Street Selling of Pesticides and Poisoning among Urban Youth in South Africa. Int. J. Occu. Environ. Health 2010, 16, 183–194. DOI: 10.1179/oeh.2010.16.2.183.
   Web of Science ®Google Scholar
• Dalvie, M. A.; Sosan, M.; B; Africa, A.; Cairncross, E.; London, L. Environmental Monitoring of Pesticide Residues from Farms at a Neighbouring Primary and Pre-School in the Western Cape in South Africa. Sci. Total Environ. 2014, 466–467, 1078–1084. DOI: 10.1016/j.scitotenv.2013.07.099.
   PubMed Web of Science ®Google Scholar
• Degrendele, C.; Okonski, K.; Melymuk, L.; Landlová, L.; Kukučka, P.; Audy, O.; Kohoutek, J.; Čupr, P.; Klánová, J. Pesticides in the Atmosphere: A Comparison of Gas-Particle Partitioning and Particle Size Distribution of Legacy and Current-Use Pesticides. Atmos. Chem. Phys. 2016, 16, 1531–1544. DOI: 10.5194/acp-16-1531-2016.
   Web of Science ®Google Scholar
• Basopo, N.; Muzvidziwa, A. Assessment of the Effects of Atrazine, Dichlorodiphenyltrichloroethane, and Dimethoate on Freshwater Fish (Oreochromis Mossambicus): A Case Study of the A2 Farmlands in Chiredzi, in the Southeastern Part of Zimbabwe. Environ. Sci. Pollut. Res. Int. 2020, 27, 579–586. DOI: 10.1007/s11356-019-06569-x.
   PubMed Web of Science ®Google Scholar
• Dabrowski, J. M.; Peall, S. K. C.; Reinecke, A. J.; Liess, M.; Schulz, R. Runoff-Related Pesticide Input into the Lourens River, South Africa: Basic Data for Exposure Assessment and Risk Mitigation at the Catchment Scale. Water Air Soil Pollut. 2002, 135, 265–283. DOI: 10.1023/A:1014705931212.
   Web of Science ®Google Scholar
• Liu, X.; Zhang, R.; Jin, Y. Differential Responses of Larval Zebrafish to the Fungicide Propamocarb: Endpoints at Development, Locomotor Behavior and Oxidative Stress. Sci. Total Environ. 2020, 731, 139136. DOI: 10.1016/j.scitotenv.2020.139136.
   PubMed Web of Science ®Google Scholar
• Gevao, B.; Semple, K. T.; Jones, K. C. Bound Pesticide Residues in Soils: A Review. Environ. Pollut. 2000, 108, 3–14. DOI: 10.1016/S0269-7491(99)00197-9.
   PubMed Web of Science ®Google Scholar
• Mandal, A.; Sarkar, B.; Mandal, S.; Vithanage, M.; Patra, A.; Manna, M. C. Impact of Agrochemicals in Soil Health. In Agrochemicals Detection, Treatment and Remediation: Pesticides and Chemical Fertilizers; Prasad, M.N.V., Ed.; Butterworth-Heinemann: Oxford, 2020; 161–187 DOI: 10.1016/B978-0-08-103017-2.00007-6.
   Google Scholar
• Mamy, L.; Barriuso, E.; Gabrielle, B. Glyphosate Fate in Soils When Arriving in Plant Residues. Chemosphere 2016, 154, 425–433. DOI: 10.1016/j.chemosphere.2016.03.104.
   PubMed Web of Science ®Google Scholar
• United States Environmental Protection Agency (US EPA). Bioaccumulation Testing and Interpretation for the Purpose of Sediment Quality Assessment: Status and Needs. EPA-823-R-00-001. United States Environmental Protection Agency Bioaccumulation Analysis Workgroup, Washington, D.C. 2000.
   Google Scholar
• Nnadi, J. U.; Dimelu, IN.; Nwani, S. I.; Madu, J. C.; Atama, C. I.; Attamah, G. N.; Okwor, J. I.; Nwani, C. D. Biometric Variations and Oxidative Stress Responses in Juvenile Clarias Gariepinus Exposed to Termex®. Afr. J. Aquat. Sci. 2018, 43, 27–34. DOI: 10.2989/16085914.2018.1445615.
   Web of Science ®Google Scholar
• Semple, K. T.; Doick, K. J.; Jones, K. C.; Burauel, P.; Craven, A.; Harms, H. Defining Bioavailability and Bioaccessibility of Contaminated Soil and Sediment is Complicated. Environ. Sci. Technol. 2004, 38, 228A–231A. DOI: 10.1021/es040548w.
   PubMed Web of Science ®Google Scholar
• Van der Oost, R.; Beyer, J.; Vermeulen, N. P. E. Fish Bioaccumulation and Biomarkers in Environmental Risk Assessment: A Review. Environ. Toxicol. Pharmacol. 2003, 13, 57–149. DOI: 10.1016/S1382-6689(02)00126-6.
   PubMed Web of Science ®Google Scholar
• United States National Research Council (US NRC). Bioavailability of Contaminants in Soils and Sediments: Processes, Tools, and Applications. Washington, D.C., United States of America: The National Academies Press. 2003.
   Google Scholar
• Clasen, B.; Loro, V. L.; Murussi, C. R.; Tiecher, T. L.; Moraes, B.; Zanella, R. Bioaccumulation and Oxidative Stress Caused by Pesticides in Cyprinus Carpio Reared in a Rice-Fish System. Sci. Total Environ. 2018, 626, 737–743. DOI: 10.1016/j.scitotenv.2018.01.154.
   PubMed Web of Science ®Google Scholar
• Ojemaye, C. Y.; Onwordi, C. T.; Pampanin, D. M.; Sydnes, M. O.; Petrik, L. Presence and Risk Assessment of Herbicides in the Marine Environment of Camps Bay (Cape Town, South Africa). Sci. Total Environ. 2020, 738, 140346. DOI: 10.1016/j.scitotenv.2020.140346.
   PubMed Web of Science ®Google Scholar
• Barnhoorn, I. E. J.; van Dyk, J. C.; Genthe, B.; Harding, W. R.; Wagenaar, G. M.; Bornman, M. S. Organochlorine Pesticide Levels in Clarias Gariepinus from Polluted Freshwater Impoundments in South Africa and Associated Human Health Risks. Chemosphere 2015, 120, 391–397. DOI: 10.1016/j.chemosphere.2014.08.030.
   PubMed Web of Science ®Google Scholar
• Pheiffer, W.; Wolmarans, N. J.; Gerber, R.; Yohannes, Y. B.; Ikenaka, Y.; Ishizuka, M.; Smit, N. J.; Wepener, V.; Pieters, R. Fish Consumption from Urban Impoundments: What Are the Health Risks Associated with DDTs and Other Organochlorine Pesticides in Fish to Township Residents of a Major Inland City. Sci. Total Environ. 2018, 628-629, 517–527. DOI: 10.1016/j.scitotenv.2018.02.075.
   PubMed Web of Science ®Google Scholar
• Wolmarans, N. J.; Du Preez, L. H.; Yohannes, Y. B.; Ikenaka, Y.; Ishizuka, M.; Smit, N. J.; Wepener, V. Linking Organochlorine Exposure to Biomarker Response Patterns in Anurans: A Case Study of Müller’s Clawed Frog (Xenopus Muelleri) from a Tropical Malaria Vector Control Region. Ecotoxicology 2018, 27, 1203–1216. DOI: 10.1007/s10646-018-1972-y.
   PubMed Web of Science ®Google Scholar
• Bouwman, H.; Govender, D.; Underhill, L.; Polder, A. Chlorinated, Brominated and Fluorinated Organic Pollutants in African Penguin Eggs: 30 Years since the Previous Assessment. Chemosphere 2015, 126, 1–10. DOI: 10.1016/j.chemosphere.2014.12.071.
   PubMed Web of Science ®Google Scholar
• Bouwman, H.; Yohannes, Y. B.; Nakayama, S. M. M.; Motohira, K.; Ishizuka, M.; Humphries, M. S.; van der Schyff, V.; Du Preez, M.; Dinkelmann, A.; Ikenaka, Y. Evidence of Impacts from DDT in Pelican, Cormorant, Stork, and Egret Eggs from KwaZulu-Natal, South Africa. Chemosphere 2019, 225, 647–658. DOI: 10.1016/j.chemosphere.2019.03.043.
   PubMed Web of Science ®Google Scholar
• Dalvie, M. A.; Cairncross, E.; Solomon, A.; London, L. Contamination of Rural Surface and Ground Water by Endosulfan in Farming Areas of the Western Cape, South Africa. Environ. Health 2003, 2, 1–15. DOI: 10.1186/1476-069X-2-1.
   PubMedGoogle Scholar
• Fatoki, O. S.; Awofolu, O. R. Levels of Organochlorine Pesticide Residues in Marine-, Surface-, Ground- and Drinking Waters from the Eastern Cape Province of South Africa. J. Environ. Sci. Health B 2004, 39, 101–114. DOI: 10.1081/PFC-120027442.
   PubMed Web of Science ®Google Scholar
• Adeyinka, G. C.; Moodley, B.; Birungi, G.; Ndungu, P. Evaluation of Organochlorinated Pesticide (OCP) Residues in Soil, Sediment and Water from the Msunduzi River in South Africa. Environ. Earth Sci. 2019, 78, 223. DOI: 10.1007/s12665-019-8227-y.
   Web of Science ®Google Scholar
• Gerber, R.; Smit, N. J.; van Vuren, J. H. J.; Nakayama, S. M. M.; Yohannes, Y. B.; Ikenaka, Y.; Ishizuka, M.; Wepener, V. Application of a Sediment Quality Index for the Assessment and Monitoring of Metals and Organochlorines in a Premier Conservation Area. Environ. Sci. Pollut. Res. Int. 2015, 22, 19971–19989. DOI: 10.1007/s11356-015-5206-z.
   PubMed Web of Science ®Google Scholar
• Vogt, T.; Pieters, R.; Newman, B. K. PAHs, OCPs and PCBs in Sediments from Three Catchments in Durban, South Africa. Afr. J. Aquat. Sci. 2018, 43, 35–49. DOI: 10.2989/16085914.2018.1445616.
   Web of Science ®Google Scholar
• Degrendele, C.; Klánová, J.; Prokeš, R.; Příbylová, P.; Šenk, P.; Šudoma, M.; Röösli, M.; Dalvie, M. A.; Fuhrimann, S. Current Use Pesticides in Soil and Air from Two Agricultural Sites in South Africa: Implications for Environmental Fate and Human Exposure. Sci. Total Environ. 2022, 807, 150455. DOI: 10.1016/j.scitotenv.2021.150455.
   PubMed Web of Science ®Google Scholar
• Department of Water Affairs and Forestry (DWAF). South African Water Quality Guidelines. 2nd Edition. Department of Water Affairs and Forestry. Pretoria, South Africa. 1996.
   Google Scholar
• South African National Standards (SANS) 241-1. Drinking Water. Part 1: Microbiological, Physical, Aesthetic and Chemical Determinands. 2nd Edition. South African Bureau of Standards. Pretoria, South Africa. 2015.
   Google Scholar
• Dabrowski, J. M.; Schachtschneider, K.; Ross, T. A.; Bollmohr, S.; Thwala, M. Development of an indicator methodology to estimate the relative exposure and risk of pesticides in South African surface waters. Water Research Commission Report No. 1854/1/11. Water Research Commission. Pretoria, South Africa. 2011.
   Google Scholar
• Food and Agricultural Organisation of the United Nations (FAO). Statistics division – pesticide use. https://www.fao.org/faostat/en/#data/RP/visualize. Accessed March 23, 2022.
   Google Scholar
• Dabrowski, J. M.; Shadung, J. M.; Wepener, V. Prioritizing Agricultural Pesticides Used in South Africa Based on Their Environmental Mobility and Potential Human Health Effects. Environ. Int. 2014, 62, 31–40. DOI: 10.1016/j.envint.2013.10.001.
   PubMed Web of Science ®Google Scholar
• Murray, K.; Slabbert, L.; Moloi, B. Needs Assessment and Development Framework for a Tested Implementation Plan for the Initialisation and Execution of a National Toxicants Monitoring Programme (NTMP). Department of Water Affairs and Forestry. Pretoria, South Africa. 2003.
   Google Scholar
• Jooste, S.; Bollmohr, S.; Thwala, M. National Toxicity Monitoring Program: Report on phase 3: Pilot implementation and testing of the design. Report No. N/0000/REQ1008. Department of Water Affairs and Forestry. Pretoria, South Africa. 2008.
   Google Scholar
• Kruger, A.; Pieters, R.; Horn, S.; van Zijl, C.; Aneck-Hahn, N. The Role of Effect-Based Methods to Address Water Quality Monitoring in South Africa: A Developing Country’s Struggle. Environ. Sci. Pollut. Res. Int. 2022, 29, 84049–84055. DOI: 10.1007/s11356-022-23534-3.
   PubMed Web of Science ®Google Scholar
• Ojha, A.; Yaduvanshi, S. K.; Srivastava, N. Effect of Combined Exposure of Commonly Used Organophosphate Pesticides on Lipid Peroxidation and Antioxidant Enzymes in Rat Tissues. Pest. Biochem. Physiol. 2011, 99, 148–156. DOI: 10.1016/j.pestbp.2010.11.011.
   Web of Science ®Google Scholar
• Phaniendra, A.; Jestadi, D. B.; Periyasamy, L. Free Radicals: Properties, Sources, Targets, and Their Implication in Various Diseases. Indian J. Clin. Biochem. 2015, 30, 11–26. DOI: 10.1007/s12291-014-0446-0.
   PubMed Web of Science ®Google Scholar
• Pisoschi, A. M.; Pop, A. The Role of Antioxidants in the Chemistry of Oxidative Stress: A Review. Eur. J. Med. Chem. 2015, 97, 55–74. DOI: 10.1016/j.ejmech.2015.04.040.
   PubMed Web of Science ®Google Scholar
• Cortés-Iza, S. C.; Rodríguez, A. I. Oxidative Stress and Pesticide Disease: A Challenge for Toxicology. Rev. Fac. Med. 2018, 66, 261–267. DOI: 10.15446/revfacmed.v66n2.60783.
   Google Scholar
• Jabłońska-Trypuć, A.; Wołejko, E.; Wydro, U.; Butarewicz, A. The Impact of Pesticides on Oxidative Stress Level in Human Organism and Their Activity as an Endocrine Disruptor. J. Environ. Sci. Health B 2017, 52, 483–494. DOI: 10.1080/03601234.2017.1303322.
   PubMed Web of Science ®Google Scholar
• Ventura, C.; Venturino, A.; Miret, N.; Randi, A.; Rivera, E.; Núñez, M.; Cocca, C. Chlorpyrifos Inhibits Cell Proliferation through ERK1/2 Phosphorylation in Breast Cancer Cell Lines. Chemosphere 2015, 120, 343–350. DOI: 10.1016/j.chemosphere.2014.07.088.
   PubMed Web of Science ®Google Scholar
• Zhang, W.; Xia, X.; Wang, J.; Zhu, L.; Wang, J.; Wang, G.; Chen, Y.; Kim, Y. M. Oxidative Stress and Genotoxicity of Nitenpyram to Earthworms (Eisenia Foetida). Chemosphere 2021, 264, 128493. DOI: 10.1016/j.chemosphere.2020.128493.
   PubMed Web of Science ®Google Scholar
• Rahal, A.; Kumar, A.; Singh, V.; Yadav, B.; Tiwari, R.; Chakraborty, S.; Dhama, K. Oxidative Stress, Prooxidants, and Antioxidants: The Interplay. Biomed. Res. Int. 2014, 2014, 761264. DOI: 10.1155/2014/761264.
   PubMed Web of Science ®Google Scholar
• Archibong, A. E.; Rideout, M. L.; Harris, K. J.; Ramesh, A. Oxidative Stress in Reproductive Toxicology. Curr. Opin. Toxicol. 2018, 7, 95–101. DOI: 10.1016/j.cotox.2017.10.004.
   PubMedGoogle Scholar
• Burella, P. M.; Odetti, L. M.; Simoniello, M. F.; Poletta, G. L. Oxidative Damage and Antioxidant Defense in Caiman Latirostris (Broad-Snouted Caiman) Exposed in Ovo to Pesticide Formulations. Ecotoxicol. Environ. Saf. 2018, 161, 437–443. DOI: 10.1016/j.ecoenv.2018.06.006.
   PubMed Web of Science ®Google Scholar
• Felício, A. A.; Freitas, J. S.; Scarin, J. B.; De Souza Ondei, L.; Teresa, F. B.; Schlenk, D.; De Almeida, E. A. Isolated and Mixed Effects of Diuron and Its Metabolites on Biotransformation Enzymes and Oxidative Stress Response of Nile Tilapia (Oreochromis Niloticus). Ecotoxicol. Environ. Saf. 2018, 149, 248–256. DOI: 10.1016/j.ecoenv.2017.12.009.
   PubMed Web of Science ®Google Scholar
• Basopo, N.; Langton, T. M.; Dumisani, M.; Yogeshkumar, S. N. Pollutant Mixtures as Stressors of Selected Enzyme Activities of the Aquatic Snail Helisoma Duryi. J. Environ. Chem. Ecotoxicol. 2014, 6, 27–37. DOI: 10.5897/JECE2013.0319.
   Google Scholar
• Chang, X.; Wang, X.; Feng, J.; Su, X.; Liang, J.; Li, H.; Zhang, J. Impact of Chronic Exposure to Trichlorfon on Intestinal Barrier, Oxidative Stress, Inflammatory Response and Intestinal Microbiome in Common Carp (Cyprinus Carpio L.). Environ. Pollut. 2020, 259, 113846. DOI: 10.1016/j.envpol.2019.113846.
   PubMed Web of Science ®Google Scholar
• Ansari, S.; Ansari, B. A. Temporal Variations of CAT, GSH, and LPO in Gills and Livers of Zebrafish, Danio rerio, Exposed to Dimethoate. Arch. Pol. Fish. 2014, 22, 101–109. DOI: 10.2478/aopf-2014-0009.
   Google Scholar
• Gaki, G. S.; Papavassiliou, A. G. Oxidative Stress-Induced Signaling Pathways Implicated in the Pathogenesis of Parkinson’s Disease. Neuromol. Med. 2014, 16, 217–230. DOI: 10.1007/s12017-014-8294-x.
   PubMed Web of Science ®Google Scholar
• Hayes, J. D.; Dinkova-Kostova, A. T.; Tew, K. D. Oxidative Stress in Cancer. Cancer Cell 2020, 38, 167–197. DOI: 10.1016/j.ccell.2020.06.001.
   PubMed Web of Science ®Google Scholar
• Huang, W.-J.; Zhang, X.; Chen, W.-W. Role of Oxidative Stress in Alzheimer’s Disease. Biomed. Rep. 2016, 4, 519–522. DOI: 10.3892/br.2016.630.
   PubMed Web of Science ®Google Scholar
• Zhang, S. Y.; Gui, L. N.; Liu, Y. Y.; Shi, S.; Cheng, Y. Oxidative Stress Marker Aberrations in Multiple Sclerosis: A Meta-Analysis Study. Front. Neurosci. 2020, 14, 823. DOI: 10.3389/fnins.2020.00823.
   PubMed Web of Science ®Google Scholar
• Diken, M. E.; Dogan, S.; Dogan, M.; Turhan, Y. In Vitro Effects of Some Pesticides on glutathione-S-Transferase Activity. Fresenius Environ. Bull. 2017, 26, 8023–8029.
   Web of Science ®Google Scholar
• Nwani, C. D.; Nagpure, N. S.; Kumar, R.; Kushwaha, B.; Lakra, W. S. DNA Damage and Oxidative Stress Modulatory Effects of Glyphosate-Based Herbicide in Freshwater Fish, Channa Punctatus. Environ. Toxicol. Pharmacol. 2013, 36, 539–547. DOI: 10.1016/j.etap.2013.06.001.
   PubMed Web of Science ®Google Scholar
• Agrawal, A.; Sharma, B. Pesticides Induced Oxidative Stress in Mammalian Systems. IJBMR 2010, 1, 90–104.
   Google Scholar
• Pisoschi, A. M.; Pop, A.; Iordache, F.; Stanca, L.; Predoi, G.; Serban, A. I. Oxidative Stress Mitigation by antioxidants - An Overview on Their Chemistry and Influences on Health Status. Eur. J. Med. Chem. 2021, 209, 112891. DOI: 10.1016/j.ejmech.2020.112891.
   PubMed Web of Science ®Google Scholar
• Elsharkawy, E. E.; Yahia, D.; El-Nisr, N. A. Sub-Chronic Exposure to Chlorpyrifos Induces Hematological, Metabolic Disorders and Oxidative Stress in Rat: attenuation by Glutathione. Environ. Toxicol. Pharmacol. 2013, 35, 218–227. DOI: 10.1016/j.etap.2012.12.009.
   PubMed Web of Science ®Google Scholar
• Khalil, A. M. 2015 Toxicological Effects and Oxidative Stress Responses in Freshwater Snail, Lanistes Carinatus, following Exposure to Chlorpyrifos. Ecotoxicol. Environ. Saf. 2015, 116, 137–142. DOI: 10.1016/j.ecoenv.2015.03.010.
   PubMed Web of Science ®Google Scholar
• Lu, S. C. Regulation of Glutathione Synthesis. Curr. Top. Cell. Regul. 2000, 36, 95–116. DOI: 10.1016/S0070-2137(01)80004-2.
   PubMedGoogle Scholar
• Jin, Y.; Liu, Z.; Peng, T.; Fu, Z. The Toxicity of Chlorpyrifos on the Early Life Stage of Zebrafish: A Survey on the Endpoints at Development, Locomotor Behavior, Oxidative Stress and Immunotoxicity. Fish Shellfish Immunol. 2015, 43, 405–414. DOI: 10.1016/j.fsi.2015.01.010.
   PubMed Web of Science ®Google Scholar
• Lushchak, V. I.; Matviishyn, T. M.; Husak, V. V.; Storey, J. M.; Storey, K. B. Pesticide Toxicity: A Mechanistic Approach. Excli. J. 2018, 17, 1101–1136. DOI: 10.17179/excli2018-1710.
   PubMed Web of Science ®Google Scholar
• Serdar, O. The Effect of Dimethoate Pesticide on Some Biochemical Biomarkers in Gammarus Pulex. Environ. Sci. Pollut. Res. Int. 2019, 26, 21905–21914. DOI: 10.1007/s11356-019-04629-w.
   PubMed Web of Science ®Google Scholar
• Taju, G.; Abdul Majeed, S.; Nambi, K. S. N.; Farook, M. A.; Vimal, S.; Sahul Hameed, A. S. In Vitro Cytotoxic, Genotoxic and Oxidative Stress of Cypermethrin on Five Fish Cell Lines. Pest. Biochem. Physiol. 2014, 113, 15–24. DOI: 10.1016/j.pestbp.2014.06.006.
   PubMed Web of Science ®Google Scholar
• JanakiDevi, V.; Nagarani, N.; YokeshBabu, M.; Kumaraguru, A. K.; Ramakritinan, C. M. A Study of Proteotoxicity and Genotoxicity Induced by the Pesticide and Fungicide on Marine Invertebrate (Donax Faba). Chemosphere 2013, 90, 1158–1166. DOI: 10.1016/j.chemosphere.2012.09.024.
   PubMed Web of Science ®Google Scholar
• Limón-Pacheco, J.; Gonsebatt, M. E. The Role of Antioxidants and Antioxidant-Related Enzymes in Protective Responses to Environmentally Induced Oxidative Stress. Mutat. Res. 2009, 674, 137–147. DOI: 10.1016/j.mrgentox.2008.09.015.
   PubMed Web of Science ®Google Scholar
• McCord, J. M.; Fridovich, I. Superoxide dismutase - An Enzymatic Function for Erythrocuprein (Hemocuprein). J. Biol. Chem. 1969, 244, 6049–6055. DOI: 10.1016/S0021-9258(18)63504-5.
   PubMed Web of Science ®Google Scholar
• Chance, B. The Enzyme-Substrate Compounds of Catalase and Peroxides. Nat 1948, 161, 914–917. DOI: 10.1038/161914a0.
   Google Scholar
• Hattab, S.; Boughattas, I.; Boussetta, H.; Viarengo, A.; Banni, M.; Sforzini, S. Transcriptional Expression Levels and Biochemical Markers of Oxidative Stress in the Earthworm Eisenia Andrei after Exposure to 2,4-Dichlorophenoxyacetic Acid (2,4-D). Ecotoxicol. Environ. Saf. 2015, 122, 76–82. DOI: 10.1016/j.ecoenv.2015.07.014.
   PubMed Web of Science ®Google Scholar
• Yonar, M. E. Chlorpyrifos-Induced Biochemical Changes in Cyprinus Carpio: Ameliorative Effect of Curcumin. Ecotoxicol. Environ. Saf. 2018, 151, 49–54. DOI: 10.1016/j.ecoenv.2017.12.065.
   PubMed Web of Science ®Google Scholar
• Kaur, M.; Jindal, R. Oxidative Stress Response in Liver, Kidney and Gills of Ctenopharyngodon Idellus (Cuvier & Valenciennes) Exposed to Chlorpyrifos. MOJBM 2017, 1, 103–112. DOI: 10.15406/mojbm.2017.01.00021.
   Google Scholar
• Gaaied, S.; Oliveira, M.; Le Bihanic, F.; Cachot, J.; Banni, M. Gene Expression Patterns and Related Enzymatic Activities of Detoxification and Oxidative Stress Systems in Zebrafish Larvae Exposed to the 2,4-Dichlorophenoxyacetic Acid Herbicide. Chemosphere 2019, 224, 289–297. DOI: 10.1016/j.chemosphere.2019.02.125.
   PubMed Web of Science ®Google Scholar
• Ilboudo, S.; Fouche, E.; Rizzati, V.; Toé, A. M.; Gamet-Payrastre, L.; Guissou, P. I. In Vitro Impact of Five Pesticides Alone or in Combination on Human Intestinal Cell Line Caco-2. Toxicol. Rep. 2014, 1, 474–489. DOI: 10.1016/j.toxrep.2014.07.008.
   PubMedGoogle Scholar
• Katerji, M.; Filippova, M.; Duerksen-Hughes, P. Approaches and Methods to Measure Oxidative Stress in Clinical Samples: Research Applications in the Cancer Field. Oxid. Med. Cell Longev. 2019, 2019, 1279250. DOI: 10.1155/2019/1279250.
   PubMed Web of Science ®Google Scholar
• Stara, A.; Machova, J.; Velisek, J. Effect of Chronic Exposure to Simazine on Oxidative Stress and Antioxidant Response in Common Carp (Cyprinus Carpio L.). Environ. Toxicol. Pharmacol. 2012, 33, 334–343. DOI: 10.1016/j.etap.2011.12.019.
   PubMed Web of Science ®Google Scholar
• Griboff, J.; Morales, D.; Bertrand, L.; Bonansea, R. I.; Monferrán, M. V.; Asis, R.; Wunderlin, D. A.; Amé, M. V. Oxidative Stress Response Induced by Atrazine in Palaemonetes Argentinus: The Protective Effect of Vitamin E. Ecotoxicol. Environ. Saf. 2014, 108, 1–8. DOI: 10.1016/j.ecoenv.2014.06.025.
   PubMed Web of Science ®Google Scholar
• Couto, N.; Wood, J.; Barber, J. The Role of Glutathione Reductase and Related Enzymes on Cellular Redox Homoeostasis Network. Free Radic. Biol. Med. 2016, 95, 27–42. DOI: 10.1016/j.freeradbiomed.2016.02.028.
   PubMed Web of Science ®Google Scholar
• Mossa, A.-T. H.; Swelam, E. S.; Mohafrash, S. M. M. Sub-Chronic Exposure to Fipronil Induced Oxidative Stress, Biochemical and Histopathological Changes in the Liver and Kidney of Male Albino Rats. Toxicol. Rep. 2015, 2, 775–784. DOI: 10.1016/j.toxrep.2015.02.009.
   PubMed Web of Science ®Google Scholar
• Topal, A.; Alak, G.; Ozkaraca, M.; Yeltekin, A. C.; Comaklı, S.; Acıl, G.; Kokturk, M.; Atamanalp, M. Neurotoxic Responses in Brain Tissues of Rainbow Trout Exposed to Imidacloprid Pesticide: Assessment of 8-Hydroxy-2-Deoxyguanosine Activity, Oxidative Stress and Acetylcholinesterase Activity. Chemosphere 2017, 175, 186–191. DOI: 10.1016/j.chemosphere.2017.02.047.
   PubMed Web of Science ®Google Scholar
• Halliwell, B.; Whiteman, M. Measuring Reactive Species and Oxidative Damage in Vivo and in Cell Culture: How Should You Do It and What Do the Results Mean? Br. J. Pharmacol. 2004, 142, 231–255. DOI: 10.1038/sj.bjp.0705776.
   PubMed Web of Science ®Google Scholar
• Sparks, C.; Marnewick, J.; Toefy, R.; Snyman, R.; Odendaal, J. Baseline Levels of Antioxidant Activities in Mytilus Galloprovincialis along the Coast of Cape Town, South Africa. Mar. Pollut. Bull. 2019, 140, 287–293. DOI: 10.1016/j.marpolbul.2019.01.059.
   PubMed Web of Science ®Google Scholar
• Dar, S. A.; Yousuf, A. R.; Balkhi, M.-H.; Ganai, F. A.; Bhat, F. A. Assessment of Endosulfan Induced Genotoxicity and Mutagenicity Manifested by Oxidative Stress Pathways in Freshwater Cyprinid Fish Crucian Carp (Carassius Carassius L.). Chemosphere 2015, 120, 273–283. DOI: 10.1016/j.chemosphere.2014.07.031.
   PubMed Web of Science ®Google Scholar
• Jang, Y.; Lee, A. Y.; Jeong, S. H.; Park, K. H.; Paik, M. K.; Cho, N. J.; Kim, J. E.; Cho, M. H. Chlorpyrifos Induces NLRP3 Inflammasome and Pyroptosis/Apoptosis via Mitochondrial Oxidative Stress in Human Keratinocyte HaCaT Cells. Toxicology 2015, 338, 37–46. DOI: 10.1016/j.tox.2015.09.006.
   PubMed Web of Science ®Google Scholar
• Njattuvetty Chandran, N.; Fojtova, D.; Blahova, L.; Rozmankova, E.; Blaha, L. Acute and (Sub)Chronic Toxicity of the Neonicotinoid Imidacloprid on Chironomus Riparius. Chemosphere 2018, 209, 568–577. DOI: 10.1016/j.chemosphere.2018.06.102.
   PubMed Web of Science ®Google Scholar
• Othmène, Y.; Ben Hamdi, H.; Amara, I.; Abid-Essefi, S. Tebuconazole Induced Oxidative Stress and Histopathological Alterations in Adult Rat Heart. Pest. Biochem. Physiol. 2020, 170, 104671. DOI: 10.1016/j.pestbp.2020.104671.
   PubMed Web of Science ®Google Scholar
• Rubini, E.; Paglia, G.; Cannella, D.; Macone, A.; Di Sotto, A.; Gullì, M.; Altieri, F.; Eufemi, M. β-Hexachlorocyclohexane: A Small Molecule with a Big Impact on Human Cellular Biochemistry. Biomedicines 2020, 8, 505. DOI: 10.3390/biomedicines8110505.
   PubMed Web of Science ®Google Scholar
• Bindoli, A. Lipid Peroxidation in Mitochondria. Free Radic. Biol. Med. 1988, 5, 247–261. DOI: 10.1016/0891-5849(88)90018-4.
   PubMed Web of Science ®Google Scholar
• Mensah, P. K.; Palmer, C. G.; Muller, W. J. Lipid Peroxidation in the Freshwater Shrimp Caridina Nilotica as a Biomarker of Roundup® Herbicide Pollution of Freshwater Systems in South Africa. Water Sci. Technol. 2012, 65, 1660–1666. DOI: 10.2166/wst.2012.060.
   PubMed Web of Science ®Google Scholar
• Connell, L.; Jansen van Rensburg, G.; Avenant-Oldewage, A.; Greenfield, R. Biomarker Responses in African Sharptooth Catfish, Clarias Gariepinus (Burchell, 1822), as Indicators of Potential Metal and Organic Pollution along the Vaal River System, South Africa. Afr. J. Aquat. Sci. 2020, 45, 317–328. DOI: 10.2989/16085914.2020.1735296.
   Google Scholar
• Richardson, N.; Gordon, A.; Muller, W.; Pletschke, B.; Whitfield, A. The Use of Liver Histopathology, Lipid Peroxidation and Acetylcholinesterase Assays as Biomarkers of Contaminant-Induced Stress in the Cape Stumpnose, Rhabdosargus Holubi (Teleostei: Sparidae), from Selected South African Estuaries. WSA 2010, 36, 407–416. DOI: 10.4314/wsa.v36i4.58409.
   Web of Science ®Google Scholar
• Semren, T. Ž.; Žunec, S.; Pizent, A. Oxidative Stress in Triazine Pesticide Toxicity: A Review of the Main Biomarker Findings. Arh Hig Rada Toksikol 2018, 69, 109–125. DOI: 10.2478/aiht-2018-69-3118.
   PubMed Web of Science ®Google Scholar
• Zhang, D.; Wu, Y.; Yuan, Y.; Liu, W.; Kuang, H.; Yang, J.; Yang, B.; Wu, L.; Zou, W.; Xu, C. Exposure to 2,4-Dichlorophenoxyacetic Acid Induces Oxidative Stress and Apoptosis in Mouse Testis. Pest. Biochem. Physiol. 2017, 141, 18–22. DOI: 10.1016/j.pestbp.2016.10.006.
   PubMed Web of Science ®Google Scholar
• Xu, W.; Yang, M.; Gao, J.; Zhang, Y.; Tao, L. Oxidative Stress and DNA Damage Induced by Spinosad Exposure in Spodoptera frugiperda Sf9 Cells. Food Agric. Immunol. 2018, 29, 171–181. DOI: 10.1080/09540105.2017.1364708.
   Web of Science ®Google Scholar
• Shah, H. K.; Sharma, T.; Banerjee, B. D. Organochlorine Pesticides Induce Inflammation, ROS Production, and DNA Damage in Human Epithelial Ovary Cells: An in Vitro Study. Chemosphere 2020, 246, 125691. DOI: 10.1016/j.chemosphere.2019.125691.
   PubMed Web of Science ®Google Scholar
• Tian, X.; Hong, X.; Yan, S.; Li, X.; Wu, H.; Lin, A.; Yang, W. Neonicotinoids Caused Oxidative Stress and DNA Damage in Juvenile Chinese Rare Minnows (Gobiocypris Rarus). Ecotoxicol. Environ. Saf. 2020, 197, 110566. DOI: 10.1016/j.ecoenv.2020.110566.
   PubMed Web of Science ®Google Scholar
• Zhang, C.; Li, X.-N.; Xiang, L.-R.; Qin, L.; Lin, J.; Li, J.-L. Atrazine Triggers Hepatic Oxidative Stress and Apoptosis in Quails (Coturnix C. coturnix) via Blocking Nrf2-Mediated Defense Response. Ecotoxicol. Environ. Saf. 2017, 137, 49–56. DOI: 10.1016/j.ecoenv.2016.11.016.
   PubMed Web of Science ®Google Scholar
• Stadtman, E. R. Oxidation of Proteins by Mixed-Function Oxidation Systems: Implication in Protein Turnover, Ageing and Neutrophil Function. Trends Biochem. Sci. 1986, 11, 11–12. DOI: 10.1016/0968-0004(86)90221-5.
   Web of Science ®Google Scholar
• Almroth, B. C.; Sturve, J.; Berglund, Å.; Förlin, L. Oxidative Damage in Eelpout (Zoarces Viviparus), Measured as Protein Carbonyls and TBARS, as Biomarkers. Aquat. Toxicol. 2005, 73, 171–180. DOI: 10.1016/j.aquatox.2005.03.007.
   PubMed Web of Science ®Google Scholar
• Havelkova, M.; Blahova, J.; Kroupova, H.; Randak, T.; Slatinska, I.; Leontovycova, D.; Grabic, R.; Pospisil, R.; Svobodova, Z. Biomarkers of Contaminant Exposure in Chub (Leuciscus Cephalus L.) - Biomonitoring of Major Rivers in the Czech Republic. Sensors (Basel) 2008, 8, 2589–2603. DOI: 10.3390/s8042589.
   PubMed Web of Science ®Google Scholar
• Nunes, M. E. M.; Müller, T. E.; Murussi, C.; do Amaral, A. M. B.; Gomes, J. L. C.; Marins, A. T.; Leitemperger, J.; Rodrigues, C. C. R.; Fiuza, T. L.; Costa, M. D.; et al. Oxidative Effects of the Acute Exposure to a Pesticide Mixture of Cypermethrin and Chlorpyrifos on Carp and Zebrafish – a Comparative Study. Comp. Biochem. Physiol. C Toxicol. Pharmacol. 2018, 206-207, 48–53. DOI: 10.1016/j.cbpc.2018.03.002.
   PubMed Web of Science ®Google Scholar
• Peakall, D. B. The Role of Biomarkers in Environmental Assessment (1). Introduction. Ecotoxicology 1994, 3, 157–160. DOI: 10.1007/BF00117080.
   PubMed Web of Science ®Google Scholar
• Wepener, V.; van Vuren, J. H. J.; Chatiza, F. P.; Mbizi, Z.; Slabbert, L.; Masola, B. Active Biomonitoring in Freshwater Environments: Early Warning Signals from Biomarkers in Assessing Biological Effects of Diffuse Sources of Pollutants. Phys. Chem. Earth 2005, 30, 751–761. DOI: 10.1016/j.pce.2005.08.018.
   Google Scholar
• Coalova, I.; del Carmen Ríos de Molina, M.; Chaufan, G. Influence of the Spray Adjuvant on the Toxicity Effects of a Glyphosate Formulation. Toxicol. In Vitro 2014, 28, 1306–1311. DOI: 10.1016/j.tiv.2014.06.014.
   PubMed Web of Science ®Google Scholar
• Huang, T.; Huang, Y.; Huang, Y.; Yang, Y.; Zhao, Y.; Martyniuk, C. J. Toxicity Assessment of the Herbicide Acetochlor in the Human Liver Carcinoma (HepG2) Cell Line. Chemosphere 2020, 243, 125345. DOI: 10.1016/j.chemosphere.2019.125345.
   PubMed Web of Science ®Google Scholar
• Connon, R. E.; Geist, J.; Werner, I. Effect-Based Tools for Monitoring and Predicting the Ecotoxicological Effects of Chemicals in the Aquatic Environment. Sensors (Basel) 2012, 12, 12741–12771. DOI: 10.3390/s120912741.
   PubMed Web of Science ®Google Scholar
• Escher, B.; Neale, P.; Leusch, F. Bioanalytical Tools in Water Quality Assessment; IWA Publishing: London, 2021.
   Google Scholar
• Abdel-Halim, K. Y.; Osman, S. R. Cytotoxicity and Oxidative Stress Responses of Imidacloprid and Glyphosate in Human Prostate Epithelial WPM-Y.1 Cell Line. J. Toxicol. 2020, 2020, 4364650. DOI: 10.1155/2020/4364650.
   PubMed Web of Science ®Google Scholar
• Chaufan, G.; Galvano, C.; Nieves, M.; Mudry, M. D.; Del Carmen Ríos de Molina, M.; Andrioli, N. B. Oxidative Response and Micronucleus Centromere Assay in HEp-2 Cells Exposed to Fungicide Iprodione. Chem. Res. Toxicol. 2019, 32, 745–752. DOI: 10.1021/acs.chemrestox.8b00405.
   PubMed Web of Science ®Google Scholar
• Martínez, M.-A.; Rodríguez, J.-L.; Lopez-Torres, B.; Martínez, M.; Martínez-Larrañaga, M.-R.; Maximiliano, J.-E.; Anadón, A.; Ares, I. Use of Human Neuroblastoma SH-SY5Y Cells to Evaluate Glyphosate-Induced Effects on Oxidative Stress, Neuronal Development and Cell Death Signaling Pathways. Environ. Int. 2020, 135, 105414. DOI: 10.1016/j.envint.2019.105414.
   PubMed Web of Science ®Google Scholar
• Harry, G. J.; Billingsley, M.; Bruinink, A.; Campbell, I. L.; Classen, W.; Dorman, D. C.; Galli, C.; Ray, D.; Smith, R. A.; Tilson, H. A. In Vitro Techniques for the Assessment of Neurotoxicity. Environ. Health Perspect. 1998, 106 Suppl 1, 131–158. DOI: 10.2307/3433917.
   PubMed Web of Science ®Google Scholar
• Sonneveld, E.; Riteco, J. A. C.; Jansen, H. J.; Pieterse, B.; Brouwer, A.; Schoonen, W. G.; van der Burg, B. Comparison of in Vitro and in Vivo Screening Models for Androgenic and Estrogenic Activities. Toxicol. Sci. 2006, 89, 173–187. DOI: 10.1093/toxsci/kfj009.
   PubMed Web of Science ®Google Scholar
• Costa, L. G.; Giordano, G.; Guizzetti, M. In Vitro Approaches to Developmental Neurotoxicity. In Reproductive and Developmental Toxicology; Gupta, R.C., Ed.; Academic Press: Amsterdam, 2011; 159–166. DOI: 10.1016/B978-0-12-382032-7.10013-X.
   Google Scholar
• Doke, S. K.; Dhawale, S. C. Alternatives to Animal Testing: A Review. Saudi Pharm. J. 2015, 23, 223–229. DOI: 10.1016/j.jsps.2013.11.002.
   PubMed Web of Science ®Google Scholar
• Wernersson, A.-S.; Carere, M.; Maggi, C.; Tusil, P.; Soldan, P.; James, A.; Sanchez, W.; Dulio, V.; Broeg, K.; Reifferscheid, G.; et al. The European Technical Report on Aquatic Effect-Based Monitoring Tools under the Water Framework Directive. Environ. Sci. Eur. 2015, 27, 7. DOI: 10.1186/s12302-015-0039-4.
   Web of Science ®Google Scholar
• Lu, Q.; Sun, Y.; Ares, I.; Anadón, A.; Martínez, M.; Martínez-Larrañaga, M.-R.; Yuan, Z.; Wang, X.; Martínez, M.-A. Deltamethrin Toxicity: A Review of Oxidative Stress and Metabolism. Environ. Res. 2019, 170, 260–281. DOI: 10.1016/j.envres.2018.12.045.
   PubMed Web of Science ®Google Scholar
• Sule, R. O.; Condon, L.; Gomes, A. V.; Common, A. Feature of Pesticides: Oxidative Stress—the Role of Oxidative Stress in Pesticide-Induced Toxicity. Oxid. Med. Cell Longev. 2022, 2022, 5563759. DOI: 10.1155/2022/5563759.
   PubMed Web of Science ®Google Scholar
• Cox, C.; Surgan, M. Unidentified Inert Ingredients in Pesticides: Implications for Human and Environmental Health. Environ. Health Perspect. 2006, 114, 1803–1806. DOI: 10.1289/ehp.9374.
   PubMed Web of Science ®Google Scholar
• Mesnage, R.; Benbrook, C.; Antoniou, M. N. Insight into the Confusion over Surfactant co-Formulants in Glyphosate-Based Herbicides. Food Chem. Toxicol. 2019, 128, 137–145. DOI: 10.1016/j.fct.2019.03.053.
   PubMed Web of Science ®Google Scholar
• Nagy, K.; Duca, R. C.; Lovas, S.; Creta, M.; Scheepers, P. T. J.; Godderis, L.; Ádám, B. Systematic Review of Comparative Studies Assessing the Toxicity of Pesticide Active Ingredients and Their Product Formulations. Environ. Res. 2020, 181, 108926. DOI: 10.1016/j.envres.2019.108926.
   PubMed Web of Science ®Google Scholar
• Meftaul, I. M.; Venkateswarlu, K.; Dharmarajan, R.; Annamalai, P.; Megharaj, M. Pesticides in the Urban Environment: A Potential Threat That Knocks at the Door. Sci. Total Environ. 2020, 711, 134612. DOI: 10.1016/j.scitotenv.2019.134612.
   PubMed Web of Science ®Google Scholar
• Mesnage, R.; Bernay, B.; Séralini, G.-E. Ethoxylated Adjuvants of Glyphosate-Based Herbicides Are Active Principles of Human Cell Toxicity. Toxicology 2013, 313, 122–128. DOI: 10.1016/j.tox.2012.09.006.
   PubMed Web of Science ®Google Scholar
• Defarge, N.; Takács, E.; Lozano, V. L.; Mesnage, R.; de Vendômois, J. S.; Séralini, G. E.; Székács, A. Co-Formulants in Glyphosate-Based Herbicides Disrupt Aromatase Activity in Human Cells below Toxic Levels. IJERPH 2016, 13, 264. DOI: 10.3390/ijerph13030264.
   Web of Science ®Google Scholar
• Nataraj, B.; Hemalatha, D.; Rangasamy, B.; Maharajan, K.; Ramesh, M. Hepatic Oxidative Stress, Genotoxicity and Histopathological Alteration in Fresh Water Fish Labeo Rohita Exposed to Organophosphorus Pesticide Profenofos. Biocatal. Agric. Biotechnol. 2017, 12, 185–190. DOI: 10.1016/j.bcab.2017.09.006.
   Web of Science ®Google Scholar
• Da Silva Barreto, J.; De Melo Tarouco, F.; Da Rosa, C. E. Chlorothalonil Causes Redox State Change Leading to Oxidative Stress Generation in Danio rerio. Aquat. Toxicol. 2020, 225, 105527. DOI: 10.1016/j.aquatox.2020.105527.
   PubMed Web of Science ®Google Scholar
• Lavarías, S.; García, C.; Crespo, R.; Pedrini, N.; Heras, H. Study of Biochemical Biomarkers in Freshwater Prawn Macrobrachium Borellii (Crustacea: Palaemonidae) Exposed to Organophosphate Fenitrothion. Ecotoxicol. Environ. Saf. 2013, 96, 10–16. DOI: 10.1016/j.ecoenv.2013.05.040.
   PubMed Web of Science ®Google Scholar
• Singh, S.; Tiwari, R. K.; Pandey, R. S. An Insight into the Impact of Triazophos and Deltamethrin Pesticides as Individual and in Combination on Oxidative Stress and Histopathological Alterations in Eudrilus Eugeniae. Chem. Ecol. 2020, 36, 155–173. DOI: 10.1080/02757540.2019.1699536.
   Web of Science ®Google Scholar
• Persch, T. S. P.; da Silva, P. R.; dos Santos, S. H. D.; de Freitas, B. S.; Oliveira, G. T. Changes in Intermediate Metabolism and Oxidative Balance Parameters in Sexually Matured Three-Barbeled Catfishes Exposed to Herbicides from Rice Crops (Roundup®, Primoleo® and Facet®). Environ. Toxicol. Pharmacol. 2018, 58, 170–179. DOI: 10.1016/j.etap.2018.01.004.
   PubMed Web of Science ®Google Scholar
• Stoyanova, S.; Georgieva, E.; Velcheva, I.; Iliev, I.; Vasileva, T.; Bivolarski, V.; Tomov, S.; Nyeste, K.; Antal, L.; Yancheva, V. Multi-Biomarker Assessment in Common Carp (Cyprinus Carpio, Linnaeus 1758) Liver after Acute Chlorpyrifos Exposure. Water 2020, 12, 1837. DOI: 10.3390/w12061837.
   Web of Science ®Google Scholar
• Mosiichuk, N. M.; Husak, V. V.; Maksymiv, I. V.; Hlodan, O. Y.; Storey, J. M.; Storey, K. B.; Lushchak, V. I. Toxicity of Environmental Gesagard to Goldfish May Be Connected with Induction of Low Intensity Oxidative Stress in Concentration- and Tissue-Related Manners. Aquat. Toxicol. 2015, 165, 249–258. DOI: 10.1016/j.aquatox.2015.06.007.
   PubMed Web of Science ®Google Scholar
• Saraiva, A. S.; Sarmento, R. A.; Gravato, C.; Rodrigues, A. C. M.; Campos, D.; Simão, F. C. P.; Soares, A. M. V. M. Strategies of Cellular Energy Allocation to Cope with Paraquat-Induced Oxidative Stress: Chironomids vs Planarians and the Importance of Using Different Species. Sci Total Environ. 2020, 741, 140443. DOI: 10.1016/j.scitotenv.2020.140443.
   PubMed Web of Science ®Google Scholar
• Astiz, M.; de Alaniz, M. J. T.; Marra, C. A. The Impact of Simultaneous Intoxication with Agrochemicals on the Antioxidant Defense System in Rat. Pestic. Biochem. Physiol 2009, 94, 93–99. DOI: 10.1016/j.etap.2009.07.009.
   Web of Science ®Google Scholar
• Marouani, N.; Hallegue, D.; Sakly, M.; Benkhalifa, M.; Ben Rhouma, K.; Tebourbi, O. p,p’-DDT Induces Testicular Oxidative Stress-Induced Apoptosis in Adult Rats. Reprod. Biol. Endocrinol. 2017, 15, 40. DOI: 10.1186/s12958-017-0259-0.
   PubMed Web of Science ®Google Scholar
• Owagboriaye, F. O.; Dedeke, G. A.; Ademolu, K. O.; Olujimi, O. O.; Ashidi, J. S.; Adeyinka, A. A. Reproductive Toxicity of Roundup Herbicide Exposure in Male Albino Rat. Exp. Toxicol. Pathol. 2017, 69, 461–468. DOI: 10.1016/j.etp.2017.04.007.
   PubMedGoogle Scholar
• Ndonwi, E. N.; Atogho-Tiedeu, B.; Lontchi-Yimagou, E.; Shinkafi, T. S.; Nanfa, D.; Balti, E. V.; Indusmita, R.; Mahmood, A.; Katte, J.-C.; Mbanya, A.; et al. Gestational Exposure to Pesticides Induces Oxidative Stress and Lipid Peroxidation in Offspring That Persist at Adult Age in an Animal Model. Toxicol. Res. 2019, 35, 241–248. DOI: 10.5487/TR.2019.35.3.241.
   PubMed Web of Science ®Google Scholar
• Xing, H.; Li, S.; Wang, Z.; Gao, X.; Xu, S.; Wang, X. Oxidative Stress Response and Histopathological Changes Due to Atrazine and Chlorpyrifos Exposure in Common Carp. Pestic. Biochem. Physiol. 2012, 103, 74–80. DOI: 10.1016/j.pestbp.2012.03.007.
   Web of Science ®Google Scholar
• Bouaziz, C.; Graiet, I.; Salah, A.; Ben Salem, I.; Abid, S. Influence of Bifentrin, a Pyrethriod Pesticide, on Human Colorectal HCT-116 Cells Attributed to Alterations in Oxidative Stress Involving Mitochondrial Apoptotic Processes. J. Toxicol. Environ. Health A 2020, 83, 331–340. DOI: 10.1080/15287394.2020.1755756.
   PubMed Web of Science ®Google Scholar
• Lundqvist, J.; Hellman, B.; Oskarsson, A. Fungicide Prochloraz Induces Oxidative Stress and DNA Damage in Vitro. Food Chem. Toxicol. 2016, 91, 36–41. DOI: 10.1016/j.fct.2016.03.002.
   PubMed Web of Science ®Google Scholar
• Wang, X. J.; Hayes, J. D.; Wolf, C. R. Generation of a Stable Antioxidant Response Element-Driven Reporter Gene Cell Line and Its Use to Show Redox-Dependent Activation of Nrf2 by Cancer Chemotherapeutic Agents. Cancer Res. 2006, 66, 10983–10994. DOI: 10.1158/0008-5472.CAN-06-2298.
   PubMed Web of Science ®Google Scholar
• Mozaheb, N.; Arefian, E.; Amoozegar, M. A. Designing a Whole Cell Bioreporter to Show Antioxidant Activities of Agents That Work by Promotion of the KEAP1–NRF2 Signaling Pathway. Sci. Rep. 2019, 9, 3248. DOI: 10.1038/s41598-019-39011-w.
   PubMed Web of Science ®Google Scholar
• Simmons, S. O.; Fan, C. Y.; Yeoman, K.; Wakefield, J.; Ramabhadran, R. Nrf2 Oxidative Stress Induced by Heavy Metals is Cell Type Dependent. Curr. Chem. Genomics 2011, 5, 1–12. DOI: 10.2174/1875397301105010001.
   PubMedGoogle Scholar
• De Freitas Silva, M.; Pruccoli, L.; Morroni, F.; Sita, G.; Seghetti, F.; Viegas, C.; Tarozzi, A. The Keap1/Nrf2-ARE Pathway as a Pharmacological Target for Chalcones. Molecules 2018, 23, 1803. DOI: 10.3390/molecules23071803.
   PubMed Web of Science ®Google Scholar
• Escher, B. I.; Dutt, M.; Maylin, E.; Tang, J. Y. M.; Toze, S.; Wolf, C. R.; Lang, M. Water Quality Assessment Using the AREc32 Reporter Gene Assay Indicative of the Oxidative Stress Response Pathway. J. Environ. Monit. 2012, 14, 2877–2885. DOI: 10.1039/c2em30506b.
   PubMedGoogle Scholar
• Van der Linden, S. C.; von Bergh, A. R. M.; van Vught-Lussenburg, B. M. A.; Jonker, L. R. A.; Teunis, M.; Krul, C. A. M.; van der Burg, B. Development of a Panel of High-Throughput Reporter-Gene Assays to Detect Genotoxicity and Oxidative Stress. Mutat. Res. Genet. Toxicol. Environ. Mutagen. 2014, 760, 23–32. DOI: 10.1016/j.mrgentox.2013.09.009.
   PubMed Web of Science ®Google Scholar
• Wang, S.; Zhang, H.; Zheng, W.; Wang, X.; Andersen, M. E.; Pi, J.; He, G.; Qu, W. Organic Extract Contaminants from Drinking Water Activate Nrf2-Mediated Antioxidant Response in a Human Cell Line. Environ. Sci. Technol. 2013, 47, 4768–4777. DOI: 10.1021/es305133k.
   PubMed Web of Science ®Google Scholar
• Oskarsson, A.; Kjerstine, A.; Mandava, G.; Johannisson, A.; Holmes, A.; Tröger, R.; Lundqvist, J. Assessment of Source and Treated Water Quality in Seven Drinking Water Treatment Plants by in Vitro Bioassays – Oxidative Stress and Antiandrogenic Effects after Artificial Infiltration. Sci. Total Environ. 2021, 758, 144001. DOI: 10.1016/j.scitotenv.2020.144001.
   PubMed Web of Science ®Google Scholar
• Lungu-Mitea, S.; Oskarsson, A.; Lundqvist, J. Development of an Oxidative Stress in Vitro Assay in Zebrafish (Danio rerio) Cell Lines. Sci. Rep. 2018, 8, 12380. DOI: 10.1038/s41598-018-30880-1.
   PubMed Web of Science ®Google Scholar
• Brack, W.; Aissa, S. A.; Backhaus, T.; Dulio, V.; Escher, B. I.; Faust, M.; Hilscherova, K.; Hollender, J.; Hollert, H.; Müller, C.; et al. Effect‑Based Methods Are Key: The European Collaborative Project SOLUTIONS Recommends Integrating Effect‑Based Methods for Diagnosis and Monitoring of Water Quality. Environ. Sci. Eur. 2019, 31, 4–9. DOI: 10.1186/s12302-019-0192-2.
   Web of Science ®Google Scholar
• Tang, F. H. M.; Lenzen, M.; McBratney, A.; Maggi, F. Risk of Pesticide Pollution at the Global Scale. Nat. Geosci. 2021, 14, 206–210. DOI: 10.1038/s41561-021-00712-5.
   Web of Science ®Google Scholar
• Kronberg, M. F.; Clavijo, A.; Moya, A.; Rossen, A.; Calvo, D.; Pagano, E.; Munarriz, E. Glyphosate-Based Herbicides Modulate Oxidative Stress Response in the Nematode Caenorhabditis elegans. Comp. Biochem. Physiol. C Toxicol. Pharmacol. 2018, 214, 1–8. DOI: 10.1016/j.cbpc.2018.08.002.
   PubMed Web of Science ®Google Scholar
• Paravani, E. V.; Simoniello, M. F.; Poletta, G. L.; Zolessi, F. R.; Casco, V. H. Cypermethrin: Oxidative Stress and Genotoxicity in Retinal Cells of the Adult Zebrafish. Mutat. Res. Genet. Toxicol. Environ. Mutagen. 2018, 826, 25–32. DOI: 10.1016/j.mrgentox.2017.12.010.
   PubMed Web of Science ®Google Scholar
• Sotomayor, V.; Chiriotto, T. S.; Pechen, A. M.; Venturino, A. Biochemical Biomarkers of Sublethal Effects in Rhinella Arenarum Late Gastrula Exposed to the Organophosphate Chlorpyrifos. Pest. Biochem. Physiol. 2015, 119, 48–53. DOI: 10.1016/j.pestbp.2015.02.006.
   PubMed Web of Science ®Google Scholar
• De Moura, F. R.; Brentegani, K. R.; Gemelli, A.; Sinhorin, A. P.; Sinhorin, V. D. G. Oxidative Stress in the Hybrid Fish Jundiara (Leiarius Marmoratus × Pseudoplatystoma Reticulatum) Exposed to Roundup Original®. Chemosphere 2017, 185, 445–451. DOI: 10.1016/j.chemosphere.2017.07.030.
   PubMed Web of Science ®Google Scholar
• Saggioro, E. M.; do Espírito Santo, D. G.; Sales Júnior, S. F.; Hauser-Davis, R. A.; Correia, F. V. Lethal and Sublethal Effects of Acetamiprid on Eisenia Andrei: Behavior, Reproduction, Cytotoxicity and Oxidative Stress. Ecotoxicol. Environ. Saf. 2019, 183, 109572. DOI: 10.1016/j.ecoenv.2019.109572.
   PubMed Web of Science ®Google Scholar
• Sinhorin, V. D. G.; Sinhorin, A. P.; dos Santos Teixeira, J. M.; Miléski, K. M. L.; Hansen, P. C.; Moreira, P. S. A.; Kawashita, N. H.; Baviera, A. M.; Loro, V. L. Effects of the Acute Exposition to Glyphosate-Based Herbicide on Oxidative Stress Parameters and Antioxidant Responses in a Hybrid Amazon Fish Surubim (Pseudoplatystoma sp). Ecotoxicol. Environ. Saf. 2014, 106, 181–187. DOI: 10.1016/j.ecoenv.2014.04.040.
   PubMed Web of Science ®Google Scholar
• Ma, J.; Zhu, J.; Wang, W.; Ruan, P.; Rajeshkumar, S.; Li, X. Biochemical and Molecular Impacts of Glyphosate-Based Herbicide on the Gills of Common Carp. Environ. Pollut. 2019, 252, 1288–1300. DOI: 10.1016/j.envpol.2019.06.040.
   PubMed Web of Science ®Google Scholar
• Mao, L.; Jia, W.; Zhang, L.; Zhang, Y.; Zhu, L.; Sial, M. U.; Jiang, H. Embryonic Development and Oxidative Stress Effects in the Larvae and Adult Fish Livers of Zebrafish (Danio rerio) Exposed to the Strobilurin Fungicides, Kresoxim-Methyl and Pyraclostrobin. Sci. Total Environ. 2020, 729, 139031. DOI: 10.1016/j.scitotenv.2020.139031.
   PubMed Web of Science ®Google Scholar
• Qi, S.; Wang, C.; Chen, X.; Qin, Z.; Li, X.; Wang, C. Toxicity Assessments with Daphnia Magna of Guadipyr, a New Neonicotinoid Insecticide and Studies of Its Effect on Acetylcholinesterase (AChE), glutathione-S-Transferase (GST), Catalase (CAT) and Chitobiase Activities. Ecotoxicol. Environ. Saf. 2013, 98, 339–344. DOI: 10.1016/j.ecoenv.2013.09.013.
   PubMed Web of Science ®Google Scholar
• Wang, G.; Xiong, D.; Wu, M.; Wang, L.; Yang, J. Induction of Time- and Dose-Dependent Oxidative Stress of Triazophos to Brain and Liver in Zebrafish (Danio rerio). Comp. Biochem. Physiol. C Toxicol. Pharmacol. 2020, 228, 108640. DOI: 10.1016/j.cbpc.2019.108640.
   PubMed Web of Science ®Google Scholar
• Wang, J.; Wang, J.; Wang, G.; Zhu, L.; Wang, J. DNA Damage and Oxidative Stress Induced by Imidacloprid Exposure in the Earthworm Eisenia Fetida. Chemosphere 2016, 144, 510–517. DOI: 10.1016/j.chemosphere.2015.09.004.
   PubMed Web of Science ®Google Scholar
• Yan, S.; Meng, Z.; Tian, S.; Teng, M.; Yan, J.; Jia, M.; Li, R.; Zhou, Z.; Zhu, W. Neonicotinoid Insecticides Exposure Cause Amino Acid Metabolism Disorders, Lipid Accumulation and Oxidative Stress in ICR Mice. Chemosphere 2020, 246, 125661. DOI: 10.1016/j.chemosphere.2019.125661.
   PubMed Web of Science ®Google Scholar
• Kopjar, N.; Žunec, S.; Mendaš, G.; Micek, V.; Kašuba, V.; Mikolić, A.; Lovaković, B. T.; Milić, M.; Pavičić, I.; Čermak, A. M. M.; et al. Evaluation of Chlorpyrifos Toxicity through a 28-Day Study: Cholinesterase Activity, Oxidative Stress Responses, Parent Compound/Metabolite Levels, and Primary DNA Damage in Blood and Brain Tissue of Adult Male Wistar Rats. Chem. Biol. Interact. 2018, 279, 51–63. DOI: 10.1016/j.cbi.2017.10.029.
   PubMed Web of Science ®Google Scholar
• Tariba Lovaković, B.; Pizent, A.; Kašuba, V.; Kopjar, N.; Micek, V.; Mendaš, G.; Dvoršćak, M.; Mikolić, A.; Milić, M.; Žunec, S.; et al. Effects of Sub-Chronic Exposure to Terbuthylazine on DNA Damage, Oxidative Stress and Parent Compound/Metabolite Levels in Adult Male Rats. Food Chem. Toxicol. 2017, 108, 3–103. DOI: 10.1016/j.fct.2017.07.046.
   Web of Science ®Google Scholar
• Blahová, J.; Plhalová, L.; Hostovský, M.; Divišová, L.; Dobšíková, R.; Mikulíková, I.; Štěpánová, S.; Svobodová, Z. Oxidative Stress Responses in Zebrafish Danio rerio after Subchronic Exposure to Atrazine. Food Chem. Toxicol. 2013, 61, 82–85. DOI: 10.1016/j.fct.2013.02.041.
   PubMed Web of Science ®Google Scholar
• Stara, A.; Kristan, J.; Zuskova, E.; Velisek, J. Effect of Chronic Exposure to Prometryne on Oxidative Stress and Antioxidant Response in Common Carp (Cyprinus Carpio L.). Pest. Biochem. Physiol. 2013, 105, 18–23. DOI: 10.1016/j.pestbp.2012.11.002.
   PubMed Web of Science ®Google Scholar
• Abu Zeid, E. H.; Alam, R. T. M.; Ali, S. A.; Hendawi, M. Y. Dose-Related Impacts of Imidacloprid Oral Intoxication on Brain and Liver of Rock Pigeon (Columba Livia Domestica), Residues Analysis in Different Organs. Ecotoxicol. Environ. Saf. 2019, 167, 60–68. DOI: 10.1016/j.ecoenv.2018.09.121.
   PubMed Web of Science ®Google Scholar
• Amin, K. A.; Hashem, K. S. Deltamethrin-Induced Oxidative Stress and Biochemical Changes in Tissues and Blood of Catfish (Clarias Gariepinus): Antioxidant Defense and Role of Alpha-Tocopherol. BMC Vet. Res. 2012, 8, 45. DOI: 10.1186/1746-6148-8-45.
   PubMed Web of Science ®Google Scholar
• Héritier, L.; Duval, D.; Galinier, R.; Meistertzheim, A. L.; Verneau, O. Oxidative Stress Induced by Glyphosate-Based Herbicide on Freshwater Turtles. Environ. Toxicol. Chem. 2017, 36, 3343–3350. DOI: 10.1002/etc.3916.
   PubMed Web of Science ®Google Scholar
• Contardo-Jara, V.; Gessner, M. O. Uptake and Physiological Effects of the Neonicotinoid Imidacloprid and Its Commercial Formulation Confidor® in a Widespread Freshwater Oligochaete. Environ. Pollut. 2020, 264, 114793. DOI: 10.1016/j.envpol.2020.114793.
   PubMed Web of Science ®Google Scholar
• Bano, F.; Mohanty, B. Thyroid Disrupting Pesticides Mancozeb and Fipronil in Mixture Caused Oxidative Damage and Genotoxicity in Lymphoid Organs of Mice. Environ. Toxicol. Pharmacol. 2020, 79, 103408. DOI: 10.1016/j.etap.2020.103408.
   PubMed Web of Science ®Google Scholar
• Rodríguez-Fuentes, G.; Rubio-Escalante, F. J.; Noreña-Barroso, E.; Escalante-Herrera, K. S.; Schlenk, D. Impacts of Oxidative Stress on Acetylcholinesterase Transcription, and Activity in Embryos of Zebrafish (Danio rerio) following Chlorpyrifos Exposure. Comp Biochem Physiol C Toxicol Pharmacol 2015, 172-173, 19–25. DOI: 10.1016/j.cbpc.2015.04.003.
   PubMed Web of Science ®Google Scholar
• Bali, Y. A.; Kaikai, N.-E.; Ba-M’hamed, S.; Bennis, M. Learning and Memory Impairments Associated to Acetylcholinesterase Inhibition and Oxidative Stress following Glyphosate-Based Herbicide Exposure in Mice. Toxicology 2019, 415, 18–25. DOI: 10.1016/j.tox.2019.01.010.
   PubMed Web of Science ®Google Scholar
• Jijie, R.; Solcan, G.; Nicoara, M.; Micu, D.; Strungaru, S.-A. Antagonistic Effects in Zebrafish (Danio rerio) Behavior and Oxidative Stress Induced by Toxic Metals and Deltamethrin Acute Exposure. Sci. Total Environ. 2020, 698, 134299. DOI: 10.1016/j.scitotenv.2019.134299.
   PubMed Web of Science ®Google Scholar
• Martínez, M.-A.; Ares, I.; Rodríguez, J. L.; Martínez, M.; Roura-Martínez, D.; Castellano, V.; Lopez-Torres, B.; Martínez-Larrañaga, M.; R.; Anadón, A. Pyrethroid Insecticide Lambda-Cyhalothrin Induces Hepatic Cytochrome P450 Enzymes, Oxidative Stress and Apoptosis in Rats. Sci. Total Environ. 2018, 631-632, 1371–1382. DOI: 10.1016/j.scitotenv.2018.03.030.
   PubMed Web of Science ®Google Scholar
• Gerber, R.; Smit, N. J.; van Vuren, J. H. J.; Ikenaka, Y.; Wepener, V. Biomarkers in Tigerfish (Hydrocynus Vittatus) as Indicators of Metal and Organic Pollution in Ecologically Sensitive Subtropical Rivers. Ecotoxicol. Environ. Saf. 2018, 157, 307–317. DOI: 10.1016/j.ecoenv.2018.03.091.
   PubMed Web of Science ®Google Scholar
• Jansen van Rensburg, G.; Bervoets, L.; Smit, N. J.; Wepener, V.; van Vuren, J. Biomarker Responses in the Freshwater Shrimp Caridina Nilotica as Indicators of Persistent Pollutant Exposure. Bull. Environ. Contam. Toxicol. 2020, 104, 193–199. DOI: 10.1007/s00128-019-02773-0.
   PubMed Web of Science ®Google Scholar
• Volschenk, C. M.; Ikenaka, Y.; Yohannes, Y. B.; Nakayama, S. M.; Ishizuka, M.; Smit, E.; van Vuren, J. H. J.; Greenfield, R. Baseline Bio-Accumulation Concentrations and Resulting Oxidative Stress in Synodontis Zambezensis after an Acute Laboratory Exposure to 4,4′-DDT. Pest. Biochem. Physiol. 2019, 156, 44–55. DOI: 10.1016/j.pestbp.2019.02.005.
   PubMed Web of Science ®Google Scholar
• Yoon, D. S.; Park, J. C.; Park, H. G.; Lee, J. S.; Han, J. Effects of Atrazine on Life Parameters, Oxidative Stress, and Ecdysteroid Biosynthetic Pathway in the Marine Copepod Tigriopus Japonicus. Aquat. Toxicol. 2019, 213, 105213. DOI: 10.1016/j.aquatox.2019.05.015.
   PubMed Web of Science ®Google Scholar
• Akbel, E.; Arslan-Acaroz, D.; Demirel, H. H.; Kucukkurt, I.; Ince, S. The Subchronic Exposure to Malathion, an Organophosphate Pesticide, Causes Lipid Peroxidation, Oxidative Stress, and Tissue Damage in Rats: The Protective Role of Resveratrol. Toxicol. Res. (Camb) 2018, 7, 503–512. DOI: 10.1039/c8tx00030a.
   PubMed Web of Science ®Google Scholar
• Pala, A. The Effect of a Glyphosate-Based Herbicide on Acetylcholinesterase (AChE) Activity, Oxidative Stress, and Antioxidant Status in Freshwater Amphipod: Gammarus Pulex (Crustacean). Environ. Sci. Pollut. Res. Int. 2019, 26, 36869–36877. DOI: 10.1007/s11356-019-06804-5.
   PubMed Web of Science ®Google Scholar
• Kubrak, O. I.; Atamaniuk, T. M.; Husak, V. V.; Drohomyretska, I. Z.; Storey, J. M.; Storey, K. B.; Lushchak, V. I. Oxidative Stress Responses in Blood and Gills of Carassius auratus Exposed to the Mancozeb-Containing Carbamate Fungicide Tattoo. Ecotoxicol. Environ. Saf. 2012, 85, 37–43. DOI: 10.1016/j.ecoenv.2012.08.021.
   PubMed Web of Science ®Google Scholar
• Andrioli, N. B.; Chaufan, G. Dose-Independent Genotoxic Response in A549 Cell Line Exposed to Fungicide Iprodione. Arch. Toxicol. 2021, 95, 1071–1079. DOI: 10.1007/s00204-020-02954-5.
   PubMed Web of Science ®Google Scholar
• Chaufan, G.; Coalova, I.; Ríos de Molina, M. D. C. Del Carmen Ríos de Molina, M. Glyphosate Commercial Formulation Causes Cytotoxicity, Oxidative Effects, and Apoptosis on Human Cells. Int. J. Toxicol. 2014, 33, 29–38. DOI: 10.1177/1091581813517906.
   PubMed Web of Science ®Google Scholar
• Gomez, S. D.; Bustos, P. S.; Sánchez, V. G.; Ortega, M. G.; Guiñazú, N. Trophoblast Toxicity of the Neonicotinoid Insecticide Acetamiprid and an Acetamiprid-Based Formulation. Toxicology 2020, 431, 152363. DOI: 10.1016/j.tox.2020.152363.
   PubMed Web of Science ®Google Scholar
• Weis, G. C. C.; Assmann, C. E.; Mostardeiro, V. B.; de Oliveira Alves, A.; da Rosa, J. R.; Pillat, M. M.; Melazzo de Andrade, C.; Schetinger, M. R. C.; Morsch, V. M. M.; da Cruz, I. B. M.; Costabeber, I. H. Chlorpyrifos Pesticide Promotes Oxidative Stress and Increases Inflammatory States in BV-2 Microglial Cells: A Role in Neuroinflammation. Chemosphere 2021, 278, 130417. DOI: 10.1016/j.chemosphere.2021.130417.
   PubMed Web of Science ®Google Scholar
• Tao, H.; Bao, Z.; Jin, C.; Miao, W.; Fu, Z.; Jin, Y. Toxic Effects and Mechanisms of Three Commonly Used Fungicides on the Human Colon Adenocarcinoma Cell Line Caco-2. Environ. Pollut. 2020, 263, 114660. DOI: 10.1016/j.envpol.2020.114660.
   Web of Science ®Google Scholar
• Kašuba, V.; Milić, M.; Rozgaj, R.; Kopjar, N.; Mladinić, M.; Žunec, S.; Vrdoljak, A. L.; Pavičić, I.; Čermak, A. M. M.; Pizent, A.; et al. Effects of Low Doses of Glyphosate on DNA Damage, Cell Proliferation and Oxidative Stress in the HepG2 Cell Line. Environ. Sci. Pollut. Res. Int. 2017, 24, 19267–19281. DOI: 10.1007/s11356-017-9438-y.
   PubMed Web of Science ®Google Scholar
• Želježić, D.; Mladinić, M.; Žunec, S.; Lucić Vrdoljak, A.; Kašuba, V.; Tariba, B.; Živković, T.; Marjanović, A. M.; Pavičić, I.; Milić, M.; et al. Cytotoxic, Genotoxic and Biochemical Markers of Insecticide Toxicity Evaluated in Human Peripheral Blood Lymphocytes and an HepG2 Cell Line. Food Chem. Toxicol. 2016, 96, 90–106. DOI: 10.1016/j.fct.2016.07.036.
   PubMed Web of Science ®Google Scholar
• Žunec, S.; Kašuba, V.; Pavičić, I.; Marjanović, A. M.; Tariba, B.; Milić, M.; Kopjar, N.; Pizent, A.; Vrdoljak, A. L.; Rozgaj, R.; Želježić, D. Assessment of Oxidative Stress Responses and the Cytotoxic and Genotoxic Potential of the Herbicide Tembotrione in HepG2 Cells. Food Chem. Toxicol. 2016, 94, 64–74. DOI: 10.1016/j.fct.2016.05.019.
   PubMed Web of Science ®Google Scholar
• Gargouri, B.; Boukholda, K.; Kumar, A.; Benazzouz, A.; Fetoui, H.; Fiebich, B. L.; Bouchard, M. Bifenthrin Insecticide Promotes Oxidative Stress and Increases Inflammatory Mediators in Human Neuroblastoma Cells through NF-kappaB Pathway. Toxicol. In Vitro 2020, 65, 104792. DOI: 10.1016/j.tiv.2020.104792.
   PubMed Web of Science ®Google Scholar
• Al-Sarar, A. S.; Bayoumi, A. E.; Hussein, H. I.; Abobakr, Y. Cytotoxic Effects of Acephate, Ethoprophos, and Monocrotophos in CHO-K1 Cells. CYTA – J. Food 2015, 13, 427–433. DOI: 10.1080/19476337.2014.996916.
   Web of Science ®Google Scholar
• Moyano, P.; García, J. M.; García, J.; Pelayo, A.; Muñoz-Calero, P.; Frejo, M. T.; Anadon, M. J.; Naval, M. V.; Flores, A.; Mirat, V. A.; Del Pino, J. Chlorpyrifos Induces Cell Proliferation in MCF-7 and MDA-MB-231 Cells, through Cholinergic and Wnt/β-Catenin Signaling Disruption, AChE-R Upregulation and Oxidative Stress Generation after Single and Repeated Treatment. Food Chem. Toxicol. 2021, 152, 112241. DOI: 10.1016/j.fct.2021.112241.
   PubMed Web of Science ®Google Scholar
• Romero, A.; Ramos, E.; Castellano, V.; Martínez, M. A.; Ares, I.; Martínez, M.; Martínez-Larrañaga, M. R.; Anadón, A. Cytotoxicity Induced by Deltamethrin and Its Metabolites in SH-SY5Y Cells Can Be Differentially Prevented by Selected Antioxidants. Toxicol. In Vitro 2012, 26, 823–830. DOI: 10.1016/j.tiv.2012.05.004.
   PubMed Web of Science ®Google Scholar
• Boussabbeh, M.; Ben Salem, I.; Hamdi, M.; Ben Fradj, S.; Abid-Essefi, S.; Bacha, H. Diazinon, an Organophosphate Pesticide, Induces Oxidative Stress and Genotoxicity in Cells Deriving from Large Intestine. Environ. Sci. Pollut. Res. Int. 2016, 23, 2882–2889. DOI: 10.1007/s11356-015-5519-y.
   PubMed Web of Science ®Google Scholar
• Kara, M.; Oztas, E.; Ramazanoğulları, R.; Kouretas, D.; Nepka, C.; Tsatsakis, A. M.; Veskoukis, A. S. Benomyl, a Benzimidazole Fungicide, Induces Oxidative Stress and Apoptosis in Neural Cells. Toxicol. Rep. 2020, 7, 501–509. DOI: 10.1016/j.toxrep.2020.04.001.
   PubMed Web of Science ®Google Scholar