REFERENCES
- Agassandian M., Mathur S. N., Zhou J., Field F. J., Mallampalli R. K. Oxysterols trigger ABCA1-mediated basolateral surfactant efflux. Am. J. Respir. Cell. Mol. Biol. 2004; 31: 227–233, [PUBMED], [INFOTRIEVE], [CSA]
- Al-Khalili L., Cartee G. D., Krook A. RNA interference-mediated reduction in GLUT1 inhibits serum-induced glucose transport in primary human skeletal muscle cells. Biochem. Biophys. Res. Commun. 2003; 307: 127–132, [PUBMED], [INFOTRIEVE], [CROSSREF], [CSA]
- Ambudkar S. V., Kimchi-Sarfaty C., Sauna Z. E., Gottesman M. M. P-glycoprotein: from genomics to mechanism. Oncogene 2003; 22: 7468–7485, [PUBMED], [INFOTRIEVE], [CROSSREF], [CSA]
- An D. S., Xie Y., Mao S. H., Morizono K., Kung S. K., Chen I. S. Efficient lentiviral vectors for short hairpin RNA delivery into human cells. Hum. Gene. Ther. 2003; 14: 1207–1212, [PUBMED], [INFOTRIEVE], [CROSSREF], [CSA]
- Aoki Y., Cioca D. P., Oidaira H., Kamiya J., Kiyosawa K. RNA interference may be more potent than antisense RNA in human cancer cell lines. Clin. Exp. Pharmacol. Physiol. 2003; 30: 96–102, [PUBMED], [INFOTRIEVE], [CROSSREF], [CSA]
- Ayrton A., Morgan P. Role of transport proteins in drug absorption, distribution and excretion. Xenobiotica 2001; 31: 469–497, [PUBMED], [INFOTRIEVE], [CROSSREF], [CSA]
- Bain J. R., Schisler J. C., Takeuchi K., Newgard C. B., Becker T. C. An adenovirus vector for efficient RNA interference-mediated suppression of target genes in insulinoma cells and pancreatic islets of langerhans. Diabetes 2004; 53: 2190–2194, [PUBMED], [INFOTRIEVE], [CSA]
- Balamurugan K., Ortiz A., Said H. M. Biotin uptake by human intestinal and liver epithelial cells: role of the SMVT system. Am. J. Physiol. Gastrointest. Liver Physiol. 2003; 285: G73–77, [PUBMED], [INFOTRIEVE], [CSA]
- Caplen N. J., Parrish S., Imani F., Fire A., Morgan R. A. Specific inhibition of gene expression by small double-stranded RNAs in invertebrate and vertebrate systems. Proc. Natl. Acad. Sci. USA. 2001; 98: 9742–9747, [PUBMED], [INFOTRIEVE], [CROSSREF], [CSA]
- Celius T., Garberg P., Lundgren B. Stable suppression of MDR1 gene expression and function by RNAi in Caco-2 cells. Biochem. Biophys. Res. Commun. 2004; 324: 365–371, [PUBMED], [INFOTRIEVE], [CROSSREF], [CSA]
- Chang H. S., Lin C. H., Chen Y. C., Yu W. C. Using siRNA technique to generate transgenic animals with spatiotemporal and conditional gene knockdown. Am. J. Pathol. 2004; 165: 1535–1541, [PUBMED], [INFOTRIEVE], [CSA]
- Christiansen-Weber T. A., Voland J. R., Wu Y., Ngo K., Roland B. L., Nguyen S., Peterson P. A., Fung-Leung W. P. Functional loss of ABCA1 in mice causes severe placental malformation, aberrant lipid distribution, and kidney glomerulonephritis as well as high-density lipoprotein cholesterol deficiency. Am. J. Pathol. 2000; 157: 1017–1029, [PUBMED], [INFOTRIEVE], [CSA]
- Dykxhoorn D. M., Novina C. D., Sharp P. A. Killing the messenger: short RNAs that silence gene expression. Nat. Rev. Mol. Cell. Biol. 2003; 4: 457–467, [PUBMED], [INFOTRIEVE], [CROSSREF], [CSA]
- Editorial NCB. Whither RNAi?. Nat. Cell. Biol. 2003; 5: 489–490, [CROSSREF], [CSA]
- Elbashir S. M., Harborth J., Lendeckel W., Yalcin A., Weber K., Tuschl T. Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells. Nature 2001a; 411: 494–498, [PUBMED], [INFOTRIEVE], [CROSSREF], [CSA]
- Elbashir S. M., Harborth J., Weber K., Tuschl T. Analysis of gene function in somatic mammalian cells using small interfering RNAs. Methods 2002; 26: 199–213, [PUBMED], [INFOTRIEVE], [CROSSREF], [CSA]
- Elbashir S. M., Lendeckel W., Tuschl T. RNA interference is mediated by 21- and 22-nucleotide RNAs. Genes Dev. 2001b; 15: 188–200, [PUBMED], [INFOTRIEVE], [CROSSREF], [CSA]
- Fei Y. J., Liu J. C., Inoue K., Zhuang L., Miyake K., Miyauchi S., Ganapathy V. Relevance of NAC-2, an Na+coupled citrate transporter, to life span, body size and fat content in Caenorhabditis elegans. Biochem. J. 2004; 379: 191–198, [PUBMED], [INFOTRIEVE], [CROSSREF], [CSA]
- Fire A., Xu S., Montgomery M. K., Kostas S. A., Driver S. E., Mello C. C. Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans. Nature 1998; 391: 806–811, [PUBMED], [INFOTRIEVE], [CROSSREF], [CSA]
- Fukumoto H., Deng A., Irizarry M. C., Fitzgerald M. L., Rebeck G. W. Induction of the cholesterol transporter ABCA1 in central nervous system cells by liver X receptor agonists increases secreted Abeta levels. J. Biol. Chem. 2002; 277: 48508–48513, [PUBMED], [INFOTRIEVE], [CROSSREF], [CSA]
- Gottesman M. M. Mechanisms of cancer drug resistance. Annu. Rev. Med. 2002; 53: 615–627, [PUBMED], [INFOTRIEVE], [CROSSREF], [CSA]
- Gottesman M. M., Fojo T., Bates S. E. Multidrug resistance in cancer: role of ATP-dependent transporters. Nat. Rev. Cancer. 2002; 2: 48–58, [PUBMED], [INFOTRIEVE], [CROSSREF], [CSA]
- Gresch O., Engel F. B., Nesic D., Tran T. T., England H. M., Hickman E. S., Korner I., Gan L., Chen S., Castro-Obregon S., Hammermann R., Wolf J., Muller-Hartmann H., Nix M., Siebenkotten G., Kraus G., Lun K. New non-viral method for gene transfer into primary cells. Methods 2004; 33: 151–163, [PUBMED], [INFOTRIEVE], [CROSSREF], [CSA]
- Hadjeri M., Barbier M., Ronot X., Mariotte A. M., Boumendjel A., Boutonnat J. Modulation of P-glycoprotein-mediated multidrug resistance by flavonoid derivatives and analogues. J. Med. Chem. 2003; 46: 2125–2131, [PUBMED], [INFOTRIEVE], [CROSSREF], [CSA]
- Hannon G. J. RNA interference. Nature 2002; 418: 244–251, [PUBMED], [INFOTRIEVE], [CROSSREF], [CSA]
- Hirano M., Maeda K., Shitara Y., Sugiyama Y. Contribution of OATP2 (OATP1B1) and OATP8 (OATP1B3) to the hepatic uptake of pitavastatin in humans. J. Pharmacol. Exp. Ther. 2004; 311: 139–146, [PUBMED], [INFOTRIEVE], [CROSSREF], [CSA]
- Hoffmaster K. A., Turncliff R. Z., LeCluyse E. L., Kim R. B., Meier P. J., Brouwer K. L. P-glycoprotein expression, localization, and function in sandwich-cultured primary rat and human hepatocytes: relevance to the hepatobiliary disposition of a model opioid peptide. Pharm. Res. 2004a; 21: 1294–1302, [PUBMED], [INFOTRIEVE], [CROSSREF], [CSA]
- Hoffmaster K. A., Zamek-Gliszczynski M. J., Pollack G. M., Brouwer K. L. Hepatobiliary disposition of the metabolically stable opioid peptide [D-penicillamine2,5]enkephalin (DPDPE): pharmacokinetic consequences of the interplay between multiple transport systems. J. Pharmacol. Exp. Ther. 2004b, [CSA]
- Hough S. R., Wiederholt K. A., Burrier A. C., Woolf T. M., Taylor M. F. Why RNAi makes sense. Nat. Biotechnol. 2003; 21: 731–732, [PUBMED], [INFOTRIEVE], [CROSSREF], [CSA]
- Huang Y., Anderle P., Bussey K. J., Barbacioru C., Shankavaram U., Dai Z., Reinhold W. C., Papp A., Weinstein J. N., Sadee W. Membrane transporters and channels: role of the transportome in cancer chemosensitivity and chemoresistance. Cancer Res. 2004; 64: 4294–4301, [PUBMED], [INFOTRIEVE], [CROSSREF], [CSA]
- Jackson A. L., Bartz S. R., Schelter J., Kobayashi S. V., Burchard J., Mao M., Li B., Cavet G., Linsley P. S. Expression profiling reveals off-target gene regulation by RNAi. Nat. Biotechnol. 2003; 21: 635–637, [PUBMED], [INFOTRIEVE], [CROSSREF], [CSA]
- Jiang G., Zhuang L., Miyauchi S., Miyake K., Fei Y. J., Ganapathy V. A Na+/Cl-coupled GABA transporter, GAT-1, from caenorhabditis elegans: structural and functional features, specific expression in GABAergic neurons, and involvement in muscle function. J. Biol. Chem. 2004; 280, [INFOTRIEVE], [CSA]
- Jordi P., Gottesman M. M., Aran J. M. A MDR-EGFP gene fusion allows for direct cellular localization, function and stability assessment of P-glycoprotein. Current Drug Delivery 2004; 1: 43–56, [CROSSREF], [CSA]
- Kahr H., Schindl R., Fritsch R., Heinze B., Hofbauer M., Hack M. E., Mortelmaier M. A., Groschner K., Peng J. B., Takanaga H., Hediger M. A., Romanin C. CaT1 knock-down strategies fail to affect CRAC channels in mucosal-type mast cells. J. Physiol. 2004; 557: 121–132, [PUBMED], [INFOTRIEVE], [CROSSREF], [CSA]
- Kim R. B. Drugs as P-glycoprotein substrates, inhibitors, and inducers. Drug Metab. Rev. 2002; 34: 47–54, [PUBMED], [INFOTRIEVE], [CROSSREF], [CSA]
- Kivipelto M., Helkala E. L., Laakso M. P., Hanninen T., Hallikainen M., Alhainen K., Soininen H., Tuomilehto J., Nissinen A. Midlife vascular risk factors and Alzheimer’s disease in later life: longitudinal, population based study. BMJ 2001; 322: 1447–1451, [PUBMED], [INFOTRIEVE], [CROSSREF], [CSA]
- Lage H. ABC-transporters: implications on drug resistance from microorganisms to human cancers. Int. J. Antimicrob. Agents. 2003; 22: 188–199, [PUBMED], [INFOTRIEVE], [CROSSREF], [CSA]
- Lam W., Chen C., Ruan S., Leung C. H., Cheng Y. C. Expression of deoxynucleotide carrier is not associated with the mitochondrial DNA depletion caused by anti-HIV dideoxynucleoside analogs and mitochondrial dNTP uptake. Mol. Pharmacol. 2004; 67, [CROSSREF], [CSA]
- Lee J. T., Jr., Steelman L. S., McCubrey J. A. Phosphatidylinositol 3’-kinase activation leads to multidrug resistance protein-1 expression and subsequent chemoresistance in advanced prostate cancer cells. Cancer Res. 2004; 64: 8397–8404, [PUBMED], [INFOTRIEVE], [CROSSREF], [CSA]
- Lewis D. L., Hagstrom J. E., Loomis A. G., Wolff J. A., Herweijer H. Efficient delivery of siRNA for inhibition of gene expression in postnatal mice. Nat. Genet. 2002; 32: 107–108, [PUBMED], [INFOTRIEVE], [CROSSREF], [CSA]
- Lin J. H. Drug-drug interaction mediated by inhibition and induction of P-glycoprotein. Adv. Drug Deliv. Rev. 2003; 55: 53–81, [PUBMED], [INFOTRIEVE], [CROSSREF], [CSA]
- Lin J. H., Yamazaki M. Role of P-glycoprotein in pharmacokinetics: clinical implications. Clin. Pharmacokinet. 2003; 42: 59–98, [PUBMED], [INFOTRIEVE], [CSA]
- Liu S., Stromberg A., Tai H. H., Moscow J. A. Thiamine transporter gene expression and exogenous thiamine modulate the expression of genes involved in drug and prostaglandin metabolism in breast cancer cells. Mol. Cancer Res. 2004; 2: 477–487, [PUBMED], [INFOTRIEVE], [CSA]
- Liu X., LeCluyse E. L., Brouwer K. R., Gan L. S., Lemasters J. J., Stieger B., Meier P. J., Brouwer K. L. Biliary excretion in primary rat hepatocytes cultured in a collagen-sandwich configuration. Am. J. Physiol. 1999; 277: G12–21, [PUBMED], [INFOTRIEVE], [CSA]
- Logashenko E. B., Vladimirova A. V., Repkova M. N., Venyaminova A. G., Chernolovskaya E. L., Vlassov V. V. Silencing of MDR 1 gene in cancer cells by siRNA. Nucleosides Nucleotides Nucleic Acids 2004; 23: 861–866, [PUBMED], [INFOTRIEVE], [CROSSREF], [CSA]
- Manel N., Kim F. J., Kinet S., Taylor N., Sitbon M., Battini J. L. The ubiquitous glucose transporter GLUT-1 is a receptor for HTLV. Cell 2003; 115: 449–459, [PUBMED], [INFOTRIEVE], [CROSSREF], [CSA]
- McCaffrey A. P., Meuse L., Pham T. T., Conklin D. S., Hannon G. J., Kay M. A. RNA interference in adult mice. Nature 2002; 418: 38–39, [PUBMED], [INFOTRIEVE], [CROSSREF], [CSA]
- McManus M. T., Sharp P. A. Gene silencing in mammals by small interfering RNAs. Nat. Rev. Genet. 2002; 3: 737–747, [PUBMED], [INFOTRIEVE], [CROSSREF], [CSA]
- Miakotina O. L., Agassandian M., Shi L., Look D. C., Mallampalli R. K. Adenovirus stimulates choline efflux by increasing expression of organic cation transporter-2. Am. J. Physiol. Lung Cell Mol. Physiol. 2005; 288: L93–L102, [PUBMED], [INFOTRIEVE], [CROSSREF], [CSA]
- Miyagishi M., Taira K. U6 promoter-driven siRNAs with four uridine 3′ overhangs efficiently suppress targeted gene expression in mammalian cells. Nat. Biotechnol. 2002; 20: 497–500, [PUBMED], [INFOTRIEVE], [CROSSREF], [CSA]
- Mizuno N., Niwa T., Yotsumoto Y., Sugiyama Y. Impact of drug transporter studies on drug discovery and development. Pharmacol. Rev. 2003; 55: 425–461, [PUBMED], [INFOTRIEVE], [CSA]
- Myers J. W., Jones J. T., Meyer T., Ferrell J. E., Jr. Recombinant Dicer efficiently converts large dsRNAs into siRNAs suitable for gene silencing. Nat. Biotechnol. 2003; 21: 324–328, [PUBMED], [INFOTRIEVE], [CSA]
- Nieth C., Priebsch A., Stege A., Lage H. Modulation of the classical multidrug resistance (MDR) phenotype by RNA interference (RNAi). FEBS Lett. 2003; 545: 144–150, [PUBMED], [INFOTRIEVE], [CROSSREF], [CSA]
- Nishihara S., Ueda R., Goto S., Toyoda H., Ishida H., Nakamura M. Approach for functional analysis of glycan using RNA interference. Glycoconj. J. 2004; 21: 63–68, [PUBMED], [INFOTRIEVE], [CROSSREF], [CSA]
- Nykanen A., Haley B., Zamore P. D. ATP requirements and small interfering RNA structure in the RNA interference pathway. Cell 2001; 107: 309–321, [PUBMED], [INFOTRIEVE], [CROSSREF], [CSA]
- Paddison P. J., Caudy A. A., Bernstein E., Hannon G. J., Conklin D. S. Short hairpin RNAs (shRNAs) induce sequence-specific silencing in mammalian cells. Genes Dev. 2002; 16: 948–958, [PUBMED], [INFOTRIEVE], [CROSSREF], [CSA]
- Palauqui J. C., Elmayan T., Pollien J. M., Vaucheret H. Systemic acquired silencing: transgene-specific post-transcriptional silencing is transmitted by grafting from silenced stocks to non-silenced scions. Embo. J. 1997; 16: 4738–4745, [PUBMED], [INFOTRIEVE], [CROSSREF], [CSA]
- Pardridge W. M. Intravenous, non-viral RNAi gene therapy of brain cancer. Expert Opin. Biol. Ther. 2004; 4: 1103–1113, [PUBMED], [INFOTRIEVE], [CROSSREF], [CSA]
- Park M., Li Q., Shcheynikov N., Zeng W., Muallem S. NaBC1 is a ubiquitous electrogenic Na+#-coupled borate transporter essential for cellular boron homeostasis and cell growth and proliferation. Mol. Cell. 2004; 16: 331–341, [PUBMED], [INFOTRIEVE], [CROSSREF], [CSA]
- Peng Z., Xiao Z., Wang Y., Liu P., Cai Y., Lu S., Feng W., Han Z. C. Reversal of P‐glycoprotein-mediated multidrug resistance with small interference RNA (siRNA) in leukemia cells. Cancer Gene Ther. 2004, [CSA]
- Quinones H., Collazo R., Moe O. W. The dopamine precursor L-dihydroxyphenylalanine is transported by the amino acid transporters rBAT and LAT2 in renal cortex. Am. J. Physiol. Renal Physiol. 2004; 287: F74–80, [PUBMED], [INFOTRIEVE], [CROSSREF], [CSA]
- Reid G., Wielinga P., Zelcer N., van der Heijden I., Kuil A., de Haas M., Wijnholds J., Borst P. The human multidrug resistance protein MRP4 functions as a prostaglandin efflux transporter and is inhibited by nonsteroidal antiinflammatory drugs. Proc. Natl. Acad. Sci. USA. 2003; 100: 9244–9249, [PUBMED], [INFOTRIEVE], [CROSSREF], [CSA]
- Reynolds A., Leake D., Boese Q., Scaringe S., Marshall W. S., Khvorova A. Rational siRNA design for RNA interference. Nat. Biotechnol. 2004; 22: 326–330, [PUBMED], [INFOTRIEVE], [CROSSREF], [CSA]
- Rival T., Soustelle L., Strambi C., Besson M. T., Iche M., Birman S. Decreasing glutamate buffering capacity triggers oxidative stress and neuropil degeneration in the Drosophila brain. Curr. Biol. 2004; 14: 599–605, [PUBMED], [INFOTRIEVE], [CROSSREF], [CSA]
- Ross D. D. Modulation of drug resistance transporters as a strategy for treating myelodysplastic syndrome. Best Pract. Res. Clin. Haematol. 2004; 17: 641–651, [PUBMED], [INFOTRIEVE], [CROSSREF], [CSA]
- Rubinson D. A., Dillon C. P., Kwiatkowski A. V., Sievers C., Yang L., Kopinja J., Rooney D. L., Ihrig M. M., McManus M. T., Gertler F. B., Scott M. L., Van Parijs L. A lentivirus-based system to functionally silence genes in primary mammalian cells, stem cells and transgenic mice by RNA interference. Nat. Genet. 2003; 33: 401–406, [PUBMED], [INFOTRIEVE], [CROSSREF], [CSA]
- Russel F. G., Masereeuw R., van Aubel R. A. Molecular aspects of renal anionic drug transport. Annu. Rev. Physiol. 2002; 64: 563–594, [PUBMED], [INFOTRIEVE], [CROSSREF], [CSA]
- Said H. M., Balamurugan K., Subramanian V. S., Marchant J. S. Expression and functional contribution of hTHTR-2 in thiamin absorption in human intestine. Am. J. Physiol. Gastrointest. Liver Physiol. 2004; 286: G491–498, [PUBMED], [INFOTRIEVE], [CROSSREF], [CSA]
- Schiffelers R. M., Ansari A., Xu J., Zhou Q., Tang Q., Storm G., Molema G., Lu P. Y., Scaria P. V., Woodle M. C. Cancer siRNA therapy by tumor selective delivery with ligand-targeted sterically stabilized nanoparticle. Nucleic Acids Res. 2004a; 32: e149, [PUBMED], [INFOTRIEVE], [CROSSREF], [CSA]
- Schiffelers R. M., Woodle M. C., Scaria P. Pharmaceutical prospects for RNA interference. Pharm. Res. 2004b; 21: 1–7, [PUBMED], [INFOTRIEVE], [CROSSREF], [CSA]
- Shepard R. L., Cao J., Starling J. J., Dantzig A. H. Modulation of P-glycoprotein but not MRP1- or BCRP-mediated drug resistance by LY335979. Int. J. Cancer. 2003; 103: 121–125, [PUBMED], [INFOTRIEVE], [CROSSREF], [CSA]
- Sijen T., Fleenor J., Simmer F., Thijssen K. L., Parrish S., Timmons L., Plasterk R. H., Fire A. On the role of RNA amplification in dsRNA-triggered gene silencing. Cell 2001; 107: 465–476, [PUBMED], [INFOTRIEVE], [CROSSREF], [CSA]
- Soares-Da-Silva P., Serrao M. P., Pinho M. J., Bonifacio M. J. Cloning and gene silencing of LAT2, the L-3,4-dihydroxyphenylalanine (L-DOPA) transporter, in pig renal LLC-PK1 epithelial cells. Faseb. J. 2004; 18: 1489–1498, [PUBMED], [INFOTRIEVE], [CROSSREF], [CSA]
- Song E., Lee S. K., Wang J., Ince N., Ouyang N., Min J., Chen J., Shankar P., Lieberman J. RNA interference targeting Fas protects mice from fulminant hepatitis. Nat. Med. 2003; 9: 347–351, [PUBMED], [INFOTRIEVE], [CROSSREF], [CSA]
- Song Y. K., Liu F., Zhang G., Liu D. Hydrodynamics-based transfection: simple and efficient method for introducing and expressing transgenes in animals by intravenous injection of DNA. Methods Enzymol. 2002; 346: 92–105, [PUBMED], [INFOTRIEVE], [CSA]
- Stege A., Priebsch A., Nieth C., Lage H. Stable and complete overcoming of MDR1/P‐glycoprotein-mediated multidrug resistance in human gastric carcinoma cells by RNA interference. Cancer Gene Ther. 2004, [CSA]
- Stierle V., Laigle A., Jolles B. The reduction of P-glycoprotein expression by small interfering RNAs is improved in exponentially growing cells. Oligonucleotides 2004; 14: 191–198, [PUBMED], [INFOTRIEVE], [CROSSREF], [CSA]
- Suzuki H., Sugiyama Y. Single nucleotide polymorphisms in multidrug resistance associated protein 2 (MRP2/ABCC2): its impact on drug disposition. Adv. Drug Deliv. Rev. 2002; 54: 1311–1331, [PUBMED], [INFOTRIEVE], [CROSSREF], [CSA]
- Takino T., Takahashi T. T. O. Clinical study of the consitutional hyperbilirubinemia in Japan: a nationwide survey between 1970 and 1974. Nippon Shokakibyo Gakkai Zasshi 1977; 74: 1518–1528, [PUBMED], [INFOTRIEVE], [CSA]
- Thakker D. R., Natt F., Husken D., Maier R., Muller M., van der Putten H., Hoyer D., Cryan J. F. Neurochemical and behavioral consequences of widespread gene knockdown in the adult mouse brain by using nonviral RNA interference. Proc. Natl. Acad. Sci. USA. 2004; 101: 17270–17275, [PUBMED], [INFOTRIEVE], [CROSSREF], [CSA]
- Tian X., Zamek-Gliszczynski M. J., Zhang P., Brouwer K. L. Modulation of multidrug resistance-associated protein 2 (Mrp2) and Mrp3 expression and function with small interfering RNA in sandwich-cultured rat hepatocytes. Mol. Pharmacol. 2004; 66: 1004–1010, [PUBMED], [INFOTRIEVE], [CROSSREF], [CSA]
- Tiscornia G., Singer O., Ikawa M., Verma I. M. A general method for gene knockdown in mice by using lentiviral vectors expressing small interfering RNA. Proc. Natl. Acad. Sci. USA. 2003; 100: 1844–1848, [PUBMED], [INFOTRIEVE], [CROSSREF], [CSA]
- Tomar R. S., Matta H., Chaudhary P. M. Use of adeno-associated viral vector for delivery of small interfering RNA. Oncogene 2003; 22: 5712–5715, [PUBMED], [INFOTRIEVE], [CROSSREF], [CSA]
- Turncliff R. Z., Meier P. J., Brouwer K. L. Effect of dexamethasone treatment on the expression and function of transport proteins in sandwich-cultured rat hepatocytes. Drug Metab. Dispos. 2004; 32: 834–839, [PUBMED], [INFOTRIEVE], [CROSSREF], [CSA]
- Van Aubel R. A., Smeets P. H., Van Den Heuvel J. J., Russel F. G. Human organic anion transporter MRP4 (ABCC4) is an efflux pump for the purine end metabolite urate with multiple allosteric substrate binding sites. Am. J. Physiol. Renal. Physiol. 2004, [CSA]
- Vavricka S. R., Musch M. W., Chang J. E., Nakagawa Y., Phanvijhitsiri K., Waypa T. S., Merlin D., Schneewind O., Chang E. B. hPepT1 transports muramyl dipeptide, activating NF-kappaB and stimulating IL-8 secretion in human colonic Caco2/bbe cells. Gastroenterology 2004; 127: 1401–1409, [PUBMED], [INFOTRIEVE], [CROSSREF], [CSA]
- Wang N., Lan D., Chen W., Matsuura F., Tall A. R. ATP-binding cassette transporters G1 and G4 mediate cellular cholesterol efflux to high-density lipoproteins. Proc. Natl. Acad. Sci. USA. 2004; 101: 9774–9779, [PUBMED], [INFOTRIEVE], [CROSSREF], [CSA]
- Weber W., Malphettes L., de Jesus M., Schoenmakers R., El-Baba M. D., Spielmann M., Keller B., Weber C. C., van de Wetering P., Aubel D., Wurm F. M., Fussenegger M. Engineered streptomyces quorum-sensing components enable inducible siRNA-mediated translation control in mammalian cells and adjustable transcription control in mice. J. Gene Med. 2004, [CSA]
- Witola W. H., Inoue N., Ohashi K., Onuma M. RNA-interference silencing of the adenosine transporter-1 gene in Trypanosoma evansi confers resistance to diminazene aceturate. Exp. Parasitol. 2004; 107: 47–57, [PUBMED], [INFOTRIEVE], [CROSSREF], [CSA]
- Wu C. Y., Benet L. Z. Disposition of tacrolimus in isolated perfused rat liver: influence of troleandomycin, cyclosporine, and gg918. Drug Metab. Dispos. 2003; 31: 1292–1295, [PUBMED], [INFOTRIEVE], [CROSSREF], [CSA]
- Wu H., Hait W. N., Yang J. M. Small interfering RNA-induced suppression of MDR1 (P‐glycoprotein) restores sensitivity to multidrug-resistant cancer cells. Cancer Res. 2003; 63: 1515–1519, [PUBMED], [INFOTRIEVE], [CSA]
- Xu D., Kang H., Fisher M., Juliano R. L. Strategies for inhibition of MDR1 gene expression. Mol. Pharmacol. 2004; 66: 268–275, [PUBMED], [INFOTRIEVE], [CROSSREF], [CSA]
- Yague E., Higgins C. F., Raguz S. Complete reversal of multidrug resistance by stable expression of small interfering RNAs targeting MDR1. Gene Ther. 2004; 11: 1170–1174, [PUBMED], [INFOTRIEVE], [CROSSREF], [CSA]
- Yang D., Goga A., Bishop J. M. RNA interference (RNAi) with RNase III-prepared siRNAs. Methods Mol. Biol. 2004; 252: 471–482, [PUBMED], [INFOTRIEVE], [CSA]
- Yu J. Y., DeRuiter S. L., Turner D. L. RNA interference by expression of short-interfering RNAs and hairpin RNAs in mammalian cells. Proc. Natl. Acad. Sci. USA. 2002; 99: 6047–6052, [PUBMED], [INFOTRIEVE], [CROSSREF], [CSA]
- Zhang G., Gao X., Song Y. K., Vollmer R., Stolz D. B., Gasiorowski J. Z., Dean D. A., Liu D. Hydroporation as the mechanism of hydrodynamic delivery. Gene Ther 2004; 11: 675–682, [PUBMED], [INFOTRIEVE], [CROSSREF], [CSA]
- Zhang Y., Boado R. J., Pardridge W. M. In vivo knockdown of gene expression in brain cancer with intravenous RNAi in adult rats. J. Gene Med. 2003; 5: 1039–1045, [PUBMED], [INFOTRIEVE], [CROSSREF], [CSA]
- Zheng L., Liu J., Batalov S., Zhou D., Orth A., Ding S., Schultz P. G. An approach to genomewide screens of expressed small interfering RNAs in mammalian cells. Proc. Natl. Acad. Sci. USA. 2004; 101: 135–140, [PUBMED], [INFOTRIEVE], [CROSSREF], [CSA]