References
- Buee , L. , Hof , P. R. , Bouras , C. , Delacourte , A. , Peri , D. P. , Morrison , J. H. and Fillit , H. M. 1994 . Pathological alterations of the cerebral microvasculature in Alzheimer's disease and related dementing disorders . Acta Neuropathologica , 87 : 469 – 480 .
- Burns , E. M. , Kruckeberg , T. W. and Gaetano , P. K. 1981 . Changes with age in cerebral capillary morphology . Neurobiology of Aging , 2 : 285 – 291 .
- Cervos-Navarro , J. , Gertz , H. J. and Frydl , V. 1987 . Cerebral blood vessel changes in old people . Mechanisms of Ageing and Development , 39 : 223 – 231 .
- D'Amelio , F. E. , Smith , M. E. and Eng , L. F. 1990 . Sequence of tissue responses in the early stages of experimental allergic encephalomyelitis (EAE): Immunohistochemical, light microscopic, and ultrastructural observations in the spinal cord . Glia , 3 : 229 – 240 .
- Davies , D. C. and Hardy , J. A. 1988 . Blood brain barrier in ageing and Alzheimer's disease . Neurobiolooy of Aging , 9 : 46 – 47 .
- Eng , L. F. , D'Amelio , F. E. and Smith , M. E. 1989 . Dissociation of GFAP intermediate filaments in EAE: Observations in the lumbar spinal cord . Gila , 2 : 308 – 317 .
- Fischer , V. W. , Siddiqi , A. and Yusufaly , Y. 1990 . Altered angioarchitecture in selected areas of brains with Alzheimer's disease . Acta Neuropathologica , 79 : 672 – 679 .
- Fraser , S. P. , Suh , Y. H. and Djamgoz , M. B. A. 1997 . Ionic effects of the Alzheimer's disease Beta-amyloid precursor protein and its metabolic fragments . Trends in Neuroscience , 20 : 67 – 72 .
- Jeong , S. J. , Kim , K. and Suh , Y. H. 1997 . Age-related changes in the expression of Alzheimer's beta APP in the brain of senescence accelerated mouse (SAM)-P/10 . Neuroreport , 8 : 1733 – 1737 .
- Kalaria , R. N. 1992 . The blood-brain barrier and cerebral microcirculation in Alzheimer's disease . Cerebrovascular and Brain Metabolism Reviews , 4 : 226 – 260 .
- Kimelberg , H. K. 1995 . “ Brain edema ” . In Neuroolia , Edited by: Kettenmann , H. and Ransom , B. R. 919 – 935 . New York : Oxford University Press .
- Lee , E. Y. , Lee , T. S. , Baik , S. H. and Cha , C. I. 1998 . Postnatal development of somatostatin- and neuropeptide Y-immunoreactive neurons in rat cerebral cortex: A double-labeling immunohistochemical study . International Journal of Developmental Neuroscience , 16 : 63 – 72 .
- Luckman , S. M. and Bicknell , R. J. 1990 . Morphological plasticity that occurs in the neurohypophysis following activation of the magnocellular neurosecretory system can be mimicked in vitro by Beta-adrenergic stimulation . Neuroscience , 39 : 701 – 709 .
- Mato , M. , Ookawara , S. and Kurihara , K. 1980 . Uptake of exogenous substance and marked infoldings of fluorescent granular pericytes in cerebral fine vessels . American Journal of Anatomy , 157 : 329 – 332 .
- Perlmutter , L. S. and Chui , H. C. 1990 . Microangiopathy, the vascular basement membrane and Alzheimer's disease: A review . Brain Research Bulletin , 24 : 677 – 686 .
- Peters , A. , Josephson , K. and Vincent , S. L. 1991 . Effects of aging on the neuroglial cells and pericytes within area 17 of the rhesus monkey cerebral cortex . The Anatomical Record , 229 : 384 – 398 .
- Petito , C. K. , Schaefer , J. A. and Plum , F. 1977 . Ultrastructural characteristics of the brain and blood-brain barrier in experimental seizures . Brain Research , 127 : 251 – 267 .
- Takeda , T. , Hosokawa , M. and Higuchi , K. 1997 . Senescence-accelerated mouse (SAM): a novel murine model of senescence . [Review.] Experimental Gerontology , 32 : 105 – 109 .
- Takeda , T. , Hosokawa , M. , Takeshita , S. , Irino , M. , Higuchi , K. , Matsushita , T. , Tomita , Y. , Yasuhira , K. , Hamamoto , H. , Shimizu , K. , Ishii , M. and Yamamuro , T. 1981 . A new murine model of accelerated senescence . Mechanisms of Ageing and Development , 17 : 911 – 919 .
- Theodosis , D. T. and MacVicar , B. 1996 . Neurone-glia interactions in the hypothalamus and pituitary . Trends in Neuroscience , 19 : 363 – 367 .
- Torre , J. C. and Mussivand , T. 1993 . Can disturbed brain microcirculation cause Alzheimer's disease? . Neuroscience Research , 15 : 146 – 153 .
- Ueno , M. , Akiguchi , I. , Hosokawa , M. , Shinnou , M. , Sakamoto , H. , Takemura , M. and Higuchi , K. 1997a . Age-related changes in the brain transfer of blood-borne horseradish peroxidase in the hippocampus of senescence-accelerated mouse . Acta Neuropathologica , 93 : 233 – 240 .
- Ueno , M. , Dobrogowska , D. H. and Vorbrodt , A. W. 1996 . Immunocytochemical evaluation of the blood-brain barrier to endogenous albumin in the olfactory bulb and pons of senescence-accelerated mice (SAM) . Histochemistry and Cell Biology , 105 : 203 – 212 .
- Vinters , H. V. , Secor , D. L. , Read , S. L. , Frazee , J. G. , Tomiyasu , U. , Stanley , T. M. , Ferreiro , J. A. and Akers , M. A. 1994 . Microvasculature in brain biopsy specimens from patients with Alzheimer's disease: An immunohistochemical and ultrastructural study . Ultrastructural Pathology , 18 : 333 – 348 .
- Westergaard , E. , van Deurs , B. and Brondsted , H. E. 1977 . Increased vesicular transfer of horseradish peroxidase across cerebral endothelium, evoked by acute hypertension . Acta Neuropathologica , 37 : 141 – 152 .
- Yamagata , K. , Tagami , M. , Nara , Y. , Fugino , H. , Kubota , A. , Numano , F. , Kato , T. and Yamori , Y. 1997 . Faulty induction of blood-brain barrier functions by astrocytes isolated from stroke-prone spontaneously hypertensive rats . Clinical and Experimental Pharmacology Physiology , 24 : 686 – 691 .
- Raichle , M. E. , Hartman , B. K. , Eichling , J. O. and Sharpe , L. G. 1975 . Central noradrenergic regulation of cerebral flow and vascular permeability . Proceedings of National Academy and Science of USA , 72 : 3726 – 3730 .
- Rapoport , S. I. 1994 . Aging and the blood-brain barrier . Neurobiology of Aging , 15 : 759760
- Risau , W. and Wolburg , H. 1990 . Development of the blood-brain barrier . Trends in Neuroscience , 13 : 174 – 178 .
- Rosner , H. and Vacun , G. 1997 . Organotypic spinal cord culture in serum-free fibrin gel: A new approach to study three-dimensional neurite outgrowth and of neurotoxicity testing . Effects of modulating the actin and tubulin dynamics and protein kinase activities. Journal of Neuroscience Methods , 78 : 93 – 103 .
- Scheibel , A. B. , Duong , T. and Jacob , R. 1989 . Alzheimer's disease as a capillary dementia . Annals of Medicine , 21 : 103 – 107 .
- Shimada , A. , Hosokawa , M. , Ohta , A. , Akiguchi , I. and Takeda , T. 1994 . Localization of atrophy-prone areas in the aging mouse brain: Comparison between the brain atrophy model SAM-P/10 and the normal control SAM-R/1 . Neuroscience , 59 : 859 – 869 .
- Stewart , P. A. , Hayakawa , K. , Akers , M. A. and Vinters , H. V. 1992 . A morphometric study of the blood-brain barrier in Alzheimer's disease . Laboratory Investigation , 6 : 734 – 742 .
- Ueno , M. , Akiguchi , I. , Hosokawa , M. , Shinnou , M. , Sakamoto , H. , Takemura , M. and Higuchi , K. 1997b . Age-related changes in barrier function in mouse brain . II. Accumulation of serum albumin in the olfactory bulb of SAM mice increased with aging. Archives of Gerontology and Geriatrics , 25 : 321 – 331 .
- Mato , M. , Ookawara , S. , Sakamoto , A. , Aikawa , E. , Ogawa , T. , Mitsuhashi , U. , Masuzawa , T. , Suzuki , H. , Honda , M. , Yazaki , Y. , Watanabe , E. , Luoma , J. , Yla-Herttuala , S. , Fraser , I. , Gordon , S. and Kodama , T. 1996 . Involvement of specific macrophage-lineage lineage cells surrounding arterioles in barrier and scavenger function in brain cortex . Proceedings of National Academy Science of USA , 93 : 3269 – 3274 .
- Mattson , M. P. , Barger , S. W. , Furukawa , K. , Bruce , A. J. , Wyss-Coray , T. , Mark , R. J. and Mucke , L. 1997 . Cellular signaling roles of TGF beta, TNF alpha and beta APP in brain injury responses and Alzheimer's disease . Brain Research Brain Research Review , 23 : 47 – 61 .
- Mooradian , A. D. 1988 . Effect of aging on the blood-brain barrier . Neurobiology of Aging , 9 : 31 – 39 .
- Mooradian , A. D. 1994 . Potential mechanisms of the age-related changes in the blood-brain barrier . Neurobiology of Aging , 15 : 751 – 755 .
- Ookawara , S. , Mitsuhashi , U. , Suminaga , Y. and Mato , M. 1996 . Study on distribution and fluorescent granular perithelial (FGP) cell in the transitional region between arteriole and capillary in rat cerebral cortex . The Anatomical Record , 244 : 257 – 264 .