The measurement of biological age

References

• Alexander , P. 1966 . “ Is there a relationship between aging, the shortening of life span by radiation and the induction of somatic-mutations? ” . In Perspectives in experimental gerontology. , Edited by: Shock , N. W. Springfield : Charles C. Thomas .
   Google Scholar
• Ball , J. P. and Squire , J. R. 1949 . A study of mortality in a burn unit. . Annals of surgery , 130 : 160 – 167 .
   PubMed Web of Science ®Google Scholar
• Beisswenger , P. J. and Sprio , G. R. 1970 . Human glomerular basement membrane: chemical alternation in diabetes mellitus. . Science , 168 : 596
   PubMed Web of Science ®Google Scholar
• Berkman , J. and Rifkin , H. 1966 . Newer aspects of diabetic microangiopathy. . Annual Review of Medicine , 17 : 83 – 112 .
   PubMed Web of Science ®Google Scholar
• Bourne , G. H. 1961 . Structural aspects of aging. , 419 New York : Hafner Publishing Company .
   Google Scholar
• Boyd , E. 1932 . The weight of the thymus gland in health and disease. . American Journal of Diseases of Children , 43 : 1162 – 1214 .
   Google Scholar
• Brocklehurst , J. C. 1978 . Textbook of geriatric medicine and gerontology. , 341 Edinburgh-London-New York : Churchill-Livingstone .
   Google Scholar
• Brody , H. 1955 . Organization of cerebral cortex. III. A study of aging in the human cerebral cortex. . Journal of Comparative Neurology , 102 : 511 – 556 .
   PubMed Web of Science ®Google Scholar
• Brody , H. 1060 . The depostion of aging pigment in the human cerebral cortex. . Journal of Gerontology , 15–16 : 258 – 261 .
   Google Scholar
• Brody , H. 1970 . “ Structural changes in the aging nervous system ” . In The regulatory role of the nervous system in aging: Interdisciplimary topics in gerontology, 7 , Edited by: Blumenthal , H. T. 9 – 21 . München : Karger, Basel .
   Google Scholar
• Brody , H. 1976 . “ An examination of cerebral cortex and brainstem aging ” . In Neurobiology of aging , Edited by: Terry , R. D. and Gershon , S. Vol. 3 , 177 – 181 . New York : Raven Press . Aging Series
   Google Scholar
• Brooks , A. L. , Mead , D. K. and Peters , R. F. 1973 . Effect of aging on the frequency of metaphase chromosome abberations in the liver of the Chinese Hamster. . Journal of Gerontology , 28 : 452 – 454 .
   PubMedGoogle Scholar
• Brues , A. M. and Sacher , G. A. , eds. 1965 . Aging and levels of biological organization. , Chicago : University of Chicago Press .
   Google Scholar
• Burnet , Sir Frank McFarlane . 1969 . Cellular immunology. , 725 Melbourne : Melbourne University Press .
   Google Scholar
• Chvapil , M. and Hruza . 1959 . The influence of aging and undernutriton on chemical contractility and relaxation of collagen fibers in rats. . Gerontologia , 3 : 241
   PubMedGoogle Scholar
• Comfort , A. 1972 . Measuring the human ageing rate. . Mechanisms of Aging and Development , 1 : 101 – 110 .
   Web of Science ®Google Scholar
• Comfort , A. 1963 . Mutation, autoimmunity, and aging. . The Lancet , 11 : 138 – 140 .
   Google Scholar
• Comfort , A. 1956 . The Biology of Senescence. , London : Routledge and Kegan Paul .
   Google Scholar
• Crossfill , M. L. , Lindop , P. J. and Rotblat , J. 1959 . Variation of sensitivity to ionizing radiation with age. . Nature , 183 : 1729 – 1730 .
   PubMed Web of Science ®Google Scholar
• Crowley , C. and Curtis , H. 1963 . The development of somatic mutations in mice with age. . Proceedings of the National Academy of Sciences of the United States of America , 49 : 626 – 628 .
   PubMed Web of Science ®Google Scholar
• Curtis , H. and Crowley , C. 1953 . Chromosome aberrations in liver cells in relation to the somatic mutation theory of aging. . Radiation Research , 18–19 : 337 – 344 .
   Google Scholar
• Curtis , H. and Miller , K. 1971 . Chromosome aberrations in liver cells of guinea pigs. . Journal of Gerontology , 26 : 292 – 293 .
   PubMedGoogle Scholar
• Darmady , E. M. , Offer , J. and Woodhouse , M. A. 1973 . The parameters of the ageing kidney. . Journal of Pathology , 109 : 195 – 206 .
   PubMed Web of Science ®Google Scholar
• Davies , O. L. , ed. 1956 . “ 2 ” . In The design and analysis of industrial experiments. , New York : Oliver and Boyd, London and Edinburgh, Hafner Publishing Company . Chapter
   Google Scholar
• Dodt , E. 1955 . Zur Frage der thermoelastischen Eigenschaften des Nerven. . Experientia , 11 : 65
   PubMedGoogle Scholar
• Ellis , R. S. 1921 . Norms for some structural changes in the human cerebellum from birth to old age. . Journal of Comparative Neurology , 32 : 1 – 33 .
   Google Scholar
• Franke , H. 1978 . Aktuelle Probleme der Gerontologie und Geriatrie . Naturwissenschaften , 61 : 150 – 156 .
   Web of Science ®Google Scholar
• Gaffney , G. W. , Gregernan , R. I. , Yiengst , M. J. and Shock , N. W. 1960 . Serum protein-bound iodine concentration in blood of euthyroid man aged 18–94 years. . Journal of Gerontology , 15 : 234 – 241 .
   PubMedGoogle Scholar
• Goldstein , S. 1969 . Life span of cultured cells in progeria. . Lancet , 11 : 424
   Google Scholar
• Goldstein , S. , Littlefield , J. W. and Soeldner , J. S. 1969 . Diabetes mellitus and aging. Diminished plating efficiency of cultured human fibroblasts. . Proceedings of the National Academy of Sciences of the United States of America. , 64 : 155 – 160 .
   PubMed Web of Science ®Google Scholar
• Gompertz , B. 1825 . On the nature of the law of human mortality and a new mode of determining life contingencies. . Philosophical Transactions of the Royal Society of London. Series B , 115 : 513 – 585 .
   Google Scholar
• Gregerman , R. I. , Gaffney , G. W. , Shock , N. W. and Crowder , S. E. 1962 . Thyroxine turnover in euthyroid man with special reference to changes with age. . Journal of Clinical Investigation , 41 : 2065
   PubMed Web of Science ®Google Scholar
• Hayflick , L. 1968 . Human cells and aging. . Scientific American , 218 : 32 – 37 .
   PubMed Web of Science ®Google Scholar
• Hayflick , L. 1980 . The cell biology of human aging. . Scientific American , 242 : 58 – 65 .
   PubMed Web of Science ®Google Scholar
• Hayflick , L. 1966 . “ Cell culture and the aging phenomenon. In ” . In Topics in the biology of aging. , 83 – 100 . New York : Interscience Publishers .
   Google Scholar
• Hayflick , L. 1965 . The limited in vitro lifetime of human diploid cell strains . Experimental Cell Research , 37 : 614 – 636 .
   PubMed Web of Science ®Google Scholar
• Hayflick , L. 1975 . The cellular basis of biological age. . Verhandlungen der Deutschen Gesellschaft für Pathologie , 59 : 52 – 66 .
   PubMedGoogle Scholar
• Hempel , K. 1968 . Quantitative und Topische Probleme der Altersvorgänge im Gehirn. . Verhandlungen der Deutschen Gesellschaft für Pathologie , 52 : 179 – 203 .
   PubMedGoogle Scholar
• Hensley , J. C. , McWilliams , P. C. and Oakley , G. E. 1964 . Physiological capacitance: A study in physiological age determination. . Journal of Gerontology , 19 : 317 – 321 .
   PubMedGoogle Scholar
• Hirokawa , K. and Makinodan , T. 1975 . Thymic involution: Effect of T-cell differentiation. . Journal of Immunology , 114 : 1659 – 1669 .
   PubMed Web of Science ®Google Scholar
• Hodgke , C. F. 1894 . Changes in ganglion cells from birth to senile death; Observations of man and honeybee. . Journal of Physiology. , 17 : 129 – 134 .
   Google Scholar
• Howell , T. H. 1949 . Old age. . Geriatrics , 4 : 281 – 291 .
   PubMedGoogle Scholar
• Howell , T. H. 1963 . Multiple pathology in nonagenarians. . Geriatrics , 18 : 899 – 902 .
   PubMed Web of Science ®Google Scholar
• Howell , T. H. 1968 . Multiple pathology in a septuagenarian. . Journal of the American Geriatrics Society , 16 : 760 – 762 .
   PubMed Web of Science ®Google Scholar
• Howell , T. H. and Piggot , A. P. 1951 . Morbid anatomy of old age I and II. . Geriatrics , 6 : 85 – 95 .
   PubMedGoogle Scholar
• Howell , T. H. and Piggot , A. P. 1952 . Morbid anatomy of old age III. . Geriatrics , 7 : 137 – 142 .
   PubMedGoogle Scholar
• Johnson , H. A. and Erner , S. 1972 . Neuronal survival and the aging mouse. . Experimental Gerontology , 7 : 111 – 117 .
   PubMed Web of Science ®Google Scholar
• Kohn , H. I. and Kallman , R. F. 1956 . Age, growth, and the LD-50 of x-rays. . Science , 124 : 1078
   PubMed Web of Science ®Google Scholar
• Kohn , R. R. 1963 . Human aging and disease. . Journal of Chronic Diseases , 16 : 5 – 21 .
   PubMedGoogle Scholar
• Konigsmark , B. 1969 . “ Methods for the counting of neurons ” . In Contemporary research method in neuroanatomy. , Edited by: Nauta , J. M. and Ebesson , S. O. 365 New York : Springer .
   Google Scholar
• Landfield , P. , Rose , G. , Sandles , L. , Wohlstadler , T. C. and Lynch , G. 1977 . Patterns of astroglial hypertrophy and neuronal degeneration in the hippocampus of aged, memory-deficient rats. . Journal of Gerontology , 82 : 3 – 12 .
   Google Scholar
• Landfield , P. , Waymire , J. C. and Lynch , G. 1978 . Hippocampal aging and adrenocortiocoids: Quantitative correlations. . Science , 202 : 1098 – 1102 .
   PubMed Web of Science ®Google Scholar
• Lindop , P. and Rotblat , J. 1962 . “ Induction of aging by radiation ” . In Biological aspects of aging: The effect of environmental factors of aging. , Edited by: Shock , N. W. 216 – 221 . New York : Columbia University Press .
   Google Scholar
• Linzbach , A. J. and Akuamoa-Boateng , E. 1973 . Die Altersveränderungen des menschlichen Herzens. I. Das Herzgewicht im Alter. . Klinische Wochenschrift , 51 : 156 – 163 .
   PubMedGoogle Scholar
• Linzbach , A. J. and Akuamoa-Boateng , E. 1973 . Die Altersveränderungen des Menschlichen Herzens. II. Die Polypathie des Herzens im Alter. . Klinische Wochenschrift , 51 : 164 – 175 .
   PubMedGoogle Scholar
• Linzbach , A. J. 1975 . Altern und Krankheit. Ableitung einer neuen Alterstheorie auf der Grundlage der Polypathie. . Verhandlungen der Deutschen Gesellschaft für Pathologie , 59 : 242 – 251 .
   PubMedGoogle Scholar
• Ludwig , F. C. and Silverman , L. 1975 . Measuring of biological age in samples of kidney and brain obtained at autopsy from rats. . Verhandlungen der Deutschen Gesellschaft für Pathologie , 59 : 242 – 251 .
   PubMedGoogle Scholar
• Makinodan , T. 1972 . Tolerance, autoimmunity, and aging. , Springfield : Charles C. Thomas .
   Google Scholar
• Martin , D. N. 1979 . Morphologic lesions in aging Syrian hamsters. . Journal of Gerontology , 34 : 502 – 511 .
   PubMedGoogle Scholar
• Martin , G. M. , Sprague , C. A. and Epstein , C. J. 1970 . Replicative lifespan of cultivated human cells. . Laboratory Investigation , 23 : 86 – 92 .
   PubMed Web of Science ®Google Scholar
• Meredith , P. , Gerbase-Delima , M. and Walford , R. L. 1972 . Age-related changes in the PMA: Con A stimulatory ratios of cells from spleens of a long-lived mouse strain. . Experimental Gerontology , 10 : 247 – 250 .
   Web of Science ®Google Scholar
• Miquel , J. , Oro , J. , Bensch , K. G. and Johnson , J. E. Jr. 1977 . “ Lipofuscin: Fine-structural and biochemical studies. In ” . In Free radicals in biology. Vol. III. , 133 – 152 . New York-San Francisco-London : Academic Press .
   Google Scholar
• Mostofi , F. K. , Antonovych , T. T. and Limas , E. 1971 . Patterns of glomerular reaction to injury. . Human Pathology , 2 : 233 – 252 .
   PubMed Web of Science ®Google Scholar
• Owen , D. B. 1962 . Handbook of statistical tables. , 44 Reading, Mass : Addison-Wesley Publishing Company, Inc. .
   Google Scholar
• Reichel , W. , Hollander , J. , Clark , J. M. and Strehler , B. L. 1968 . Lipofuscin pigment accummulation as a function of age and distribution of rodent brain. . Journal of Gerontology , 23 : 71 – 78 .
   PubMedGoogle Scholar
• Rose , G. , Lynch , G. and Cotman , C. W. 1976 . Hypertrophy and redistribution of astrocytes in the deafferented dentate gyrus. . Brain Research Bulletin , 1 : 87 – 92 .
   PubMed Web of Science ®Google Scholar
• Ross , M. H. 1961 . Length of life and nutrition in the rat. . Journal of Nutrition , 75 : 197 – 210 .
   PubMed Web of Science ®Google Scholar
• Rose , M. H. 1959 . Protein, calories, and life expectancy. . Federation Proceedings , 18 : 1190 – 1207 .
   PubMedGoogle Scholar
• Sacher , G. A. 1957 . Dependence of acute ratiosensitivity of age in the adult female mouse. . Science , 125 : 1039 – 40 .
   PubMed Web of Science ®Google Scholar
• Samorajski , R. , Ordy , J. M. and Keefe , J. R. 1965 . The fine structure of lipofuscin age pigment in the nervous system of aged mice. . Jounral of Cell Biology. , 26 : 779 – 795 .
   PubMed Web of Science ®Google Scholar
• Samorajski , T. , Keefe , J. R. and Ordy , J. M. 1964 . Intracellular localization of lipofuscin age pigment in the nervous system. . Journal of Gerontology , 19 : 262 – 272 .
   PubMedGoogle Scholar
• Simms , H. S. and Berg , B. N. 1962 . Longevity in relation to lesion onset. . Geriatrics , 17 : 235 – 242 .
   PubMed Web of Science ®Google Scholar
• Siperstein , M. D. 1972 . Capillary basement membranes in diabetic microangiopathy. . Advances in Internal Medicine , 18 : 325
   PubMedGoogle Scholar
• Stobo , J. D. and Paul , W. E. 1973 . Functional heterogeneity of murine lymphoid cells. III. Differential responsiveness of T cells to phytohemagglutinin and concanavilin A as a probe for T cell subsets. . The Journal of Immunology , 110 : 362 – 375 .
   PubMed Web of Science ®Google Scholar
• Storer , J. B. 1962 . Evaluation of radiation response as an index of aging in mice. . Radiation Research , 17 : 878 – 902 .
   PubMed Web of Science ®Google Scholar
• Strehler , B. L. , Mark , D. D. , Mildvan , A. S. and Gee , M. V. 1959 . Rate and magnitude of age pigment accumulation in the human myocardium. . Journal of Gerontology , 14 : 430 – 439 .
   PubMedGoogle Scholar
• Strehler , B. 1976 . “ Introduction: Aging and the human brain ” . In Neurobiology of aging, Aging Series , Edited by: Terry , R. D. and Gershon , S. Vol. 3 , 1 – 22 . New York : Raven Press .
   Google Scholar
• Strehler , B. L. 1977 . Time, cells, and aging. , New York-San Francisco-London : Academic Press .
   Google Scholar
• Soukupova , M. and Holeckova , E. 1964 . The latent period of explanted organs of newborn, adult, and senile rats. . Experimental Cell Research , 33 : 361 – 367 .
   PubMed Web of Science ®Google Scholar
• Verzar , F. 1955 . Veränderungen der thermoelastischen Eigenschaften von Sehnenfasern beim Altern. . Experientia , 11 : 230
   PubMedGoogle Scholar
• Walford , R. 1969 . The immunologic theory of aging. , Copenhagen : Munksgaard .
   Google Scholar
• Wilson , L. A. , Lawson , I. R. and Brass , W. 1962 . Multiple disorders in the elderly. . Lancet , 11 : 841 – 843 .
   Google Scholar
• Wisniewski , H. M. , Ghetti , B. and Terry , R. D. 1973 . Neuritic (senile) plaques and filamentous changes in aged Rhesus Monkeys. . Journal of Neuropathology and Experimental Neurology , 32 : 566 – 584 .
   PubMed Web of Science ®Google Scholar
• Wisniewski , H. M. and Terry , R. D. 1976 . “ Neuropathology of the aging brain ” . In Neurobiology of aging, Aging Series , Edited by: Terry , R. D. and Gershon , S. Vol. 3 , 265 – 280 . New York : Raven Press .
   Google Scholar
• Wöhlisch , E. 1931 . Ein optisches Lineardilatometer zur Erforschung der thermoelastischen Eigenschaften des Muskels. . Zeitschrift für Biologie , 91 : 137 – 151 .
   Google Scholar