Lower femoral neck bone mineral density (BMD) in elderly women not on statins

References

• Chen, P., J. Sun, Y. Tsuang, M. Chen, P. Weng, and F. Lin. 2010. Simvastatin promotes osteoblast viability and differentiation via Ras/Smad/Erk/BMP-2 signaling pathway. Nutrition Research 30 (3):191–99. doi:10.1016/j.nutres.2010.03.004.
   PubMed Web of Science ®Google Scholar
• Farhat, G. N., J. A. Cauley, K. A. Matthews, A. B. Newman, J. Johnston, R. Mackey, and K. Sutton-Tyrrell. 2006. Volumetric BMD and vascular calcification in middle-aged women: The study of womens health across the nation. Journal of Bone and Mineral Research 21 (12):1839–46. doi:10.1359/jbmr.060903.
   PubMed Web of Science ®Google Scholar
• Goff, D. C., D. M. Lloyd-Jones, G. Bennett, S. Coady, R. B. D’Agostino, R. Gibbons, and P. W. Wilson. 2013. 2013 ACC/AHA guideline on the assessment of cardiovascular risk. Circulation 129 (25):Suppl 2.
   Web of Science ®Google Scholar
• Khosla, S., E. J. Atkinson, L. J. Melton, and B. L. Riggs. 1997. Effects of age and estrogen status on serum parathyroid hormone levels and biochemical markers of bone turnover in women: A population-based study1. The Journal of Clinical Endocrinology & Metabolism 82 (5):1522–27.
   PubMed Web of Science ®Google Scholar
• Liu, J., L. Zhu, X. Yang, H. Huang, and D. Ye. 2013. HMG-CoA reductase inhibitors (statins) and bone mineral density: A meta-analysis. Bone 54 (1):151–56. doi:10.1016/j.bone.2013.01.044.
   PubMed Web of Science ®Google Scholar
• Melton, L. J., III, C. S. Crowson, and W. M. O’fallon. 1999. Fracture incidence in Olmsted county, Minnesota: Comparison of urban with rural rates and changes in urban rates over time. Osteoporosis International 9 (1):29–37.
   PubMed Web of Science ®Google Scholar
• Mori, M., T. Nishikawa, K. Masuno, T. Okamura, A. Tanaka, and M. Shikimori. 2010. Statins: Candidates for promoting bone formation via BMP-2. Oral Medicine & Pathology 14:81–87. doi:10.3353/omp.14.81.
   Google Scholar
• Mozaffarian, D., Benjamin, E. J., Go, A. S., Arnett, D. K., Blaha, M. J., Cushman, M., Das SR, de Ferranti S, Després JP, Fullerton HJ, Howard VJ. 2015. Heart disease and stroke statistics–2015 update: A report from the American Heart Association. Circulation 131 (4):329–322.
   Web of Science ®Google Scholar
• Qu, X., X. Huang, F. Jin, H. Wang, Y. Hao, T. Tang, and K. Dai. 2013. Bone mineral density and all-cause, cardiovascular and stroke mortality: A meta-analysis of prospective cohort studies. International Journal of Cardiology 166 (2):385–93. doi:10.1016/j.ijcard.2011.10.114.
   PubMed Web of Science ®Google Scholar
• Rianon, N., C. G. Ambrose, H. Pervin, M. Garcia, S. K. Mama, A. V. Schwartz, B. Lee, and T. Harris. 2017. Long-term use of angiotensin-converting enzyme inhibitors protects against bone loss in African American elderly men. Archives of Osteoporosis 12 (1):94. doi:10.1007/s11657-017-0396-2.
   PubMed Web of Science ®Google Scholar
• Ruan, F., Q. Zheng, and J. Wang. 2012. Mechanisms of bone anabolism regulated by statins. Bioscience Reports 32 (6):511–19. doi:10.1042/BSR20110118.
   PubMed Web of Science ®Google Scholar
• Saraykar, S., V. John, B. Cao, M. Hnatow, C. G. Ambrose, and N. Rianon. 2018. Association of selective serotonin reuptake inhibitors and bone mineral density in elderly women. Journal of Clinical Densitometry 21 (2):193–99. doi:10.1016/j.jocd.2017.05.016.
   PubMed Web of Science ®Google Scholar
• Savarese, G., S. Paolillo, C. D’amore, T. Losco, F. Musella, O. Scala, and P. P. Filardi. 2013. Benefits of statins in elderly subjects without established cardiovascular disease: A meta-analysis. European Heart Journal 34 (Suppl 1):834–834. doi:10.1093/eurheartj/eht308.834.
   Google Scholar
• Seo, S. K., B. H. Yun, E. B. Noe, J. W. Suh, Y. S. Choi, and B. S. Lee. 2015. Decreased bone mineral density is associated with coronary atherosclerosis in healthy postmenopausal women. Obstetrics & Gynecology Science 58 (2):144. doi:10.5468/ogs.2015.58.2.144.
   PubMedGoogle Scholar
• Shepherd, J., G. Blauw, and M. Murphy. 2003. Pravastatin in elderly individuals at risk of vascular disease (PROSPER): A randomized controlled trial. ACC Current Journal Review 12 (2):40. doi:10.1016/S1062-1458(03)00040-0.
   Google Scholar
• Stone, N. J., J. G. Robinson, A. H. Lichtenstein, C. N. Merz, C. B. Blum, R. H. Eckel, and P. W. Wilson. 2013. 2013 ACC/AHA guideline on the treatment of blood cholesterol to reduce atherosclerotic cardiovascular risk in adults. Circulation 129 (25):Suppl. 2.
   Web of Science ®Google Scholar
• Tankó, L. B., C. Christiansen, D. A. Cox, M. J. Geiger, M. A. McNabb, and S. R. Cummings. 2005. Relationship between osteoporosis and cardiovascular disease in postmenopausal women. Journal of Bone and Mineral Research 20:1912–20. doi:10.1359/JBMR.050711.
   PubMed Web of Science ®Google Scholar
• USPSTF (United States Preventive Services Task Force). 2016. Statin use for the primary prevention of cardiovascular disease in adults: US preventive services task force recommendation statement. JAMA 316 (19):1997–2007. doi:10.1001/jama.2016.15450.
   PubMed Web of Science ®Google Scholar
• Varma, R., W. S. Aronow, Y. Basis, T. Singh, K. Kalapatapu, M. B. Weiss, and C. E. Monsen. 2008. Relation of bone mineral density to frequency of coronary heart disease. The American Journal of Cardiology 101 (8):1103–04. doi:10.1016/j.amjcard.2007.12.013.
   PubMed Web of Science ®Google Scholar
• Vassalle, C., and A. Mazzone. 2016. Bone loss and vascular calcification: A bi-directional interplay? Vascular Pharmacology 86:77–86. doi:10.1016/j.vph.2016.07.003.
   PubMed Web of Science ®Google Scholar
• Wenger, N. K. 2003. Coronary heart disease: The female heart is vulnerable. Progress in Cardiovascular Diseases 46:199–229. doi:10.1016/j.pcad.2003.08.003.
   PubMed Web of Science ®Google Scholar
• Wilmot, K. A., A. Khan, S. Krishnan, D. J. Eapen, and L. Sperling. 2014. Statins in the elderly: A patient-focused approach. Clinical Cardiology 38 (1):56–61. doi:10.1002/clc.22338.
   PubMed Web of Science ®Google Scholar
• Xu, R., H. Yang, Y. Li, Q. Wang, A. Guo, A. Ayiti, and Y. Maimti. 2016. Association of coronary artery calcium with bone mineral density in postmenopausal women. Coronary Artery Disease 27 (7):586–91. doi:10.1097/MCA.0000000000000402.
   PubMed Web of Science ®Google Scholar
• Ye, C., M. Xu, S. Wang, S. Jiang, X. Chen, X. Zhou, and R. He. 2016. Decreased bone mineral density is an independent predictor for the development of atherosclerosis: A systematic review and meta-analysis. PLoS One 11 (5):e0154740. doi:10.1371/journal.pone.0154740.
   PubMed Web of Science ®Google Scholar