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Hemoglobin
international journal for hemoglobin research
Volume 30, 2006 - Issue 4
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Original Article

Association of the Methylenetetrahydrofolate Reductase A1298C but not the C677T Single Nucleotide Polymorphism with Sickle Cell Disease in Bahrain

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Pages 449-453 | Received 07 Jan 2006, Accepted 21 Mar 2006, Published online: 07 Jul 2009

REFERENCES

  • Lentz SR. Mechanisms of homocysteine-induced atherothrombosis. J Thromb Haemost 2005; 3(8)1646–1654, [INFOTRIEVE]
  • Quere I, Gris JC, Dauzat M. Homocysteine and venous thrombosis. Semin Vasc Med 2005; 5(2)183–189, [INFOTRIEVE], [CROSSREF]
  • D’Angelo A, Mazzola G, Fermo I. Gene-gene and gene-environment interactions in mild hyperhomocysteinaemia. Pathophysiol Haemost Thromb 2003; 33(5–6)337–341, [CROSSREF]
  • Balasa VV, Gruppo RA, Gartside PS, Kalinyak KA. Correlation of the C677T MTHFR genotype with homocysteine levels in children with sickle cell disease. J Pediatr Hematol Oncol 1999; 21(5)397–400, [INFOTRIEVE], [CROSSREF]
  • Friedman G, Goldschmidt N, Friedlander Y, Ben-Yehuda A, Selhub J, Babaey S, Mendel M, Kidron M, Bar-On H. A common mutation A1298C in human methylene-tetrahydrofolate reductase gene: association with plasma total homocysteine and folate concentrations. J Nutr 1999; 129(9)1656–1661, [INFOTRIEVE]
  • Friso S, Girelli D, Trabetti E, Stranieri C, Olivieri O, Tinazzi E, Martinelli N, Faccini G, Pignatti PF, Corrocher R. A1298C methylenetetrahydrofolate reductase mutation and coronary artery disease: relationships with C677T polymorphism and homocysteine/folate metabolism. Clin Exp Med 2002; 2(1)7–12, [INFOTRIEVE], [CROSSREF]
  • Chui DHK, Dover GJ. Sickle cell disease: no longer a single gene disorder. Curr Opin Pediatr 2001; 13(1)22–27, [INFOTRIEVE], [CROSSREF]
  • Ataga KI, Orringer EP. Hypercoagulability in sickle cell disease: a curious paradox. Am J Med 2003; 115(9)721–728, [INFOTRIEVE], [CROSSREF]
  • Berney SI, Ridler CD, Stephens AD, Thomas AE, Kovacs IB. Enhanced platelet reactivity and hypercoagulability in the steady state of sickle cell anemia. Am J Hematol 1992; 40(4)290–294, [INFOTRIEVE]
  • Papadimitriou CA, Travlou A, Kalos A, Douratsos D, Lali P. Study of platelet function in patients with sickle cell anemia during steady state and vaso-occlusive crisis. Acta Haematol 1993; 89(4)180–183, [INFOTRIEVE]
  • Kirkham FJ, DeBaun MR. Stroke in children with sickle cell disease. Curr Treat Options Neurol 2004; 6(5)357–35, [INFOTRIEVE]
  • Couto FD, Adorno EV, Menezes JF, Moura Neto JP, Rego MA, Reis MG, Gonçalves MS. C677T polymorphism of the MTHFR gene and variant hemoglobins: a study in newborns from Salvador, Bahia, Brazil. Cad Saude Publica 2004; 20(2)529–553, [INFOTRIEVE]
  • Couto FD, Boas WV, Lyra I, Zanette Â, Dupuit MF, Almeida MNT, Reis MG, Souza Gonçalves M. A C677T methylenetetrahydrofolate reductase (MTHFR) polymorphism and G20210A mutation in the prothrombin gene of sickle cell anemia patients from Northeast Brazil. Hemoglobin 2004; 28(3)237–241, [INFOTRIEVE], [CROSSREF]
  • Fawaz NA, Bashawery L, Al-Sheikh I, Qatari A, Al-Othman SS, Almawi WY. Factor V-Leiden, prothrombin G20210A, and MTHFR C677T mutations among patients with sickle cell disease in Eastern Saudi Arabia. Am J Hematol 2004; 76(3)307–309, [INFOTRIEVE], [CROSSREF]
  • Adekile AD, Kutlar F, Haider MZ, Kutlar A. Frequency of the C677T mutation of the methylenetetrahydrofolate reductase gene among Kuwaiti sickle cell disease patients. Am J Hematol 2001; 66(4)263–266, [INFOTRIEVE], [CROSSREF]
  • Sambrook J, Fritsch EF, Maniatis T. Molecular Cloning: A Laboratory Manual, 2nd. Cold Spring Harbor Laboratory Press, Cold Spring Harbor 1989
  • Zezos P, Papaioannou G, Nikolaidis N, Vasiliadis T, Giouleme O, Evgenidis N. Hyperhomocysteinemia in ulcerative colitis is related to folate levels. World J Gastroenterol 2005; 11(38)6038–6042, [INFOTRIEVE]
  • Kutlar A, Kutlar F, Turker I. The methylenetetrahydrofolate reductase (C667T) mutation as a potential risk factor for avascular necrosis in sickle cell disease. Hemoglobin 2001; 25(2)213–217, [INFOTRIEVE], [CROSSREF]
  • Haviv YS, Shpichinetsky V, Goldschmidt N, Atta IA, Ben-Yehuda A, Friedman G. The common mutations C677T and A1298C in the human methylenetetrahydrofolate reductase gene are associated with hyperhomocysteinemia and cardiovascular disease in hemodialysis patients. Nephron 2002; 92(1)120–126, [INFOTRIEVE], [CROSSREF]
  • Volcik KA, Blanton SH, Tyerman GH, Jong ST, Rott EJ, Page TZ, Romaine NK, Northrup H. Methylenetetrahydrofolate reductase and spina bifida: evaluation of level of defect and maternal genotypic risk in Hispanics. Am J Med Genet 2000; 95(1)21–27, [INFOTRIEVE], [CROSSREF]

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