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Hemoglobin
international journal for hemoglobin research
Volume 40, 2016 - Issue 4
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Original Article

Coinheritance of a Rare Nucleotide Substitution on the β-Globin Gene and Other Known Mutations in the Globin Clusters: Management in Genetic Counseling

Margherita VinciguerraDepartment of Hematology and Rare Diseases, Unit of Rare Diseases of Blood and Blood-Forming Organs, Villa Sofia-Cervello Hospital, Palermo, Italy and ;Department of Hematology and Rare Diseases, Unit for Molecular Diagnosis of Rare Diseases, Regional Reference Laboratory for Screening and Prenatal Diagnosis of Hemoglobinopathies, Villa Sofia-Cervello Hospital, Palermo, Italy
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Cristina PassarelloDepartment of Hematology and Rare Diseases, Unit of Rare Diseases of Blood and Blood-Forming Organs, Villa Sofia-Cervello Hospital, Palermo, Italy and ;Department of Hematology and Rare Diseases, Unit for Molecular Diagnosis of Rare Diseases, Regional Reference Laboratory for Screening and Prenatal Diagnosis of Hemoglobinopathies, Villa Sofia-Cervello Hospital, Palermo, Italy
,
Filippo LetoDepartment of Hematology and Rare Diseases, Unit of Rare Diseases of Blood and Blood-Forming Organs, Villa Sofia-Cervello Hospital, Palermo, Italy and ;Department of Hematology and Rare Diseases, Unit for Molecular Diagnosis of Rare Diseases, Regional Reference Laboratory for Screening and Prenatal Diagnosis of Hemoglobinopathies, Villa Sofia-Cervello Hospital, Palermo, Italy
,
Anna CrivelloDepartment of Hematology and Rare Diseases, Unit of Rare Diseases of Blood and Blood-Forming Organs, Villa Sofia-Cervello Hospital, Palermo, Italy and ;Department of Hematology and Rare Diseases, Unit for Molecular Diagnosis of Rare Diseases, Regional Reference Laboratory for Screening and Prenatal Diagnosis of Hemoglobinopathies, Villa Sofia-Cervello Hospital, Palermo, Italy
,
Maria FustaneoDepartment of Hematology and Rare Diseases, Unit of Rare Diseases of Blood and Blood-Forming Organs, Villa Sofia-Cervello Hospital, Palermo, Italy and
,
Filippo CassaràDepartment of Hematology and Rare Diseases, Unit of Rare Diseases of Blood and Blood-Forming Organs, Villa Sofia-Cervello Hospital, Palermo, Italy and ;Department of Hematology and Rare Diseases, Unit for Molecular Diagnosis of Rare Diseases, Regional Reference Laboratory for Screening and Prenatal Diagnosis of Hemoglobinopathies, Villa Sofia-Cervello Hospital, Palermo, Italy
,
Monica CannataDepartment of Hematology and Rare Diseases, Unit of Rare Diseases of Blood and Blood-Forming Organs, Villa Sofia-Cervello Hospital, Palermo, Italy and ;Department of Hematology and Rare Diseases, Unit for Molecular Diagnosis of Rare Diseases, Regional Reference Laboratory for Screening and Prenatal Diagnosis of Hemoglobinopathies, Villa Sofia-Cervello Hospital, Palermo, Italy
,
Aurelio MaggioDepartment of Hematology and Rare Diseases, Unit of Rare Diseases of Blood and Blood-Forming Organs, Villa Sofia-Cervello Hospital, Palermo, Italy and ;Department of Hematology and Rare Diseases, Unit for Molecular Diagnosis of Rare Diseases, Regional Reference Laboratory for Screening and Prenatal Diagnosis of Hemoglobinopathies, Villa Sofia-Cervello Hospital, Palermo, Italy
&
Antonino GiambonaDepartment of Hematology and Rare Diseases, Unit of Rare Diseases of Blood and Blood-Forming Organs, Villa Sofia-Cervello Hospital, Palermo, Italy and ;Department of Hematology and Rare Diseases, Unit for Molecular Diagnosis of Rare Diseases, Regional Reference Laboratory for Screening and Prenatal Diagnosis of Hemoglobinopathies, Villa Sofia-Cervello Hospital, Palermo, ItalyCorrespondence[email protected]
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Pages 231-235 | Received 24 Mar 2016, Accepted 28 Apr 2016, Published online: 03 Jun 2016

References

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