Publication Cover
Hemoglobin
international journal for hemoglobin research
Volume 40, 2016 - Issue 6
228
Views
7
CrossRef citations to date
0
Altmetric
Original Article

Lactate Dehydrogenase: A Marker of the Severity of Vaso-Occlusive Crisis in Children with Sickle Cell Disease Presenting at the Emergency Department

, , , , , & show all
Pages 388-391 | Received 09 Mar 2016, Accepted 01 Dec 2016, Published online: 31 Mar 2017

References

  • Cela E, Cervera A, Heredia DD, et al. Guía de práctica clínica sobre Enfermedad de células falciformes pediátrica. Sociedad Española de Hematología y Oncología Pediátrica (SEHOP); January 2010. Available from: www.SEHOP.org. ISBN 978-84-694-4619-5.
  • Gill FM, Sleeper LA, Weiner SJ, et al. Clinical events in the first decade in a cohort of infants with sickle cell disease. Cooperative Study of Sickle Cell Disease. Blood. 1995;86(2):776–783.
  • Darbari DS, Onyekwere O, Nouraie M, et al. Markers of severe vaso-occlusive painful episode frequency in children and adolescents with sickle cell anemia. J Pediatr. 2012;160(2):286–290.
  • Platt OS, Thorington BD, Brambilla DJ, et al. Pain in sickle cell disease. Rates and risk factors. N Engl J Med. 1991;325(1):11–16.
  • Darbari DS, Wang Z, Kwak M, et al. Severe painful vaso-occlusive crises and mortality in a contemporary adult sickle cell anemia cohort study. PLoS One. 2013;8:e79923. doi: 10.1371/journal.pone.0079923.
  • Stankovic Stojanovic K, Steichen O, Lefevre G, et al. High lactate dehydrogenase levels at admission for painful vaso-occlusive crisis is associated with severe outcome in adult SCD patients. Clin Biochem. 2012;45(18):1578–1582.
  • Najim OA, Hassan MK. Lactate dehydrogenase and severity of pain in children with sickle cell disease. Acta Haematol. 2011;126(3):157–162.
  • Neely CL, Wajima T, Kraus AP, et al. Lactic acid dehydrogenase activity and plasma hemoglobin elevations in sickle cell disease. Am J Clin Pathol. 1969;52(2):167–169.
  • Kato GJ, McGowan V, Machado RF, et al. Lactate dehydrogenase as a biomarker of hemolysis-associated nitric oxide resistance, priapism, leg ulceration, pulmonary hypertension, and death in patients with sickle cell disease. Blood. 2006;107(6):2279–2285.
  • Taylor JG, 6th, Nolan VG, Mendelsohn L, et al. Chronic hyper-hemolysis in sickle cell anemia: association of vascular complications and mortality with less frequent vasoocclusive pain. PLoS One. 2008;3:e2095. doi: 10.1271/journal.pone.0002095.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.