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Hemoglobin
international journal for hemoglobin research
Volume 41, 2017 - Issue 2
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Short Communication

Hb Southampton [β106(G8)Leu→Pro; HBB: c.320T>C] and Codons 41/42 (–TTCT; HBB: c.124_127delTTCT) in a Chinese Girl

Jiaodi LiuDepartment of Hematology, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, People’s Republic of ChinaView further author information
,
Yumei HuangDepartment of Hematology, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, People’s Republic of ChinaView further author information
,
Yu LeiDepartment of Hematology, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, People’s Republic of ChinaView further author information
&
Yongrong LaiDepartment of Hematology, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, People’s Republic of ChinaCorrespondence[email protected]
View further author information
Pages 134-136 | Received 09 Jan 2017, Accepted 13 Mar 2017, Published online: 05 Jun 2017

References

  • Hyde RD, Hall MD, Wiltshire BG, et al. Haemoglobin Southampton, 106(G8)Leu→Pro: an unstable variant producing severe haemolysis. Lancet. 1972;2(7788):1170–1172.
  • Koler RD, Jones RT, Bigley RH, et al. Hemoglobin Casper: β106(G8)Leu→Pro; a contemporary mutation. Am J Med. 1973;55:549–558.
  • Didkovskii NA, Idel’son LI, Filippova AV, et al. A new case of the unstable Hemoglobin Southampton-Casper (β106) (G68) leucine→proline). [Russian] Probl Gematol Pereliv Krovi. 1976;21(6):48–50.
  • Heintz NH, Howard PL. Hemoglobin Southampton (Casper): characterization of the base mutation. Am J Hematol. 1989;30(1):1–3.
  • Eandi Eberle S, Noguera NI, Sciuccati G, et al. Hb Southampton [β106(G8)Leu→Pro, CTG→CCG] in an Argentinean boy. Hemoglobin. 2006;30(3):401–403.
  • Pereira JA, Lopez P, Costa FF, et al. Hb Southampton [β106(G8)Leu→Pro, CTG→CCG] in a Uruguayan woman. Rev Bras Hematol Hemoter. 2013;35(2):146–147.
  • Costandi AJ, Mahmoud M. Unexpected falsely low pulse oximeter measurements in a child with Hemoglobin Southampton. J Clin Anesth. 2016;33:320–321.
  • Dacie JV, Lewis S. Practical haematology. 8th ed. New York (NY): Churchill Livingstone; 1995.
  • Wajcman H, Gacon G, Labie D, et al. Isolation and functional characterization of Hemoglobin Casper: β106(G8)Leu→Pro. Biochemistry. 1975;14(22):5017–5020.

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