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Hemoglobin
international journal for hemoglobin research
Volume 41, 2017 - Issue 3
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Short Communication

Hematological and Molecular Characterization of a Novel Hb A2 Variant with Homozygous α-Thalassemia-2 in a Southern Thai Individual

ORCID Icon, , , &
Pages 213-215 | Received 17 May 2017, Accepted 14 Jun 2017, Published online: 10 Aug 2017

References

  • Steinberg MH, Adams JG, 3rd. Hemoglobin A2: origin, evolution, and aftermath. Blood. 1991;78(9):2165–2177.
  • Mosca A, Paleari R, Ivaldi G, et al. The role of Haemoglobin A2 testing in the diagnosis of thalassaemias and related haemoglobinopathies. J Clin Path. 2009;62(1):13–17.
  • Bouva M, Harteveld C, van Delft P, Giordano P. Known and new δ globin gene mutations and their diagnostic significance. Haematologica. 2006;91(1):129–132.
  • Giardine B, Borg J, Viennas E, et al. Updates of the HbVar database of human hemoglobin variants and thalassemia mutations. Nucleic Acids Res. 2014;42(Database issue):D1063–1069 (http://globin.cse.psu.edu).
  • Chaibunruang A, Fucharoen G, Fucharoen S. First description of a Hb A2 variant in Thailand. Identification of Hb A2-Melbourne [δ43(CD2)Glu→Lys] in Thai individuals. Hemoglobin. 2012;36(1):80–84.
  • Panyasai S, Fucharoen G, Fucharoen S. Known and new Hemoglobin A2 variants in Thailand and implication for β-thalassemia screening. Clin Chim Acta. 2015;438(1):226–230.
  • Chong SS, Boehm CD, Cutting GR, Higgs DR. Simplified multiplex-PCR diagnosis of common Southeast Asian deletional determinants of α-thalassemia. Clin Chem. 2000;46(10):1692–1695.
  • Honig GR, Adams JG III. Human Hemoglobin Genetics. Vienna, Austria: Springer-Verlag, 1986.
  • Spivak VA, Molchanova TP, Postnikov YuV, et al. A new abnormal hemoglobin: Hb Mozhaisk β92(F8)HIS→ARG. Hemoglobin. 1982;6(2):169–181.
  • Murata K, Yamamoto S, Hirano Y, et al. First Japanese family with the unstable Hemoglobin Zürich [β63(E7)His→Arg]. Jap J Med. 1982;21(1):40–45.
  • Patterson M, Walker L, Chui DHK, et al. Identification of a new hemoglobin variant: Hb St. Joseph’s [β77(EF1)His→Leu]. Hemoglobin. 2003;27(3):181–183.
  • Hopmeier P, Plaseska-Karanfilska D, Efremov GD. A new β chain variant, Hb Vienna or β77(EF1)His→Gln. Hemoglobin. 1998;22(4):391–395.
  • Hidaka K, Iuchi I, Miyake K, et al. Hb Fukuyama [β77(EF1)His→Tyr]: a new abnormal hemoglobin discovered in a Japanese. Hemoglobin. 1988;12(4):391–394.
  • Arcasoy A, Turhanoglu I, Gozdasoglu S, Ogur G. First observation of Hemoglobin J-Iran [β77(EF1)His→Asp] in Turkey. Hemoglobin. 1986;10(2):209–213.

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