First Report of Hb Kent [β37(C3)Trp→Cys (TGG>TGC) HBB: c.114G>C] in a Chinese Family

Nelson C.N. ChanDepartment of Anatomical and Cellular Pathology (Haematology), Prince of Wales Hospital, Shatin, New Territories, Hong Kong SAR, People’s Republic of China; Correspondence[email protected]

http://orcid.org/0000-0002-8770-5438

King-Ho ChowDepartment of Family Medicine, Prince of Wales Hospital, Shatin, New Territories, Hong Kong SAR, People’s Republic of China;

Rico F.Y. LeungDepartment of Anatomical and Cellular Pathology (Haematology), Prince of Wales Hospital, Shatin, New Territories, Hong Kong SAR, People’s Republic of China;

Sequence S.H. TangDepartment of Anatomical and Cellular Pathology (Haematology), Prince of Wales Hospital, Shatin, New Territories, Hong Kong SAR, People’s Republic of China;

Michelle F.W. ChiuDepartment of Anatomical and Cellular Pathology (Haematology), Prince of Wales Hospital, Shatin, New Territories, Hong Kong SAR, People’s Republic of China;

Rosalind LieDepartment of Anatomical and Cellular Pathology (Haematology), Prince of Wales Hospital, Shatin, New Territories, Hong Kong SAR, People’s Republic of China;

Kelvin C.K. ChengDepartment of Anatomical and Cellular Pathology (Haematology), Prince of Wales Hospital, Shatin, New Territories, Hong Kong SAR, People’s Republic of China;

Kin-Mang LauDepartment of Anatomical and Cellular Pathology (Haematology), Faculty of Medicine, The Chinese University of Hong Kong Shatin, New Territories, Hong Kong SAR, People’s Republic of China

Natalie P.H. ChanDepartment of Anatomical and Cellular Pathology (Haematology), Prince of Wales Hospital, Shatin, New Territories, Hong Kong SAR, People’s Republic of China;

Margaret H.L. NgDepartment of Anatomical and Cellular Pathology (Haematology), Faculty of Medicine, The Chinese University of Hong Kong Shatin, New Territories, Hong Kong SAR, People’s Republic of China

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References

Hoyer JD, Kaur P, Kozak EA, et al. Five variants of the β-globin gene without clinical or hematological effects: Hb Maryland [β47(CD6)Asp→His], Hb Kent [β37(C3)Trp→Cys], Hb Visayan [β136(H14)Gly→Cys], Hb Cutlerville [β138(H16)Ala→Val] and Hb Hornchurch [β43(CD2)Glu→Lys]. Hemoglobin. 2008;32(5):471–477.
PubMed Web of Science ®Google Scholar
Brennan SO, King RI, Florkowski CM. β37Trp→Cys mutation leads to multiple new hemoglobin species in red cells. Clin Biochem. 2012;45(3):259–263.
PubMed Web of Science ®Google Scholar
Liu YT, Old JM, Miles K, et al. Rapid detection of α-thalassaemia deletions and α-globin gene triplication by multiplex polymerase chain reactions. Br J Haematol. 2000;108(2):295–299.
PubMed Web of Science ®Google Scholar
Lau YL, Chan LC, Chan YY, et al. Prevalence and genotypes of α- and β-thalassemia carriers in Hong Kong – implications for population screening. N Engl J Med. 1997;336(18):1298–1301.
PubMed Web of Science ®Google Scholar

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First Report of Hb Kent [β37(C3)Trp→Cys (TGG>TGC) HBB: c.114G>C] in a Chinese Family

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First Report of Hb Kent [β37(C3)Trp→Cys (TGG>TGC) HBB: c.114G>C] in a Chinese Family

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