Publication Cover
Hemoglobin
international journal for hemoglobin research
Volume 45, 2021 - Issue 2
157
Views
7
CrossRef citations to date
0
Altmetric
Original Articles

Hb Bart’s Hydrops Fetalis Syndrome and Hb H Disease Caused by Deletional Chiang Rai (– –CR) α0-Thalassemia in Two Unrelated Thai Families

, ORCID Icon, &
Pages 75-79 | Received 10 Nov 2020, Accepted 09 Mar 2021, Published online: 06 Apr 2021

References

  • Harteveld CL, Higgs DR. Alpha-thalassaemia. Orphanet J Rare Dis. 2010;5(1):13.
  • Higgs DR, Vickers MA, Wilkie AOM, et al. A review of the molecular genetics of the human alpha-globin gene cluster. Blood. 1989;73(5):1081–1104.
  • Fischel-Ghodsian N, Vickers MA, Seip M, et al. Characterization of two deletions that remove the entire human zeta-alpha globin gene complex (– –THAI and – –FIL). Br J Haematol. 1988;70(2):233–238.
  • Fucharoen G, Fucharoen S, Wanhakit C, et al. Molecular basis of alpha0-thalassemia in northeast of Thailand. Southeast Asian J Trop Med Public Health. 1995;26(Suppl 1):249–251.
  • Winichagoon P, Higgs DR, Goodbourn SE, et al. The molecular basis of alpha-thalassaemia in Thailand. EMBO J. 1984;3(8):1813–1818.
  • Liang ST, Wong VC, So WW, et al. Homozygous alpha-thalassaemia: clinical presentation, diagnosis and management: a review of 46 cases. Br J Obstet Gynaecol. 1985;92(7):680–684.
  • Thumasathit B, Nondasuta A, Silpisornkosol S, et al. Hydrops fetalis associated with Bart’s hemoglobin in northern Thailand. J Pediatr. 1968;73(1):132–138.
  • Fucharoen S, Viprakasit V. Hb H disease: clinical course and disease modifiers. Hematology Am Soc Hematol Educ Program. 2009;26–34.
  • Laosombat V, Viprakasit V, Chotsampancharoen T, et al. Clinical features and molecular analysis in Thai patients with HbH disease. Ann Hematol. 2009;88(12):1185–1192.
  • Ruengdit C, Panyasai S, Kunyanone N, et al. Characterization and identification of Hb Bart’s hydrops fetalis caused by a compound heterozygous mutation – SEA/– CR , a novel α0-thalassemia deletion. Int J Lab Hematol. 2020;42(3):e116–e120.
  • Fucharoen S, Fucharoen G, Sanchaisuriya K, et al. Molecular analysis of a Thai beta-thalassaemia heterozygote with normal haemoglobin A2 level: implication for population screening. Ann Clin Biochem. 2002;39(Pt 1):44–49.
  • Pornprasert S, Phusua A, Suanta S, et al. Detection of alpha-thalassemia-1 Southeast Asian type using real-time gap-PCR with SYBR Green1 and high resolution melting analysis. Eur J Haematol. 2008;80(6):510–514.
  • Pornprasert S, Wiengkum T, Srithep S, et al. Detection of α-thalassemia-1 Southeast Asian and Thai type deletions and β-thalassemia 3.5-kb deletion by single-tube multiplex real-time PCR with SYBR Green1 and high-resolution melting analysis. Korean J Lab Med. 2011;31(3):138–142.
  • Chui DHK, Fucharoen S, Chan V. Hemoglobin H disease: not necessarily a benign disorder. Blood. 2003;101(3):791–800.
  • He S, Li J, Huang P, et al. Characterization of Hb Bart’s hydrops fetalis caused by – –SEA and a large Novel α0-thalassemia deletion. Hemoglobin. 2018;42(1):61–64.
  • Yang Y, Li D-Z. Early onset of fetal hydrops associated with the α-thalassemia – –THAI deletion. Hemoglobin. 2014;38(6):431–434.
  • Charoenkwan P, Taweephon R, Sae-Tung R, et al. Molecular and clinical features of Hb H disease in northern Thailand. Hemoglobin. 2005;29(2):133–140.
  • Pornprasert S, Salaeh N-A, Tookjai M, et al. Hematological analysis in Thai samples with deletional and nondeletional HbH diseases. Lab Med. 2018;49(2):154–159.
  • Surapolchai P, Chuansumrit A, Sirachainan N, et al. A molecular study on the role of alpha-hemoglobin-stabilizing protein in hemoglobin H disease. Ann Hematol. 2017;96(6):1005–1014.
  • Velasco-Rodríguez D, Blas C, Alonso-Domínguez J-M, et al. Cut-off values of hematologic parameters to predict the number of alpha genes deleted in subjects with deletional alpha thalassemia. Int J Mol Sci. 2017;18(12):2707.
  • Viprakasit V, Tanphaichitr VS. Compound heterozygosity for α0-thalassemia (– –THAI) and Hb constant spring causes severe Hb H disease. Hemoglobin. 2002;26(2):155–162.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.