Thalassemia in Malaysia

References

• Department of Statistics Malaysia, Official Portal. Demographic Statistics Second Quarter 2019. Malaysia [Online] [cited 2019 Sep 17] Available from: https://www.dosm.gov.my.
   Google Scholar
• United Nations – World Population Prospects 2019). Malaysia Birth Rate 1950–2019 [Online]. [cited 2019 Sep 14]. Available from: https://population.un.org/wpp/Download/Standard/Population.
   Google Scholar
• Dato’ Sri Dr. Mohd Uzir Mahidin, Vital Statistics, Malaysia, Department of Statistics, Malaysia, 2018. [Online]. [cited 2019 Oct 2]. Available from: https://www.dosm.gov.my/v1/.
   Google Scholar
• Chen G. Vital to know risks involved ahead of time. The Star Online 2019. [cited 2019 Sep 16] Available from: https://www.thesta.com.my/metro-news/2019/03/23/vital-to-know-risks-involved-ahead-of-time.
   Google Scholar
• Malaysia ranks 1st in world’s best healthcare category [Online]. [cited 2019 Sep 12]. Available from: https://www.thestar.com.my/news/nation/2019/02/07/malaysia-ranks-1st/in-worlds-best-healthcare-category.
   Google Scholar
• Yeoh T. Healthcare Resource Guide: Malaysia 2019 [Online]. [cited 2019 Sep 19]. Available from: https://2016.export.gov/industry/health/healthcareresourceguide/eg_main_108601.asp.
   Google Scholar
• Britnell M. Part 1: Asia and Australia. Malaysia – Reform some time soon?. In Search of the Perfect Health System. 1st ed. London (UK): Palgrave Macmillan Publishers Ltd. 2015. 27. ISBN: 978-1-137-49661-4.
   Google Scholar
• 6 Things you should know about healthcare in Malaysia [Online]. [cited 2019 Sep 17]. Available from: https://www.aia.com.my/en/what-matters/health/wellness/healthcare-in-malaysia.html.
   Google Scholar
• Onn LP. What Lies Ahead for Malaysian Healthcare? ISEAS – Yusof Ishak Institute, 2015. [Online]. [cited 2019 Sep 16]. Available from: http://hdl.handle.net/11540/6715.
   Google Scholar
• Teck CH, Ho CJC. Financing universal coverage in Malaysia: a case study. BMG Public Health. 2012;12(Suppl 1):S7–S7.
   PubMed Web of Science ®Google Scholar
• Lan WS. Management of thalasaemia. Health Technology Assesment Unit, Medical Development Division, Ministry of Health Malaysia. 2003;3:137.
   Google Scholar
• Pauzy LHM, Esa E, Mokhri NM, et al. Thalassemia distribution based on screening programs in the population of the East Malaysian State of Sabah. J Blood Disord Transfus. 2018;9(1):395–398.
   Google Scholar
• Ishak AR. 8,042 pesakit talasemia di Malaysia. Berita Harian [Online]. Available from: https://bharian.com.my/berita/nasiona/2019/05/560238/8042-pesakit-tlasemia-di-malaysia.
   Google Scholar
• George E. Thalassaemia: a public health problem in Malaysia. In: George E, Editor. Thalassaemia Carrier Diagnosis in Malaysia. Kuala Lumpur (Malaysia): SP-Muda Printing Sdn Bhd; 1998. p. 1–6.
   Google Scholar
• George E. β-Thalassemia major in Malaysia, an on-going public health problem. Med J Malaysia. 2001;56(4):397–400.
   PubMedGoogle Scholar
• Tan J, George E, Tan K, et al. Molecular defects in the beta-globin gene identified in different ethnic groups/populations during prenatal diagnosis for beta-thalassemia: a Malaysian experience. Clin Exp Med. 2004;4(3):142–147.
   PubMed Web of Science ®Google Scholar
• Ahmad R, Saleem M, Aloysious NS, et al. Distribution of alpha thalassaemia gene variants in diverse ethnic populations in malaysia: data from the institute for medical research. Int J Mol Sci. 2013;14(9):18599–18614.
   PubMed Web of Science ®Google Scholar
• Weatherall DJ, Clegg JB. Inherited haemoglobin disorders: an increasing global health problem. Bull World Health Organ. 2001;79(8):704–711.
   PubMed Web of Science ®Google Scholar
• Tam S. RM 40 mil to treat 600,000 victims of thalassaemia. The Star Online. [cited 2019 Oct 10]. Available from: www.thestar.com.my/news/nation/2005/03/04.rm40mil-to-treat-600000-victims-of-thalassaemia.
   Google Scholar
• Ministry of Health Malaysia. Edition MOH, Malaysia. Management of Transfusion Dependent Thalassaemia. Putrajaya (Malaysia): Medical Development Division Health Technology Assessment Unit. 2009. p. 1–130.
   Google Scholar
• Ngim CF, Lai NM, Ibrahim H, et al. Attitudes towards prenatal diagnosis and abortion in a multi-ethnic country: a survey among parents of children with thalassaemia major in Malaysia. J Community Genet. 2013;4(2):215–221.
   PubMedGoogle Scholar
• Ngim CF, Lai NM, Ibrahim H. Counseling for prenatal diagnosis and termination of pregnancy due to thalassemia major: a survey of health care workers’ practices in Malaysia. Prenat Diagn. 2013;33(13):1226–1232.
   PubMed Web of Science ®Google Scholar
• Ministry of Health Malaysia. Edition MOH, Malaysia. Executive Summary. Management of Thalassaemia. Putraya (Malaysia): Health Technology Assessment Unit, Medical Development Division, Ministry of Health Malaysia; 2006. p. 1–3. Available from: https://www.moh.gov/my/moh/resources/auto%20download%20images/587f136d4ae96.pdf
   Google Scholar
• Ministry of Health Malaysia. 4th ed. MOH, Malaysia. Malaysian Guideline for Good Clinical Practice. Putraya (Malaysia). Petang Jaya (Selangor, Malaysia): National Committee for Clinical Research (NCCR); National Pharmaceutical Regulatory Agency (NPRA); 2018. p. 1–76.
   Google Scholar
• Tan J-A, Lee P-C, Wee Y-C, et al. High prevalence of α- and β-thalassemia in the Kadazandusuns in East Malaysia: challenges in providing effective health care for an indigenous group. J Biomed Biotechnol. 2010;2010:706872.
   PubMedGoogle Scholar
• Jameela S, Sabirah SO, Babam J, et al. Thalassemia screening among students in a secondary school in Ampang, Malaysia. Med J Malaysia. 2011;66(5):522–524.
   PubMedGoogle Scholar
• Ong CK, Lim SL, Tan WC, et al. Endocrine complications in transfusion dependent thalassemia in Penang Hospital. Med J Malaysia. 2008;63(2):109–112.
   PubMedGoogle Scholar
• Jamal R, Baizura J, Hamidah A, et al. Abnormalities in lung function among multiply-transfused thalassemia patients: results from a thalassemia center in Malaysia. Southeast Asian J Trop Med Public Health. 2005;36(1):265–269.
   PubMedGoogle Scholar
• Ismail A, Campbell MJ, Ibrahim HM, et al. Health related quality of life in Malaysian children with thalassaemia. Health Qual Life Outcomes. 2006;4:39.
   PubMed Web of Science ®Google Scholar
• Ainoon O, Cheong SK. Thalassaemia in Malaysia: a strategy for prevention. Malays J Pathol. 1994;16(1):23–27.
   PubMedGoogle Scholar
• Teh LK, George E, Lai MI, et al. Molecular basis of transfusion dependent beta-thalassemia major patients in Sabah. J Hum Genet. 2014;59(3):119–123.
   PubMed Web of Science ®Google Scholar
• Symaco LP. 2015. Perspectives on practice and policy: success increasing access and retention in primary education in Malaysia. Report of Educate a Child: Malaysia [Online]. [cited 2019 Oct 2]. Available from: https://www.unicef.org>malaysia>media>file.
   Google Scholar
• Frankham R. Genetic adaptation to captivity in species conservation programs. Mol Ecol. 2008;17(1):325–333.
   PubMed Web of Science ®Google Scholar
• Syperman N, Murali RSN, Lee P. Li impressed with Malacca’s racial diversity and cendol. The Star Online. [cited 2019 Sep 19]. Available from: http://www.thestar.com.my/search/?q=Li+impressed+with+Malacca%E2%80%99s+racial+diversity+cendol&qsort=newest&qrec=10&qstockcode.
   Google Scholar
• Patrinos GP, Giardine B, Riemer C, et al. Improvements in the HbVar database of human hemoglobin variants and thalassemia mutations for population and sequence variation studies. Nucleic Acids Res. 2004;42(Database issue):D537–554.
   Web of Science ®Google Scholar
• Ahmad R, Sabrina N, Bahrin S, et al. Distribution of α thalassaemia in 16 year old Malaysian students in Penang, Melaka and Sabah. Med J Malaysia. 2012;67(6):565–570.
   PubMedGoogle Scholar
• Buang SN, Rashid D, Jaafar S, et al. A review on thalassemia profile in Malaysia and the challenges of its prevention and control programme. Malaysian J Public Health Med. 2017;17(2):15–26.
   Google Scholar
• Rosnah B, Rosline H, Wan Zaidah AW, et al. Detection of common deletional alpha-thalassemia spectrum by molecular technique in Kelantan, Northeastern Malaysia. ISRN Hematol. 2012;2012:462969.
   PubMedGoogle Scholar
• Wee Y-C, Tan K-L, Chow TW-P, et al. Heterogeneity in alpha-thalassemia interactions in Malays, Chinese and Indians in Malaysia. J Obstet Gynaecol Res. 2005;31(6):540–546.
   PubMed Web of Science ®Google Scholar
• Hassan S, Ahmad R, Zakaria Z, et al. Detection of β-globin gene mutations among β-thalassaemia carriers and patients in Malaysia: application of multiplex amplification refractory mutation system-polymerase chain reaction. Malaysian J Med Sci. 2013;20(1):13–30.
   Google Scholar
• Li Z, Li F, Li M, et al. The prevalence and spectrum of thalassemia in Shenzhen, Guangdong Province, People's Republic of China. Hemoglobin. 2006;30(1):9–14.
   PubMed Web of Science ®Google Scholar
• Abdullah WA, Jamaluddin NB, Kham SK, et al. The spectrum of beta-thalassemia in Malays in Singapore and Kelantan. Southeast Asian J Trop Med Public Health. 1996;27(1):163–168.
   Google Scholar
• Fucharoen S, Winichagoon P. Haemoglobinopathies in southeast Asia. Indian J Med Res. 2011;134(4):498–506.
   PubMedGoogle Scholar
• Teh AKH, Chan LL. Fifth report of the national transplant registry 2008. In: Hooi LS, Manor LY, Editors. Kuala Lumpur 2010. Ministry of Health Malaysia. [Online]. Available from: http:/www.mst.org.my/ntrSite.
   Google Scholar
• Bal P, Shamsir S, Warid N, et al. Health application: mobile thalassemia patient application. Presented at the Industrial Electronics and Applications (IEEE) and Biomedical Engineering and Sciences (IECBES) Conference; 2014 Dec 8–10; Miri, Sarawak, Malaysia. USA: IEEE, Institute of Electrical and Electronics Engineers; 2014. p. 792–796.
   Google Scholar
• Jamal R, Fadzillah G, Zulkifli SZ, et al. Seroprevalence of hepatitis B, hepatitis C, CMV and HIV in multiply transfused thalassemia patients: results from a thalassemia day care center in Malaysia. Southeast Asian J Trop Med Public Health. 1998;29(4):792–794.
   PubMedGoogle Scholar
• Pedram M, Zandian K, Keikhaie B, et al. A report on chelating therapy and patient compliance by determination of serum ferritin levels in 243 thalassemia major patients. Iranian J Pediatr Soc. 2010;2(2):65–69.
   Google Scholar
• Nadarajan VS. Modern management of thalassemia. ISBT Sci Series. 2011;6(2):432–437.
   Google Scholar
• Ibrahim HM. The Malaysian National Thalassaemia Prevention and Control Programme. Thalassemia report 1st Pan-Asian Conference on Haemoglobinopathies held at Bangkok. Thailand, on February 8-10 2012. 2015 Programme Book.
   Google Scholar
• Dahlui M, Hishamshah MI, Rahman AJA, et al. Quality of life in transfusion-dependent thalassaemia patients on desferrioxamine treatment. Singapore Med J. 2009;50(8):794–799.
   PubMed Web of Science ®Google Scholar
• Sulaiman LH. Thalassemia in Malaysia: current initiatives and future strategies. 7th National Thalassemia Seminar, 2015, held at the Sunway Putra Hotel, Kuala Lumpor, Malaysia on August 8–9 2015.
   Google Scholar
• Wong LP, George E, Tan J-A. Public perceptions and attitudes toward thalassemia: Influencing factors in a multi racial population. BMC Public Health. 2011;11(1):193.
   PubMed Web of Science ®Google Scholar
• Ngim CF, Ibrahim H, Abdullah N, et al. A web-based educational intervention module to improve knowledge and attitudes towards thalassaemia prevention in Malaysian young adults. Med J Malaysia. 2019;74(3):219–225.
   PubMedGoogle Scholar
• Kukreja A, Khan A, Xian L, et al. Awareness of thalassaemia among rural folks in Penang, Malaysia. Internet J Health. 2009;12(1):1–8.
   Google Scholar
• Wong LP, George E, Tan JA. A holistic approach to education programs in thalassemia for a multi-ethnic population: consideration of perspectives, attitudes, and perceived needs. J Community Genet. 2011;2(2):71–79.
   PubMedGoogle Scholar
• Ngim CF, Ibrahim H, Lai NM, et al. A single centre study on birth of children with transfusion-dependent thalassaemia in Malaysia and reasons for ineffective prevention. Prenat Diagn. 2015;35(1):51–59.
   PubMed Web of Science ®Google Scholar
• Eleftheriou A. Health Education. In: Old J, Angastiniotis M, Eleftheriou A,., Editors. Prevention of Thalassaemias and Other Haemoglobin Disorders. Vol. 1, 2nd ed. Nicosia (Cyprus): Thalassaemia International Federation. 2013. p. 24–30.
   Google Scholar
• Tu HT, Cohen GR. Striking jump in consumers seeking health care information. Track Rep. 2008;20:1–8.
   Google Scholar
• Edejer TT. Disseminating health information in developing countries: the role of the internet. BMJ. 2000;321(7264):797–800.
   PubMed Web of Science ®Google Scholar
• Horvath KJ, Ecklund AM, Hunt SL, et al. Developing internet-based health interventions: a guide for public health researchers and practitioners. J Med Internet Res. 2015;17(1):e28.
   PubMed Web of Science ®Google Scholar
• Luan Eng LI, Hie JB. Hydrops foetalis with a fast-moving haemoglobin. Br Med J. 1960;2(5213):1649–1650.
   PubMed Web of Science ®Google Scholar
• Weatherall DJ, Vella F. Thalassaemia in a Gurkha family. Br Med J. 1960;1(5187):1711–1713.
   PubMed Web of Science ®Google Scholar
• Lie-Injo LE. Alpha-chain thalassemia and hydrops fetalis in Malaya: report of five cases. Blood. 1962;20:581–590.
   PubMed Web of Science ®Google Scholar