Advanced search
Publication Cover
Hemoglobin
international journal for hemoglobin research
Volume 46, 2022 - Issue 3
Submit an article Journal homepage
59
Views
0
CrossRef citations to date
0
Altmetric
Short Communications

Hb Laibin [β96(FG3)Leu→Arg; HBB: c.290T>G]: A Novel Hemoglobin Variant Described in a Chinese Family

Yuan-Yuan Huanga Department of Clinical Laboratory, Women and Children Care Hospital of Laibin, Laibin, Guangxi Zhuang Autonomous Region, Laibin, People’s Republic of ChinaView further author information
,
Jun Huanga Department of Clinical Laboratory, Women and Children Care Hospital of Laibin, Laibin, Guangxi Zhuang Autonomous Region, Laibin, People’s Republic of ChinaView further author information
,
Li-Hua Yea Department of Clinical Laboratory, Women and Children Care Hospital of Laibin, Laibin, Guangxi Zhuang Autonomous Region, Laibin, People’s Republic of ChinaView further author information
,
Liang Liangb Center for Medical Genetics and Prenatal Diagnosis, People’s Hospital of Guangxi Zhuang Autonomous Region, Nanning, People’s Republic of ChinaView further author information
&
You-Qiong Lib Center for Medical Genetics and Prenatal Diagnosis, People’s Hospital of Guangxi Zhuang Autonomous Region, Nanning, People’s Republic of ChinaCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0002-8640-7375View further author information
ORCID Icon
Pages 187-190 | Received 16 Dec 2021, Accepted 15 Mar 2022, Published online: 26 May 2022

References

  • Ghosh K, Ghosh K, Agrawal R, Nadkarni AH. Recent advances in screening and diagnosis of hemoglobinopathy. Expert Rev Hematol. 2020;13(1):13–21.
  • Achour A, Koopmann TT, Baas F, Harteveld CL. The evolving role of next-generation sequencing in screening and diagnosis of hemoglobinopathies. Front Physiol. 2021;12:686689.
  • Xiong F, Sun M, Zhang X, et al. Molecular epidemiological survey of haemoglobinopathies in the Guangxi Zhuang Autonomous Region of southern China. Clin Genet. 2010;78(2):139–148.
  • Zhao L-Y, Lin Q-F, He X-W, et al. Hb Hezhou [β64(E8)Gly→Ser; HBB: c.193G>A]: a novel variant on the β-globin gene. Hemoglobin. 2021;45(2):133–135.
  • Li Y-Q, Li Y-W, Liang L, et al. First detection of Hb Cenxi [β46(CD5)Gly→Arg (GGG>CGG), HBB: c.139G>C] by capillary electrophoresis. Hemoglobin. 2021;45(4):262–264.
  • Devaraj R, Wilson JB, Huisman THJ. Hb Regina or α2β296(FG3)Leu→Val: a high oxygen affinity variant discovered by cation-exchange HPLC. Am J Hematol. 1985;19(2):195–200.
  • Lacan P, Kister J, Francina A, et al. Hemoglobin Debrousse (β96[FG3]Leu→Pro): a new unstable hemoglobin with twofold increased oxygen affinity. Am J Hematol. 1996;51(4):276–281.
  • Khongthai K, Ruengdit C, Panyasai S, Pornprasert S. Analysis of deletional Hb H diseases in samples with Hb A2-Hb H and Hb A2-Hb Bart’s on capillary electrophoresis. Hemoglobin. 2019;43(4–5):245–248.
  • Higgins T, Mack M, Khajuria A. Comparison of two methods for the quantification and identification of hemoglobin variants. Clin Biochem. 2009;42(7–8):701–705.
  • Degandt S, Coens R, Cauwelier B, et al. Evaluation of four hemoglobin separation analyzers for hemoglobinopathy diagnosis. J Clin Lab Anal. 2018;32(1):e22224.
  • Xu A, Lei J, Li J, et al. Hb Hunan and Hb Hengyang: two unexpected discoveries during HbA1c measurements. Clin Chem Lab Med. 2019;57(8):e196–e198.
  • Xu A, Chen W, Xie W, et al. A new α chain variant, Hb Heilongjiang (HBA2: c.49A>C), found during Hb A1c measurements. Hemoglobin. 2020;44(2):143–145.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.