Publication Cover
Hemoglobin
international journal for hemoglobin research
Volume 46, 2022 - Issue 6
85
Views
0
CrossRef citations to date
0
Altmetric
Brief Reports

Severe Hb H Disease Caused by Hb Zürich–Albisrieden (HBA1: c.178G>C): Another Case Report

, , , &
Pages 341-343 | Received 15 Nov 2022, Accepted 22 Dec 2022, Published online: 23 Feb 2023

References

  • Piel FB, Weatherall DJ. The α-thalassemias. N Engl J Med. 2014;371(20):1908–1916.
  • Jiang F, Xu LL, Chen GL, et al. Hematological characteristics of Hb Constant Spring (HBA2: c.427T>C) carriers in mainland China. Hemoglobin. 2020;44(2):86–88.
  • Chui DHK, Fucharoen S, Chan V. Hemoglobin H disease: not necessarily a benign disorder. Blood. 2003;101(3):791–800.
  • Dutly F, Fehr J, Goede JS, et al. A new highly unstable α chain variant causing α+-thalassemia: Hb Zurich Albisrieden [α59(E8)Gly→Arg(α2)]. Hemoglobin. 2004;28(4):347–351.
  • Liebhaber SA, Cash FE, Ballas SK. Human α-globin gene expression. The dominant role of the α 2-locus in mRNA and protein synthesis. J Biol Chem. 1986;261(32):15327–15333.
  • Yang X, Yan JM, Li J, et al. Hydrops fetalis associated with compound heterozygosity for Hb Zurich–Albisrieden (HBA2: C.178G>C) and the Southeast Asian (– –SEA/) deletion. Hemoglobin. 2016;40(5):353–355.
  • Du L, Bao X, He W, et al. Severe fetal anemia and hydrops fetalis associated with compound heterozygosity for Hb Zurich-Albisrieden (HBA2:c.178G>C) and Hb Quong Sze (HBA2:c.377T>C). J Int Med Res. 2021;49(7):3000605211031429.
  • Pedroso GA, Kimura EM, Santos MNN, et al. Thalassemia major phenotype caused by HB Zürich-Albisrieden [α2 59(E8) Gly>Arg (HBA2:C.178G>C)] in a Brazilian child. Pediatr Blood Cancer. 2018;65(12):e27413.
  • Fang J, Chen L, Zeng R, et al. The Hb H disease genotypes in Southern China. Hemoglobin. 2014;38(1):76–78.
  • Jiang H, Huang L-Y, Zhen L, et al. Two α1-globin gene point mutations causing severe Hb H disease. Hemoglobin. 2017;41(4-6):293–296.
  • Jiang F, Zuo L, Li J, et al. Evaluation of intervention strategy of thalassemia for couples of childbearing ages in Centre of Southern China. J Clin Lab Anal. 2021;35(10):e23990.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.