Transport of Insulin in Modified Valia-Chien Chambers and Caco-2 Cell Monolayers

REFERENCES

• Agarwal V., Nazzal S., Reddy I. K., Khan M. A. Transport studies of insulin across rat jejunum in the presence of chicken and duck ovomucoids. J. Pharm. Pharmcol. 2001; 53(8)1131–1138
   PubMed Web of Science ®Google Scholar
• Alachi A., Greenwood R. Human insulin absorption from the intestine in diabetic rats. Drug Dev. Ind. Pharm. 1994; 20(14)2333–2339
   Web of Science ®Google Scholar
• Asada H., Douen T., Waki M., Adachi S., Fujita T., Yamamato A., Muranishi S. Absorption characteristics of chemically modified-insulin derivatives with various fatty acids in the small and large intestine. J. Pharm. Sci. 1995; 84(6)682–687
   PubMed Web of Science ®Google Scholar
• Bai J. P. F., Chang L. L. Effects of enzyme inhibitors and insulin concentration on transepithelial transport of insulin in rats. J. Pharm. Pharmacol. 1996; 48(10)1078–1082
   PubMed Web of Science ®Google Scholar
• Banga A. K., Katakam M., Mitra R. Transdermal iontophoretic delivery and degradation of vasopressin across human cadaver skin. Int. J. Pharm. 1995; 116(2)211–216
   Google Scholar
• Bendayan M., Ziv E., Ben S. R., Bar O. H., Kidron M. Morpho-cytochemical and biochemical evidence for insulin absorption by the rat ileal epithelium. Diabetologia 1990; 33(4)197–204
   PubMed Web of Science ®Google Scholar
• Bendayan M., Ziv E., Gingra D., Ben S. R., Bar O. H., Kidron M. Biochemical and morpho-cytochemical evidence for the intestinal absorption of insulin in control and diabetic rats. Comparison between the effectiveness of duodenal and colon mucosa. Diabetologia 1994; 37(2)119–126
   PubMed Web of Science ®Google Scholar
• Bernkop-Schnurch A., Walker G. Multifunctional matrices for oral peptide delivery. Crit. Rev. Ther. Drug Carr. Syst. 2001; 18(5)459–501
   PubMed Web of Science ®Google Scholar
• Berggren S., Hoogstraate J., Fagerholm U., Lennernäs H. Characterization of jejunal absorption and apical efflux of ropivacaine, lidocaine and bupivacaine in the rat using in situ and in vitro absorption models. Eur. J. Pharm. Sci. 2004; 21(4)553–560
   PubMed Web of Science ®Google Scholar
• Boisset M., Botham R. P., Haegele K. D., Lenfant B., Pachot J. Absorption of angiotensin [#x025A1]antagonists in Ussing chambers, Caco-2, perfused jejunum loop and in vivo: Importance of drug ionization in the in vitro prediction of in vivo absorption. Eur. J. Pharm. Sci. 2000; 10(3)215–224
   PubMed Web of Science ®Google Scholar
• Bowen W. R., Calvo J. I., Hernández A. Steps of membrane blocking in flux decline during protein microfiltration. J. Membrane. Sci. 1995; 101(1–2)153–165
   Web of Science ®Google Scholar
• Brandsch M., Miyamoto Y., Ganapathy V., Leibach F. H. Expression and protein kinase C-dependent regulation of peptide/H+ co-transport system in the Caco-2 human colon carcinoma cell line. Biochem. J. 1994; 299: 253–260
   PubMed Web of Science ®Google Scholar
• Chen G. S., Kim D. D., Chien Y. W. Dual-controlled transdermal delivery of levonorgestrel and estradiol: enhanced permeation and modulated delivery. J. Contr. Rel. 1995; 34(2)129–143
   Web of Science ®Google Scholar
• Chien YW. Human insulin: Basic sciences to therapeutic uses. Drug Dev. Ind. Pharm. 1996; 22(8)753–789
   Web of Science ®Google Scholar
• Chun I. K., Chien Y. W. Transmucosal delivery of methionine enkephalin. 1. Solution stability and kinetics of degradation in various rabbit mucosa extracts. J. Pharm. Sci. 1993; 82(4)373–378
   PubMed Web of Science ®Google Scholar
• Clinchy B., Youssefi M. R., Håkansson L. Differences in adsorption of serum proteins and production of IL-1ra by human monocytes incubated in different tissue culture microtiter plates. J. Immunol. Methods 2003; 282(1–2)53–61
   PubMed Web of Science ®Google Scholar
• Daugherty A. L., Mrsny R. J. Regulation of the intestinal epithelial paracellular barrier. Pharm. Sci. Technol. Today 1999; 2(7)281–287
   PubMedGoogle Scholar
• Delie F., Rubas W. A. human colonic cell line sharing similarities with enterocytes as a model to examine oral absorption: advantages and limitations of the Caco-2 model. Crit. Rev. Ther. Drug Carrier Syst. 1997; 14(3)221–226
   PubMed Web of Science ®Google Scholar
• Ghilzai N. M. K. New developments in insulin delivery. Drug Dev. Ind. Pharm. 2003; 29(3)253–265
   PubMed Web of Science ®Google Scholar
• Greenwood R., Al-Achi A. Human insulin diffusion profile through a layer of Caco-2 cells. Drug Dev. Ind. Pharm. 1997; 23(2)221–224
   Web of Science ®Google Scholar
• Güell C., Davis R. H. Membrane fouling during microfiltration of protein mixtures. J. Membrane. Sci. 1996; 119(2)269–284
   Web of Science ®Google Scholar
• Hoogstraate A. J., Cullander C., Nagelkerke J. F., Senel S., Verhoef J. C., Junginger H. E., Boddé H. E. Diffusion rates and transport pathways of fluorescein isothiocyanate (FITC)-labeled model compounds through buccal epithelium. Pharm. Res. 1994; 11(1)83–89
   PubMed Web of Science ®Google Scholar
• Hunter J., Hirst B. H., Simmons N. L. P-glycoprotein-mediated secretory drug transport in human intestinal epithelial Caco-2 cell layers. Pharm. Res. 1993; 10(5)743–749
   PubMed Web of Science ®Google Scholar
• Hunter J., Jepson M. A., Tsuruo T., Simmons N. L. Functional expression of P-glycoprotein in apical membrane of human intestinal Caco-2 cells. J. Biol. Chem. 1993; 268(20)14991–14997
   PubMed Web of Science ®Google Scholar
• Kim D. D., Chien Y. W. Simultaneous skin permeation of dideoxynucleoside-type anti-HIV drugs. J. Contr. Rel. 1996; 40(1–2)67–76
   Web of Science ®Google Scholar
• Kontturi K., Vuoristo M. Adsorption of globular proteins on polymeric microfiltration membranes. Desalination 1996; 104(1–2)99–105
   Web of Science ®Google Scholar
• Krishna G., Chen K. J., Lin C. C., Nomeir A. A. Estimation of permeability in Caco-2 monolayer of compounds that exhibit extensive nonspecific binding. Pharm. Res. 1998; 1(Suppl)S8
   Google Scholar
• Lennernäs H., Nylander S., Ungell A. L. Jejunal permeability: a comparison between the Ussing chamber technique and the single-pass perfusion in humans. Pharm. Res. 1997; 14(5)667–671
   PubMed Web of Science ®Google Scholar
• McRoberts J. A., Aranda R., Riley N., Kang H. Insulin regulates the paracellular permeability of cultured intestinal epithelial-cell monolayers. J. Clin. Invest. 1990; 85(4)1127–1134
   PubMed Web of Science ®Google Scholar
• Meaney C. M., O'Driscoll C. M. A comparison of the permeation enhancement potential of simple bile salt and mixed bile salt : fatty acid micellar systems using the Caco-2 cell culture model. Int. J. Pharm. 2000; 207(1–2)7
   PubMedGoogle Scholar
• Morishita M., Morishita I., Takayama K., Machida Y., Nagai T. Site-dependent effect of aprotinin, sodium caprate, Na2EDTA and sodium glycocholate on intestinal absorption of insulin. Biol. Pharm. Bull. 1993; 16(1)68–72
   PubMed Web of Science ®Google Scholar
• Saha P., Kou J. H. Effect of bovine serum albumin on drug permeability estimation across Caco-2 monolayers. Eur. J. Pharm. Biopharm. 2002; 54(3)319–324
   PubMed Web of Science ®Google Scholar
• Sällberg M., Blixt M., Zhang Z. X., Ekstrand J. Passive adsorption of immunologically active and inactive synthetic peptides to polystyrene is influenced by the proportion of non-polar residues in the peptide. Immunol. Lett. 1995; 46(1–2)25–30
   PubMed Web of Science ®Google Scholar
• Sayani A. P., Kim D. D, Frenkl T. L., Chun I. K., Wang Y. J., Chien Y. W. Transmucosal delivery of enkephalins – comparative enhancing effects of dihydrofusidates and bile-salts. S.T.P. Pharm. Sci. 1994; 4(6)470–476
   Google Scholar
• Schilling R. J., Mitra A. K. Intestinal mucosal transport of insulin. Int. J. Pharm. 1990; 62(1)53–62
   Web of Science ®Google Scholar
• Sharma R. C., Inoue S., Roitelman J., Schimke R. T., Simoni R. D. Peptide transport by the multidrug resistance. J. Biol. Chem. 1992; 267(9)5731–5734
   PubMed Web of Science ®Google Scholar
• Sonne O. Receptor-mediated degradation and internalization of insulin in the adenocarcinoma cell line HT-29 from human colon. Mol. Endocrinol. 1985; 39: 39–48
   Web of Science ®Google Scholar
• Still J. G. Development of oral insulin. Diabetes/Metab. Res. Rev. 2002; 18(Suppl)S29–S37
   Google Scholar
• Trier J. S., Madara J. L. Physiology of the Gastrointestinal Tract. Raven Press, New York 1981; 925–962
   Google Scholar
• Uchiyama T., Sugiyama T., Quan Y. S., Kotani A., Okada N., Fujita T., Muranishi S., Yamamoto A. Enhanced permeability of insulin across the rat intestinal membrane by various absorption enhancers: their intestinal mucosal toxicity and absorption-enhancing mechanism of n-lauryl-β-D-maltopyranoside. J. Pharm. Pharmacol. 1999; 51(11)1241–1250
   PubMed Web of Science ®Google Scholar
• Ungell A. L. Absorption from the gastrointestinal tract. Current Status on Targeted Drug Delivery to the Gastrointestinal Tract. Greenwood, Capsugel Americas 1993; 79–84
   Google Scholar
• Wadell C., Björk E., Camber O. Permeability of porcine nasal mucosa correlated with human nasal absorption. Eur. J. Pharm. Sci. 2003; 18(1)47–53
   PubMed Web of Science ®Google Scholar
• Wu S. J., Robinson J. R. Transport of human growth hormone across Caco-2 cells with novel delivery agents: evidence for P-glycoprotein involvement. J. Contr. Rel. 1999; 62(1–2)171–177
   PubMed Web of Science ®Google Scholar
• Yamada K., Murakami M., Yamamoto A., Takada K., Muranishi S. Type hepatic uptake of liposomes in the rat. J. Pharm. Pharmacol. 1992; 44(9)711–721
   Google Scholar
• Yee S. In vitro permeability across Caco-2 cells (colonic) can predict in vivo (small intestinal) absorption in man: face or myth. Pharm. Res. 1997; 14(6)763–766
   PubMed Web of Science ®Google Scholar
• Zornoza T., Cano-Cebrián M. J., Nalda-Molina R., Guerri C., Granero L., Polache A. Assessment and modulation of acamprosate intestinal absorption: comparative studies using in situ, in vitro (CACO-2 cell monolayers) and in vivo models. Eur. J. Pharm. Sci. 2004; 22(5)347–356
   PubMed Web of Science ®Google Scholar