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Research Article

Preparation and In Vitro Characteristics of Lactoferrin-loaded Chitosan Microparticles

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Pages 641-647 | Published online: 26 Sep 2008

REFERENCES

  • Alsarra I. A., El-Bagory I., Bayomi M. A. Chitosan and sodium sulfate as excipients in the preparation of prolonged release theophylline tablets. Drug Dev. Ind. Pharm. 2005; 31: 385–395
  • Arnold R. R., Brewer M., Gauthier J. J. Bactericidal activity of human lactoferrin: sensitivity of a variety of microorganisms. Infect. Immun. 1980; 28: 893–898
  • Arnold R. R., Cole M. F., McGhee J. R. A bactericidal effect for human lactoferrin. Science 1977; 197: 263–265
  • Chen Y., Willmott N., Anderson J., Florence A. T. Comparison of albumin and casein microspheres as a carrier for doxorubicin. J. Pharm. Pharmacol. 1987; 39: 978–985
  • Cirioni O., Giacometti A., Barchiesi F., Scalise G. Inhibition of growth of Pneumocystis carinii by lactoferrins alone and in combination with pyrimethamine, clarithromycin and minocycline. J. Antimicrob. Chemother. 2000; 46: 577–582
  • Haversen L. A., Engberg I., Baltzer L., Dolphin G., Hanson L. A., Mattsby-Baltzer I. Human lactoferrin and peptides derived from a surface-exposed helical region reduce experimental Escherichia coli urinary tract infection in mice. Infect. Immun. 2000; 68: 5816–5823
  • Hejazi R., Amiji M. Stomach-specific anti-H. pylori therapy. I: Preparation and characterization of tetracyline-loaded chitosan microspheres. Int. J. Pharm. 2002; 235: 87–94
  • Hejazi R., Amiji M. Chitosan-based gastrointestinal delivery systems. J. Control Release 2003; 89: 151–165
  • Hori M., Onishi H., Machida Y. Evaluation of Eudragit-coated chitosan microparticles as an oral immune delivery system. Int. J. Pharm. 2005; 297: 223–234
  • Hu Y., Jiang X., Ding Y., Ge H., Yuan Y., Yang C. Synthesis and characterization of chitosan-poly(acrylic acid) nanoparticles. Biomaterials 2002; 23: 3193–3201
  • Iigo M., Kuhara T., Ushida Y., Sekine K., Moore M. A., Tsuda H. Inhibitory effects of bovine lactoferrin on colon carcinoma 26 lung metastasis in mice. Clin. Exp. Metastasis 1999; 17: 35–40
  • Ishikado A., Imanaka H., Takeuchi T., Harada E., Makino T. Liposomalization of lactoferrin enhanced it's anti-inflammatory effects via oral administration. Biol. Pharm. Bull. 2005; 28: 1717–1721
  • Jenssen H. Anti herpes simplex virus activity of lactoferrin/lactoferricin- an example of antiviral activity of antimicrobial protein/peptide. Cell. Mol. Life Sci. 2005; 62: 3002–3013
  • Kaur I. P., Smitha R. Penetration enhancers and ocular bioadhesives: two new avenues for ophthalmic drug delivery. Drug Dev. Ind. Pharm. 2002; 28: 353–369
  • Kuipers M. E., Heegsma J., Bakker H. I., Meijer D. K., Swart P. J., Frijlink E. W., Eissens A. C., de Vries-Hospers H. G., van den Berg J. J. Design and fungicidal activity of mucoadhesive lactoferrin tablets for the treatment of oropharyngeal candidosis. Drug Deliv. 2002; 9: 31–38
  • Lee N. Y., Kawai K., Nakamura I., Tanaka T., Kumura H., Shimazaki K. Susceptibilities against bovine lactoferrin with microorganisms isolated from mastitic milk. J. Vet. Med. Sci. 2004; 66: 1267–1269
  • Legrand D., Elass E., Pierce A., Mazurier J. Lactoferrin and host defence: an overview of its immuno-modulating and anti-inflammatory properties. Biometals 2004; 17: 225–229
  • Mi F. L., Tan Y. C., Liang H. F., Sung H. W. In vivo biocompatibility and degradability of a novel injectable-chitosan-based implant. Biomaterials 2002; 23: 181–191
  • Nafee N. A., Ismail F. A., Boraie N. A., Mortada L. M. Mucoadhesive delivery systems. II. Formulation and in-vitro/in-vivo evaluation of buccal mucoadhesive tablets containing water-soluble drugs. Drug Dev. Ind. Pharm. 2004; 30: 995–1004
  • Orsi N. The antimicrobial activity of lactoferrin: current status and perspectives. Biometals 2004; 17: 189–196
  • Samaranayake Y. H., Samaranayake L. P., Pow E. H., Beena V. T., Yeung K. W. Antifungal effects of lysozyme and lactoferrin against genetically similar, sequential Candida albicans isolates from a human immunodeficiency virus-infected southern Chinese cohort. J. Clin. Microbiol. 2001; 39: 3296–3302
  • Shimizu H. Development of an enteric-coated lactoferrin tablet and its application. Biometals 2004; 17: 343–347
  • Shimoda J., Onishi H., Machida Y. Bioadhesive characteristics of chitosan microspheres to the mucosa of rat small intestine. Drug Dev. Ind. Pharm. 2001; 27: 567–576
  • Suzuki Y. A., Lopez V., Lonnerdal B. Mammalian lactoferrin receptors: structure and function. Cell Mol. Life Sci. 2005; 62: 2560–2575
  • Tabata Y., Ikada Y. Effect of the size and surface charge of polymer microspheres on their phagocytosis by macrophage. Biomaterials 1988; 9: 356–362
  • Takakura N., Wakabayashi H., Ishibashi H., Teraguchi S., Tamura Y., Yamaguchi H., Abe S. Oral lactoferrin treatment of experimental oral candidiasis in mice. Antimicrob. Agents Chemother. 2003; 47: 2619–2623
  • Trif M., Guillen C., Vaughan D. M., Telfer J. M., Brewer J. M., Roseanu A., Brock J.H. Liposomes as possible carriers for lactoferrin in the local treatment of inflammatory diseases. Exp. Biol. Med. 2001; 226: 559–564
  • Wakabayashi H., Abe S., Teraguchi S., Hayasawa H., Yamaguchi H. Inhibition of hyphal growth of azole-resistant strains of Candida albicans by triazole antifungal agents in the presence of lactoferrin-related compounds. Antimicrob. Agents Chemother. 1998; 42: 1587–1591
  • Weinberg E. D. Iron and susceptibility to infectious disease. Science 1974; 184: 952–956
  • Yoshino T., Machida Y., Onishi H., Nagai T. Preparation and characterization of chitosan microspheres containing doxifluridine. Drug Dev. Ind. Pharm. 2003; 29: 417–427

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