In Vitro Assessment of Acyclovir Permeation Across Cell Monolayers in the Presence of Absorption Enhancers

REFERENCES

• Anderberg E. K., Artursson P. Epithelial transport of drugs in cell culture VIII. Effect of sodium dodecyl sulphate on cell membranes and tight junction permeability in human intestinal epithelial (Caco-2) cells. J. Pharm. Sci. 1993; 82: 392–398
   PubMed Web of Science ®Google Scholar
• Artursson P., Lindmark T., Davis S. S., Ilium L. Effect of chitosanon the permeability of monolayers of intestinal epithelial cells (Caco-2). Pharm. Res. 1994; 11: 1358–1361
   PubMed Web of Science ®Google Scholar
• Aungst B. J. Optimising oral bioavailability of pharmaceutical leads. AAPS Newsmagazine 2006; 9: 3
   Google Scholar
• Balda M. S., Whitney J. A., Flores C., Gonzalez S., Cereijido M., Matter K. Functional dissociation of paracellular permeability and transepithelial electrical resistance and disruption of the apical-basolateral intramembrane diffusion barrier by expression of a mutant tight junction membrane protein. J.Cell Biol. 1996; 134: 1031–1049
   PubMed Web of Science ®Google Scholar
• Bernkop-Schnurch A. Chitosan and its derivatives: Potential excipients for per oral peptide delivery systems. Int. J. Pharm. 2000; 194: 1–13
   PubMed Web of Science ®Google Scholar
• Canfield P. E., Geerdes A. M., Molitoris B. A. Effect of reversible ATP depletion on tight junction integrity in LLC-PK1 cells. Am. J. Physiol. 1991; 261: 1038–1045
   PubMed Web of Science ®Google Scholar
• De Clercq E. Antivirals for the treatment of herpesvirus infections. J. Antimicrob. Chemother. 1993; 32: 121–132
   PubMed Web of Science ®Google Scholar
• Dodane V., Khan M. A., Merwin J. R. Effect of chitosan on epithelial permeability and structure. Int. J. Pharm. 1999; 182: 21–32
   PubMed Web of Science ®Google Scholar
• Eckelman W. C. Radiolabeling with technetium-99m to study high-capacity and low capacity biochemical systems. Eur. J. Nucl. Med. 1995; 22: 249–263
   PubMedGoogle Scholar
• Elion G. B., Furman P. A., Fyfe J. A., de Miranda P., Beauchamp L., Schaeffer H. J. Selectivity of action of an antiherpetic agent, 9-(2-hydroxyethoxymethyl) guanine. Proc. Natl. Acad. Sci. U.S.A. 1977; 74: 5716–5720
   PubMed Web of Science ®Google Scholar
• Freshney R. I. Culture of animal cells: A manual of basic technique. Wiley, New York 1987
   Google Scholar
• Furuse M., Fujita K., Hiiragi T., Fujimoto K., Tsukita S. Claudin-1 and -2: Novel integral membrane proteins localizing at tight junctions with no sequence similarity to occluding. J. Cell Biol. 1998; 141: 1539–1550
   PubMed Web of Science ®Google Scholar
• Furuse M., Hirase T., Itoh M., Nagafuchi A., Yonemura S., Tsukita S., et al. Occludin: A novel integral membrane protein localizing at tight junctions. J. Cell Biol. 1993; 123: 1777–1788
   PubMed Web of Science ®Google Scholar
• Hidalgo I. J. Assessing the absorption of new pharmaceuticals. Curr. Top. Med. Chem. 2001; 1: 385–401
   PubMedGoogle Scholar
• Hovgaard L., Brondsted H. Drug delivery studies in Caco-2 monolayers. IV. Absorption enhancer effects of cyclodextrins. Pharm. Res. 1995; 12: 1328–1332
   PubMed Web of Science ®Google Scholar
• Irvine J. D., Takahashi L., Lockhart K., Cheong J., Tolan J. W., Selick H. E., et al. MDCK (Madin-Darby canine kidney) cells: A tool for membrane permeability screening. J. Pharm. Sci. 1999; 88: 28–33
   PubMed Web of Science ®Google Scholar
• Jain S. K., Jain R. K., Chourasia M. K., Jain A. K., Chalasani K. B., Soni V., et al. Design and development of multivesicular liposomal depot delivery system for controlled systemic delivery of acyclovir sodium. AAPS Pharm. Sci., Tech. 2005; 6: E35–E41
   PubMed Web of Science ®Google Scholar
• Junginger H. E., Verhoef J. C. Macromolecules as safe penetration enhancers for hydrophilic drugs—A fiction?. Pharm. Sci. Technol. Today 1998; 1: 370–376
   Google Scholar
• Kerec M., Bogataj M., Veranic P., Mrhar A. Permeability of pig urinary bladder wall: The effect of chitosan and the role of calcium. Eur. J. Pharm. Sci. 2005; 25: 113–121
   PubMed Web of Science ®Google Scholar
• Kotze A. F., Lueßen H. L., de Leeuw B. J., de Boer A. G., Verhoef J. C., Junginger H. E. Comparison of the effect of different chitosan salts and N-trimethyl chitosan chloride on the permeability of intestinal epithelial cells (Caco-2). J. Control. Release 1998; 51: 35–46
   PubMed Web of Science ®Google Scholar
• Kotze A. F., Thanou M. M., Lueβen H. L., de Leeuw B. J., de Boer A. G., Verhoef J. C., et al. Enhancement of paracellular drug transport with highly quaternized N-trimethyl chitosan chloride in neutral environment: In vitro evaluation in intestinal epithelial cells (Caco-2). J. Pharm. Sci. 1999; 88: 253–257
   PubMed Web of Science ®Google Scholar
• Kristl A., Tukker J. J. Negative correlation of n-octanol/water partition coefficient and transport of some guanine derivatives through rat jejunum in vitro. Pharm. Res. 1998; 15: 499–501
   PubMed Web of Science ®Google Scholar
• Lehr C. M., Bouwstra J. A., Schacht E. H., Junginger H. E. In vitro evaluation of mucoadhesive properties of chitosan and some other natural polymers. Int. J. Pharm. 1992; 78: 43–48
   Web of Science ®Google Scholar
• Masson M., Loftsson T., Masson G., Stefansson E. cyclodextrins as permeation enhancers: Some theoretical evaluations and in vitro testing. J. Control. Release 1999; 59: 107–118
   PubMed Web of Science ®Google Scholar
• Miranda P. D., Blum M. R. Pharmacokinetics of acyclovir after intravenous and oral administration. J. Antimicrob. Chemother. 1983; 12: 29–37
   PubMed Web of Science ®Google Scholar
• Mishra A. K., Panwar P., Hosono M., Chuttani K., Mishra P., Sharma R. K., et al. A new bifunctional chelating agent conjugated with monoclonal antibody and labelled with technetium-99m for targeted scintigraphy: 6-(4-isothiocyanatobenzyl)-5, 7-dioxo-1, 11-(carboxymethyl)-1, 4, 8, 11-tetraazacyclotridecane. J. Drug Target. 2004; 12: 559–567
   PubMed Web of Science ®Google Scholar
• Mukherjee T., Squillantea E., Gillespieb M., Shao J. Transepithelial electrical resistance is not a reliable measurement of the Caco-2 monolayer integrity in Transwell. Drug Deliv. 2004; 11: 11–18
   PubMed Web of Science ®Google Scholar
• Noach A. B. J., Sakai M., Blom-Roosemalen M. C., de Jonge H. R., de Boer A. G., Breimer D. D. Effect of anisotonic conditions on the transport of hydrophilic model compounds across monolayers of human colonic cell lines. J. Pharmacol. Exp. Ther. 1994; 270: 1373–1380
   PubMed Web of Science ®Google Scholar
• Ranaldi G., Marigliano I., Vespignani I., Perozzi G., Sambuy Y. The effect of chitosan and other polycations on tight junction permeability in the human intestinal Caco-2 cell line. J. Nutr. Biochem. 2002; 13: 157–167
   PubMed Web of Science ®Google Scholar
• Schaeffer H. J., Beauchamp L., de Miranda P., Elion G. B., Bauer D. J., Collins P. 9-(2-Hydroxyethoxymethyl) guanine activity against viruses of the herpes group. Nature 1978; 272: 583–585
   PubMed Web of Science ®Google Scholar
• Schipper N. G. M., Olsson S., Hoogstraate J. A., deBoer A. G., Varum K. M., Artursson P. Chitosans as absorption enhancers for poorly absorbable drugs 2: Mechanism of absorption enhancement. Pharm. Res. 1997; 14: 923–929
   PubMed Web of Science ®Google Scholar
• Shah P. J, Jogani V., Bagchi T., Misra A. Role of Caco-2 cell monolayers in prediction of intestinal drug absorption. Biotechnol. Prog. 2006; 22: 186–198
   PubMed Web of Science ®Google Scholar
• Smith J., Wood E., Dornish M. Effect of chitosan on epithelial cell tight junctions. Pharm. Res. 2004; 21: 43–49
   PubMed Web of Science ®Google Scholar
• Stagni G., Ali M. E., Weng D. Pharmacokinetics of acyclovir in rabbit skin after IV-bolus, ointment, and iontophoretic administrations. Int. J. Pharm. 2004; 274: 201–211
   PubMed Web of Science ®Google Scholar
• Taub M. E., Kristensen L., Frokjaer S. Optimized conditions for MDCK cell permeability and turbidimetric solubility studies using compounds representative of BCS classes I-IV. Eur. J. Pharm. Sci. 2002; 15: 331–340
   PubMed Web of Science ®Google Scholar
• Thanou M. M., Verhoef J. C., Junginger H. E. Oral absorption and enhancement by chitosan and its derivatives. Adv. Drug Del. Rev. 2001; 52: 117–126
   PubMed Web of Science ®Google Scholar
• Tirumalasetty P., Eley J. G. Evaluation of dodecylmaltoside as a permeability enhancer for insulin using human carcinoma cells. J. Pharm. Sci. 2005; 94: 246–255
   PubMed Web of Science ®Google Scholar
• Tirumalasetty P., Eley J. G. Permeability enhancing effects of the alkylglycoside, octylglucoside, on insulin permeation across epithelial membrane in vitro. J. Pharm. Pharmaceut. Sci. 2006; 9: 32–39
   PubMed Web of Science ®Google Scholar
• Tolle-Sander S., Lentz K. A., Maeda D. Y., Coop A., Polli J. E. Increased acyclovir oral bioavailability via a bile acid conjugate. Mol. Pharm. 2004; 1: 40–48
   PubMed Web of Science ®Google Scholar
• Udata C., Patel J., Pal D., Hejchman E., Cushman M., Mitra A. K. Enhanced transport of a novel anti-HIV agent/cosalane and its congeners across human intestinal epithelial (Caco-2) cell monolayers. Int. J. Pharm. 2003; 250: 157–168
   PubMed Web of Science ®Google Scholar
• Vrueh R. L. A., de Smith P. L., Lee C. P. Transport of L-valine-acyclovir via the oligopeptide transporter in the human intestinal cell line, Caco-2. J. Pharmacol. Expt., Ther. 1998; 286: 1166–1170
   PubMed Web of Science ®Google Scholar