Preparation and Body Distribution of Freeze-Dried Powder of Ursolic Acid Phospholipid Nanoparticles

References

• W. Abdelwahed, G. Degobert, H. Fessi. 2006a. Investigation of nanocapsules stabilization by amorphous excipients during freeze-drying and storage. Eur. J. Pharm. Biopharm. 63:87–94.
   PubMed Web of Science ®Google Scholar
• W. Abdelwahed, G. Degobert, H. Fessi. 2006b. A pilot study of freeze-drying of poly(epsilon–caprolactone) nanocapsules stabilized by poly(vinyl alcohol): Formulation and process optimization. Int. J. Pharm. 17:178–188.
   Google Scholar
• I. Brigger, C. Dubernet, P. Couvreur. 2002. Nanoparticles in cancer therapy and diagnosis. Adv. Drug Deliv. Rev. 54:631–651.
   PubMed Web of Science ®Google Scholar
• C. Cardenas, A. R. Quesada, M. A. Medina. 2004. Effects of ursolic acid on different steps of the angiogenic process. Biochem. Biophys. Res. Commun. 320:402–40.
   PubMed Web of Science ®Google Scholar
• M. Chacon, J. Molpeceres, L. Berges, M. Guzman, M. R. Aberturas. 1999. Stability and freeze-drying of cyclosporine loaded poly(D, L lactide–glycolide) carriers. Eur. J. Pharm. Sci. 8:99–107.
   PubMed Web of Science ®Google Scholar
• P. Couvreur, C. Dubernet, F. Puisieux. 1995. Controlled drug delivery with nanoparticles: Current possibilities and future trend. Eur. J. Pharm. Biopharm. 41:2–13.
   Web of Science ®Google Scholar
• M. P. Desai, V. Labhasetwar, G. L. Amidon, R. J. Levy. 1996. Gastrointestinal uptake of biodegradable microparticles: Effect of particle size. Pharm. Res. 13:1838–1845.
   PubMed Web of Science ®Google Scholar
• H. Fessi, J. P. Devissaguet, F. Puisieux. 1992. Process for the preparation of dispersible colloidal systems of a substance in the form of nanoparticles, US Patent No. 5, 118, 528.
   Google Scholar
• I. Fumiyoshi, N. Tomoko. 2005. Preparation and characterization of solid lipid nanoparticles loaded traditional Chinese medicine. Colloids Surf. B Biointerfaces 41:257–262.
   PubMedGoogle Scholar
• S. A. Goldblith, L. Rey, W. W. Rothmayr. 1975. Freeze drying and advanced food technology. London, UK: Academic press.
   Google Scholar
• P. K. Gupta, C. T. Hung. 1989. Quantitative evaluation of targeted drug delivery system. Int. J. Pharm. 56 (3):217–226.
   Web of Science ®Google Scholar
• Y. L. Hsu, P. L. Kuo, C. C. Lin. 2004. Proliferative inhibition, cell cycle dysregulation, and induction of apoptosis is by ursolic acid in human non-small cell lung cancer A549 cells. Life Sci. 75:2303–2316.
   PubMed Web of Science ®Google Scholar
• M. T. Huang, C. T. Ho, Z. Y. Wang, T. Ferraro, Y. R. Lou, K. Stauber, W. Ma, C. Georgiadis, J. D. Laskin, A. H. Conney. 1994. Inhibition of skin tumorigenesis by rosemary and its constituents camosol and ursolic acid. Cancer Res. 54:701–708.
   PubMed Web of Science ®Google Scholar
• A. Hutchings, A. H. Scott, G. Lewis, A. Cunningham. 1996. Zulu medicinal plants: An inventory. Scotsville: University of Natal Press.
   Google Scholar
• K. A. Kim, J. S. Lee, H. J. Park, J. W. Kim, C. J. Kim, I. S. Shim, N. J. Kim, S. Lim. 2004. Inhibition of cytochrome P450 activities by oleanolic acid and ursolic acid in human liver microsomes. Life Sci. 74:2769–2779.
   PubMed Web of Science ®Google Scholar
• Y. N. Konan, R. Gurny, E. Allémann. 2002. Preparation and characterization of sterile and freeze-dried sub-200 nm nanoparticles. Int. J. Pharm. 233:239–252.
   PubMed Web of Science ®Google Scholar
• H. Y. Lee, H. Y. Chung, K. H. Kim, J. J. Lee, K. W. Kim. 1994. Induction of differentiation in the cultured F9 teratocarcinoma stem cells by triterpene acids. J. Cancer Res. Clin. Oncol. 120 (9):513–518.
   PubMed Web of Science ®Google Scholar
• J. Liu. 1995. Pharmacology of oleanolic acid and ursolic acid. J. Ethnopharmacol. 49:4957–4968.
   Google Scholar
• S. Martin-Aragon, B. de las Heras, M. I. Sanchez-Reus, J. Benedi. 2001. Pharmacological modification of endogenous antioxidant enzymes by ursolic acid on tetrachloride-induced liver damage in rats and primary cultures of rat hepatocytes. Exp. Toxicol. Pathol. 53:199–206.
   PubMed Web of Science ®Google Scholar
• W. Mehnert, K. Mader. 2001. Solid lipid nanoparticles production, characterization and applications. Adv. Drug Deliv. Rev. 47:165–196.
   PubMed Web of Science ®Google Scholar
• S. M. Moghimi. 1995. Mechanisms regulating body distribution of nanospheres conditioned with pluronic and tetronic block co-polymers. Adv. Drug Deliv. Rev. 16:183–193.
   Web of Science ®Google Scholar
• M. Niikawa, H. Hayashi, T. Sato, H. Nagase, H. Kito. 1993. Isolation of substances from glossy privet (Ligustrum lucidum Ait.) inhibiting the mutagenicity of benzo[a]pyrene in bacteria. Mutat. Res. 319:1–9.
   PubMed Web of Science ®Google Scholar
• J. Panyam, V. Labhasetwar. 2003. Biodegradable nanoparticles for drug and gene delivery to cells and tissue. Adv. Drug Deliv. Rev. 55 (3):329–347.
   PubMed Web of Science ®Google Scholar
• M. C. Perez-Camino, A. Cert. 1999. Quantitative determination of hydroxy pentacyclic triterpene acids in vegetable oils. J. Agric. Food Chem. 47:1558–1572.
   PubMed Web of Science ®Google Scholar
• K. R. Price, I. T. Johnson, R. R. Fenwick. 1987. The chemistry and biological significance of saponins in foods and feeding staffs. CRC Crit. Rev. Food Sci. Nutr. 26:27–135.
   Google Scholar
• B. Saraswat, P. K. S. Visen, R. Dayal. 1996. Protective action of ursolic acid against chemical induce hepatotoxicity in rats. Indian J. Pharmacol. 28:232–239.
   Google Scholar
• M. A. Schubert, C. C. Muller-Goymann. 2003. Solvent injection as a new approach for manufacturing lipid nanoparticles––evaluation of the method and process parameters. Eur. J. Pharm. Biopharm. 55:125–131.
   PubMed Web of Science ®Google Scholar
• B. Siekmann, K. Westesen. 1996. Investigation on solid lipid nanoparticles prepared by precipitation in o/w emulsion. Eur. J. Pharm. Biopharm. 43:104–109.
   Google Scholar
• A. Simon, A. Najid, A. J. Chulia, C. Delage, M. Rigaud. 1992. Inhibition of lipoxygenase activity and HL60 leukemic cell proliferation by ursolic acid isolated from heather flowers (Calluna vulgaris). Biochim. Biophys. Acta 1125:68–72.
   PubMed Web of Science ®Google Scholar
• B. Sjöström, B. Bergenstahl. 1992. Preparation of submicron drug particles in lecithin-stabilized o/w emulsions I. Model studies of the precipitation of cholestreryl acetate. Int. J. Pharm. 88:53–62.
   Web of Science ®Google Scholar
• M. Trotta, M. Gallarate, F. Pattarino, S. Morel. 2001. Emulsions containing partially water-miscible solvents for the preparation of drug nanosuspensions. J. Control. Release 76:119–128.
   PubMed Web of Science ®Google Scholar
• C. H. Wang, D. J. Sun. 1998. Advance in the study of physical and chemical stability of liposomes. Chin. Pharm. J. 3365–3368.
   Google Scholar
• X. J. Xiong, W. Chen, K. Q. Li. 2001. Study on the experiment of the poison of ursolic acid. J. Yichun Medi. Coll. 13:54.
   Google Scholar
• S. C. Yang, L. F. Lu, Y. Cai, J. B. Zhu, B. W. Liang, C. Z. Yang. 1999. Body distribution in mice of intravenously injected camptothec in solid lipid nanoparticles. J. Control. Release 59:299–307.
   PubMed Web of Science ®Google Scholar
• H. J. You, C. Y. Choi, J. Y. Kim, S. J. Park, K. S. Hahm, H. G. Jeong. 2001. Ursolic acid enhances nitric oxide and tumor necrosis factor-α production via nuclear factor-kB activation in the resting macrophages. FEBS Lett. 509:156–160.
   PubMed Web of Science ®Google Scholar
• H. S. Young, H. Y. Chung, C. K. Lee, K. Y. Park, T. Yokosawa, H. Oura. 1994. Ursolic acid inhibits aflatoxin B1-induced mutagenisity in a salmonella assay system. Biol. Pharm. Bull. 17:990–992.
   PubMed Web of Science ®Google Scholar
• X. J. Zhou, Y. M. Yi. 2004. Preparation and quality evaluation of ursolic acid phospholipid nanoparticles. Herald Med. 23 (7):492–494.
   Google Scholar