Advanced search
Publication Cover
Drug Development and Industrial Pharmacy Volume 35, 2009 - Issue 10
Submit an article Journal homepage
179
Views
22
CrossRef citations to date
0
Altmetric
Original Article

Hollow spherical nanoparticulate aggregates as potential ultrasound contrast agent: shell thickness characterization

Kunn Hadinoto School of Chemical and Biomedical Engineering, Nanyang Technological University, SingaporeCorrespondence[email protected]
&
Wean Sin Cheow School of Chemical and Biomedical Engineering, Nanyang Technological University, Singapore
Pages 1167-1179 | Received 18 Nov 2008, Accepted 13 Feb 2009, Published online: 08 May 2009

References

  • Klibanov AL. (1999). Targeted delivery of gas-filled microspheres, contrast agents for ultrasound imaging. Adv Drug Deliv Rev, 37(1–3):139–57.
  • Lindner JR. (2004). Microbubbles in medical imaging: Current applications and future directions. Nat Rev Drug Discov, 3(6):527–32.
  • Klibanov AL. (2002). Ultrasound contrast agents: Development of the field and current status, Contrast Agents Ii. Top Curr Chem, 222:73–106.
  • Ferrara K, Pollard R, Borden M. (2007). Ultrasound microbubble contrast agents: Fundamentals and application to gene and drug delivery. Ann Rev Biomed Eng, 9:415–47.
  • Krasovitski B, Kimmel E. (2006). Stability of an encapsulated bubble shell. Ultrasonics, 44(2):216–20.
  • Landau LD, Lifshitz EM. (1976). Mechanics, 1. New York: Pergamon Press.
  • Raisinghani A, DeMaria AN. (2001). Physical principles of microbubble ultrasound contrast agents, Symposium on Contrast Echocardiography (CE), Newport, Rhode Island, , 3J–7J.
  • Bjerknes K, Sontum PC, Smistad G, Agerkvist I. (1997). Preparation of polymeric microbubbles: Formulation studies and product characterisation. Int J Pharm, 158(2):129–36.
  • El-Sherif DM, Wheatley MA. (2003). Development of a novel method for synthesis of a polymeric ultrasound contrast agent. J Biomed Mater Res Part A, 66A(2):347–55.
  • Narayan P, Wheatley MA. (1999). Preparation and characterization of hollow microcapsules for use as ultrasound contrast agents. Polymer Eng Sci, 39(11):2242–55.
  • Straub JA, Chickering DE, Church CC, Shah B, Hanlon T, Bernstein H. (2005). Porous PLGA microparticles: AI-700, an intravenously administered ultrasound contrast agent for use in echocardiography. J Control Release, 108(1):21–32.
  • Pisani E, (2006). Polymeric nano/microcapsules of liquid perfluorocarbons for ultrasonic imaging: Physical characterization. Langmuir, 22(9):4397–402.
  • Schmidt W, Roessling G. (2006). Novel manufacturing process of hollow polymer microspheres. Chem Eng Sci, 61(15):4973–81.
  • Hadinoto K, Zhu K, Tan RBH. (2007b). Drug release study of large hollow nanoparticulate aggregates carrier particles for pulmonary delivery. Int J Pharm, 341(1–2):195–206.
  • Rossi S, Waton G, Krafft MP. (2008). Small phospholipid-coated gas bubbles can last longer than larger ones. Chemphyschem, 9(14):1982–5.
  • Tsapis N, (2005). Onset of buckling in drying droplets of colloidal suspensions. Phys Rev Letters, 94(1):1–4. 018302
  • Govender T, Stolnik S, Garnett MC, Illum L, Davis SS. (1999). PLGA nanoparticles prepared by nanoprecipitation: Drug loading and release studies of a water soluble drug. J Control Release, 57(2):171–85.
  • Edwards DA, Dunbar C. (2002). Bioengineering of therapeutic aerosols. Ann Rev Biomed Eng, 4:93–107.
  • Park PIP, Jonnalagadda S. (2006). Predictors of glass transition in the biodegradable polylactide and poly-lactide-co-glycolide polymers. J Appl Polymer Sci, 100(3):1983–7.
  • Hadinoto K, Phanapavudhikul P, Kewu Z, Tan RBH. (2007a). Dry powder aerosol delivery of large hollow nanoparticulate aggregates as prospective carriers of nanoparticulate drugs: Effects of phospholipids. Int J Pharm, 333(1–2):187–98.
  • Chaubal MV, Popescu C. (2008). Conversion of nanosuspensions into dry powders by spray drying: A case study. Pharma Res, 25(10):2302–8.
  • Chiou H, Chan HK, Heng D, Prud'homme RK, Raper JA. (2008). A novel production method for inhalable cyclosporine A powders by confined liquid impinging jet precipitation. J Aero Sci, 39(6):500–9.
  • Freitas C, Muller RH. (1998). Spray-drying of solid lipid nanoparticles SLN (TM). Eur J Pharm Biopharm, 46(2):145–51.
  • Abdullah EC, Geldart D. (1999). The use of bulk density measurements as flowability indicators. Powder Technology, 102(2):151–65.
  • Iskandar F, Gradon L, Okuyama K. (2003). Control of the morphology of nanostructured particles prepared by the spray drying of a nanoparticle sol. J Coll Inter Sci, 265(2):296–303.
  • Bergna H, Roberts WO. (2006). Colloidal. Silica, FL: CRC Press Taylor & Francis.
  • Sugiyama Y, Larsen RJ, Kim JW, Weitz DA. (2006). Buckling and crumpling of drying droplets of colloid-polymer suspensions. Langmuir, 22(14):6024–30.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.