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Original Article

Spray-drying process optimization for manufacture of drug–cyclodextrin complex powder using design of experiments

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Pages 1219-1229 | Received 23 Aug 2008, Accepted 10 Mar 2009, Published online: 08 May 2009

References

  • Amidon GL, Lennernas H, Shah VP, Crison JR. (1995). A theoretical basis for a biopharmaceutic drug classification: The correlation of in vitro drug product dissolution and in vivo bioavailability. Pharm Res, 12:413–20.
  • Dressman JB, Amidon GL, Reppas C, Shah VP. (1998). Dissolution testing as a prognostic tool for oral drug absorption: Immediate release dosage forms. Pharm Res, 15:11–22.
  • Davis ME, Brewster M. (2004). Cyclodextrin-based pharmaceutics: Past, present and future. Nat Rev Drug Discov, 3:1023–35.
  • Brewster ME, Loftsson T. (2007). Cyclodextrins as pharmaceutical solubilizers. Adv Drug Deliv Rev, 59:645–66.
  • Lin SZ, Wouessidjewe D, Poelman MC, Duchene D. (1991). Indomethacin and cyclodextrin complexes. Int J Pharm, 69:211–9.
  • Ramprakash G, Nagarsenker MS. (2001). Cyclodextrin based oral delivery of flurbiprofen: Effect of method of preparation on drug release and studies on in-vivo performance. Proceedings of the 28th international symposium on controlled release of bioactive materials and 4th consumer & diversified products conference, vol. 28, Controlled Release Society, Inc., San Diego, CA, 772–3.
  • Miller LA, Carrier RL, Ahmed I. (2007). Practical considerations in development of solid dosage forms that contain cyclodextrin. J Pharm Sci, 96:1691–707.
  • Sinha VR, Anitha R, Ghosj S, Nanda A, Kumaria R. (2005). Complexation of celecoxib with beta-cyclodextrin: Characterization of the interaction in solution and in solid state. J Pharm Sci, 94:676–87.
  • Broadhead J, Edmond Rouan SK, Rhodes CT. (1992). The spray drying of pharmaceuticals. Drug Dev Ind Pharm, 18:1169–206.
  • Muller CR, Bassani VL, Pohlmann AR, Michalowski CB, Petrovick PR, Guterres SS. (2000). Preparation and characterization of spray-dried nanocapsules. Drug Dev Ind Pharm, 26:343–7.
  • Desai KGH, Park HJ. (2005). Encapsulation of vitamin C in tripolyphosphate cross-linked chitosan microspheres by spray drying. J Microencapsul, 22:179–92.
  • Oakley DE. (1997). Produce uniform particles by spray drying. Chem Eng Prog,, 93:48–54.
  • Masters K. (1991). Spray drying handbook. New York: Longman Scientific and Technical.
  • Conte U, Conti B, Giunchedi P, Maggi L. (1994). Spray dried polylactide microsphere preparation: Influence of the technological parameters. Drug Dev Ind Pharm, 20:253–8.
  • Wendel S, Celik M. (1997). An overview of spray drying applications. Pharm Technol, 10:124–56.
  • Tagne PT, Briancon S, Fessi H. (2006). Spray-dried microparticles containing polymeric nanacapsules: Formulation aspects, liquid phase interactions and particle characteristics. Int J Pharm, 325:63–74.
  • FDA guidance of industry. (2006). ICH Q8 Pharmaceutical development. U.S. Department of Health and Human Services, FDA/CDER/CBER. http://www.fda.gov/.
  • Billon A, Bataille B, Cassanas G, Jacob M. (2000). Development of spray dried acetaminophen microparticles using experimental designs. Int J Pharm, 203:159–68.
  • Vaithiyalingam S, Khan MA. (2002). Optimization and characterization of controlled release multi-particulate beads formulated with a customized cellulose acetate butyrate dispersion. Int J Pharm, 234:179–93.
  • Devay A, Mayer K, Pal S, Antal I. (2006). Investigation on drug dissolution and particle characteristics of pellets related to manufacturing process variables of high-shear granulation. J Biochem Biophys Methods, 69:197–205.
  • Box GEP, Hunter WG, Hunter JS. (1976). Statistics for experimenters, an introduction to design, data analysis, and model building. New York: Wiley.
  • Lieberman HA, Rieger MM, Banker GS. (1988). Pharmaceutical dosage form—Disperse systems. New York: Marcel Dekker, 438–64.
  • Giunchedi P, Juliano C, Gavini E, Cossu M, Sorrenti M. (2002). Formulation and in vivo evaluation of chlorhexidine buccal tablets prepared using drug-loaded chitosan microspheres. Eur J Pharm BioPharm, 53:233–9.
  • Prinn KB, Costantini RH, Tracy M. (2002). Statistical modeling of protein spray drying at the lab scale. AAPS PharmSciTech, 3:1–8.
  • Martinac A, Filipovic-Grcic J, Perissuti B, Voinivich D, Pavilic Z. (2005). Spray-dried chitosan/ethylcellulose microspheres for nasal drug delivery: Swelling study and evaluation of in vitro drug release properties. J Microencap, 22:549–61.
  • Gonnissen Y, Remon JP, Vervaet C. (2008). Effect of maltodextrin and superdisintegrant in directly compressible powder mixtures prepared via co-spray drying. Eur J Pharm BioPharm, 68:277–82.

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