185
Views
2
CrossRef citations to date
0
Altmetric
Research Articles

Increased dissolution rates of tranilast solid dispersions extruded with inorganic excipients

, , , , &
Pages 947-957 | Received 04 Aug 2016, Accepted 13 Jan 2017, Published online: 20 Feb 2017

References

  • Llusa M, Mohr S, Baumgartner R, et al. Continuous low-dose feeding of highly active pharmaceutical ingredients in hot-melt extrusion. Drug Dev Ind Pharm 2016;42:1360–4.
  • Tiwari RV, Patil H, Repka MA. Contribution of hot-melt extrusion technology to advance drug delivery in the 21st century. Expert Opin Drug Deliv 2016;13:451–64.
  • Maniruzzaman M, Douroumis D. Continuous manufacturing and process analytical tools. Int J Pharm 2015;496:1–2.
  • Abu-Diak OA, Jones DS, Andrews GP. Understanding the performance of melt-extruded poly(ethylene oxide)-bicalutamide solid dispersions: characterisation of microstructural properties using thermal, spectroscopic and drug release methods. J Pharm Sci 2012;101:200–13.
  • Park JB, Prodduturi S, Morott J, et al. Development of an antifungal denture adhesive film for oral candidiasis utilizing hot melt extrusion technology. Expert Opin Drug Deliv 2015;12:1–13.
  • Andrews GP, Jones DS. Hot melt extrusion – processing solid solutions? J Pharm Pharmacol 2014;66:145–7.
  • Li L, AbuBaker O, Shao ZJ. Characterization of poly(ethylene oxide) as a drug carrier in hot-melt extrusion. Drug Dev Ind Pharm 2006;32:991–1002.
  • Jones DS, Margetson DN, McAllister MS, et al. Thermodynamically stable amorphous drug dispersions in amorphous hydrophilic polymers engineered by hot melt extrusion. Chem Eng Res 2014;92:3046–54.
  • Liu H, Zhang X, Suwardie H, et al. Miscibility studies of indomethacin and Eudragit® E PO by thermal, rheological, and spectroscopic analysis. J Pharm Sci 2012;101:2204–12.
  • Qi S, Belton P, Nollenberger K, et al. Characterization and prediction of phase separation in hot-melt extruded solid dispersions: a thermal, microscopic and NMR relaxometry study. Pharm Res 2010;27:1869–83.
  • Crowley MM, Zhang F, Repka MA, et al. Pharmaceutical applications of hot-melt extrusion: part I. Drug Dev Ind Pharm 2007;33:909–26.
  • Tackenberg MW, Krauss R, Marmann A, et al. Encapsulation of liquids using a counter rotating twin screw extruder. Eur J Pharm Biopharm 2015;89:9–17.
  • Kalivoda A, Fischbach M, Kleinebudde P. Application of mixtures of polymeric carriers for dissolution enhancement of fenofibrate using hot-melt extrusion. Int J Pharm 2012;429:58–68.
  • Maniruzzaman M, Rana MM, Boateng JS, et al. Drug Dev Ind Pharm 2013;39:218–27.
  • Gryczke A, Schminke GS, Maniruzzaman M, et al. Development and evaluation of orally disintegrating tablets (ODTs) containing ibuprofen granules prepared by hot melt extrusion. Colloids Surf B: Biointerfaces 2011;86:275–84.
  • Lang B, McGinity JW, Williams IIIRO. Hot-melt extrusion – basic principles and pharmaceutical applications. Drug Dev Ind Pharm 2014;40:1133–55.
  • Gupta MK, Tseng Y-C, Goldman D, Bogner RH. Hydrogen bonding with adsorbent during storage governs drug dissolution from solid-dispersion granules. Pharm Res 2002;19:1663–72.
  • Kinoshita M, Baba K, Nagayasu A, et al. Improvement of solubility and oral bioavailability of a poorly water-soluble drug, TAS-301, by its melt-adsorption on a porous calcium silicate. J Pharm Sci 2002;91:362–70.
  • Bahl D, Bogner RH. Amorphization alone does not account for the enhancement of solubility of drug co-ground with silicate: the case of indomethacin. AAPS PharmSciTech 2008;9:146–53.
  • Maclean J, Medina C, Daurio D, et al. Manufacture and performance evaluation of a stable amorphous complex of an acidic drug molecule and neusilin. J Pharm Sci 2011;100:3332–44.
  • Maniruzzaman M, Nair A, Renault M, et al. Continuous twin-screw granulation for enhancing the dissolution of poorly water soluble drug. Int J Pharm 2015;496:52–62.
  • Maniruzzaman M, Nair A, Scoutaris N, et al. One-step continuous extrusion process for the manufacturing of solid dispersions. Int J Pharm 2015;496:42–51.
  • Neuslin® Technical Brochure; Fuji Chemical Industry Co., Ltd., Japan. Available from: www.neusilin.com [last accessed 10 Mar 2014].
  • Kawabata Y, Yamamoto K, Debari K, et al. Novel crystalline solid dispersion of tranilast with high photostability and improved oral bioavailability. Eur J Pharm Sci 2010;39:256–62.
  • The Society of Japanese Pharmacopoeia: Tranilast. Japanese Orange Book No. 12 Approved drug products with therapeutic equivalence evaluations. Tokyo: Yakuji Nippo Ltd.; 2002:171.
  • Suzuki H, Kojo Y, Yakushiji K, et al. Strategic application of self-micellizing solid dispersion technology to respirable powder formulation of tranilast for improved therapeutic potential. Int J Pharm 2016;499:255–62.
  • Sato H, Fujimori M, Suzuki H, et al. Absorption improvement of tranilast by forming highly soluble nano-size composite structures associated with α-glucosyl rutin via spray drying. Eur J Pharm Biopharm 2015;92:49–55.
  • Onoue S, Yamamoto K, Kawabata Y, Yamada S. In vitro/in vivo characterization of nanocrystalline formulation of tranilast with improved dissolution and hepatoprotective properties. Eur J Pharm Biopharm 2013;85:952–7.
  • Onoue S, Kojo Y, Aoki Y, et al. Physicochemical and pharmacokinetic characterization of amorphous solid dispersion of tranilast with enhanced solubility in gastric fluid and improved oral bioavailability. Drug Metab Pharmacokinet 2012;27:379–87.
  • US Pharmacopoeia, 2015. Available from: http://www.pharmacopeia.cn/v29240/usp29nf24s0_m40420.html [last accessed Sep 2015].
  • Fatouros DG, Douroumis D, Nikolakis V, et al. In vitro and in silico investigations of drug delivery via zeolite BEA. J Mater Chem 2011;21:7789.
  • Saerens L, Dierickx L, Quinten T, et al. In-line NIR spectroscopy for the understanding of polymer-drug interaction during pharmaceutical hot-melt extrusion. Eur J Pharm Biopharm 2012;81:230–7.
  • Coates PD, Barnes SE, Sibley MG, et al. In-process vibrational spectroscopy and ultrasound measurements in polymer melt extrusion. Polymer 2003;44:5937–49.
  • Islam MT, Scoutaris N, Maniruzzaman M, et al. Implementation of transmission NIR as a PAT tool for monitoring drug transformation during HME processing. Eur J Pharm Biopharm 2015;96:106–16.
  • Desiraju GR. C–H ··· O and other weak hydrogen bonds. From crystal engineering to virtual screening. Chem Commun 2005;24:2995–3001.
  • Six K, Leuner C, Dressman J, et al. Thermal properties of hot-stage extrudates of itraconazole and Eudragit E100: phase separation and polymorphism. J Therm Anal Cal 2002;68:591–601.
  • Six K, Daems T, de Hoon J, et al. Clinical study of solid dispersions of itraconazole prepared by hot-stage extrusion. Eur J Pharm Sci 2005;24:179–86.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.