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Research Article

Co-delivery of hydrophilic and hydrophobic drugs by micelles: a new approach using drug conjugated PEG–PCLNanoparticles

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Pages 1908-1918 | Received 15 Apr 2017, Accepted 09 Jul 2017, Published online: 03 Aug 2017

References

  • Lv L, Qiu K, Yu X, et al. Amphiphilic copolymeric micelles for doxorubicin and curcumin co-delivery to reverse multidrug resistance in breast cancer. J Biomed Nanotechnol. 2016;12:973–985.
  • Kheiri Manjili H, Sharafi A, Attari E, et al. Pharmacokinetics and in vitro and in vivo delivery of sulforaphane by PCL–PEG–PCL copolymeric-based micelles. Artif Cells Nanomed Biotechnol. 2017[Feb 1];[1–12]. [Epub ahead of print]. doi: 10.1080/21691401.2017.1282501
  • Yang Q, Yu X, Li T, et al. Hemoglobin-loaded triblock PCLA-PEG-PCLA copolymer vesicles: a potential oxygen carrier. J nanosci nanotechnol. 2016;16:6734–6740.
  • Laskar P, Saha B, Ghosh SK, et al. PEG based random copolymer micelles as drug carriers: the effect of hydrophobe content on drug solubilization and cytotoxicity. RSC Adv. 2015;5:16265–16276.
  • Xiao W, Chen X, Yang L, et al. Co-delivery of doxorubicin and plasmid by a novel FGFR-mediated cationic liposome. Int J Pharm. 2010;393:119–126.
  • Laskar P, Samanta S, Ghosh SK, et al. In vitro evaluation of pH-sensitive cholesterol-containing stable polymeric micelles for delivery of camptothecin. J Colloid Interface Sci. 2014;430:305–314.
  • Laskar P, Dey J, Ghosh SK. Evaluation of zwitterionic polymersomes spontaneously formed by pH-sensitive and biocompatible PEG based random copolymers as drug delivery systems. Colloids Surf B Biointerfaces. 2016;139:107–116.
  • Liu D, Yang F, Xiong F, et al. The smart drug delivery system and its clinical potential. Theranostics. 2016;6:1306–1323.
  • Fan L, Li F, Zhang H, et al. Co-delivery of PDTC and doxorubicin by multifunctional micellar nanoparticles to achieve active targeted drug delivery and overcome multidrug resistance. Biomaterials. 2010;31:5634.
  • Laskar P, Dey J, Banik P, et al. In vitro drug and gene delivery using random cationic copolymers forming stable and pH-sensitive polymersomes. Macromol Biosci. 2017. [Epub ahead of print]. doi: 10.1002/mabi.201600324
  • Laskar P, Dey J, Ghosh SK. Spontaneously formed redox- and pH-sensitive polymersomes by mPEG based cytocompatible random copolymers. J Colloid Interface Sci. 2017;501:22–33.
  • Danafar H, Rostamizadeh K, Davaran S, et al. Drug-conjugated PLA–PEG–PLA copolymers: a novel approach for controlled delivery of hydrophilic drugs by micelle formation. Pharm Dev Technol. 2015. [Epub ahead of print]. doi: 10.3109/10837450.2015.1125920
  • Zhang J, Wu D, Feng J. One-step way to form prodrug micelles with high amount drug loading. J Nanosci Nanotechnol. 2016;16:5586–5591.
  • Wang YLi, Zhao H, Peng JRong, et al. Targeting therapy of neuropilin-1 receptors overexpressed breast cancer by paclitaxel-loaded CK3-conjugated polymeric micelles. J Biomed Nanotechnol. 2016;12:2097–2111.
  • Lage H. ABC-transporters: implications on drug resistance from microorganisms to human cancers. Int J Antimicrob Agents. 2003;22:188–199.
  • Elkhodiry MA, Momah CC, Suwaidi SR, et al. Synergistic nanomedicine: passive, active and ultrasound-triggered drug delivery in cancer treatment. J Nanosci Nanotechnol. 2016;16:1–18.
  • Tang HD, Murphy CJ, Shen YQ, et al. Amphiphilic curcumin conjugate-forming nanoparticles as anticancerprodrug and drug carriers: in vitro and in vivo effects. Nanomedicine. 2010;5:855–865.
  • Manjili HK, Ghasemi P, Malvandi H, et al. Pharmacokinetics and in vivo delivery of curcumin by copolymeric mPEG-PCL micelles. Eur J Pharm Biopharm. 2017;116:17–30.
  • Danafar H, Rostamizadeh K, Hamidi M. Polylactide/Poly(ethylene glycol)/Polylactide triblock copolymer micelles as carrier for delivery of hydrophilic and hydrophobic drugs: a comparison study. Int J Pharm Investig. 2017. [Epub ahead of print]. doi: 10.1007/s40005-017-0334-8
  • Notarbartolo M, Poma P, Perri D, et al. Antitumor effects of curcumin, alone or in combination with cisplatin or doxorubicin, on human hepatic cancer cells. Analysis of their possible relationship to changes in NF-B activation levels and in IAP gene expression. Cancer Lett. 2005;1:53–65.
  • Zhu Y, Liao L. Applications of nanoparticles for anticancer drug delivery: a review. J Nanosci Nanotechnol. 2015;15:4753–4773.
  • Yang Y, QingFa G, JinRong P, Jing S, XiaoLing L, YongXiang Z, ZhiYong Q. Doxorubicin-conjugated heparin-coated superparamagnetic iron oxide nanoparticles for combined anticancer drug delivery and magnetic resonance imaging. J Biomed Nanotechnol. 2016;12:1963–1974.
  • Tonnesen HH, Masson M, Loftsson T. Studies of curcumin and curcuminoids. XXVII. Cyclodextrin complexation: solubility, chemical and photochemical stability. Int J Pharm. 2002;244:127–135.
  • Danafar H. Study of the composition of polycaprolactone/poly (Ethylene Glycol)/polycaprolactone copolymer and drug-to-polymer ratio on drug loading efficiency of curcumin to nanoparticles. J Nat Pharm Prod. 2016. [Epub ahead of print]. doi: 10.17795/jjnpp-34179
  • Liwei T, Buyun M, Qian Z, et al. Toxicity evaluation and anti-tumor study of docetaxel loaded mPEG-polyester micelles for breast cancer therapy. J Biomed Nanotechnol. 2017;13:393–408.
  • Cheng T, Liu J, Ren J, et al. Green tea catechin-based complex micelles combined with doxorubicin to overcome cardiotoxicity and multidrug resistance. Theranostics. 2016;6:1277–1292.
  • Ganta S, Amiji M. Coadministration of paclitaxel and curcumin in nanoemulsion formulations to overcome multidrug resistance in tumor cells. Mol Pharm. 2009;6:928–939.
  • Danafar H, Sharafi A, Kheiri Manjili H, et al. Sulforaphane delivery using mPEG–PCL co-polymer nanoparticles to breast cancer cells. Pharm Dev Technol. 2017;22:642–651.
  • Gharebaghi F, Dalali N, Ahmadi E, et al. Preparation of wormlike polymeric nanoparticles coated with silica for delivery of methotrexate and evaluation of anticancer activity against MCF7 cells. J Biomater Appl. 2017;31:1305–1316.

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