References
- Prausnitz MR, Mitragotri S, Langer R. Current status and future potential of transdermal drug delivery. Nat Rev Drug Discov. 2004;3:115–124.
- Wokovich AM, Prodduturi S, Doub WH, et al. Transdermal drug delivery system (TDDS) adhesion as a critical safety, efficacy and quality attribute. Eur J Pharm Biopharm. 2006;64:1–8.
- Ravula R, Herwadkar AK, Abla MJ, et al. Formulation optimization of a drug in adhesive transdermal analgesic patch. Drug Dev Ind Pharm. 2016;42:862–870.
- Kumar R, Philip A. Modified transdermal technologies: breaking the barriers of drug permeation via the skin. Trop J Pharm Res. 2007;6:633–677.
- Mithun B, Tamizharasi S, Sivakumar T. Anatomy of transdermal therapeutic systems: a detailed and updated perspective. Int J Pharm Sci. 2013;3:277–282.
- Sandhu P, Bilandi A, Kataria S, et al. Transdermal drug delivery system (patches), applications in present scenario. Int J Res Pharm Chem. 2011;1:1139–1151.
- Abdel Messih HA, Ishak RAH, Geneidi AS, et al. Nanoethosomes for transdermal delivery of tropisetron HCl: multi-factorial predictive modeling, characterization, and ex vivo skin permeation. Drug Dev Ind Pharm. 2017;43:958–971.
- Subedi RK, Oh SY, Chun MK, et al. Recent advances in transdermal drug delivery. Arch Pharm Res. 2010;33:339–351.
- Ma M, Di HJ, Zhang H, et al. Development of phospholipid vesicle-based permeation assay models capable of evaluating percutaneous penetration enhancing effect. Drug Dev Ind Pharm. 2017;43:2055–2063.
- Bhattacharya A, Ghosal SK. Effect of hydrophobic permeation enhancers on the release and skin permeation kinetics from matrix type transdermal drug delivery system of ketotifen fumarate. Acta Pol Pharm. 2001;58:101–105.
- Inoue K, Ogawa K, Okada J, Sugibayashi K. Enhancement of skin permeation of ketotifen by supersaturation generated by amorphous form of the drug. J Control Release. 2005;108:306–318.
- Mercaptopurine. In: Swedman SC, editor. Martindale: the complete drug reference. 34th ed. London (UK): Pharmaceutical Press; 2005.
- Hemangi JP, Jitendra SP, Keyur DP. Transdermal patch for ketotifen fumarate (ktf) as asthmatic drug. Int J Pharm Tech Res. 2009;1:1297–1304.
- Yousuf M, Ahmad M, Usman M, et al. Ketotifen fumarate and salbutamol sulphate combined transdermal patch formulations: in-vitro release and ex-vivo permeation studies. Indian J Pharm Sci. 2013;75:569–577.
- Wiwat P, Jirapornchai S, Prapaporn B, et al. Nicotine transdermal patches using polymeric natural rubber as the matrix controlling system: effect of polymer and plasticizer blends. J Membr Sci. 2012;411:81–90.
- Lee YL, Chiang CH, Chen JL. In vitro and in vivo percutaneous absorption studies of Ketotifene patches. Drug Dev Ind Pharm. 1994;20:2965–2976.
- Chiang CH, Chen JL, Liu YT, et al. Therapeutic effect and pharmacokinetics of ketotifen transdermal delivery system. Drug Dev Ind Pharm. 1998;24:213–217.
- Patel HJ, Patel JS, Patel KD. Transdermal patch for ketotifen fumarate (KTF) as asthmatic drug. Int J Pharm Tech Res. 2009;1:1297–1304.
- Lee EY, Chun MK, Chang JS, et al. Development of matrix based transdermal delivery system for ketotifen. J Pharm Investig. 2014;44:291–296.
- Chilcott RP, Price S. Principles and practice of skin toxicology. Chichester, UK: John Wiley & Sons, Ltd; 2008.
- Pandey A, Mittal A, Chauhan N, et al. Role of surfactants as penetration enhancer in transdermal drug delivery system. J Mol Pharm Org Process Res. 2014;2:113–121.
- Alexander A, Dwivedi S, Ajazuddin Giri TK, et al. Approaches for breaking the barriers of drug permeation through transdermal drug delivery. J Control Release. 2012;164:26–40.
- Hecht H, Srebnik S. Structural characterization of sodium alginate and calcium alginate. Biomacromolecules. 2016;17:2160–2167.
- Bektaş A, Cevher E, Güngör S, et al. Design and evaluation of polysaccharide-based transdermal films for the controlled delivery of nifedipine. Chem Pharm Bull. 2014;62:144–152.
- Falcone R, Jaffe M, Ravindra NM. New screening methodology for selection of polymeric matrices for transdermal drug delivery devices. Bioinspir Biomim Nan. 2013;2:65–75.
- Gasmi SN, Rihouey C, Picton L, et al. Hydrolysis of pullulan by entrapped pullulanase in Ca/alginate beads. Biopolymers. 2014;101:938–944.
- Pawar SN, Edgar KJ. Alginate derivatization: a review of chemistry, properties and applications. Biomaterials. 2012;33:3279–3305.
- Dettmar PW, Gil-Gonzalez D, Fisher J, et al. A comparative study on the raft chemical properties of various alginate antacid raft-forming products. Drug Dev Ind Pharm. Forthcoming. [cited 2017 Sep 13]. doi: 10.1080/03639045.2017.1371737
- Zhou Y, Liu S, Ming J, et al. Sustained release effects of berberine-loaded chitosan microspheres on in vitro chondrocyte culture. Drug Dev Ind Pharm. 2017;43:1703–1714.
- Jiang J, Liu Y, Wu C, et al. Development of drug-loaded chitosan hollow nanoparticles for delivery of paclitaxel to human lung cancer A549 cells. Drug Dev Ind Pharm. 2017;43:1304–1313.
- Crini G, Badot PM. Application of chitosan, a natural aminopolysaccharide, for dye removal from aqueous solutions by adsorption processes using batch studies: a review of recent literature. Prog Polym Sci. 2008;33:399–447.
- Younes I, Rinaudo M. Chitin and chitosan preparation from marine sources. Structure, properties and applications. Mar Drugs. 2015;13:1133–1174.
- Yu H, Nguyen MH, Hadinoto K. Effects of chitosan molecular weight on the physical and dissolution characteristics of amorphous curcumin–chitosan nanoparticle complex. Drug Dev Ind Pharm. Forthcoming. [cited 2017 Sep 11]. doi: 10.1080/03639045.2017.1373802
- Davoudi Z, Rabiee M, Houshmand B, et al. Development of chitosan/gelatin/keratin composite containing hydrocortisone sodium succinate as a buccal mucoadhesive patch to treat desquamative gingivitis. Drug Dev Ind Pharm. Forthcoming. [cited 2017 Sep 13]. doi: 10.1080/03639045.2017.1371738
- Cerchiara T, Luppi B, Bigucci F, et al. Physically cross-linked chitosan hydrogels as topical vehicles for hydrophilic drugs. J Pharm Pharmacol. 2002;54:1453–1462.
- Yusof NL, Wee A, Lim LY, et al. Flexible chitin films as potential wound dressing materials: wound model studies. J Biomed Mater Res. 2003;66:224–232.
- Satheeshababu BK, Shruthinag R. Synthesis and characterization of chitosan conjugate; design and evaluation of membrane moderated type transdermal drug delivery system. Indian J Pharm Sci. 2015;77:405–412.
- Aktar B, Erdal MS, Sagirli O, et al. Optimization of biopolymer based transdermal films of metoclopramide as an alternative delivery approach. Polymers. 2014;6:1350–1365.
- Meng X, Tian F, Yang J, et al. Chitosan and alginate polyelectrolyte complex membranes and their properties for wound dressing application. J Mater Sci: Mater Med. 2010;21:1751–1759.
- Lefnaoui S, Moulai-Mostefa N. Polyelectrolyte complex based on carboxymethyl-kappa-carrageenan and Eudragit RL 30D as prospective carriers for sustained drug delivery. Chem Eng Res Design. 2015;97:165–174.
- Rangasamy N, Natham NR. Cefixime trihydrate loaded chitosan-alginate transdermal patches. World J Pharm Sci. 2014;2:997–1008.
- Kassem A, Ismail FA, Naggar VF, et al. Preparation and evaluation of periodontal films based on polyelectrolyte complex formation. Pharm Dev Technol. 2015;20:297–305.
- Saleem MA, Azharuddin SKMD, Sadat A, et al. Studies on different chitosan polyelectrolyte complex hydrogels for modified release of diltiazem hydrochloride. Int J Pharm Pharm Sci. 2010;2:64–67.
- Gendelberg NR, Falcone F, Ravindra NM. Transdermal drug delivery through skin patches. J Sci Ind Metrol. 2016;1:11.
- Costa RR, Costa AMS, Caridade SG, et al. Compact saloplastic membranes of natural polysaccharides for soft tissue engineering. Chem Mater. 2015;27:7490–7502.
- Afreen S, Vishnu V, Al Saleh SS, et al. Design and in-vitro evaluation of controlled release tri-layer venlafaxine hydrochloride transdermal patch. Asian J Pharm Clin Res. 2015;8:271–277.
- Garala KC, Shinde AJ, Shah PH. Formulation and in-vitro characterization of monolithic matrix transdermal systems using HPMC/Eudragit S100 polymer blends. Int J Pharm Pharm Sci. 2009;1:108–120.
- Patel KN, Patel HR, Patel VA. Formulation and characterization of drug in adhesive transdermal patches of Diclofenac acid. Int J Pharm Pharm Sci. 2012;4:296–299.
- Shivaraj A, Panner Selvam R, Tamiz Mani T, et al. Design and evaluation of transdermal drug delivery of Ketotifen Fumarate. Int J Pharm Bio Res. 2010;1:42–47.
- Kumar A, Pullakandam N, Prabu S, et al. Transdermal drug delivery system: an overview. Int J Pharm Sci Rev Res. 2010;3:49–54.
- Gupta A, Garg S, Khar RK. Measurement of bioadhesion strength of mucoadhesive buccal tablet: design of an in vitro assembly. Ind Drugs. 1992;30:152–157.
- Patel VM, Prajapati BG, Patel MM. Design and characterization of chitosan-containing mucoadhesive buccal patches of propranolol hydrochloride. Acta Pharm. 2007;57:61–72.
- United States Pharmacopoeia USP 39–NF 34. The United States Pharmacopeial convention, Toronto, Canada; 2016.
- Korsmeyer RW, Gurny R, Docler E, et al. Mechanism of solute release from porous hydrophilic polymers. Int J Pharm. 1983;15:25–35.
- Costa P, Lobo JMS. Modeling and comparison of dissolution profiles. Eur J Pharm Sci. 2001;13:123–133.
- Shah S, Rabbani M. Study of percutaneous absorption of diclofenac diethylamine in the presence of cetrimide through hairless rabbit skin. J Res Sci. 2006;17:45–51.
- Klaus F. Analytical profiles of drug substances. Vol. 13. USA: Harcourt Brace Jovanovich, Publishers, Academic Press, Inc.; 1984.
- Gutschke E, Bracht S, Nagel S, et al. Adhesion testing of transdermal matrix patches with a probe tack test-in vitro and in vivo evaluation. Eur J Pharm Biopharm. 2010;75:399–404.
- Abdul Rasool BK, Aziz US, Sarheed O, et al. Design and evaluation of a bioadhesive film for transdermal delivery of propranolol hydrochloride. Acta Pharm. 2011;61:271–282.
- Pendekal MS, Tegginamat PK. Formulation and evaluation of a bioadhesive patch for buccal delivery of tizanidine. Acta Pharm Sinica. 2012;B2:318–324.
- Bagan J, Paderni C, Termine N, et al. Mucoadhesive polymers for oral transmucosal drug delivery: a review. Curr Pharm Des. 2012;18:5497–5514.
- Khutoryanskiy VV. Advances in mucoadhesion and mucoadhesive polymers. Macromol Biosci. 2011;11:748–764.
- Sedef CA, Sedef EM, Güngör S, et al. Optimization and characterization of chitosan films for transdermal delivery of ondansetron. Molecules. 2013;18:5455–5471.
- Kulig D, Zimoch-Korzycka A, Jarmoluk A, et al. Study on alginate-chitosan complex formed with different polymer ratios. Polymers. 2016;8:167–184.
- Park CR, Munday DL. Evaluation of selected polysaccharide excipients in buccoadhesive tablets for sustained release of nicotine. Drug Dev Ind Pharm. 2004;30:609–617.
- Lim LY, Wan LS. The effect of plasticizers on the properties of polyvinyl alcohol patches. Drug Dev Ind Pharm. 1994;20:1007–1020.
- Chauhan R, Mehta N, Jain A, et al. Optimization of plasticizer for diclofenac sodium transdermal film, permeation enhancement. Asian J Pharm Clin Res. 2011;4:178–180.
- Sanap GS, Dama GY, Karpe AS, et al. Preparation of transdermal monolithic systems of indapamide by solvent casting method and the use of vegetable oils as permeation enhancer. Int J Green Pharm. 2008;2:129–133.
- Azeem A, Ahmad FJ, Khar RK, et al. Nanocarrier for the transdermal delivery of an antiparkinsonian drug. AAPS PharmSciTech. 2009;10:1093–1103.
- Kumar P, Kumar S, Mishra DN, et al. Enhancement of ketorolac tromethamine permeability through rat skin using penetration enhancers: an ex-vivo study. Int J Pharm Investig. 2015;5:142–146.
- Alsarra IA, Bosela AA, Ahmed SM, et al. Proniosomes as a drug carrier for transdermal delivery of ketorolac. Eur J Pharm Biopharm. 2005;59:485–490.