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RESEARCH ARTICLE

Determination of precipitation inhibitory potential of polymers from amorphous solid dispersions

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Pages 1933-1941 | Received 07 May 2018, Accepted 17 Jul 2018, Published online: 11 Sep 2018

References

  • Butler JM, Dressman JB. The developability classification system: application of biopharmaceutics concepts to formulation development. J Pharm Sci. 2010;99(12):4940–4954.
  • Thiry J, Kok MG, Collard L, et al. Bioavailability enhancement of itraconazole-based solid dispersions produced by hot melt extrusion in the framework of the Three Rs rule. Eur J Pharm Sci. 2017;99:1–8.
  • Raina SA, Eerdenbrugh BV, Alonzo DE, et al. Trends in the precipitation and crystallization behavior of supersaturated aqueous solutions of poorly water‐soluble drugs assessed using synchrotron radiation. J Pharm Sci. 2015;104(6):1981–1992.
  • Raina SA, Zhang GG, Alonzo DE, et al. Enhancements and limits in drug membrane transport using supersaturated solutions of poorly water soluble drugs. J Pharm Sci. 2014;103(9):2736–2748.
  • Alonzo DE, Zhang GG, Zhou D, et al. Understanding the behavior of amorphous pharmaceutical systems during dissolution. Pharm Res. 2010;27(4):608–618.
  • Mistry P, Amponsah-Efah KK, Suryanarayanan R. Rapid assessment of the physical stability of amorphous solid dispersions. Cryst Growth Des. 2017;17(5):2478–2485.
  • Alonzo DE, Raina S, Zhou D, et al. Characterizing the impact of hydroxypropylmethyl cellulose on the growth and nucleation kinetics of felodipine from supersaturated solutions. Cryst Growth Des. 2012;12(3):1538–1547.
  • Chauhan H, Hui Gu C, Atef E. Correlating the behavior of polymers in solution as precipitation inhibitor to its amorphous stabilization ability in solid dispersions. J Pharm Sci. 2013;102(6):1924–1935.
  • Chauhan H, Kuldipkumar A, Barder T, et al. Correlation of inhibitory effects of polymers on indomethacin precipitation in solution and amorphous solid crystallization based on molecular interaction. Pharm Res. 2014;31(2):500–515.
  • Ilevbare GA, Liu H, Edgar KJ, et al. Inhibition of solution crystal growth of ritonavir by cellulose polymers–factors influencing polymer effectiveness. CrystEngComm. 2012;14(20):6503–6514.
  • Ilevbare GA, Liu H, Edgar KJ, et al. Maintaining supersaturation in aqueous drug solutions: impact of different polymers on induction times. Cryst Growth Des. 2012;13(2):740–751.
  • Ilevbare GA, Liu H, Edgar KJ, et al. Understanding polymer properties important for crystal growth inhibition- impact of chemically diverse polymers on solution crystal growth of ritonavir. Cryst Growth Des. 2012;12(6):3133–3143.
  • Prasad D, Chauhan H, Atef E. Role of molecular interactions for synergistic precipitation inhibition of poorly soluble drug in supersaturated drug–polymer–polymer ternary solution. Mol Pharm. 2016;13(3):756–765.
  • Chavan RB, Thipparaboina R, Kumar D, et al. Evaluation of the inhibitory potential of HPMC, PVP and HPC polymers on nucleation and crystal growth. RSC Adv. 2016;6(81):77569–77576.
  • Gupta P, Chawla G, Bansal AK. Physical stability and solubility advantage from amorphous celecoxib: the role of thermodynamic quantities and molecular mobility. Mol Pharm. 2004;1(6):406–413.
  • Choi J-S, Park J-S. Design of PVP/VA S-630 based tadalafil solid dispersion to enhance the dissolution rate. Eur J Pharm Sci. 2017;97:269–276.
  • Zhang Y, Huo M, Zhou J, et al. DDSolver: an add-in program for modeling and comparison of drug dissolution profiles. AAPS J. 2010;12(3):263–271.
  • Kumar D, Thipparaboina R, Modi SR, et al. Effect of HPMC concentration on crystal habit of nifedipine. Cryst Eng Comm. 2015;17(7):1615–1624.
  • Grooff D, De Villiers M, Liebenberg W. Thermal methods for evaluating polymorphic transitions in nifedipine. Thermochim Acta. 2007;454(1):33–42.
  • Kini A, Patel SB. Phase behavior, intermolecular interaction, and solid state characterization of amorphous solid dispersion of Febuxostat. Pharm Dev Technol. 2017;22(1):45–57.
  • Ziaee A, Albadarin AB, Padrela L, et al. Spray drying ternary amorphous solid dispersions of ibuprofen–an investigation into critical formulation and processing parameters. Euro J Pharm Biopharm. 2017;120:43–51.
  • Baird JA, Taylor LS. Evaluation of amorphous solid dispersion properties using thermal analysis techniques. Adv Drug Del Rev. 2012;64(5):396–421.
  • Cilurzo F, Minghetti P, Casiraghi A, et al. Characterization of nifedipine solid dispersions. Int J Pharm. 2002;242(1-2):313–317.
  • Triggle A, Shefter E, Triggle D. Crystal structures of calcium channel antagonists: 2, 6-dimethyl-3, 5-dicarbomethoxy-4-[2-nitro-, 3-cyano-, 4-(dimethylamino)-, and 2, 3, 4, 5, 6-pentafluorophenyl]-1, 4-dihydropyridine. J Med Chem. 1980;23(12):1442–1445.
  • Meng F, Trivino A, Prasad D, et al. Investigation and correlation of drug polymer miscibility and molecular interactions by various approaches for the preparation of amorphous solid dispersions. Eur J Pharm Sci. 2015;71, 12–24.
  • Higashi K, Hayashi H, Yamamoto K, et al. The effect of drug and EUDRAGIT® S 100 miscibility in solid dispersions on the drug and polymer dissolution rate. Int J Pharm. 2015;494(1):9–16.
  • Semjonov K, Kogermann K, Laidmäe I, et al. The formation and physical stability of two-phase solid dispersion systems of indomethacin in supercooled molten mixtures with different matrix formers. Eur J Pharm Sci. 2017;97:237–246.

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