References
- Cao R, Peng W, Wang Z, et al. β-Carboline alkaloids: biochemical and pharmacological functions. Curr Med Chem. 2007;14(4):479–500.
- Li SP, Cheng XM, Wang CH. A review on traditional uses, phytochemistry, pharmacology, pharmacokinetics and toxicology of the genus. Peganum J Ethnopharmacol. 2017;203:127–162.
- Hou JJ, Sun BC. STAT3: the key player in the network of inflammation and cancer. Prog Biochem Biophys. 2014;41:69–78.
- Wu JS, Hong HS. Relationship between hypertension and inflammation. Chin J Clin Pharmacol Ther. 2006;11:136–140.
- Wang C, Qin SB. Research progress of inflammation and vascular endothelial injury. Adv Cardiovasc Dis. 2015;36:89–92.
- Ji DB, Cui JR. Relationship between the initiation, development and therapy of tumor and inflammation. Chin J New Drugs. 2010;19:1551–1555.
- Feng LJ, Shen YX, Li J. Endoplasmic-reticulum stress and inflammatory response. Chinese Pharmacol Bull. 2013;29:760–766.
- Yamazaki Y, Kawano Y. Inhibitory effects of herbal alkaloids on the tumor necrosis factor-α and nitric oxide production in lipopolysaccharide-stimulated RAW264 macrophages. Chem Pharm Bull. 2011;59:388–391.
- Liu X, Li MX, Tan S, et al. Harmine is an inflammatory inhibitor through the suppression of NF-κB signaling. Biochem Bioph Res Co. 2017;489(3):332–338.
- Zeng CL, Ma GZ, Teng L, et al. Effects of alkaloids from Peganum harmala on mice models of psoriasis. Chin Tradit Pat Med. 2013;35:219–225.
- Adaay MH. Embryotoxicity of harmaline and harmalol hydrochloride on pregnant rats. J Mater Environ Sci. 2014;5:127–132.
- Louis ED, Jiang W, Gerbin M, et al. Relationship between blood harmane and harmine concentrations in familial essential tremor, sporadic essential tremor and controls. Neurotoxicology. 2010;31(6):674–679.
- Ting WW, Vest CD, Sontheimer RD. Sontheimer RD. review of traditional and novel modalitied that enhance the permeability of local therapeutics across the stratum corneum. Int J Dermatol. 2004;43(7):538–547.
- Ding ZR, Teng L, Dai XY, et al. Optimization of prescription and anti-pruritic effect of harmine hydrochloride cream. Chin Tradit Pat Med. 2010;32:753–757.
- Xing JG, Sun DJ, Guan H, et al. Prescription selecting of harmine HCl ointment. Chin Tradit Pat Med. 2011; 23:316–318.
- Ren LJ, Li Y, Sun T, et al. Screening of penetration enhancers for compound Luotuo Pengzi hydrogel pathches. China Pharm. 2016; 19:1834–1836.
- Godin B, Touitou E. Ethosomes: new prospects in transdermal delivery. Crit Rev Ther Drug Carrier Syst. 2003;20(1):63–102.
- Shi XQ, Zhao JH, Wang ZD, et al. Application of ethosomes as carriers in dermal and transdermal drug delivery. Chin J Exp Trad Med Form. 2013;19:352–355.
- Touitou E, Dayan N, Bergelson L, et al. Ethosomes-novel vesicular carriers for enhanced delivery: characterization and skin penetration properties. J Control Release. 2000;65(3):403–418.
- Zhang YT, Shen LN, Wu ZH, et al. Comparison of ethosomes and liposomes for skin delivery of psoralen for psoriasis therapy. Int J Pharm. 2014;471(1–2):449–452.
- Elsayed MM, Abdallah OY, Naggar VF, et al. Lipid vesicles for skin delivery of drugs: reviewing three decades of research. Int J Pharm. 2007;332(1–2):1–16.
- Marto J, Vitor C, Guerreiro A, et al. Ethosomes for enhanced skin delivery of griseofulvin. Colloid Surf B. 2016;146:616–623.
- Shen LN, Zhang YT, Wang Q, et al. Enhanced in vitro and in vivo skin deposition of apigenin delivered using ethosomes. Int J Pharm. 2014;460(1–2):280–288.
- Ma TY, Jiang JZ, Zhang LH, et al. Preparation and formulation optimization of harmine loaded ethosomes. Chin J Exp Tradit Med Formul. 2018;24(8):34–39.
- Yang YD, Cheng XM, Wang CH, et al. Study on the quality specification of seeds of Peganum harmala. Chin Pharm J. 2014;49(2):106–112.
- Khurana S, Jain NK, Bedi P. Nanoemulsion based gel for transdermal delivery of meloxicam: physio-chemical, mechanistic investigation. Life Sci. 2013;92(6–7):383–392.
- Guo T, Zhang YT, Zhao JH, et al. Nanostructured lipid carriers for percutaneous administration of alkaloids isolated from Aconitum sinomontanum. J Nanobiotechnol. 2015;46:1511–1514.
- Yan Y, Zhang HF, Sun JY, et al. Enhanced transdermal delivery of sinomenine hydrochloride by ethosomes for anti-inflammatory treatment. J Drug Deliv Sci Tec. 2016;3:201–207.
- Zhang L, Liang L, Gong C, et al. Simultaneous determination of harmine, harmaline and their metabolites harmol and harmalol in beagle dog plasma by UPLC–ESI-MS/MS and its application to a pharmacokinetic study. J Pharmceut Biomed. 2013;85:162–168.
- Zetler G, Back G, Iven H. Pharmacokinetics in the rat of the hallucinogenic alkaloids harmine and harmaline. Naunyn-Schmiedeberg's Arch Pharmacol. 1974;285(3):273–292.
- Fernández‐Dueñas V, Sánchez S, Planas E, et al. Adjuvant effect of caffeine on acetylsalicylic acid anti‐nociception: prostaglandin E2 synthesis determination in carrageenan‐induced peripheral inflammation in rat. Eur J Pain. 2008;12:157–163.
- Xu XT, Mou XQ, Xi QM, et al. Anti-inflammatory activity effect of 2-substituted-1,4,5,6 -tetrahydrocyclopenta [b] pyrrole on TPA-induced skin inflammation in mice. Bioorg Med Chem Lett. 2016;26(21):5334–5339.
- Ahad A, Raish M, Al-Mohizea AM, et al. Enhanced anti-inflammatory activity of carbopol loaded meloxicam nanoethosomes gel. Int J Bio Macromol. 2014;67:99–104.