259
Views
7
CrossRef citations to date
0
Altmetric
Research Articles

Pharmacokinetics and brain distribution studies of perphenazine-loaded solid lipid nanoparticles

, , , , &
Pages 146-152 | Received 05 Jul 2020, Accepted 18 Nov 2020, Published online: 18 Dec 2020

References

  • Radaic A , Martins-de-Souza D. The state of the art of nanopsychiatry for schizophrenia diagnostics and treatment. Nanomed Nanotechnol Biol Med. 2020; 28:102222.
  • Tandon R , Gaebel W , Barch DM , et al. Definition and description of schizophrenia in the DSM-5. Schizophr Res. 2013;150:3–10.
  • Laursen TM , Nordentoft M , Mortensen PB. Excess early mortality in schizophrenia. Annu Rev Clin Psychol. 2014;10:425–448.
  • Bloom DE , Cafiero E , Jané-Llopis E , et al. The global economic burden of noncommunicable diseases. Program on the Global Demography of Aging. 2012.
  • Lin C-H , Chen C-H , Lin Z-C , et al. Recent advances in oral delivery of drugs and bioactive natural products using solid lipid nanoparticles as the carriers. J Food Drug Anal. 2017;25:219–234.
  • Baboota S , Mustafa AG , Sahni JK , et al. Mechanistic approach for the development of ultrafine oil-water emulsions using monoglyceride and blends of medium and long chain triglycerides: enhancement of the solubility and bioavailability of perphenazine. J Excip Food Chem. 2016;4:1099.
  • Hartung B , Sampson S , Leucht S. Perphenazine for schizophrenia. Cochrane Database Syst Rev. 2015:CD003443.
  • Sun Y , Kang C , Liu F , et al. Delivery of antipsychotics with nanoparticles. Drug Dev Res. 2016;77:393–399.
  • Turunen E , Mannila J , Laitinen R , et al. Fast-dissolving sublingual solid dispersion and cyclodextrin complex increase the absorption of perphenazine in rabbits. J Pharm Pharmacol. 2011;63:19–25.
  • Dimitrijevic I , Pantic I. Application of nanoparticles in psychophysiology and psychiatry research. Rev Adv Mater Sci. 2014;83–88.
  • Salunkhe SS , Bhatia NM , Kawade VS , et al. Development of lipid based nanoparticulate drug delivery systems and drug carrier complexes for delivery to brain. J App Pharm Sci. 2015;5:110–129.
  • Meise U , Kurz M , Fleischhacker WW. Antipsychotic maintenance treatment of schizophrenia patients: is there a consensus? Schizophr Bull. 1994;20:215–225.
  • Müller RH , Mäder K , Gohla S. Solid lipid nanoparticles (SLN) for controlled drug delivery – a review of the state of the art. Eur J Pharm Biopharm. 2000;50:161–177.
  • Luo YFan , Chen DWei , Ren L , et al. Solid lipid nanoparticles for enhancing vinpocetine’s oral bioavailability. J Control Release. 2006;114:53–59.
  • Mehnert W , Mäder K. Solid lipid nanoparticles: production, characterization and applications. Adv Drug Delivery Rev. 2012;64:83–101.
  • Lavelle E , Sharif S , Thomas N , et al. The importance of gastrointestinal uptake of particles in the design of oral delivery systems. Adv Drug Delivery Rev. 1995;18:5–22.
  • Yang S , Zhu J , Lu Y , et al. Body distribution of camptothecin solid lipid nanoparticles after oral administration. Pharm Res. 1999;16:751–757.
  • Martins SM , Sarmento B , Nunes C , et al. Brain targeting effect of camptothecin-loaded solid lipid nanoparticles in rat after intravenous administration. Eur J Pharm Biopharm. 2013;85:488–502.
  • Patel M , Souto EB , Singh KK. Advances in brain drug targeting and delivery: limitations and challenges of solid lipid nanoparticles. Expert Opin Drug Deliv. 2013;10:889–905.
  • Kaur IP , Bhandari R , Bhandari S , et al. Potential of solid lipid nanoparticles in brain targeting. J Controlled Release. 2008;127:97–109.
  • Fond G , Macgregor A , Miot S. Nanopsychiatry-the potential role of nanotechnologies in the future of psychiatry: a systematic review. Eur Neuropsychopharmacol. 2013;23:1067–1071.
  • Natarajan J , Baskaran M , Humtsoe LC , et al. Enhanced brain targeting efficacy of Olanzapine through solid lipid nanoparticles. Artif Cells Nanomed Biotechnol. 2017;45:364–371.
  • Nikandish N , Hosseinzadeh L , Azandaryani AH , et al. The role of nanoparticle in brain permeability: an in-vitro BBB model. Iran J Pharm Res. 2016;15:403–413.
  • Joseph E , Saha RN. Investigations on pharmacokinetics and biodistribution of polymeric and solid lipid nanoparticulate systems of atypical antipsychotic drug: effect of material used and surface modification. Drug Dev Ind Pharm. 2017;43:678–686.
  • Kurd M , Sadegh Malvajerd S , Rezaee S , et al. Oral delivery of indinavir using mPEG-PCL nanoparticles: preparation, optimization, cellular uptake, transport and pharmacokinetic evaluation. Artif Cells Nanomed Biotechnol. 2019;47:2123–2133.
  • Müller RH , Rühl D , Runge S , et al. Cytotoxicity of solid lipid nanoparticles as a function of the lipid matrix and the surfactant. Pharm Res. 1997;14:458–462.
  • Pandita D , Ahuja A , Lather V , et al. Development of lipid-based nanoparticles for enhancing the oral bioavailability of paclitaxel. Aaps Pharmscitech. 2011;12:712–722.
  • Nooli M , Chella N , Kulhari H , et al. Solid lipid nanoparticles as vesicles for oral delivery of olmesartan medoxomil: formulation, optimization and in vivo evaluation. Drug Dev Ind Pharm. 2017;43:611–617.
  • Hansen LB , Larsen N-E. Plasma concentrations of perphenazine and its sulphoxide metabolite during continuous oral treatment. Psychopharmacology (Berl). 1977;53:127–130.
  • Naseri N , Valizadeh H , Zakeri-Milani P. Solid lipid nanoparticles and nanostructured lipid carriers: structure, preparation and application. Adv Pharm Bull. 2015;5:305–313.
  • Bhalekar MR , Madgulkar AR , Desale PS , et al. Formulation of piperine solid lipid nanoparticles (SLN) for treatment of rheumatoid arthritis. Drug Dev Ind Pharm. 2017;43:1003–1010.
  • Nasiri F , Faghfouri L , Hamidi M. Preparation, optimization and in-vitro characterization of α-tocopherol-loaded solid lipid nanoparticles (SLNs). Drug Dev Ind Pharm. 2020;46:142–159.
  • Yasir M , Sara UVS. Solid lipid nanoparticles for nose to brain delivery of haloperidol: in vitro drug release and pharmacokinetics evaluation. Acta Pharm Sin B. 2014;4:454–463.
  • Laitinen R , Suihko E , Bjorkqvist M , et al. Perphenazine solid dispersions for orally fast-disintegrating tablets: physical stability and formulation. Drug Dev Ind Pharm. 2010;36:601–613.
  • Dudhipala N , Janga KY. Lipid nanoparticles of zaleplon for improved oral delivery by Box-Behnken design: optimization, in vitro and in vivo evaluation. Drug Dev Ind Pharm. 2017;43:1205–1214.
  • Zhang Y , Huo M , Zhou J , et al. PKSolver: An add-in program for pharmacokinetic and pharmacodynamic data analysis in Microsoft Excel. Comput Methods Programs Biomed. 2010;99:306–314.
  • Freitas C , Müller RH. Effect of light and temperature on zeta potential and physical stability in solid lipid nanoparticle (SLN™) dispersions. Int J Pharm. 1998;168:221–229.
  • Jepson MA , Clark M , Foster N , et al. Targeting to intestinal M cells. J Anat. 1996;189:507.
  • Dwivedi P , Khatik R , Khandelwal K , et al. Pharmacokinetics study of arteether loaded solid lipid nanoparticles: an improved oral bioavailability in rats. Int J Pharm. 2014;466:321–327.
  • Manjunath K , Venkateswarlu V. Pharmacokinetics, tissue distribution and bioavailability of nitrendipine solid lipid nanoparticles after intravenous and intraduodenal administration. J Drug Target. 2006;14:632–645.
  • Chen L-T , Weiss L. The role of the sinus wall in the passage of erythrocytes through the spleen. Blood. 1973;41:529–537.
  • Harde H , Das M , Jain S. Solid lipid nanoparticles: an oral bioavailability enhancer vehicle. Expert Opin Drug Deliv. 2011;8:1407–1424.
  • Jose S , Anju S , Cinu T , et al. In vivo pharmacokinetics and biodistribution of resveratrol-loaded solid lipid nanoparticles for brain delivery. Int J Pharm. 2014;474:6–13.
  • de Mendoza AE-H , Préat V , Mollinedo F , et al. In vitro and in vivo efficacy of edelfosine-loaded lipid nanoparticles against glioma. J Controlled Release. 2011;156:421–426.
  • Kakkar V , Mishra AK , Chuttani K , et al. Proof of concept studies to confirm the delivery of curcumin loaded solid lipid nanoparticles (C-SLNs) to brain. Int J Pharm. 2013;448:354–359.
  • Girotra P , Singh SK. Multivariate optimization of rizatriptan benzoate-loaded solid lipid nanoparticles for brain targeting and migraine management. AAPS PharmSciTech. 2017;18:517–528.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.