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Research Articles

Study on the taste-masking effect and mechanism of Acesulfame K on berberine hydrochloride

ORCID Icon, , , , , , , , , , , & show all
Pages 92-102 | Received 28 Nov 2022, Accepted 13 Feb 2023, Published online: 01 Mar 2023

References

  • Zhong CP, Qian Y, Shu C, et al. Research progress in antimicrobial effects of berberine and its derivatives. Food Sci. 2013;34(7):321–325.
  • Guo YY, Feng Q, Yang YX, et al. Effects of berberine on the injury of gastric mucosal epithelial cells in mice infected with Helicobacter pylori. World Chinese Med. 2021;16(18):2703–2705.
  • Hu XL, Li YB, Zhang EJ, et al. Preparation and evaluation of orally disintegrating tablets containing taste-masked microcapsules of berberine hydrochloride. AAPS PharmSciTech. 2013;14(1):29–37.
  • Jiang H, Zhang D, He J, et al. A novel method to mask the bitter taste of berberine hydrochloride: powder surface modification. Pharmacogn Mag. 2018;14(54):253–260.
  • Kaushik D, Dureja H. Recent patents and patented technology platforms for pharmaceutical taste masking. Recent Pat Drug Deliv Formul. 2014;8(1):37–45.
  • Zheng X, Wu F, Hong Y, et al. Developments in taste-masking techniques for traditional Chinese medicines. Pharmaceutics. 2018;10(3):157.
  • Harmik,  Sohi,  Yasmin,  et al. Taste masking technologies in oral pharmaceuticals: recent developments and approaches. Drug Dev Ind Pharmacy. 2004;30(5):429–448.
  • Yu Y, Fan LY, Gao JD, et al. Preparation of berberine hydrochloride microcapsules and its in vitro release behavior. China Pharmacy. 2015;26(01):109–112.
  • Liu RX, Wang YL, Tian LY, et al. Masking efficiency and regularity of bitterness suppressants to berberine hydrochloride based on tongue taste and electronic tongue taste. Chinese Pharm J. 2019;54(3):208–218.
  • He J. Research on masking the bitterness of berberine hydrochloride and sanhuang tablets by the powder modification technology [Master]. Chengdu:Chengdu University of TCM; 2016.
  • Ley JP. Masking bitter taste by molecules. Chemosens Percept. 2008;1(1):58–77.
  • Li XL, Kang H, Tian LY, et al. Evaluation of different types of bitterness masking on inhibition of bitterness efficiency and law of four Chinese materia medicine decoctions of Gentianae radix et rhizoma, Sophorae flavescentis radix, Andrographis herba, and Nelumbinis plumula. Chinese Traditional and Herbal Drugs. 2018;49(22):5280–5291.
  • Lin C-H, Li H-Y, Wang S-H, et al. Consumption of non-nutritive sweetener, acesulfame potassium exacerbates atherosclerosis through dysregulation of lipid metabolism in ApoE−/− mice. Nutrients. 2021;13(11):3984.
  • Qurrat-Ul-Ain,  Khan SA. Artificial sweeteners: safe or unsafe? J Pak Med Assoc. 2015;65(2):225–227.
  • Chattopadhyay S, Raychaudhuri U, Chakraborty R. Artificial sweeteners – a review. J Food Sci Technol. 2014;51(4):611–621.
  • Shahriar S, Ahsan T, Khan A, et al. Aspartame, acesulfame K and sucralose-influence on the metabolism of Escherichia coli. Metabol Open. 2020;8:100072.
  • Belton K, Schaefer E, Guiney PD. A review of the environmental fate and effects of Acesulfame-Potassium. Integr Environ Assess Manage. 2020;16(4):421–437.
  • Liu BB, Jian H, Tian JM, et al. Research progress and problem analysis on flavoring and taste masking technology for traditional Chinese medicine. Chinese J Exp Tradit Med Formulae. 2016;22(16):229–234.
  • Wang C, Perumalla SR, Lu R, et al. Sweet berberine. Crystal Growth Des. 2016;16(2):933–939.
  • Ishizaka T, Miyanaga Y, Mukai J, et al. Bitterness evaluation of medicines for pediatric use by a taste sensor. Chem Pharm Bull. 2004;52(8):943–948.
  • Liu RX, Zhang XD, Zhang L, et al. Bitterness intensity prediction of berberine hydrochloride using an electronic tongue and a GA-BP neural network. Exp Ther Med. 2014;7(6):1696–1702.
  • Zhang P, Zhang Y, Gui XJ, et al. Study on superposition rule of bitterness of decoction of Chinese materia medica based on traditional human taste panel method and electronic tongue method. Chinese Tradit Herbal Drugs. 2021;52(03):653–668.
  • Choi Du H, Kim NA, Nam TS, et al. Evaluation of taste-masking effects of pharmaceutical sweeteners with an electronic tongue system. Drug Dev Ind Pharm. 2014;40(3):308–317.
  • Drašković M, Medarević D, Aleksić I, et al. In vitro and in vivo investigation of taste-masking effectiveness of eudragit E PO as drug particle coating agent in orally disintegrating tablets. Drug Dev Ind Pharm. 2017;43(5):723–731.
  • Liu RX, Zhang XF, Li XL, et al. Drug evaluation of bitterness intensity by three kinds of THTPM. Chinese J Exp Tradit Med Formulae. 2013;19(20):118–122.
  • Schiffman SS, Booth BJ, Losee ML, et al. Bitterness of sweeteners as a function of concentration. Brain Res Bull. 1995;36(5):505–513.
  • Kang BY, Liu RX, Meng XL, et al. A comprehensive evaluation of the masking effect of traditional Chinese medicine companion based on ISEM and FSEM. Chinese J New Drugs. 2016;25(12):1385–1390.
  • Liu RX, Wang YL, Zhang Y, et al. Establishment of elimination method of outliers based on Grubbs rule and MATLAB language and its application in evaluating drug bitterness. China Pharmacy. 2019;30(2):176–182.
  • Zhang W, Li G, Xiao C, et al. Mesoporous silica carrier-based composites for taste-masking of bitter drug: fabrication and palatability evaluation. AAPS PharmSciTech. 2022;23(2):75.
  • Li S, Zhang Y, Khan AR, et al. Quantitative prediction of the bitterness of atomoxetine hydrochloride and taste-masked using hydroxypropyl-β-cyclodextrin: a biosensor evaluation and interaction study. Asian J Pharm Sci. 2020;15(4):492–505.
  • Di Pizio A, Niv MY. Promiscuity and selectivity of bitter molecules and their receptors. Bioorg Med Chem. 2015;23(14):4082–4091.
  • Li XL, Chen PJ, Gui XJ, et al. Application of electronic tongue in pattern study about bitterness inhibition by hydroxypropyl-β-cyclodextrin. Chinese Tradit Herbal Drugs. 2017;48(20):4235–4244.
  • Li XL, Zhang Y, Chen PJ, et al. Study on superposition law of drug bitterness based on tongue taste evaluation and electronic tongue evaluation. China J Chinese Mater Med. 2019;44(23):5134–5142.
  • Cheung LC, Nguyen M, Tang E, et al. Taste evaluation of a novel midazolam tablet for pediatric patients: in vitro drug dissolution, in vivo animal taste aversion and clinical taste perception profiles. Int J Pharm. 2018;535(1–2):194–200.
  • Liu Y, Wu X, Tahara Y, et al. A quantitative method for acesulfame K using the taste sensor. Sensors. 2020;20(2):400.
  • Kuhn C, Bufe B, Winnig M, et al. Bitter taste receptors for saccharin and acesulfame K. J Neurosci. 2004;24(45):10260–10265.
  • Lossow K, Hübner S, Roudnitzky N, et al. Comprehensive analysis of mouse bitter taste receptors reveals different molecular receptive ranges for orthologous receptors in mice and humans. J Biol Chem. 2016;291(29):15358–15377.