In vivo and in vitro evaluation of pulmonary administration of itraconazole nanostructured lipid carriers for pulmonary aspergillosis

References

• Walsh TJ, Anaissie EJ, Denning DW, et al. Treatment of aspergillosis: clinical practice guidelines of the infectious diseases society of america. Clin Infect Dis. 2008;46(3):327–360.
   PubMed Web of Science ®Google Scholar
• Meidani M, Hakamifard A, Sarrami AH. Resolution of aspergillosis in neuroimaging of an immunocompromised patient with pulmonary and cerebral lesions. Asian J Neurosurg. 2016;11(4):456.
   PubMedGoogle Scholar
• Lopez-Medrano F, Fernandez-Ruiz M, Silva JT, et al. Clinical presentation and determinants of mortality of invasive pulmonary aspergillosis in kidney transplant recipients: a multinational cohort study. Am J Transplant. 2016;16(11):3220–3234.
   PubMed Web of Science ®Google Scholar
• Swoboda-Kopeć E, Sikora M, Piskorska K, et al. Diagnosis of invasive pulmonary aspergillosis. Adv Exp Med Biol. 2016;944:27–33.
   Web of Science ®Google Scholar
• Chen S, Sun KY, Feng XW, et al. Efficacy and safety of itraconazole use in infants. World J Pediatr. 2016;12(4):399–407.
   PubMed Web of Science ®Google Scholar
• Elphick HE, Southern KW. Antifungal therapies for allergic bronchopulmonary aspergillosis in people with cystic fibrosis. Cochrane Database Syst Rev. 2016;11(11):CD002204.
   PubMedGoogle Scholar
• Lewis RE, Prince RA, Chi J, et al. Itraconazole preexposure attenuates the efficacy of subsequent amphotericin B therapy in a murine model of acute invasive pulmonary aspergillosis. Antimicrob Agents Chemother. 2002;46(10):3208–3214.
   PubMed Web of Science ®Google Scholar
• Caillot D, Bassaris H, McGeer A, et al. Intravenous itraconazole followed by oral itraconazole in the treatment of invasive pulmonary aspergillosis in patients with hematologic malignancies, chronic granulomatous disease, or AIDS. Clin Infect Dis. 2001;33(8):e83–e90.
   PubMed Web of Science ®Google Scholar
• Mohanty B, Majumdar DK, Mishra SK, et al. Development and characterization of itraconazole-loaded solid lipid nanoparticles for ocular delivery. Pharm Dev Technol. 2015;20(4):458–464.
   PubMed Web of Science ®Google Scholar
• Pardeike J, Weber S, Haber T, et al. Development of an itraconazole-loaded nanostructured lipid carrier (NLC) formulation for pulmonary application. Int J Pharm. 2011;419(1–2):329–338.
   PubMed Web of Science ®Google Scholar
• Marr KA, Carter RA, Crippa F, et al. Epidemiology and outcome of mould infections in hematopoietic stem cell transplant recipients. Clin Infect Dis. 2002;34(7):909–917.
   PubMed Web of Science ®Google Scholar
• Xu C, Tian H, Wang P, et al. The suppression of metastatic lung cancer by pulmonary administration of polymer nanoparticles for co-delivery of doxorubicin and survivin siRNA. Biomater Sci. 2016;4(11):1646–1654.
   PubMed Web of Science ®Google Scholar
• Mangino JE, Pappas PG. Itraconazole for the treatment of histoplasmosis and blastomycosis. Int J Antimicrob Agents. 1995;5(4):219–225.
   PubMed Web of Science ®Google Scholar
• De Beule K. Itraconazole: pharmacology, clinical experience and future development. Int J Antimicrob Agents. 1996;6(3):175–181.
   PubMed Web of Science ®Google Scholar
• Deshpande TM, Shi H, Pietryka J, et al. Investigation of polymer/surfactant interactions and their impact on itraconazole solubility and precipitation kinetics for developing Spray-Dried amorphous solid dispersions. Mol Pharm. 2018;15(3):962–974.
   PubMedGoogle Scholar
• Huang Z, Lin L, McGoverin C, et al. Dry powder inhaler formulations of poorly water-soluble itraconazole: a balance between in-vitro dissolution and in-vivo distribution is necessary. Int J Pharm. 2018;551(1–2):103–110.
   PubMedGoogle Scholar
• Thakkar HP, Khunt A, Dhande RD, et al. Formulation and evaluation of itraconazole nanoemulsion for enhanced oral bioavailability. J Microencapsul. 2015;32(6):559–569.
   PubMed Web of Science ®Google Scholar
• De Smet L, Saerens L, De Beer T, et al. Formulation of itraconazole nanococrystals and evaluation of their bioavailability in dogs. Eur J Pharm Biopharm. 2014;87(1):107–113.
   PubMed Web of Science ®Google Scholar
• Solanki NG, Lam K, Tahsin M, et al. Effects of surfactants on Itraconazole-HPMCAS solid dispersion prepared by hot-melt extrusion I: miscibility and drug release. J Pharm Sci. 2019;108(4):1453–1465.
   PubMed Web of Science ®Google Scholar
• Thiry J, Kok MG, Collard L, et al. Bioavailability enhancement of itraconazole-based solid dispersions produced by hot melt extrusion in the framework of the three Rs rule. Eur J Pharm Sci. 2017;99:1–8.
   PubMed Web of Science ®Google Scholar
• Botros SR, Hussein AK, Mansour HF. A novel nanoemulsion intermediate gel as a promising approach for delivery of itraconazole: design, in vitro and ex vivo appraisal. AAPS PharmSciTech. 2020;21(7):272.
   PubMed Web of Science ®Google Scholar
• Pardeike J, Weber S, Zarfl HP, et al. Itraconazole-loaded nanostructured lipid carriers (NLC) for pulmonary treatment of aspergillosis in falcons. Eur J Pharm Biopharm. 2016;108:269–276.
   PubMed Web of Science ®Google Scholar
• Rojekar S, Fotooh Abadi L, Pai R, et al. Multi-organ targeting of HIV-1 viral reservoirs with etravirine loaded nanostructured lipid carrier: an in-vivo proof of concept. Eur J Pharm Sci. 2021;164:105916.
   PubMed Web of Science ®Google Scholar
• Iqbal MA, Md S, Sahni JK, et al. Nanostructured lipid carriers system: recent advances in drug delivery. J Drug Target. 2012;20(10):813–830.
   PubMed Web of Science ®Google Scholar
• Rojekar S, Pai R, Abadi LF, et al. Dual loaded nanostructured lipid carrier of nano-selenium and etravirine as a potential anti-HIV therapy. Int J Pharm. 2021;607:120986.
   PubMedGoogle Scholar
• Pai RV, Vavia PR. Chitosan oligosaccharide enhances binding of nanostructured lipid carriers to ocular mucins: effect on ocular disposition. Int J Pharm. 2020;577:119095.
   PubMedGoogle Scholar
• Patil TS, Deshpande AS. Nanostructured lipid carriers-based drug delivery for treating various lung diseases: a state-of-the-art review. Int J Pharm. 2018;547(1-2):209–225.
   PubMedGoogle Scholar
• Vitorino C, Almeida A, Sousa J, et al. Passive and active strategies for transdermal delivery using co-encapsulating nanostructured lipid carriers: in vitro vs. in vivo studies. Eur J Pharm Biopharm. 2014;86(2):133–144.
   PubMed Web of Science ®Google Scholar
• Tang J, Ji H, Ren J, et al. Solid lipid nanoparticles with TPGS and brij 78: a co-delivery vehicle of curcumin and piperine for reversing P-glycoprotein-mediated multidrug resistance in vitro. Oncol Lett. 2017;13(1):389–395.
   PubMed Web of Science ®Google Scholar
• Ji P, Yu T, Liu Y, et al. Naringenin-loaded solid lipid nanoparticles: preparation, controlled delivery, cellular uptake, and pulmonary pharmacokinetics. Drug Des Devel Ther. 2016;10:911–925.
   PubMed Web of Science ®Google Scholar
• Yamamoto A, Tanaka H, Okumura S, et al. Evaluation of insulin permeability and effects of absorption enhancers on its permeability by an in vitro pulmonary epithelial system using xenopus pulmonary membrane. Biol Pharm Bull. 2001;24(4):385–389.
   PubMed Web of Science ®Google Scholar
• Maji R, Omolo CA, Agrawal N, et al. pH-Responsive Lipid-Dendrimer hybrid nanoparticles: an approach to target and eliminate intracellular pathogens. Mol Pharm. 2019;16(11):4594–4609.
   PubMedGoogle Scholar
• Devel L, Almer G, Cabella C, et al. Biodistribution of nanostructured lipid carriers in mice atherosclerotic model. Molecules. 2019;24(19):3499.
   PubMed Web of Science ®Google Scholar
• Davis JL, Salmon JH, Papich MG. Pharmacokinetics and tissue distribution of itraconazole after oral and intravenous administration to horses. Am J Vet Res. 2005;66(10):1694–1701.
   PubMed Web of Science ®Google Scholar
• Fathi HA, Allam A, Elsabahy M, et al. Nanostructured lipid carriers for improved oral delivery and prolonged antihyperlipidemic effect of simvastatin. Colloids Surf B Biointerfaces. 2018;162:236–245.
   PubMed Web of Science ®Google Scholar
• Kim BS, Na YG, Choi JH, et al. The improvement of skin whitening of phenylethyl resorcinol by nanostructured lipid carriers. Nanomaterials. 2017;7(9):241.
   Web of Science ®Google Scholar
• Wang Z, Wang J, Yang S, et al. Construction and in vitro/in vivo evaluation of 17-allylamino-17-demethoxygeldanamycin (17AAG)-loaded PEGylated nanostructured lipid carriers. Drug Dev Ind Pharm. 2016;42(1):91–98.
   PubMed Web of Science ®Google Scholar
• Devkar TB, Tekade AR, Khandelwal KR. Surface engineered nanostructured lipid carriers for efficient nose to brain delivery of ondansetron HCl using delonix regia gum as a natural mucoadhesive polymer. Colloids Surf B Biointerfaces. 2014;122:143–150.
   PubMed Web of Science ®Google Scholar
• Lim WM, Rajinikanth PS, Mallikarjun C, et al. Formulation and delivery of itraconazole to the brain using a nanolipid carrier system. Int J Nanomedicine. 2014;9:2117–2126.
   PubMed Web of Science ®Google Scholar
• Shiva G, Somaye M, Reza JM. Improved photostability, reduced skin permeation and irritation of isotretinoin by solid lipid nanoparticles. Acta Pharm. 2012;62(4):547–562.
   PubMed Web of Science ®Google Scholar
• Abdolahpour S, Toliyat T, Omidfar K, et al. Targeted delivery of doxorubicin into tumor cells by nanostructured lipid carriers conjugated to anti-EGFRvIII monoclonal antibody. Artif Cells Nanomed Biotechnol. 2018;46:(1):89–94.
   PubMed Web of Science ®Google Scholar
• Natarajan JV, Nugraha C, Ng XW, et al. Sustained-release from nanocarriers: a review. J Control Release. 2014;193:122–138.
   PubMed Web of Science ®Google Scholar
• Rundfeldt C, Steckel H, Scherliess H, et al. Inhalable highly concentrated itraconazole nanosuspension for the treatment of bronchopulmonary aspergillosis. Eur J Pharm Biopharm. 2013;83(1):44–53.
   PubMed Web of Science ®Google Scholar
• Pal P, Thakur RS, Ray S, et al. Design and development of a safer non-invasive transungual drug delivery system for topical treatment of onychomycosis. Drug Dev Ind Pharm. 2015;41(7):1095–1099.
   PubMed Web of Science ®Google Scholar
• El-Sabrout K, Aggag S, de Souza JBF. Some recent applications of rabbit biotechnology – a review. Anim Biotechnol. 2020;31(1):76–80.
   PubMed Web of Science ®Google Scholar
• Tang J, Wei H, Liu H, et al. Pharmacokinetics and biodistribution of itraconazole in rats and mice following intravenous administration in a novel liposome formulation. Drug Deliv. 2010;17(4):223–230.
   PubMed Web of Science ®Google Scholar