Metabolite profiling coupled with statistical analyses for potential high-throughput screening of quantitative resistance to fusarium head blight in wheat

References

• Abu-Nada , Y. , Kushalappa , A. C. , Marshall , W. D. , Al-Mughrabi , K. and Murphy , A. 2007 . Temporal dynamics of pathogenesis-related metabolites and their plausible pathways of induction in potato leaves following inoculation with Phytophthora infestans . Eur. J. Plant Pathol. , 118 : 375 – 391 .
   Google Scholar
• Anderson , J. A. , Stack , R. W. , Liu , S. , Waldron , B. L. , Fjeld , A. D. , Coyne , C. , Moreno-Sevilla , B. , Fetch , J. M. , Song , Q. J. , Cregan , P. B. and Frohberg , R. C. 2001 . DNA markers for Fusarium head blight resistance QTLs in two wheat populations . Theor. Appl. Genet. , 102 : 1164 – 1168 .
   Web of Science ®Google Scholar
• Bajad , S. , Targolli , J. , Liu , L. F. , Ho , T. H. D. and Wu , R. 1999 . Transgenic approaches to increase dehydration-stress tolerance in plants . Mol. Breed. , 5 : 493 – 503 .
   Google Scholar
• Ban , T. Comparative genetic analysis of FHB-resistant germplasm for wheat improvement . National Fusarium Head Blight Forum Proceedings . December 13-15 2003 , Bloomington, Minn.. pp. 215 – 217 .
   Google Scholar
• Berridge , M. J. and Irvine , R. F. 1989 . Inositol phosphates and cell signaling . Nature , 341 : 197 – 205 . London
   PubMed Web of Science ®Google Scholar
• Broeckling , C. D. , Reddy , I. R. , Duran , A. L. , Zhao , X. and Sumner , L. W. 2006 . MET-IDEA: data extraction tool for mass spectrometry-based metabolomics . Anal. Chem. , 78 : 4334 – 4341 .
   PubMed Web of Science ®Google Scholar
• Daoubi , M. , Durán-Patrón , R. , Hmamouchi , M. , Hernández-Galán , R. , Benharref , A. and Collado , I. G. 2004 . Screening study for potential lead metabolites for natural product-based fungicides: I. Synthesis and in vitro evaluation of coumarins against Botrytis cinerea . Pest Manage. Sci. , 60 : 927 – 932 .
   PubMed Web of Science ®Google Scholar
• Dixon , A. R. , Achnine , L. , Kotap , J. , Liu , C. J. , Reddy , M. S. S. and Wang , L. 2002 . The phenylpropanoid pathway and plant defense–;a genomics perspective . Mol. Plant Pathol. 3 , 371-390
   Google Scholar
• Farmer , E. E. , Weber , H. and Vollenweider , S. 1998 . Fatty acid signaling in Arabidopsis . Planta , 206 : 167 – 174 .
   PubMedGoogle Scholar
• Fiehn , O. , Kopka , J. , Dörmann , P. , Altmann , T. , Trethewey , R. N. and Willmitzer , L. 2000 . Metabolite profiling for plant functional genomics . Nature Biotechnol , 18 : 1157 – 1161 .
   PubMed Web of Science ®Google Scholar
• Gilbert , J. and Tekauz , A. 2000 . Recent development in research on fusarium head blight of wheat in Canada . Can. J. Plant Pathol. , 22 : 1 – 8 .
   Web of Science ®Google Scholar
• Gonzalez , H. J. L. , Del Blanco , A. , Ali , S. , Berzonsky , W. A. and Kianian , S. F. Wanshuibai: a hexaploid wheat resistant to the spread of fusarium head blight. 2003 . National Fusarium Head Blight Forum Proceedings . December 13-15 2003 , Bloomington, Minn.. pp. 14 – 17 .
   Google Scholar
• Goodacre , R. , Vaidyanathan , S. , Dunn , W. B. , Harrigan , G. G. and Kell , D. B. 2004 . Metabolomics by numbers: acquiring and understanding global metabolite data . Trends Biotechnol. , 22 : 245 – 252 .
   PubMed Web of Science ®Google Scholar
• Hamzehzarghani , H. , Kushalappa , A. C. , Dion , Y. , Rioux , S. , Comeau , A. , Yaylayan , V. , Marshall , W. D. and Mather , D. E. 2005 . Metabolite profiling and factor analysis to discriminate quantitative resistance in wheat cultivars against fusarium head blight . Physiol. Mol. Plant Pathol. , 66 : 119 – 133 .
   Web of Science ®Google Scholar
• Johnson , D. E. 1998 . Applied multivariate methods for data analysts , New York : Duxbury Press .
   Google Scholar
• Keurentjes , J. J. B. , Fu , J. , Ric de Vos , C. H. , Lommen , A. , Hall , R. D. , Bino , R. J. , van der Plas , L. H. W. , Jansen , R. C. , Vreugdenhil , D. and Koornneef , M. 2006 . The genetics of plant metabolism . Nature Genet. , 38 : 842 – 849 .
   PubMed Web of Science ®Google Scholar
• Kolb , F. L. , Bai , G. H. , Muehlbauer , G. J. , Anderson , J. A. , Smith , K. P. and Fedak , G. 2001 . Host plant resistance genes for fusarium head blight: mapping and manipulation with molecular markers . Crop Sci. , 41 : 611 – 619 .
   Web of Science ®Google Scholar
• Kopka , J. 2006 . “ Gas chromatography mass spectrometry. Biotechnology in agriculture and forestry ” . In Plant metabolomics , Edited by: Widholm , J. M. , Nagata , T. and Lorz , H. Vol. 57 , 3 – 20 . Berlin : Springer-Verlag .
   Google Scholar
• Kopka , J. , Schauer , N. , Krueger , S. , Birkemeyer , C. , Usadel , B. , Bergmuller , E. , Dormann , P. , Weckwerth , W. , Gibon , Y. , Stitt , M. , Willmitzer , L. , Fernie , A. R. and Steinhauser , D. 2005 . GMD@CSBDB: the Golm metabolome database . Bioinformatics , 21 : 1635 – 1638 .
   PubMed Web of Science ®Google Scholar
• Lemmens , M. , Scholz , U. , Berthiller , F. , Dall'Asta , C. , Koutnik , A. , Schuhmacher , R. , Adam , G. , Buerstmayr , H. , Mesterházy , Á. , Krska , R. and Ruckenbauer , P. 2005 . The ability to detoxify the mycotoxin deoxynivalenol colocalizes with a major quantitative trait locus for fusarium head blight resistance in wheat . Mol. Plant-Microbe Interact. , 18 : 1318 – 1324 .
   PubMed Web of Science ®Google Scholar
• McKeehen , J. D. , Busch , R. H. and Fulcher , R. G. 1999 . Evaluation of wheat (Triticum aestivum L.) phenolic acids during grain development and their contribution to Fusarium resistance . J. Agric. Food Chem. , 47 : 1476 – 1482 .
   PubMed Web of Science ®Google Scholar
• Mesterhazy , A. 2003 . “ Breeding wheat for FHB ” . In Fusarium head blight of wheat and barley , Edited by: Leonard , K. J. and Bushnell , W. R. 211 – 240 . St. Paul, Minn : American Phytopathological Society Press .
   Google Scholar
• Miedaner , T. 1997 . Breeding wheat and rye for resistance to fusarium diseases . Plant Breed. , 116 : 201 – 220 .
   Web of Science ®Google Scholar
• Muthukrishnan , S. , Liang , G. H. , Trick , H. N. and Gill , B. S. 2001 . Pathogenesis-related proteins and their genes in cereals . Plant Cell Tissue Organ Cult. , 64 : 93 – 114 .
   Web of Science ®Google Scholar
• Okazaki , Y. , Isobe , T. , Iwata , Y. , Matsukawa , T. , Matsuda , F. , Miyagawa , H. , Ishihara , A. , Nishioka , T. and Iwamura , H. 2004 . Metabolism of avenanthramide phytoalexins in oats . Plant J. , 39 : 560 – 572 .
   Google Scholar
• Pieterse , C. M. J. and Van Loon , L. 1999 . Salicylic acid-independent plant defense pathways . Trends Plant Sci. , 4 : 52 – 58 .
   PubMed Web of Science ®Google Scholar
• Prats , E. , Bazzalo , M. E. , Léon , A. and Jorrín , J. V. 2005 . Fungitoxic effect of scopolin and related coumarins on Sclerotinia sclerotiorum, a way to overcome sunflower head rot . Euphytica , 147 : 451 – 460 .
   Google Scholar
• Pritsch , C. , Muehlbauer , G. J. , Bushnell , W. R. , Somers , D. A. and Vance , C. P. 2000 . Fungal development and induction of defense response genes during early infection of wheat spikes by Fusarium graminearum . Mol. Plant-Microbe Interact. , 14 : 159 – 169 .
   Google Scholar
• Roessner , U. , Wagner , C. , Kopka , J. , Trethewey , R. N. and Willmitzer , L. 2000 . Simultaneous analysis of metabolites in tuber by gas chromatography - mass spectrometry . Plant J. , 23 : 131 – 142 .
   PubMed Web of Science ®Google Scholar
• Russell , W. R. , Burkitt , M. J. , Provan , G. J. and Chesson , A. 1999 . Structure-specific functionality of plant cell wall hydroxycinnamates . J. Sci. Food Agric. , 79 : 408 – 410 .
   Web of Science ®Google Scholar
• Schauer , N. and Fernie , A. R. 2006 . Plant metabolomics: towards biological function and mechanism . Trends Plant Sci. , 11 : 508 – 516 .
   PubMed Web of Science ®Google Scholar
• Schauer , N. , Semel , Y. , Roessner , U. , Gur , A. , Balbo , I. , Carrari , F. , Pleban , T. , Perez-Melis , A. , Beuedigam , C. , Kopka , J. , Willmitzar , L. , Zamir , D. and Fernie , A. R. 2006 . Comprehensive metabolic profiling and phenotyping of interspecific introgression lines for tomato improvement . Nature Biotechnol. , 24 : 447 – 454 .
   PubMed Web of Science ®Google Scholar
• Schroeder , H. W. and Christensen , J. J. 1963 . Factors affecting resistance of wheat to scab caused by Gibberella zeae . Phytopathology , 53 : 831 – 838 .
   Web of Science ®Google Scholar
• Siranidou , E. , Kang , Z. and Buchenauer , H. 2002 . Studies on symptom development, phenolic metabolites and morphological defense responses in wheat cultivars differing in resistance to fusarium head blight . J. Phytopathol. , 150 : 200 – 208 .
   Web of Science ®Google Scholar
• Steed , A. , Chandler , E. , Thomsett , M. , Gosman , M. , Faur , S. and Nicolson , P. 2005 . Identification of type I resistance to fusarium head blight controlled by a major gene located on chromosome 4A of Triticum macha . Theor. Appl. Genet. , 111 : 521 – 529 .
   PubMed Web of Science ®Google Scholar
• Sumner , L. W. , Mendes , P. and Dixon , R. A. 2003 . Plant metabolomics: large-scale phytochemistry in the functional genomics era . Phytochemistry , 62 : 817 – 836 .
   PubMed Web of Science ®Google Scholar
• Tikunov , Y. , Lommen , A. , Ric de Vos , C. H. , Verhoeven , H. A. , Bino , R. J. , Hall , R. D. and Bovy , A. G. 2005 . A novel approach for nontargeted data analysis for metabolomics, large-scale profiling of tomato fruit volatiles . Plant Physiol. , 139 : 1125 – 1137 .
   PubMed Web of Science ®Google Scholar
• Vorst , O. , De Vos , C. H. R. , Lommen , A. , Staps , R. V. , Visser , R. G. F. , Bino , R. J. and Hall , R. D. 2005 . A non-directed approach to the differential analysis of multiple LC-MS-derived metabolic profiles . Metabolomics , 1 : 169 – 180 .
   Google Scholar
• Wagner , C. , Sefkow , M. and Kopka , J. 2003 . Construction and application of a mass spectral and retention time index database generated from plant GC/EI-TOF-MS metabolic profiles . Phytochemistry , 62 : 887 – 900 .
   PubMed Web of Science ®Google Scholar
• Walker , T. S. , Pal Bais , H. , Halligan , K. M. , Stermitz , F. R. and Vivaco , J. M. 2003 . Metabolite profiling of root exudates of Arabidopsis thaliana . J Agric. Food Chem. , 51 : 2548 – 2554 .
   PubMed Web of Science ®Google Scholar
• Xue , J. J. , Fan , C. Q. , Dong , L. , Yang , S. P. and Yue , J. M. 2004 . Novel antibacterial diterpenoids from Larix chinensis . Chem. Biodivers. , 1 : 1702 – 1707 .
   PubMedGoogle Scholar
• Zadoks , J. C. , Chang , T. T. and Konzak , C. F. 1974 . A decimal code for growth stages of cereals . Weed Res. , 14 : 415 – 421 .
   Web of Science ®Google Scholar
• Zhou , W. , Kolb , F. L. , Yu , J. , Bai , G. , Boze , L. K. and Domier , L. L. 2004 . Molecular characterization of Fusarium head blight resistance in Wangshuibai with simple sequence repeat and amplified fragment length polymorphism markers . Genome , 47 : 1137 – 1143 .
   PubMed Web of Science ®Google Scholar