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Clinical and Experimental Hypertension. Part A: Theory and Practice Volume 10, 1988 - Issue 6
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Proceedings of the Satellite Symposium, New Aspects of Renin Research

Partial Purification of a Prorenin Activating Enzyme in the Aortic Wall

Shiow-Shih TangMolecular and Cellular Vascular Research Laboratory, Division of Vascular Medicine and Atherosclerosis, Brigham and Women's Hospital, Harvard Medical School, Boston, MA02115
&
Victor J. DzauMolecular and Cellular Vascular Research Laboratory, Division of Vascular Medicine and Atherosclerosis, Brigham and Women's Hospital, Harvard Medical School, Boston, MA02115
Pages 1251-1257 | Published online: 23 May 2017

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  • Dzau VJ, Gonzalez D, Kaempfer C, Dubin D, Wintroub BU. Human neutrophils release serine proteases capable of activating prorenin. Circ Res. 1987; 60:595–601.
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  • Fritz LC, Arfsten AA, Dzau VJ, Atlas SA, Baxter JD, Fiddes JC, Shine J, Coffer CL, Kushner P, Ponte PE. characterization of human prorenin expressed in mammalian cells transfected with cloned cDNA. Proc Nat Acad Sci (USA) 1986; 83:4114–4118.
  • Pratt RE, Flynn JA, Hobart PM, Paul M, Dzau VJ. Different secretory pathways of renin from mouse cells transfected with human renin gene. J Biol Chem 1988; 263:3137–3141.
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  • Lilly LS, Pratt RE, Alexander RW, Larson DM, Ellison KE, Gimbrone MA, Dzau VJ. Renin expression by vascular endothelial cells in culture. Circ Res. 1985; 57:312–318.
  • Re RN, Fallon JT, Dzau VJ, Quay S, Haber E. Renin synthesis by canine aortic smooth muscle cells in culture. Life Sciences. 1982; 30:99–106.
  • Kifor I, Dzau VJ. Endothelial renin-angiotensin pathway: Evidence for intracellular synthesis and secretion of angiotensins. Circ Res 1987; 60:3:422–428.
  • Dzau VJ, Ellison KE, Brody T, Ingelfinger J, Pratt RE. A comparative study of the distributions of renin and angiotensin messenger ribonucleic acids in rat and mouse tissues. Endocrinol. 1987; 120:(6)2334–2338
  • Dzau VJ, Roth T, Gonzalez D, Pratt RE, Lilly LS, Phillippe M. Renin activation by membrane-bound enzyme(s) of vascular endothelial. Clin Res 1984; 32:162A.

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