An Overview of The Three Dimensional Structure of Short Spider Toxins

REFERENCES

• Adams M. E., Mintz I. M., Reily M. D., Thanabal V., Bean B. P. Structure and properties of omega-agatoxin IVB, a new antagonist of P-type calcium channels. Mol. Pharmacol. 1993; 44(4)681–618, [PUBMED], [INFOTRIEVE], [CSA]
   PubMed Web of Science ®Google Scholar
• Bernard C., Legros C., Ferrat G., Bischoff U., Marquardt A., Pongs O., Darbon H. Solution structure of hpTX2, a toxin from Heteropoda venatoria spider that blocks Kv4.2 potassium channel. Protein Sci. 2000, 11: 2059–2067, [CSA]
   PubMed Web of Science ®Google Scholar
• Chagot B., Escoubas P., Villegas E., Bernard C., Ferrat G., Corzo G., Lazdunski M., Darbon H. Solution structure of Phrixotoxin 1, a specific peptide inhibitor of Kv4 potassium channels from the venom of the theraphosid spider Phrixotrichus auratus. Protein Sci. 2004, 13: 1197–1208, [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Corzo G., Escoubas P., Stankiewicz M., Pelhate M., Kristensen C. P., Nakajima T. Isolation, synthesis and pharmacological characterization of delta-palutoxins IT, novel insecticidal toxins from the spider Paracoelotes luctuosus (Amaurobiidae). Eur. J. Biochem. 2000; 267(18)5783–5795, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
   PubMedGoogle Scholar
• Corzo G., Escoubas P., Villegas E., Karbat I., Gordon D., Gurevitz M., Nakajima T., Gilles N. A spider toxin that induces a typical effect of scorpion alpha-toxins but competes with beta-toxins on binding to insect sodium channels. Biochemistry 2005, 44: 1542–1549, [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Diochot S., Drici M. D., Moinier D., Fink M., Lazdunski M. Effects of phrixotoxins on the Kv4 family of potassium channels and implications for the role of Ito1 in cardiac electrogenesis. Br. J. Pharmacol. 1999, 126: 251–263, [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Dongling L., Yucheng X., Xia X., Xia X., Shanyun L., Zhonghua L., Qi Z., Meichi W., Xiaocheng G., Songping L. Structure-activity relationships of hainantoxin-IV and structure determination of active and inactive sodium channel blockers. J. Biol. Chem. 2004, 279: 37734–37740, [CSA]
   PubMedGoogle Scholar
• Einhorn V. F., Hamilton R. Letter: transmitter release by red back spider venom. J. Pharm. Pharmacol. 1973; 25(10)824–826, [PUBMED], [INFOTRIEVE], [CSA]
   PubMed Web of Science ®Google Scholar
• Escoubas P., Bernard C., Lambeau G., Lazdunski M., Darbon H. Recombinant production and solution structure of PcT× 1, the specific peptide inhibitor of ASIC1a protongated cation channels. Protein Sci. 2003, 7: 1332–1343, [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Escoubas P., De Weille J. R., Lecoq A., Diochot S., Waldmann R., Champigny G., Moinier D., Menez A., Lazdunski M. Isolation of a tarantula toxin specific for a class of proton-gated Na+ channels. J. Biol. Chem. 2000, 33: 25116–25121, [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Ferrat G., Bernard C., Fremont V., Mullman T. J., Giangiacomo K. M., Darbon H. Structural basis for a-K toxin specificity for K+ channels revealed through the solution structure 1H NMR structures of two noxiustoxin-iberiotoxin chimeras. Biochemisry 2001, 40: 74–83, [CSA]
   PubMedGoogle Scholar
• Festoff B. W. Mechanism of action of neurotoxins. Ann. Clin. Lab. Sci. 1975; 5(5)377–382, [PUBMED], [INFOTRIEVE], [CSA]
   PubMedGoogle Scholar
• Fletcher J. I., Smith R., O'Donoghue S. I., Nilges M., Connor M., Howden M. E. H., Christie M. J., King G. F. The structure of a novel insecticidal neurotoxin, omegaatracotoxin- HV1, from the venom of an Australian funnel web spider. Nat. Struct. Biol. 1997, 4: 559–566, [CSA], [CROSSREF]
   PubMedGoogle Scholar
• Fremont V., Blanc E., Crest M., Martin-Eau Claire M. F., Gola M., Darbon H., Van Rietschoten J. Dipole moments of scorpion toxins direct the interaction towards small- or large-conductance Ca2+-activated K+ channels. Lett. Pep. Sci. 1997, 4: 1–9, [CSA]
   Google Scholar
• Hideo T., Jae K., Hye J. M., Kazuki S., Kenton J. S., Ichio S. Solution structure of hanatoxin1, a gating modifier of voltage-dependent K. channels: common surface features of gating modifier toxins. J. Mol. Biol. 2004, 297: 771–780, [CSA]
   Google Scholar
• Jungo F., Bairoch A. Tox-Prot, the toxin protein annotation program of the Swiss-Prot protein knowledgebase. Toxicon 2005; 45(3)293–301, Epub 2004 Dec 15[PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Lee C. K., Chan T. K., Ward B. C., Howell D. E., Odell G. V. The purification and characterization of a necrotoxin from tarantula, Dugesiella hentzi (Girard), venom. Arch. Biochem. Biophys. 1974; 164(1)341–350, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Leung H. T., Branton W. D., Phillips H. S., Jan L., Byerly L. Spider toxins selectively block calcium currents in Drosophila. Neuron 1989; 3(6)767–772, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Li D., Xiao Y., Hu W., Xie J., Bosmans F., Tytgat J., Liang S. Function and solution structure of hainantoxin-I, a novel insect sodium channel inhibitor from the Chinese bird spider Selenocosmia hainana. FEBS Lett. 2003, 555: 616–622, [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Lu S., Liang S., Gu X. Three-dimensional structure of Selenocosmia huwena lectin-I (ShL-I) from the venom of the spider Selenocosmia huwena by 2D-NMR. J. Protein Chem. 1999; 18(5)609–617, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
   PubMedGoogle Scholar
• Mintz I. M., Venema V. J., Adams M. E., Bean B. P. Inhibition of N- and L-type Ca2+ channels by the spider venom toxin omega-Aga-IIIA. Proc. Natl. Acad. Sci. USA 1991; 88(15)6628–6631, [PUBMED], [INFOTRIEVE], [CSA]
   PubMed Web of Science ®Google Scholar
• Norton R. S., Pallaghy P. K. The cystine knot structure of ion channel toxins and related polypeptides. Toxicon 1998; 36(11)1573–1583, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Omecinsky D. O., Holub K. E., Adams M. E., Reily M. D. Three-dimensional structure analysis of μ-Agatoxins: Further evidence for common motifs among neurotoxins with diverse ion channel Specificities. Biochemistry 1996, 35: 2836–2844, [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Oswald R. E., Suchyna T. M., Mcfeeters R., Gottlieb P., Sachs F. Solution structure of peptide toxins that block mechanosensitive ion channels, to be published [CSA]
   Google Scholar
• Pallaghy P. K., Nielsen K. J., Craik D. J., Norton R. S. A common structural motif incorporating a cystine knot and a triple-stranded betasheet in toxic and inhibitory polypeptides. Protein Sci. 1994; 3(10)1833–1839, [PUBMED], [INFOTRIEVE], [CSA]
   PubMed Web of Science ®Google Scholar
• Peng K., Shu Q., Liu Z., Liang S. Function and solution structure of huwentoxin-IV, a potent neuronal tetrodotoxin (TTX)-sensitive sodium channel antagonist from Chinese bird spider Selenocosmia huwena. J. Biol. Chem. 2002; 6:277(49)47564–47564, [CSA], [CROSSREF]
   Web of Science ®Google Scholar
• Pumplin D. W., McClure W. O. The release of acetylcholine elicited by extracts of black widow spider glands: studies using rat superior cervical ganglia and inhibitors of electrically stimulated release. J. Pharmacol. Exp. Ther. 1977; 201(2)312–319, [PUBMED], [INFOTRIEVE], [CSA]
   PubMed Web of Science ®Google Scholar
• Qu Y., Liang S., Ding J., Liu X., Zhang R., Gu X. Proton nuclear magnetic resonance studies on huwentoxin-I from the venom of the spider Selenocosmia huwena: 2. Threedimensional structure in solution. J. Protein Chem. 1997; 16(6)565–574, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
   PubMedGoogle Scholar
• Rosengren K. J., Wilson D., Daly N. L., Ewood P. F., Craik D. J. Solution structures of the cis- and trans-Pro30 isomers of a novel 38-residue toxin from the venom of Hadronyche Infensa sp. that contains a cystine-knot motif within its four disulfide bonds. Biochemistry, 41(10)3294–3301, [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Salikhov ShI., Tashmukhamedov M. S., Adylbekov M. T., Korneev A. S., Sadykov A. S. Isolation and quaternary structure of the neurotoxin from the venom of the spider Latrodectus tredecimguttatus. Dokl. Akad. Nauk SSSR 1982; 262(2)485–488, [PUBMED], [INFOTRIEVE], [CSA]
   PubMedGoogle Scholar
• Sheumack D. D., Claassens R., Whiteley N. M., Howden M. E. H. FEBS Lett. 1985, 181: 154–156, [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Shu Q., Lu S. Y., Gu X. C., Liang S. P. The structure of spider toxin huwentoxin-II with unique disulfide linkage: evidence for structural evolution. Protein Sci. 2002; 11(2)245–252, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Stapleton A., Blankenship D. T., Ackermann B. L., Chen T. M., Gorder G. W., Manley G. D., Palfreyman M. G., Coutant J. E., Cardin A. D. Curtatoxins. Neurotoxic insecticidal polypeptides isolated from the funnel-web spider Hololena curta. J. Biol. Chem. 1990; 265(4)2054–2059, [PUBMED], [INFOTRIEVE], [CSA]
   PubMed Web of Science ®Google Scholar
• Szeto T. H., Wang X. H., Smith R., Connor M., Christie M. J., Nicholson G. M., King G. F. Isolation of a funnel-web spider polypeptide with homology to mamba intestinal toxin 1 and the embryonic head inducer Dickkopf-1. Toxicon 2000, 38: 429–442, [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Tedford H. W., Fletcher J. I., King G. F. Functional significance of the beta hairpin in the insecticidal neurotoxin omega-atracotoxin-Hv1a. J. Biol. Chem. 2001; 13:276(28)26568–26576, [CSA], [CROSSREF]
   Web of Science ®Google Scholar
• Tedford H. W., Gilles N., Menez A., Doering C. J., Zamponi G. W., King G. F. Scanning mutagenesis of omega-atracotoxin-Hv1a reveals a spatially restricted epitope that confers selective activity against insect calcium channels. J. Biol. Chem. 2004; 279(42)44133–44140, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Wang X., Connor M., Smith R., Maciejewski M. W., Howden M. E., Nicholson G. M., Christie M. J., King G. F. Discovery and characterization of a family of insecticidal neurotoxins with a rare vicinal disulfide bridge. Nat. Struct. Biol. 2000; 7(6)505–513, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
   PubMedGoogle Scholar
• Wang X., Smith R., Fletcher J. I., Wilson H., Wood C. J., Howden M. E. H., King G. F. Structure-function studies of v-atracotoxin, a potent antagonist of insect voltage-gated calcium channels. Eur. J. Biochem. 1999, 264: 488–494, [CSA], [CROSSREF]
   PubMedGoogle Scholar
• Zarayskiy V. V., Balasubramanian G., Bondarenko V. E., Morales M. J. Heteropoda toxin 2 is a gating modifier toxin specific for voltage-gated K(+) channels of the Kv4 family. Toxicon 2005; 45(4)431–442, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
   PubMed Web of Science ®Google Scholar
• Zhu S., Darbon H., Dyason K., Verdonck F., Tytgat J. Evolutionnary origin of inhibitor cystine knot peptides. FASEB J. 2003, 7: 1765–1767, [CSA]
   PubMedGoogle Scholar