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Original Research

The Use of Konjac Glucomannan to Lower Serum Thyroid Hormones in Hyperthyroidism

, MD, , MD & , MD
Pages 663-668 | Received 24 Apr 2005, Accepted 06 Feb 2007, Published online: 14 Jun 2013

REFERENCES

  • Edwards CA: The physiological effects of dietary fiber. In Kritchevsky D, Bonefield C (eds): “Dietary Fiber in Health & Disease.” St. Paul MN: Eagan Pres, pp58– 71,1995 .
  • Mackeown-Eyssen GE, Bright-See E: Dietary factors in colon cancer: international relationships. Nutr Cancer6 :160– 170,1984 .
  • Schneeman BO, Tinker LF: Dietary fiber. Pediatric Nutr42 :825– 838,1995 .
  • Lim BO, Yamada K, Nonaka M, Kuramoto Y, Hung P, Sugano M: Dietary Fibers Modulate Indices of Intestinal Immune Function in Rats. J Nutr127 :663– 667,1997 .
  • Vuksan V, Sievenpiper JL, Xu Z, Wong EY, Jenkins AL, Beljan Zdravkovic U, Leiter LA, Josse RG, Stavro MP: Konjac-Mannan and American ginsing: emerging alternative therapies for type 2 diabetes mellitus. J Am Coll Nutr20 :370S– 380S,2001 .
  • Arvill A, Bodin L: Effect of short-term ingestion of Konjac glucomannan on serum cholesterol in healthy men. Am J Clin Nutr61 :585– 589,1995 .
  • Doi K: Effect of Konjac fibre (glucomannan) on glucose and lipids. Eur J Clin Nutr49 :S190– 197,1995 .
  • Walsh DE, Yaghoubian V, Behfrooz A: Effect of glucomannan on obese patients: A clinical study. Int J Obesity8 :289– 293,1984 .
  • Yamada K, Tokunaga Y, Ikeda A, Okhura K, Mamiya S, Kaku S, Sugano M, Tachibana H: Dietary effect of guar gum and its partially hydrolyzed product on the lipid metabolism and immune function of Sprague-Dawley rats. Biosci Biotechnol Biochem63 :2163– 2167,1999 .
  • Onishi N, Kawamoto S, Nishimura M, Nakano T, Aki T, Shigeta S, Shimizu H, hashimoto K, Ono K: A new immunomodulatory function of low-viscous konjac glucomannan with a small particle size: its oral intake suppresses spontaneously occurring dermatitis in NC/Nga mice. Int Arch Allergy Immunol136 :258– 265,2005 .
  • Cooper DS: Antithyroid drugs. N Engl J Med311 :1353– 1362,1984 .
  • Croxon MS, Hall TD, Nicoloff JT: Combinationdrug therapy for treatment of hyperthyroid Graves’ disease. J Clin Endocrinol Metab45 :623– 630,1977 .
  • Larsen PR, Davies TF: Thyroid physiology and diagnostic evaluation of patients with thyroid disorders. In Larsen PR, Kronenberg HM, Melmed S, Polonsky KS (eds): “Williams Textbook of Endocrinology,” 10th ed. Philadelphia: W.B. Saunders Company, pp331– 373,2002 .
  • Shakir MKM, Michaels RD, Hays HJ, Potter BD: The use of the bile acid sequestrants to lower serum thyroid hormones in iatrogenic hyperthyroidism. Ann of Intern Med118 :112– 113,1993 .
  • Solomon LB, Wartofsky L, Burman KD: Adjunctive cholestyramine therapy for thyrotoxicosis. Clin Endocrinol38 :39– 43,1993 .
  • Mercado M, Mendoza-Zubieta V, Bautista-Osorio R, Espinoza-de los Monteros AL: Treatment of hyperthyroidism with a combination of methimazole and cholestyramine. J Clin Endocrinol Metab81 :3191– 3193,1996 .
  • Nicoloff JT: Physiologic and pathophysiologic implications of hormone binding. In Ingbar S, Braverman L (eds): “Werner's The Thyroid: A Fundemental and Clinical Text,” 5th ed. New York: J.B. Lippincott, pp113– 134,1986 .
  • Ikegami S, Hareda E, Tsuchihashi N, Nagayama S, Nishide E, Innami S: Effect of indigestible polysaccharides on pancreatic exocrine secretion and biliary output. J Nutr Sci Vitaminol30 :515– 523,1984 .
  • Kriyama S, Enishi A, Yoshida A, Sugiyama N, Shimahora H: Hypocholesterolemic activity and molecular weight of konjac mannan. Proc Japan Acad4 :231– 236,1972 .
  • Bergman F, Heedman P, Van der Linden W: Influence of cholestyramine on absorbtion and excretion of thyroxine in Syrian hamsters. Acta Endocrinol (Copenh)53 :256– 263,1966 .
  • Northcutt RC, Stiel JN, Hollifield JW, Stant EG: The influence of cholestyramine on thyroxine absorbtion. JAMA208 :1857– 1861,1969 .
  • Vuksan V, Sievenpiper JL, Owen R, Swilley JA, Spadafora P, Jenkins DJ, Vidgen E, Brighenti F, Josse RG, Leiter LA, Xu Z, Novokmet R: Beneficial effects of viscous dietary fiber from Konjac-mannan in subjects with the insulin resistance syndrome: results of a controlled metabolic trial. Diabetes Care23 :9– 14,2000 .
  • Wu J, Peng SS: Comparison of hypolipidemic effect of refined konjac meal with several common dietary fibers and their mechanisms of action. Biomed Environ Sci10 :27– 37,1997 .
  • Zhang MY, Huang CY, Wang X, Hong JR, Peng SS: The effect of foods containing refined Konjac meal on human lipid metabolism. Biomed Environ Sci3 :99– 105,1990 .
  • Jacob LR: Fiber and colon cancer. Gastroenterol Clin North Am17 :747– 760,1988 .
  • Lim BO, Yamada K, Sugano M: Effect of bile acids and lectins on immunoglobulin production in rat mesenteric lymph node lymphocytes. In Vitro Cell Develop Biol30 :407– 413,1994 .
  • Lim BO, Yamada K, Yoshimura K, Watanabe T, Pham H, Taniguchi S, Sugano M: Free bile acids inhibit IgE production by mouse spleen lymphocytes stimulated by lipopolysaccaharide and interleukins. Biosci Biotech Biochem59 :624– 627,1995 .
  • Prabhakar BS, Bahn RS, Smith TJ. Current perspective on the pathogenesis of Graves’ disease and ophthalmopathy. Endocr Rev24 :802– 35,2003 .
  • Mizutani T, Mitsuoka T: Effect of konjac mannan on spontaneous liver tumorigenesis and fecal flora in C3H/Hc mal emice. Cancer Letters17 :27– 32,1982 .
  • Mizutani T, Mitsuoka T, Nishikawa Y: Influence of dietary konjac mannan on fecal microflora in f344 rats. Proc Japan Acad63 :273– 276,1987 .
  • Gonzalez Canga A, Fernandez Martinez N, Sahagun AM, Garcia Vieitez JJ, Diez Liebana MJ, Calle Pardo AP, Castro Robles LJ, Sierra Vega M: Glucomannan: properties and therapeutic applications. Nutr Hosp19 :45– 50,2004 .
  • Kato K, Matsuda K: Studies on the chemical structure of konjac mannan. Part I. Isolation and characterization of oligosaccharides from the partial acid hydrolizate of mannan. Agric Biol Chem33 :1446– 1453,1969 .
  • Kishida N, Okimasu S, Kamata N: Molecular weight and intrinsic viscosity of konjac gluco-mannan. Agric Biol Chem42 :1645– 1650,1978 .
  • Maekaji K: The mechanism of gelation of konjac mannan. Agric Biol Chem38 :315– 321,1974 .
  • Vuksan V, Jenkins DJ, Spadafora P, Sievenpiper JL, Owen R, Vidgen E, Brighenti F, Josse R, Leiter LA, Bruce-Thompson C: Konjac-mannan (glucomannan) improves glycemia and other associated risk factors for coronary heart disease in type 2 diabetes. A randomized controlled metabolic trial. Diabetes Care22 :913– 919,1999 .

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