131
Views
87
CrossRef citations to date
0
Altmetric
Original Research

Body Size and Serum 25 Hydroxy Vitamin D Response to Oral Supplements in Healthy Older Adults

, MD, , PhD & , MD
Pages 274-279 | Received 08 Nov 2006, Accepted 11 Jun 2007, Published online: 14 Jun 2013

REFERENCES

  • Reichel H, Koeffler H, Norman A: The Role of the vitamin D endocrine system in health and disease. N Engl J Med320 :981– 991,1989 .
  • Boucher B: Inadequate vitamin D status: does it contribute to the disorders comprising syndrome ‘X’? Br J Nutr79 :315– 327,1998 .
  • Sowers MR, Wallace RB, Lemke J: The association of intakes of vitamin D and calcium with blood pressure among women. Am J Clin Nutr42 :135– 142,1985 .
  • Pfeifer M, Begerow B, Nachtigall D, Minne H: Vitamin D and calcium supplementation reduces blood pressure and secondary hyperparathyroidism in elderly women: A prospective, randomized, double-blind study. J Bone Miner Res15 (Suppl):S443 ,1999 .
  • Hypponen E, Laara E, Reunanen A, Jarvelin MR, Virtanen S: Intake of vitamin D and risk of type I diabetes: A birth-cohort study. Lancet358 :1500– 1503,2001 .
  • Peehl D: Vitamin D and prostate cancer risk. Eur Urology35 :392– 394,1999 .
  • Martinez M, Willet W: Calcium, vitamin D, and colorectal cancer: A review of the epidemiologic evidence. Cancer Epidemiol Biomarkers Prev7 :163– 168,1998 .
  • LeBoff M, Kohlmeier L, Hurwitz S, Franklin J, Wright J, Glowacki J: Occult vitamin D deficiency in postmenopausal US women with acute hip fracture. JAMA281 :1505– 1511,1999 .
  • Webb A, Pilbeam C, Hanafin N, Holick M: An evaluation of the relative contributions of exposure to sunlight and of diet to the circulating concentrations of 25-hydroxyvitamin D in an elderly nursing home population in Boston. Am J Clin Nutr51 :1075– 1081,1990 .
  • Thomas M, Lloyd-Jones D, Thadhani R, Shaw AC, Deraska DJ, Kitch BT, Vamvakas EC, Dick IM, Prince RL, Finkelstein JS: Hypovitaminosis D in medical inpatients. N Engl J Med338 :777– 783,1998 .
  • Webb A, Kline L, Holick M: Influence of season and latitude on the cutaneous synthesis of vitamin D3: Exposure to winter sunlight in Boston and Edmonton will not promote vitamin D3 synthesis in human skin. J Clin Endorcinol Metab67 :373– 378,1988 .
  • Harris S, Dawson-Hughes B: Seasonal changes in plasma 25-hydroxyvitamin D concentrations of young American black and white women. Am J Clin Nutr67 :1232– 1236,1998 .
  • Need A, Morris H, Horowitz M, Nordin B: Effects of skin thickness, age, body fat and sunlight on serum 25-hydroxyvitamin D. Am J Clin Nutr58 :882– 885,1993 .
  • Dawson-Hughes B, Harris S, Krall E, Dallal G: Effect of calcium and vitamin D supplementation on bone density in men and women 65 years of age or older. N Engl J Med337 :670– 676,1997 .
  • Chapuy MC, Arlot ME, Duboeuf F, Brun J, Crouzet B, Arnaud S: Vitamin D3 and calcium to prevent hip fractures in elderly women. N Engl J Med327 :1637– 1642,1992 .
  • Lips P, Wiersinga A, van Ginkel FC, Jongen JM, Netelenbos JC, Hackeng W: The effect of vitamin D supplementation on vitamin D status and parathyroid function in elderly subjects. J Clin Endocrinol Metab67 :644– 650,1988 .
  • Teitelbaum SL, Halverson JD, Baates M, Wise L, Haddad J: Abnormalities of circulating 25-OH vitamin D after jejunal bypass for obesity: Evidence of an adaptive response. Ann Intern Med86 :289– 293,1977 .
  • Compston JE, Vedi S, Ledger JE, Webb A, Gazet JC, Pilkington T: Vitamin D status and bone histomorphometry. Am J Clin Nutr34 :2359– 2363,1981 .
  • Rickers H, Christiansen C, Balslev I, Rodbro P: Impairment of vitamin D metabolism and bone mineral content after intestinal bypass surgery. Scand J Gastroenterol19 :184– 189,1984 .
  • Bell NH, Epstein S, Greene A, Shary J, Oexmann MJ, Shaw S: Evidence for alteration of the vitamin D-endocrine system in obese subjects. J Clin Invest76 :370– 373,1985 .
  • Bell NH, Epstein S, Shary J, Greene V, Oexmann MJ, Shaw S: Evidence of a probable role for 25-hydroxyvitamin D in the regulation of calcium metabolism in man. J Bone Miner Res3 :489– 495,1988 .
  • Liel Y, Ulmer E, Shary J, Hollis BW, Bell N: Low circulating vitamin D in obesity. Calcif Tissue Int43 :199– 201,1988 .
  • Wortsman J, Matsuoka L, Chen T, Lu Z, Holick M: Decreased bioavailability of vitamin D in obesity. Am J Clin Nutr72 :690– 693,2000 .
  • Arunabh S, Pollack S, Yeh J, Aloia J: Body fat content and 25-hydroxyvitamin D levels in healthy women. J Clin Endocrinol Metab88 :157– 161,2003 .
  • Dawson-Hughes B, Harris S, Dallal G: Plasma calcidiol, season and serum parathyroid hormone concentrations in healthy elderly men and women. Am J Clin Nutr65 :67– 71,1997 .
  • Barger-Lux MJ, Heaney RP, Dowell S, Chen TC, Holick M: Vitamin D and its major metabolites: serum levels after graded oral dosing in healthy men. Osteoporos Int8 :222– 230,1998 .
  • Flegal KM, Carroll MD, Ogden CL, Johnson C: Prevalence and trends in obesity among US adults, 1999–2000. JAMA288 :1723– 1727,2002 .
  • Preece MA, O'Riordan JL, Lawson DE, Kodicek E: A competitive protein-binding assay for 25-dihydroxycholecalciferol and 25-hydroxyergocalciferol in serum. Clin Chem Acta54 :235– 242,1974 .
  • Goussous R, Song L, Dallal G, Dawson-Hughes B: Lack of effect of calcium intake on the 25-hydroxyvitamin D response to oral vitamin D3. J Clin Endocrinol Metab90 :707– 711,2005 .
  • Scragg R, Holdaway I, Singh V, Metcalf P, Baker J, Dryson E: Serum 25 hydroxyvitamin D3 is related to physical activity and ethnicity but not to obesity in a multicultural workforce. Aust N Z J Med25 :218– 223,1995 .
  • National Institutes of Health: Clinical guidelines on the identification, evaluation and treatment of overweight and obesity in adults - the evidence report. Obes Res6 :51S– 209S,1998 .
  • Janssen I, Katzmarzyk PT, Ross R: Body mass index, waist circumference, and health risk: evidence in support of current National Institutes of Health guidelines. Arch Intern Med162 :2074– 2079,2002 .
  • Mawer EB, Backhouse J, Holman CA, Lumb GA, Stanbury S: The distribution and storage of vitamin D and its metabolites in human tissues. Clin Sci43 :414– 431,1972 .
  • Rosenstreich SJ, Rich C, Volwiler W: Deposition in and release of vitamin D3 from body fat: Evidence for a storage site in the rat. J Clin Invest50 :679– 687,1971 .
  • MacLaughlin JA, Holick M: Aging decreases the capacity of skin to produce vitamin D3. J Clin Invest76 :1536– 1538,1985 .
  • Dawson-Hughes B: Racial/Ethnic considerations in making recommendations for vitamin D for adult and elderly men and women. Am J Clin Nutr80 (Suppl):1763S– 1766S,2004 .
  • Clemens TL, Zhou XY, Myles M, Endres D, Lindsay R: Serum vitamin D2 and vitamin D3 metabolite concentrations and absorption of vitamin D2 in elderly subjects. J Clin Endocrinol Metab63 :656– 660,1986 .
  • Holick MF: Vitamin D requirements for the elderly. Clin Nutr5 :121– 129,1986 .
  • Harris SS, Dawson-Hughes B: Plasma vitamin D and 25OHD responses of young and old men to supplementation with vitamin D3. J Am Coll Nut21 :357– 362,2002 .

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.