Advanced search
Publication Cover
Journal of the American College of Nutrition Volume 34, 2015 - Issue 3
Submit an article Journal homepage
90
Views
20
CrossRef citations to date
0
Altmetric
Original Research

Hepatoprotective and Antioxidant Effects of Wheat, Carrot, and Mango as Nutraceutical Agents against CCl4-Induced Hepatocellular Toxicity

H. M. EbeidFood Science and Technology Department, Faculty of Agriculture, Ain Shams University, Shoubra El-Kheima, Cairo, EGYPT
, PhD,
A. A. Y. GibrielBiochemistry and Molecular Biology Department, Faculty of Pharmacy, The British University in Egypt (BUE), Cairo, EGYPTCorrespondence[email protected]
, PhD,
H. M. A. AL-SayedFood Science and Technology Department, Faculty of Agriculture, Ain Shams University, Shoubra El-Kheima, Cairo, EGYPT
, PhD,
S. A. ElbehairyMedicinal Food Department, National Organization for Drug Control and Research (NODCAR), Giza, EGYPT
, PhD &
E. H. MotaweMedicinal Food Department, National Organization for Drug Control and Research (NODCAR), Giza, EGYPT
, MSc
Pages 228-231 | Received 15 Dec 2013, Accepted 22 Jan 2014, Published online: 03 Feb 2015

REFERENCES

  • Valko M, Leibfritz D, Moncol J, Cronin MT, Mazur M, Telser J: Free radicals and antioxidants in normal physiological functions and human disease. Int J Biochem Cell Biol 39:44–84, 2007.
  • Kawanishi S, Hiraku Y, Oikawa S: Mechanism of guanine-specific DNA damage by oxidative stress and its role in carcinogenesis and aging. Mutat Res 488:65–76, 2001.
  • Beddowes EZ, Faux SP, Chipman JK: Chloroform, carbon tetra chloride and glutathione depletion induce secondary genotoxicity in liver cells via oxidative stress. Toxicology 187:101–115, 2003.
  • Shahidi F, Naczk M: “Phenolics in Food and Nutraceuticals Sources, Applications and Health Effects.” Boca Raton, FL: Routledge, 2004.
  • Shanmugasundaram P, Venkataraman S: Hepatoprotective and antioxidant effects of Hygrophila auriculata (K. Schum) Heine acanthaceae root. extract. J Ethnopharmacol 104:124–128, 2006.
  • Wanasundara UN, Shahidi F: Antioxidant and pro-oxidant activity of green tee extracts in marine oils. Food Chem 63:335–342, 1998.
  • Benavente-Garicia O, Castillo J, Marin FR, Ortuno A, Del Rio JA: Uses and properties of Citrus flavonoids. J Agr Food Chem 45:4505–4515, 1997.
  • Marinova EM, Yanishlieva NV: Inhibited oxidation of lipids. II. Comparison of the antioxidative properties of some hydroxyl derivatives of benzoic and cinnamic acids. Fat Sci Technol 94:428–432, 1992.
  • Yu L, Haley S, Perret J, Harris M: Antioxidant properties of hard winter wheat extracts. Food Chem 78:457–462, 2002.
  • Thompson HJ, Heimendinger J, Diker A, Neill C, Haegele A, Meinecke B, Wolfe P, Sedlack S, Zhu Z, Jiang W: Dietary botanical diversity affects the reduction of oxidative biomarkers in women due to high vegetable and fruit intake. J Nutr 136:2207–2212, 2006.
  • Camila WL, Boroski M, Boeing JS, Aguiar AC, França PB, De Souza NE, Visentainer JV: Chemical characterization of leaves of organically grown carrot (Dacus carota L.) in various stages of development for use as food. Cienc Tecnol Aliment Campinas 31:735–738, 2011.
  • Muruganandan S, Gupta S, Kataria M, Lal J, Gupta PK: Mangiferin protects the streptozotocin-induced oxidative damage to cardiac and renal tissues in rats. Toxicology 176:165–173, 2002.
  • Garrido G, Gonzalez D, Lemus Y, Garcia D, Lodeiro L, Quintero G, Delporte C, Nunez-Selles AJ, Delgado R: In vivo and in vitro anti-inflammatory activity of Mangifera indica L. extract (VIMANG). Pharmacol Res 50:143–149, 2004.
  • SAS. “Statistical Analysis System, SAS Users Guide: Statistics.” Cary, NC: Routledge, 1999.
  • Snedecor GW, Cochran W: “Statistical Methods.” 7th ed. Ames: Routledge, 1980.
  • Yu L, Haley S, Perret J, Harris M, Wilson J, Qian M: Free radical scavenging properties of wheat extracts. J Agr Food Chem 50:1619–1624, 2002.
  • Reda MYM, EL-Tahan NR, El-Hadad AMA: Effect of aqueous extract Mangifera indica leaves, as functional foods. J Appl Sci Res 6:712–721, 2010.
  • Weber LW, Boll M, Stampfl A: Hepatotoxicity and mechanism of action of haloalkanes: carbon tetrachloride as a toxicological model. Crit Review Toxicol 33:105–136, 2003.
  • Gil SA, Ortega RM, Maldonado J: Wholegrain cereals and bread: a duet of the Mediterranean diet for the prevention of chronic diseases. Public Health Nut 14:2316–2322, 2011.
  • Nielsen F, Mikkelsen BB, Nielsen JB, Andersen HR, Grandjean P: Plasma malondialdehyde as biomarker for oxidative stress: reference interval and effects of life-style factors. Clin Chem 43:1209–1214, 1997.
  • Received December 15, 2013; revision accepted January 22, 2014.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.