The Effect of Lycium Barbarum Polysaccharide on the Glucose and Lipid Metabolism: A Systematic Review and Meta-Analysis

References

• Kwok-Fai S O , Xue-Song MI. The pharmacological mechanism of gojizi as herbal medicine as well as food. Chin Bull Life Sci. 2015;27(08):1070–5.
   Google Scholar
• Guo-Hua YU, Pei WX, Sun HJ, Wang, JX, Wang WB, & Juan, LI, Li S, Lu T, Shi YY, Dong L. Neuroprotective effect and relative mechanisms of Lycii fructus polysaccharide. Chin J Exp Tradit Med Formul. 2018;24(09):213–9.
   Google Scholar
• Hu N, Zheng J, Li W, Suo Y. Isolation, stability, and antioxidant activity of anthocyanins from Lycium ruthenicum Murray and Nitraria Tangutorum Bobr of Qinghai-Tibetan Plateau. Sep Sci Technol. 2014;49(18):2897–906. doi:10.1080/01496395.2014.943770.
   Web of Science ®Google Scholar
• Masci A, Carradori S, Casadei MA, Paolicelli P, Petralito S, Ragno R, Cesa S. Lycium barbarum polysaccharides: extraction, purification, structural characterisation and evidence about hypoglycaemic and hypolipidaemic effects. A review. Food Chem. 2018;254:377–89. doi:10.1016/j.foodchem.2018.01.176.
   Web of Science ®Google Scholar
• Kwok SS, Bu Y, Lo AC, Chan TC, So KF, Lai JS. A systematic review of potential therapeutic use of Lycium barbarum polysaccharides in disease. BioMed Res Int. 2019;2019:4615745. doi:10.1155/2019/4615745.
   PubMed Web of Science ®Google Scholar
• Guo XF, Li ZH, Cai H, Li D. The effects of Lycium barbarum L. (L. barbarum) on cardiometabolic risk factors: a meta-analysis of randomized controlled trials. Food Funct. 2017;8(5):1741–8. doi:10.1039/c7fo00183e.
   Web of Science ®Google Scholar
• Kulczyński B, Gramza-Michałowska A. Goji berry (Lycium barbarum): composition and health effects—a review. Pol J Food Nutr Sci. 2016;66(2):67–75. doi:10.1515/pjfns-2015-0040.
   Web of Science ®Google Scholar
• Potterat O. Goji (Lycium barbarum and L. chinense): phytochemistry, pharmacology and safety in the perspective of traditional uses and recent popularity. Planta Med. 2010;76(1):7–19. doi:10.1055/s-0029-1186218.
   PubMed Web of Science ®Google Scholar
• Xing X, Liu F, Xiao J, So KF. Neuro-protective mechanisms of Lycium barbarum. Neuromol Med. 2016;18(3):253–63. doi:10.1007/s12017-016-8393-y.
   Web of Science ®Google Scholar
• Song MK, Salam NK, Roufogalis BD, Huang TH. Lycium barbarum (Goji Berry) extracts and its taurine component inhibit. Biochem Pharmacol. 2011;82(9):1209–18. doi:10.1016/j.bcp.2011.07.089.
   PubMed Web of Science ®Google Scholar
• Xiao J, Xing F, Huo J, Fung ML, Liong EC, Ching YP, Xu A, Chang RCC, So KF, Tipoe GL, et al. Lycium barbarum polysaccharides therapeutically improve hepatic functions in non-alcoholic steatohepatitis rats and cellular steatosis model. Sci Rep. 2014;4(1):5587. doi:10.1038/srep05587.
   PubMedGoogle Scholar
• Luo Q, Cai Y, Yan J, Sun M, Corke H. Hypoglycemic and hypolipidemic effects and antioxidant activity of fruit extracts from Lycium barbarum. Life Sci. 2004;76(2):137–49. doi:10.1016/j.lfs.2004.04.056.
   Web of Science ®Google Scholar
• Cai HZ, Liu FK, Hui-Xia LU, Guo F, Li-Jie HU, & Han C, et al. Short-term intervention of Lycium barbarum polysaccharide on type 2 diabetes. Food Sci. 2012;33(13):259–262.
   Google Scholar
• Yang S, Si L, Fan L, Jian W, Pei H, Lin R. Polysaccharide IV from Lycium barbarum L. improves lipid profiles of gestational Diabetes mellitus of pregnancy by upregulating ABCA1 and downregulating sterol regulatory element-binding transcription 1 via miR-33. Front Endocrinol (Switzerland: Lausanne), 2018;9:49.
   Web of Science ®Google Scholar
• Yu DH, Wu JM, Niu AJ. Health-promoting effect of LBP and healthy Qigong exercise on physiological functions in old subjects. Carbohydr Polym. 2009;75(2):312–6. doi:10.1016/j.carbpol.2008.07.030.
   Web of Science ®Google Scholar
• Amagase H, Sun BX, Borek C. Lycium barbarum (goji) juice improves in vivo antioxidant biomarkers in serum of healthy adults. Nutr Res. 2009;29(1):19–25. doi:10.1016/j.nutres.2008.11.005.
   PubMed Web of Science ®Google Scholar
• Amagase H, Sun BX, Nance DM. Immunomodulatory effects of a standardized Lycium barbarum fruit juice in Chinese older healthy human subjects. J Med Food. 2009;12(5):1159–65. doi:10.1089/jmf.2008.0300.
   PubMed Web of Science ®Google Scholar
• Guyatt GH, Sackett DL, Sinclair JC, Hayward R, Cook DJ, Cook RJ. Users' guides to the medical literature. IX. A method for grading health care. JAMA. 1995;274(22):1800–4. doi:10.1001/jama.274.22.1800.
   Web of Science ®Google Scholar
• Lee YH. An overview of meta-analysis for clinicians. Korean J Intern Med. 2018;33(2):277–83. doi:10.3904/kjim.2016.195.
   PubMed Web of Science ®Google Scholar
• Xia H, Tang H, Wang F, Yang X, Wang Z, Liu H, Pan D, Wang S, Sun G. Metabolic effects of dietary supplementation of Lycium barbarum polysaccharides on serum and urine metabolomics in a young healthy male population. J Funct Foods. 2018;46:440–8. doi:10.1016/j.jff.2018.04.060.
   Web of Science ®Google Scholar
• Fukuda Y, Hashimoto Y, Hamaguchi M, Fukuda T, Nakamura N, Ohbora A, Kato T, Kojima T, Fukui M. Triglycerides to high-density lipoprotein cholesterol ratio is an independent predictor of incident fatty liver; a population-based cohort study. Liver Int. 2016;36(5):713–20. doi:10.1111/liv.12977.
   PubMed Web of Science ®Google Scholar
• Wu H-T, He X-J, Hong Y-K, Ma T, Xu Y-P, Li H-H. Chemical characterization of Lycium barbarum polysaccharides and its inhibition against liver oxidative injury of high-fat mice. Int J Biol Macromol. 2010;46(5):540–3. doi:10.1016/j.ijbiomac.2010.02.010.
   PubMed Web of Science ®Google Scholar
• Horton JD, Goldstein JL, Brown MS. SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver. J Clin Invest. 2002;109(9):1125–31. doi:10.1172/JCI0215593.
   PubMed Web of Science ®Google Scholar
• Shimano H, Yahagi N, Amemiya-Kudo M, Hasty AH , Osuga JI, Tamura Y, Shionoiri F, Iizuka Y, Ohashi K, Harada K, Gotoda T, Ishibashi S, Yamada N. Sterol regulatory element-binding protein-1 as a key transcription factor for nutritional induction of lipogenic enzyme genes. J Biol Chem. 1999;274(50):35832–9. doi:10.1074/jbc.274.50.35832.
   Web of Science ®Google Scholar
• Li W, Li Y, Wang Q, Yang Y. Crude extracts from Lycium barbarum suppress SREBP-1c expression and prevent diet-induced fatty liver through AMPK activation. Biomed Res Int. 2014;2014:196198.
   Web of Science ®Google Scholar