Structural characterization of an alkali-extracted polysaccharide from Dioscorea opposita Thunb. with initial studies on its anti-inflammatory activity

References

• Huang, R.; Xie, J.; Yu, Y.; Shen, M. Recent Progress in the Research of Yam Mucilage Polysaccharides: Isolation, Structure and Bioactivities. Int. J. Biol. Macromol. 2020, 155, 1262–1269.
   PubMed Web of Science ®Google Scholar
• Ma, F.; Zhang, Y.; Wen, Y.; Yao, Y.; Zhu, J.; Liu, X.; Bell, A.; Tikkanen-Kaukanen, C. Emulsification properties of polysaccharides from Dioscorea opposita Thunb. Food Chem. 2017, 221, 919–925.
   PubMed Web of Science ®Google Scholar
• Li, T.; Teng, H.; An, F.; Huang, Q.; Chen, L.; Song, H. The beneficial effects of purple yam (Dioscorea alata L.) resistant starch on hyperlipidemia in high-fat-fed hamsters. Food Funct. 2019, 10(5), 2642–2650.
   PubMed Web of Science ®Google Scholar
• Ma, F.; Wang, R.; Zhu, J.; Zhang, Y.; Wang, Y.; Hu, W.; Bell, A. E.; Liu, X. Characterisation comparison of polysaccharides from Dioscorea opposita Thunb. growing in sandy soil, loessial soil and continuous cropping. Int. J. Biol. Macromol. 2019, 126, 776–785.
   PubMed Web of Science ®Google Scholar
• Zhang, Z.; Wang, X.; Liu, C.; Li, J. The degradation, antioxidant and antimutagenic activity of the mucilage polysaccharide from Dioscorea opposita. Carbohydr. Polym. 2016, 150, 227–231.
   PubMed Web of Science ®Google Scholar
• Chen, H.; Sun, J.; Liu, J.; Gou, Y.; Zhang, X.; Wu, X.; Sun, R.; Tang, S.; Kan, J.; Qian, C.; et al. Structural characterization and anti-inflammatory activity of alkali-soluble polysaccharides from purple sweet potato. Int. J. Biol. Macromol. 2019, 131, 484–494.
   PubMed Web of Science ®Google Scholar
• Li, M.; Chen, L.; Chen, S.; Deng, Y.; Zhao, J.; Wang, Y.; Li, S. Non-starch polysaccharide from Chinese yam activated RAW 264.7 macrophages through the Toll-like receptor 4 (TLR4)-NF-κB signaling pathway. J. Funct. Foods 2017, 37, 491–500. DOI: https://doi.org/10.1016/j.jff.2017.08.025.
   Web of Science ®Google Scholar
• Tian, C.; Xu, H.; Li, J.; Han, Z. Characteristics and intestinal immunomodulating activities of water-soluble pectic polysaccharides from Chenpi with different storage periods. J. Sci. Food Agric. 2018, 98(10), 3752–3757.
   PubMed Web of Science ®Google Scholar
• Xu, H.; Zou, S.; Xu, X.; Zhang, L. Anti-tumor effect of beta-glucan from Lentinus edodes and the underlying mechanism. Sci. Rep. 2016, 6, 28802.
   PubMed Web of Science ®Google Scholar
• Meng, F.; Li, Q.; Qi, Y.; He, C.; Wang, C.; Zhang, Q. Characterization and immunoregulatory activity of two polysaccharides from the root of Ilex asprella. Carbohydr. Polym. 2018, 197, 9–16.
   PubMed Web of Science ®Google Scholar
• Liu, X.; Liu, F.; Zhao, S.; Guo, B.; Ling, P.; Han, G.; Cui, Z. Purification of an acidic polysaccharide from Suaeda salsa plant and its anti-tumor activity by activating mitochondrial pathway in MCF-7 cells. Carbohydr. Polym. 2019, 215, 99–107.
   PubMed Web of Science ®Google Scholar
• Li, X.; Gao, W. Y.; Jiang, Q. Q.; Wang, Y. L.; Guo, X. H.; Huang, L. Q. Physicochemical, crystalline, and thermal properties of native, oxidized, acid, and enzyme hydrolyzed Chinese yam (Dioscorea opposite Thunb) starch. Starch-Starke 2011, 63, 616–624.
   Web of Science ®Google Scholar
• Falade, K. O.; Ayetigbo, O. E. Influence of physical and chemical modifications on granule size frequency distribution, fourier transform infrared (FTIR) spectra and adsorption isotherms of starch from four yam (Dioscorea spp.) cultivars. J. Food Sci. Tech. 2021. DOI: https://doi.org/10.1007/s13197-021-05200-7.
   Google Scholar
• Ogunmolasuyi, A. M.; Egwim, E. C.; Adewoyin, M. A.; Nkop, J. E. Effect of phosphoric acid treatment on physicochemical, functional, and structural properties of starch extracted from yam (Dioscorea rotundata). Int. J. Food Prop. 2017, 20(5), 1062–1073. DOI: https://doi.org/10.1080/10942912.2016.1199035.
   Web of Science ®Google Scholar
• Yang, W.; Wang, Y.; Li, X.; Yu, P. Purification and structural characterization of Chinese yam polysaccharide and its activities. Carbohydr. Polym. 2015, 117, 1021–1027.
   PubMed Web of Science ®Google Scholar
• Zhu, Y.; Yang, L.; Zhang, C.; Tian, Y.; Zhang, F.; Li, X. Structural and functional analyses of three purified polysaccharides isolated from Chinese Huaishan-yams. Int. J. Biol. Macromol. 2018, 120, 693–701. DOI: https://doi.org/10.1016/j.ijbiomac.2018.08.143.
   PubMed Web of Science ®Google Scholar
• Xue, H. Y.; Li, J. R.; Liu, Y. G.; Gao, Q.; Wang, X. W.; Zhang, J. W.; Tanokura, M.; Xue, Y. L. Optimization of the ultrafiltration-assisted extraction of Chinese yam polysaccharide using response surface methodology and its biological activity. Int. J. Biol. Macromol. 2019, 121, 1186–1193.
   PubMed Web of Science ®Google Scholar
• Li, Q.; Li, W.; Gao, Q.; Zou, Y. Hypoglycemic effect of Chinese yam (Dioscorea opposita rhizoma) polysaccharide in different structure and molecular weight. J. Food Sci. 2017, 82(10), 2487–2494. DOI: https://doi.org/10.1111/1750-3841.13919.
   PubMed Web of Science ®Google Scholar
• Hou, X.; Liu, J.; Li, Z.; Chang, M.; Guo, M.; Feng, C.; Shi, J. Fruiting body polysaccharides of Hericium erinaceus induce apoptosis in human colorectal cancer cells via ROS generation mediating caspase-9-dependent signaling pathways. Food Funct. 2020, 11(7), 6128–6138.
   PubMed Web of Science ®Google Scholar
• Jia, X.; Gao, M.; Li, M.; Wu, Y.; Zeng, Y.; Xu, C. Molecular characterization of two polysaccharides from Phellinus vaninii Ljup and their cytotoxicity to cancer cell lines. Anticancer. Agents Med. Chem. 2018, 18(9), 1356–1363.
   PubMed Web of Science ®Google Scholar
• Wang, J.; Ma, Z.; Zhang, L.; Fang, Y.; Jiang, F.; Phillips, G. O. Structure and chain conformation of water-soluble heteropolysaccharides from Ganoderma lucidum. Carbohydr. Polym. 2011, 86(2), 844–851. DOI: https://doi.org/10.1016/j.carbpol.2011.05.031.
   Web of Science ®Google Scholar
• Bennek, J. A.; Rolf, D.; Gray, G. R. 1,4-Anhydro-2,3,6-tri-O-methyl-D-glucitol formed as an artifact in the reductive cleavage of permethylated 1,4-linked glucopyranosides. J. Carbohydr. Chem. 1983, 2(4), 385–393. DOI: https://doi.org/10.1080/07328308308057885.
   Web of Science ®Google Scholar
• Ju, Y.; Xue, Y.; Huang, J.; Zhai, Q.; Wang, X. H. Antioxidant Chinese yam polysaccharides and its pro-proliferative effect on endometrial epithelial cells. Int. J. Biol. Macromol. 2014, 66, 81–85.
   PubMed Web of Science ®Google Scholar
• Xu, S.; Xu, X.; Zhang, L. Branching structure and chain conformation of water-soluble glucan extracted from Auricularia auricula-judae. J. Agric. Food Chem. 2012, 60(13), 3498–3506.
   PubMed Web of Science ®Google Scholar
• Hawker, C. J.; Lee, R.; Frechet, J. M. J. One-step synthesis of hyperbranched dendritic polyesters. J. Am. Chem. Soc. 1991, 113(12), 4583–4588. DOI: https://doi.org/10.1021/ja00012a030.
   Web of Science ®Google Scholar
• Wang, B.; Pan, L.; Ma, Z.; Li, Y. Ring-opening polymerization with lewis pairs and subsequent nucleophilic substitution: a promising strategy to well-defined polyethylene-like polyesters without transesterification. Macromolecules 2018, 51(3), 836–845. DOI: https://doi.org/10.1021/acs.macromol.7b02378.
   Web of Science ®Google Scholar
• Jia, X.; Wang, C.; Bai, J.; Yu, J.; Xu, C. Sulfation of the extracellular polysaccharide produced by the king oyster culinary-medicinal mushroom, Pleurotus eryngii (Agaricomycetes), and its antioxidant properties in vitro. Int. J. Med. Mushrooms 2017, 19(4), 355–362. DOI: https://doi.org/10.1615/IntJMedMushrooms.v19.i4.60.
   PubMed Web of Science ®Google Scholar
• Chu, Q.; Jia, R.; Chen, M.; Li, Y.; Yu, X.; Wang, Y.; Chen, W.; Ye, X.; Liu, Y.; Jiang, Y.; Zheng, X. Tetrastigma hemsleyanum tubers polysaccharide ameliorates LPS-induced inflammation in macrophages and Caenorhabditis elegans. Int. J. Biol. Macromol. 2019, 141, 611–621.
   PubMed Web of Science ®Google Scholar
• Du, L.; Li, J.; Zhang, X.; Wang, L.; Zhang, W. Pomegranate peel polyphenols inhibits inflammation in LPS-induced RAW264.7 macrophages via the suppression of MAPKs activation. J. Funct. Foods 2018, 43, 62–69. DOI: https://doi.org/10.1016/j.jff.2018.01.028.
   Web of Science ®Google Scholar
• Liu, Q.; Xu, S.; Li, L.; Pan, T.; Shi, C.; Liu, H.; Cao, M.; Su, W.; Liu, G. In vitro and in vivo immunomodulatory activity of sulfated polysaccharide from Porphyra haitanensis. Carbohydr. Polym. 2017, 165, 189–196.
   PubMed Web of Science ®Google Scholar
• Wu, D.; Tang, C.; Liu, Y.; Li, Q.; Wang, W.; Zhou, S.; Zhang, Z.; Cui, F.; Yang, Y. Structural elucidation and immunomodulatory activity of a β-D-glucan prepared by freeze-thawing from Hericium erinaceus. Carbohydr. Polym. 2019, 222, 114996.
   PubMed Web of Science ®Google Scholar
• Zhong, J.; Qiu, X.; Yu, Q.; Chen, H.; Yan, C. A novel polysaccharide from Acorus tatarinowii protects against LPS-induced neuroinflammation and neurotoxicity by inhibiting TLR4-mediated MyD88/NF-κB and PI3K/Akt signaling pathways. Int. J. Biol. Macromol. 2020, 163, 464–475.
   PubMed Web of Science ®Google Scholar
• Rodriguez-Cabezas, M. E.; Camuesco, D.; Arribas, B.; Garrido-Mesa, N.; Comalada, M.; Bailon, E.; Cueto-Sola, M.; Utrilla, P.; Guerra-Hernandez, E.; Perez-Roca, C.; et al. The combination of fructooligosaccharides and resistant starch shows prebiotic additive effects in rats. Clin. Nutr. 2010, 29(6), 832–839.
   PubMed Web of Science ®Google Scholar
• Priyan, V. V.; Shahnaz, T.; Kunnumakkara, A. B.; Rana, V.; Saravanan, M.; Narayanasamy, S. Anti-inflammatory and biosorption properties of starch nanocrystals in vitro study: cytotoxic and phytotoxic evaluation. J. Clust. Sci. 2021, 32(5), 1419–1430. DOI: https://doi.org/10.1007/s10876-020-01905-5.
   Web of Science ®Google Scholar
• Gutierrez, T. J. Surface and nutraceutical properties of edible films made from starchy sources with and without added blackberry pulp. Carbohydr. Polym. 2017, 165, 169–179.
   PubMed Web of Science ®Google Scholar