Reactions Of 2′-Deoxy-2′-halouridines and O²,2′-Cyclouridine with Lithium Dialkylamides: Formation of 1′,2′-Unsaturated Derivatives

References

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• The isomeric 2′,6-bis-TMS derivative was also formed in 7% yield
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• Crystal data of 10, are as follows: space group P21 (monoclinic), Z, = 2, a = 19.552(5), b = 7.231(2), c = 13.388(1) Å, β = 99.52(1) °, V = 1866.9(8) Å3, Dc , = 1.094 gcm−3
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• In addition to 10, an unstable product was detected by TLC, which decomposed on attempted purification by silica gel column chromatography
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