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Original Articles

New Neplanocin Analogues II. Enzymatic One-Step Synthesis and Antitumor Activity of 6′-(3-sn-Phosphatidyl)Neplanocin a Derivatives

, , , , , , , , & show all
Pages 437-446 | Received 29 Aug 1991, Accepted 07 Nov 1991, Published online: 23 Sep 2006

References

  • Shuto , I. S. , Obara , T. , Toriya , M. , Hosoya , M. , Snoeck , R. , Andrei , G. , Balzarini , J. and De Clercq , E. J. Med. Chem. , submitted for publication. Part
  • Yaginuma , S. , Muto. , N. , Tsujino , M. , Sudate , Y. , Hayashi , M. and Otani , M. 1981 . J. Antibiot. , 34 : 359 – 366 . (b) Hayashi, M.; Yaginuma, S.; Yoshida, H.; Nakatsu, K. J. Antibiot. 198134, 675–680. (c) Hayashi, M.; Yaginuma, S.; Muto, N.; Tsujino, M. Nucleic Acids Res. Symp. Ser., 19808, 65–67. (d) Tsujino, M.; Yaginuma, S.; Fujii, T.; Hayano, K.; Matsuda, T.; Watanabe, T.; Abe, J. Current Chemotherapy and Infectious Disease, Vol 2. The American Society for Microbiology, Washington, DC, 1981, 1559–1561.
  • Hoshi , A. , Yoshida , M. , ligo , M. , Fukukawa , K. and Ueda , T. 1986 . J. Pharmacobio-Dyn. , 9 : 202 – 206 .
  • Shuto , S. , Itoh , H. , Ueda , S. , Imamura , S. , Fukukawa , K. , Tsujino , M. , Matsuda , A. and Ueda , T. 1988 . Chem. Pharm. Bull. , 36 : 209 – 217 . (b) Shuto, S.; Ueda, S.; Imamura, S.; Fukukawa, M.; Matsuda, A.; Ueda, T. Tetrahedron Lett., 198728, 199–202
  • Itoh , H. and Tsujino , M. unpublished result
  • Inaba , M. , Nagashima , K. , Tsukagoshi , S. and Sakurai , Y. 1986 . Cancer Res. , 45 : 1063 – 1067 .
  • Glazer , R. I. , Knode , M. C. , Tseng , C. K. H. , Haines , D. R. and Marquez , V. E. 1986 . Biochem. Pharmacol. , 35 : 4523 – 4527 .
  • The primary hydroxymethyl group of NPA, which is corresponding to 5′-hydroxymethyl group of adenosine, is numbered 6′
  • Compound 2a has been evaluated only for antileukemic activity against P388 leukemia in mice
  • Ramirez , F. , Mandal , S. B. and Marecek , J. F. 1982 . Snythesis , : 402 – 404 . (b) Oltvoort, J. J.; van der Marel, G. A.; van Boeckel, C. A. A.; van Boom, J. H. Recl, Trav, Chim, Pays-Bas, 1983102, 523–525. (c) Welch, C. J.; Chattopadhyaya, J. Nucleic Acids Res. Symp. ser., 198414, 261–262. (d) Lindh, I.; Stawinski, J. Nucleic Acids Res. Symp. ser., 198718, 189–192. (e) Hostetler, K. Y.; Stuhmiller, L. M.; Lenting, H. B. M.; van den Bosch, H. J. Biol. Chem., 1990265, 6112–6117.
  • Shuto , S. , Imamura , S. , Fukukawa , K. and Ueda , T. 1988 . Chem. Pharm. Bull. , 36 : 5020 – 5023 .
  • Ishihara , M. , Nawa , H. and Miyagawa , C. 1990 . Japan Kokai Tokkyo Koho , : 2 – 76890 .
  • Imamura , S. , Matsumura , E. , Misaki , H. and Mutoh , N. 1982 . Japan Kokai Tokkyo Koho , : 58 – 152481 .
  • Shuto , S. Ph. and Thesis , D. 1988 . Sapporo, , Japan : Hokkaido University . Prepared from egg phosphatidylcholine.
  • Homan , E. R. 1972 . Cancer Chemotherapy Reports Part 3 , 3 : 51

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