Acid-Catalyzed Photosubstitution of 5-Fluoro-1,3-Dimethyluracil with Substituted Benzenes

References

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• In view of the ESR study2c,8) and the MO calculation9) for 1[.−] and its protonated derivative, showing that 1[.−] would be difficult to dissociate to 1,3-dimethyluracyl-5-yl radical (8) under acidic conditions, it seems unlikely that the formation of 3 is the result of the coupling of 8, derived from 1[.−] by elimination of fluoride ion (F−), and 2[.+] (Scheme 4). The fact that no formation of 1,3-dimethyluracil (9) was detected may support the above basis. Scheme 4
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