Synthesis of 1,5-Anhydrohexitol Nucleosides as Mimics of AZT, D4T and DDC

References

• De Clercq , E. 1989 . “ Molecular Targets of Chemotherapeutic Agents Against the Human Immunodeficiency Virus ” . In Perspectives in Antiinfective Therapy , Edited by: Jackson , G. G. , Schlumberger , H. D. , Zeiler , J. H. and Zeiler , J. 396 – 418 . Berlin : Springer-Verlag .
   Google Scholar
• De Clercq , E. 1992 . HIV Inhibitors Targeted at the Reverse Transcriptase. . AIDS Res. Hum retroviruses , 8 : 119 – 134 .
   PubMed Web of Science ®Google Scholar
• Herdewijn , P. , Van Aerschot , A. , Balzarini , J. and De Clercq , E. 1989 . “ 2′,3′-Dideoxynucleoside Analogues as Inhibitors of Human Immunodeficiency Virus ” . In New Methods in Drug Research , Edited by: Makriyannis , A. Volume 3 , 103 – 122 . S.A. : J.R. Prous Science Publishers . chapter 7
   Google Scholar
• Verheggen , I. , Van Aerschot , A. , Toppet , S , Snoeck , R. , Janssen , G. , Balzarini , J. , De Clercq , E. and Merdewijn , P. 1993 . Synthesis and Antiherpes Virus Activity of 1,5-Anhydrohexitol Nucleosides. . J. Med. Chem. , 36 : 2033 – 2040 .
   PubMed Web of Science ®Google Scholar
• Mitsunobu , O. 1981 . The use of Diethyl Azodicarboxylate and Triphenylphosphine in Synthesis and Transformation of Natural Products . Synthesis , : 1 – 28 .
   Web of Science ®Google Scholar
• Hansske , F. , Madej , D. and Robins , M. J. 1984 . 2′ and 3′-Ketonucleosides and their Arabino and xylo Reduction Products: Convenient access via Selective Protection and Oxidation of Ribonucleosides . Tetrahedron , 40 : 125 – 135 .
   Web of Science ®Google Scholar
• Garegg , P. and Samuelsson , B. 1978 . Oxidation of Primary and Secondary Alcohols in Partially Protected Sugars with the Chromium Trioxide-Pyridine Complex in the Presence of Acetic Anhydride. . Carbohydr. Res. , 67 : 267 – 270 .
   Web of Science ®Google Scholar
• Herdewijn , P. , Van Aerschot , A. and Kerremans , L. 1989 . Synthesis of nucleosides fluorinated in the sugar moiety. The application of diethylaminosulfur trifluoride to the synthesis of fluorinated nucleosides. . Nucleosides and Nucleotides , 8 : 65 – 96 .
   Web of Science ®Google Scholar
• Barton , D. and Jaszberenyi , J. 1989 . Improved methods for the radical deoxygenation of secondary alcohols. . Tetrahedron Lett. , 30 : 2619 – 2622 .
   Web of Science ®Google Scholar
• Pauwels , R. , Balzarini , J. , Baba , M. , Snoeck , R. , Schols , D. , Herdewijn , P. , Desmyter , J. and De Clercq , E. 1988 . Rapid and automated tetrazolium-based colorimetric assay for the detection of anti-HIV compounds. . J. Virol. Methods , 20 : 309 – 321 .
   PubMed Web of Science ®Google Scholar