Antisense Strategies for Inhibition of Tumor Necrosis Factor-α Synthesis

Gunther Hartmann Medizinische Klinik, Klinikum Innenstadt of the Ludwig-Maximilians-University, y, Germany

Anne Krug Medizinische Klinik, Klinikum Innenstadt of the Ludwig-Maximilians-University, y, Germany

Martin Bidlingmaier Medizinische Klinik, Klinikum Innenstadt of the Ludwig-Maximilians-University, y, Germany

Andreas Eigler Medizinische Klinik, Klinikum Innenstadt of the Ludwig-Maximilians-University, y, Germany

Stefan Endres Medizinische Klinik, Klinikum Innenstadt of the Ludwig-Maximilians-University, y, Germany

REFERENCES

Eigler , A , Sinha , B , Hartmann , G and Endres , S . 1997 . Taming TNF: anti-tumor necrosis factor strategies . Immunol Today , (in press)
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Hartmann , G , Krug , A , Waller-Fontaine , K and Endres , S . 1996a . Oligodeoxynucleotides enhance lipopolysaccharide-stimulated synthesis of tumor necrosis factor: Dependence on phosphorothioate modification and reversal by heparin . Mol Med , 2 : 429
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Hartmann , G , Krug , A , Eigler , A , Moeller , J , Murphy , J , Albrecht , R and Endres , S . 1996b . “ Specific suppression of human tumor necrosis factor-α synthesis by antisense oligodeoxynucleotides ” . In Antisense Nucl Acid Drug Dev in press
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