50
Views
2
CrossRef citations to date
0
Altmetric
Original Articles

Synthesis of 2′-Deoxynucleoside 5′-Methylenebis-(phosphonate)s Using 2-(4-Nitrophenyl)ethyl Methylenebis(phosphonate) as the Phosphonylating Agent.

, &
Pages 1857-1860 | Published online: 22 Aug 2006

REFERENCES

  • Pankiewicz , K. W. , Lesiak , K. and Watanabe , K. A. 1997 . J. Amer. Chem. Soc , 119 : 3691
  • Pankiewicz , K. W. , Lesiak , K. , Zatorski , A. , Goldstein , B. M. , Carr , S. F. , Sochacki , M. , Majumdar , A. , Seidman , M. and Watanabe , K. A. 1997 . J. Med. Chem. , 40 : 1287
  • Yanachkov , I. and Wright , G. E. 1994 . Nucleosides and Nucleotides , 13 : 339 and references herein
  • Davisson , V. J. , Davis , D. R. , Dixit , V. M. and Poulter , C. D. 1987 . J. Org. Chem. , 52 : 1794
  • Reist , E. , Hart , P. A. , Goodman , L. and Baker , B. R. 1961 . J. Org. Chem. , 26 : 2538
  • Kurihara , T. , Nakaijma , Y. and Mitsunobu , O. 1976 . Tetrahedron Lett. , 17 : 2455
  • Saady , M. , Lebau , L. and Mioskowski , C. 1995 . Tetrahedron Lett. , 36 : 2239
  • Saady , M. , Lebau , L. and Mioskowski , C. 1995 . J. Org. Chem. , 60 : 2946
  • Maier , L. 1965 . Helv. Chim. Acta , 48 : 133
  • Nucleosides 3a-d were synthesized from commercially available 2′-deoxy-5′-O-di-metoxytritylthymidine, 2′ -deoxy-5′ -O-dimethoxytrityl-N4-benzoylcytidine, 2′-deoxy-N6-benzoyladenosine, and 2′-deoxy-N2-isobutyrylguanosine by acetylation with acetic anhydride in pyridine followed by removal of dimetoxytrityl group by treatment with 80% acetic acid

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.