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Nucleosides and Nucleotides Volume 18, 1999 - Issue 10
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Original Articles

Synthesis of New Nucleoside Analogues Comprising a Geminal Difluorocyclopropane Moiety as Potential Antiviral/Antitumor Agents

Yao-Ling Qiu Department of Chemistry, Experimental and Clinical Therapeutics Program, Barbara Ann Karmanos Cancer Institute, Wayne State University School of Medicine, Detroit, Michigan, 48201-1379
&
Jiri Zemlicka Department of Chemistry, Experimental and Clinical Therapeutics Program, Barbara Ann Karmanos Cancer Institute, Wayne State University School of Medicine, Detroit, Michigan, 48201-1379
Pages 2285-2300 | Received 21 May 1999, Accepted 11 Aug 1999, Published online: 04 Oct 2006

References

  • Welch , J. T. and Eswarakrishnan , S. 1991 . Fluorine in Bioorganic Chemistry , 220 – 233 . New York : John Wiley & Sons .
  • Herdewijn , P. , Van Aerschot , A. and Kerremans , L. 1989 . Nucleosides & Nucleotides , 8 : 65 – 96 .
  • Huryn , D. M. and Okabe , M. 1992 . Chem. Rev. , 92 : 1745 – 1768 .
  • Hertel , L. W. , Boder , G. B. , Kroin , J. S. , Rinzel , S. M. , Poore , G. A. , Todd , G. C. and Grindey , G. B. 1990 . Cancer Res. , 50 : 4417 – 4422 .
  • Halazy , S. , Ehrhard , A. and Danzin , C. 1991 . J. Am. Chem. Soc. , 113 : 315 – 317 .
  • Casara , P. J. , Kenny , M. T. and Jund , K. C. 1991 . Tetrahedron Lett. , 32 : 3823 – 3826 .
  • Sekiyama , T. , Hatsuya , S. , Tanaka , Y. , Uchiyama , M. , Ono , N. , Iwayama , S. , Oikawa , M. , Suzuki , K. , Okunishi , M. and Tsuji , T. 1998 . J. Med. Chem. , 41 : 1284 – 1298 .
  • Ashton , W. T. , Meurer , L. C. , Cantone , C. L. , Field , A. K. , Hannah , J. , Karkas , J. D. , Liou , R. , Patel , G. F. , Perry , H. C. , Wagner , A. F. , Walton , E. and Tolman , R. L. 1988 . J. Med. Chem. , 31 : 2304 – 2315 .
  • Czernecki , S. , Georgoulis , C. and Provelenghiou , C. 1976 . Tetrahedron Lett. , : 3535 – 3536 .
  • Danishefsky , S. and Regan , J. 1981 . Tetrahedron Lett. , 22 : 3919 – 3922 .
  • Naruta , Y. , Nagai , N. and Maruyama , K. 1983 . Chem. Lett. , : 1383 – 1386 .
  • Corey , E. J. and Venkateswarlu , A. 1972 . J. Am. Chem. Soc. , 94 : 6190 – 6191 .
  • Taguchi , T. , Kurishita , M. , Shibuya , A. and Aso , K. 1997 . Tetrahedron , 53 : 9497 – 9508 .
  • Verheyden , J. P. H. and Moffatt , J. G. 1972 . J. Org. Chem. , 37 : 2289 – 2299 .
  • Qiu , Y.-L. , Ksebati , M. , Ptak , R. G. , Fan , B. Y. , Breitenbach , J. M. , Lin , J.-S. , Cheng , Y.-C. , Kern , E. R. , Drach , J. C. and Zemlicka , J. 1998 . J. Med. Chem. , 41 : 10 – 23 .
  • Qiu , Y.-C. , Ptak , R. G. , Breitenbach , J. M. , Lin , J.-S. , Cheng , Y.-C. , Kern , E. R. , Drach , J. C. and Zemlicka , J. 1998 . Antiviral Chem. Chemother. , 9 : 341 – 352 .
  • Xu , Z.-Q. , Joshi , R. V. and Zemlicka , J. 1995 . Tetrahedron , 51 : 67 – 76 .
  • Jones , B. C. N. M , Silverton , J. V. , Simons , C. , Megati , S. , Nishimura , H. , Maeda , Y. , Mitsuya , H. and Zemlicka , J. 1995 . J. Med. Chem. , 38 : 1397 – 1405 .
  • Koomen , G. J. , Provoost , L. M. , van Maarschalkerwaart , D. A. H. and Willard , N. P. 1992 . Nudeosides & Nudeotides , 11 : 1297 – 1303 .
  • Phadtare , S. , Kessel , D. , Corbett , T. H. , Rents , H. E. , Court , B. A. and Zemlicka , J. 1991 . J. Med. Chem. , 34 : 421 – 429 .
  • Smith , R. C. and Binkley , S. B. 1959 . J Org. Chem. , 24 : 249 – 251 .

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