Invasive Ability of Human Renal Cell Carcinoma Cell Line Caki-2 Is Accelerated by Gamma-Aminobutyric Acid, via Sustained Activation of ERK1/2 Inducible Matrix Metalloproteinases

REFERENCES

• Vogelzang N. J., Stadler W. M. Kidney cancer. Lancet 1998; 352: 1691–1696
   PubMed Web of Science ®Google Scholar
• Yang J. C., Haworth L., Sherry R. M., Hwu P., Schwartzentruber D. J., Topalian S. L., Steinberg S. M., Chen H. X., Rosenberg S. A. A randomized trial of bevacizumab, an anti-vascular endothelial growth factor antibody, for metastatic renal cancer. N. Engl. J. Med. 2003; 349: 427–434
   PubMed Web of Science ®Google Scholar
• Greenlee R. T., Hill-Harmon M. B., Murray T., Thun M. Cancer statistics, 2001. CA Cancer J. Clin. 2001; 51(1)15–36
   PubMed Web of Science ®Google Scholar
• Pantuck A. J., Zisman A., Belldegrun A. S. The changing natural history of renal cell carcinoma. J. Urol. 2001; 166(5)1611–1623
   PubMed Web of Science ®Google Scholar
• Chow W. H., Gridley G., Fraumeni J. F., Järvholm B. Obesity, hypertension, and the risk of kidney cancer in men. N. Engl. J. Med. 2000; 343(18)1305–1311
   PubMed Web of Science ®Google Scholar
• Linehan W. M., Walther M. M., Zbar B. The genetic basis of cancer of the kidney. J. Urol. 2003; 170: 2163–2172, (6 Pt 1)
   PubMed Web of Science ®Google Scholar
• Hoque M. O., Begum S., Topaloglu O., Jeronimo C., Mambo E., Westra W. H., Califano J. A., Sidransky D. Quantitative detection of promoter hypermethylation of multiple genes in the tumor, urine, and serum DNA of patients with renal cancer. Cancer Res. 2004; 64(15)5511–5517
   PubMed Web of Science ®Google Scholar
• Stadler W. M., Rosner G., Small E., Hollis D., Rini B., Zaentz S. D., Mahoney J. Successful Implementation of the Randomized Discontinuation Trial Design: An Application to the Study of the Putative Antiangiogenic Agent Carboxyaminoimidazole in Renal Cell Carcinoma–CALGB 69901. J. Clin. Oncol. 2005; 23(16)3726–3732
   PubMed Web of Science ®Google Scholar
• Jemal A., Tiwari R. C., Murray T., Ghafoor A., Samuels A., Ward E., Feuer E. J., Thun M. J. Cancer statistics, 2004. CA Cancer J. Clin. 2004; 54(1)8–29
   PubMed Web of Science ®Google Scholar
• Gilon P., Remacle C., de Varebeke J., Pauwels G., Hoet J. J. GABA content and localisation of high-affinity GABA uptake during the development of the rat pancreas. Cell. Mol. Biol. (Noisy-le-grand) 1987; 33(5)573–585
   Web of Science ®Google Scholar
• Watanabe M., Maemura K., Kanbara K., Tamayama T., Hayasaki H. GABA and GABA receptors in the central nervous system and other organs. Int. Rev. Cytol. 2002; 213: 1–47
   PubMed Web of Science ®Google Scholar
• Calver A. R., Medhurst A. D., Robbins M. J., Charles K. J., Evans M. L., Harrison D. C., Stammers M., Hughes S. A., Hervieu G., Couve A., Moss S. J., Middlemiss D. N., Pangalos M. N. The expression of GABA(B1) and GABA(B2) receptor subunits in the cNS differs from that in peripheral tissues. Neuroscience 2000; 100(1)155–170
   PubMed Web of Science ®Google Scholar
• Tamayama T., Maemura K., Kanbara K., Hayasaki H., Yabumoto Y., Yuasa M., Watanabe M. Expression of GABA(A) and GABA(B) receptors in rat growth plate chondrocytes: activation of the GABA receptors promotes proliferation of mouse chondrogenic ATDC5 cells. Mol. Cell. Biochem. 2005; 273(1–2)117–126
   PubMed Web of Science ®Google Scholar
• Maemura K., Yamauchi H., Hayasaki H., Kanbara K., Tamayama T., Hirata I., Watanabe M. Gamma-amino-butyric acid immunoreactivity in intramucosal colonic tumors. J. Gastroenterol. Hepatol. 2003; 18(9)1089–1094
   PubMed Web of Science ®Google Scholar
• Klebig C., Seitz S., Arnold W., Deutschmann N., Pacyna-Gengelbach M., Scherneck S., Petersen I. Characterization of γ-aminobutyric acid type A receptor-associated protein, a novel tumor suppressor, showing reduced expression in breast cancer. Cancer Res. 2005; 65(2)394–400
   PubMed Web of Science ®Google Scholar
• Johnson S. K., Haun R. S. The gamma-aminobutyric acid A receptor pi subunit is overexpressed in pancreatic adenocarcinomas. JOP 2005; 6(2)136–142
   PubMedGoogle Scholar
• Azuma H., Inamoto T., Sakamoto T., Kiyama S., Ubai T., Shinohara Y., Maemura K., Tsuji M., Segawa N., Masuda H., Takahara K., Katsuoka Y., Watanabe M. Gamma-aminobutyric acid as a promoting factor of cancer metastasis; induction of matrix metalloproteinase production is potentially its underlying mechanism. Cancer Res. 2003; 63(23)8090–8096
   PubMed Web of Science ®Google Scholar
• Joseph J., Niggemann B., Zaenker K. S., Entschladen F. The neurotransmitter gamma-aminobutyric acid is an inhibitory regulator for the migration of SW 480 colon carcinoma cells. Cancer Res. 2002; 62(22)6467–6469
   PubMed Web of Science ®Google Scholar
• Sun J., Hemler M. E. Regulation of MMP-1 and MMP-2 production through CD147/extracellular matrix metalloproteinase inducer interactions. Cancer Res. 2001; 61(5)2276–2281
   PubMed Web of Science ®Google Scholar
• Boire A., Covic L., Agarwal A., Jacques S., Sherifi S., Kuliopulos A. PAR1 is a matrix metalloprotease-1 receptor that promotes invasion and tumorigenesis of breast cancer cells. Cell 2005; 120(3)303–313
   PubMed Web of Science ®Google Scholar
• Martin J., Eynstone L., Davies M., Steadman R. Induction of metalloproteinases by glomerular mesangial cells stimulated by proteins of the extracellular matrix. J. Am. Soc. Nephrol. 2001; 12(1)88–96
   PubMed Web of Science ®Google Scholar
• Utani A., Momota Y., Endo H., Kasuya Y., Beck K., Suzuki N., Nomizu M., Shinkai H. Laminin alpha 3 LG4 module induces matrix metalloproteinase-1 through mitogen-activated protein kinase signaling. J. Biol. Chem. 2003; 278(36)34483–34490
   PubMed Web of Science ®Google Scholar
• Rolli M., Fransvea E., Pilch J., Saven A., Felding-Habermann B. Activated integrin alphavbeta3 cooperates with metalloproteinase MMP-9 in regulating migration of metastatic breast cancer cells. Proc. Natl. Acad. Sci. U. S. A. 2003; 100(16)9482–9487
   PubMed Web of Science ®Google Scholar
• Fairfax B. P., Pitcher J. A., Scott M. G., Calver A. R., Pangalos M. N., Moss S. J., Couve A. Phosphorylation and chronic agonist treatment atypically modulate GABAB receptor cell surface stability. J. Biol. Chem. 2004; 279(13)12565–12573
   PubMed Web of Science ®Google Scholar
• Semyanov A., Walker M. C., Kullmann D. M. GABA uptake regulates cortical excitability via cell type-specific tonic inhibition. Nat. Neurosci. 2003; 6(5)484–490
   PubMed Web of Science ®Google Scholar
• Ganguly K., Schinder A. F., Wong S. T., Poo M. GABA itself promotes the developmental switch of neuronal GABAergic responses from excitation to inhibition. Cell 2001; 105(4)521–532
   PubMed Web of Science ®Google Scholar
• Köhling R. Neuroscience. GABA becomes exciting. Science 2002; 298(5597)1350–1351
   Google Scholar
• Obrietan K., Gao X. B., Van Den Pol A. N. Excitatory actions of GABA increase BDNF expression via a MAPK-CREB-dependent mechanism–a positive feedback circuit in developing neurons. J. Neurophysiol. 2002; 88(2)1005–1015
   PubMed Web of Science ®Google Scholar
• Roberts S. S., Mori M., Pattee P., Lapidus J., Mathews R., O'Malley J. P., Hsieh Y. C., Turner M. A., Wang Z., Tian Q., Rodland M. J., Reynolds C. P., Seeger R. C., Nagalla S. R. GABAergic system gene expression predicts clinical outcome in patients with neuroblastoma. J. Clin. Oncol. 2004; 22(20)4127–4134
   PubMed Web of Science ®Google Scholar
• Tatsuta M., Iishi H., Baba M., Nakaizumi A., Ichii M., Taniguchi H. Inhibition by gamma-amino-n-butyric acid and baclofen of gastric carcinogenesis induced by N-methyl-N'-nitro-N-nitrosoguanidine in Wistar rats. Cancer Res. 1990; 50(16)4931–4934
   PubMed Web of Science ®Google Scholar
• Nguyen L., Malgrange B., Breuskin I., Bettendorff L., Moonen G., Belachew S., Rigo J. M. Autocrine/paracrine activation of the GABA(A) receptor inhibits the proliferation of neurogenic polysialylated neural cell adhesion molecule-positive (PSA-NCAM+) precursor cells from postnatal striatum. J. Neurosci. 2003; 23(8)3278–3294
   PubMed Web of Science ®Google Scholar
• Mercer B. A., Kolesnikova N., Sonett J., D'Armiento J. Extracellular regulated kinase/mitogen activated protein kinase is up-regulated in pulmonaryemphysema and mediates matrix metalloproteinase-1 induction by cigarette smoke. J. Biol. Chem. 2004; 279(17)17690–17696
   PubMed Web of Science ®Google Scholar
• McCawley L. J., Li S., Wattenberg E. V., Hudson L. G. Sustained activation of the mitogen-activated protein kinase pathway. A mechanism underlying receptor tyrosine kinase specificity for matrix metalloproteinase-9 induction and cell migration. J. Biol. Chem. 1999; 274(7)4347–4353
   Google Scholar
• Reunanen N., Li S. P., Ahonen M., Foschi M., Han J., Kähäri V. M. Activation of p38 alpha MAPK enhances collagenase-1 (matrix metalloproteinase (MMP)-1) and stromelysin-1 (MMP-3) expression by mRNA stabilization. J. Biol. Chem. 2002; 277(35)32360–32368
   PubMed Web of Science ®Google Scholar
• Lakka S. S., Jasti S. L., Gondi C., Boyd D., Chandrasekar N., Dinh D. H., Olivero W. C., Gujrati M., Rao J. S. Downregulation of MMP-9 in ERK-mutated stable transfectants inhibits glioma invasion in vitro. Oncogene 2002; 21(36)5601–5608
   PubMed Web of Science ®Google Scholar
• Suyama K., Shapiro I., Guttman M., Hazan R. B. A signaling pathway leading to metastasis is controlled by N-cadherin and the FGF receptor. Cancer Cell 2002; 2(4)301–314
   PubMed Web of Science ®Google Scholar