111
Views
16
CrossRef citations to date
0
Altmetric
ORIGINAL ARTICLEClinical Translational Therapeutics

Serum Vascular Endothelial Growth Factor (VEGF) Levels Correlate with Tumor VEGF and p53 Overexpression in Endocrine Positive Primary Breast Cancer

, , , , , , , , , , , , , , , , & show all
Pages 250-255 | Published online: 11 Jun 2009

REFERENCES

  • Papetti M., Herman I. M. Mechanisms of normal and tumor-derived angiogenesis. Am. J. Physiol. 2002; 282: 947–970
  • Folkman J. What is the evidence that tumors are angiogenesis dependent?. J. Natl. Cancer Inst. 1990; 82: 4–6
  • Ferrara N., Davis-Smyth T. The biology of vascular endothelial growth factor. Endocr. Rev. 1997; 18: 4–25
  • Sanger D. R., Claffey K. P., Benes J. E., Perruzzi C. A., Sergiou A. P., Detmar M. Angiogenesis promoted by vascular endothelial growth factor: Regulation through α1β1 and α2β1 integrins. Proc. Natl. Acad. Sci. U. S. A. 1997; 94: 13612–13617
  • Dvorak H. F., Brown L. F., Detmar M., Dvorak A. M. Vascular permeability factor/vascular endothelial growth factor, microvascular hyperpermeability and angiogenesis. Am. J. Pathol. 1995; 146: 1029–1039
  • Houck K. A., Ferrara N., Winer J., Cachianes G., Li B., Leung D. W. The vascular endothelial growth factor family: Identification of a fourth molecular species and characterization of alternative splicing. Mol. Endocrinol. 1991; 5: 1806–1814
  • Veikkola T., Karkkainen M., Claesson-Welsh L., Alitalo K. Regulation of angiogenesis via vascular endothelial growth factor receptors. Cancer Res. 2000; 60: 202–212
  • Robinson C. J., Stringer S. E. The splice variants of vascular endothelial growth factor (VEGF) and their receptors. J. Cell Sci. 2001; 114: 853–865
  • Neufeld G., Cohen T., Gengrinovitch P., Poltorak Z. Vascular endothelial growth factor (VEGF) and its receptors. FASEB J. 1999; 13: 9–22
  • De Vries C., Escobedo J. A., Ueno H., Houck K., Ferrara N., Williams L. T. The fms-like tyrosine kinase, a receptor for vascular endothelial growth factor. Science 1992; 255: 989–991
  • Terman B. I., Dougher-Vermazen M., Carrion M. E., Dimitrov D., et al. Identification of the KDR tyrosine kinase as a receptor for vascular endothelial cell growth factor. Biochem. Biophys. Res. Commun. 1992; 187: 1579–1586
  • Senger D. R., Perruzzi C. A., Feder J., Dvorak H. F. A highly conserved vascular permeability factor secreted by a variety of human and rodent tumor cell lines. Cancer Res. 1986; 46: 5629–5632
  • Foekens J. A., Peters H. A., Grebenchtchikov N., et al. High tumor levels of vascular endothelial growth factor predict poor response to systemic therapy in advanced breast cancer. Cancer Res. 2001; 61: 5407–5414
  • Fuckar D., Dekanic A., Stifter S., Mustac E., et al. VEGF expression is associated with negative estrogen receptor status in patients with breast cancer. Int. J. Surg. Pathol. 2006; 14: 49–55
  • Yoshiji H., Gomez D. E., Shibuya M., Thorgeirsson U. P. Expression of vascular endothelial growth factor, its receptor, and other angiogenic factors in human breast cancer. Cancer Res. 1996; 56: 2013–2016
  • Anan K., Morisaki T., Katano M., Ikubo A., et al. Vascular endothelial growth factor and platelet-derived growth factor are potential angiogenic and metastatic factors in human breast cancer. Surgery 1996; 119: 333–339
  • Brown L. F., Berse B., Jackman R. W., Tognazzi K., et al. J. Expression of vascular permeability factor (vascular endothelial growth factor) and its receptors in breast cancer. Hum. Pathol. 1995; 26: 86–91
  • Lee A. H. S., Dublin E. A., Bobrow L. G., Poulsom R. Invasive lobular and invasive ductal carcinoma of the breast show distinct patterns of vascular endothelial growth factor expression and angiogenesis. J. Pathol. 1998; 185: 394–401
  • Anan K., Morisaki T., Katano M., Ikubo A., et al. Preoperative assessment of tumor angiogenesis by vascular endothelial growth factor mRNA expression in homogenate samples of breast carcinoma: fine-needle aspirates vs. resection samples. J. Surg. Oncol. 1997; 66: 257–263
  • Anan K., Morisaki T., Katano M., Ikubo M., et al. Assessment of c-erbB2 and vascular endothelial growth factor mRNA expression in fine-needle aspirates from early breast carcinomas: Pre-operative determination of malignant potential. Eur. J. Surg. Oncol. 1998; 24: 28–33
  • Guidi A. J., Schnitt S. J., Fischer L., Tognazzi K., et al. Vascular permeability factor (vascular endothelial growth factor) expression and angiogenesis in patients with ductal carcinoma in situ of the breast. Cancer 1996; 80: 1945–1953
  • Eppenberger U., Kueng W., Schlaeppi J. M., Roesel J. L., et al. Markers of tumor angiogenesis and proteolysis independently define high- and low-risk subsets of node-negative breast cancer patients. J. Clin. Oncol. 1998; 16: 3129–3136
  • Gasparini G., Toi M., Gion M., Verderio P., et al. Prognostic significance of vascular endothelial growth factor protein in node-negative breast carcinoma. J. Natl. Cancer Inst. 1997; 89: 139–147
  • Linderholm B., Tavelin B., Grankvist K., Henriksson R. Vascular endothelial growth factor is of high prognostic value in node-negative breast carcinoma. J. Clin. Oncol. 1998; 16: 3121–3128
  • Kondo S., Asano M., Matsuo K., Ohmori I., Suzuki H. Vascular endothelial growth factor/vascular permeability factor is detectable in the sera of tumor-bearing mice and cancer patients. Biochim. Biophys. Acta 1994; 1221: 211–214
  • Salven P., Maenpaa H., Orpana A., Alitalo K., Joensuu H. Serum vascular endothelial growth factor is often elevated in disseminated cancer. Clin. Cancer Res. 1996; 3: 647–651
  • Kraft A., Weindel K., Ochs A., Marth C., et al. Vascular endothelial growth factor in the sera and effusions of patients with malignant and nonmalignant disease. Cancer 1996; 85: 178–187
  • Yamamoto Y., Toi M., Kondo S., Matsumoto T., et al. Concentrations of vascular endothelial growth factor in the sera of normal controls and cancer patients. Clin. Cancer Res. 1996; 2: 821–826
  • Salven P., Perhoniemi V., Tykka H., Maenpaa H., Joensuu H. Serum VEGF levels in women with a benign breast tumor or breast cancer. Breast Cancer Res. Treat. 1999; 53: 161–166
  • Heer K., Kumar H., Read J. R., Fox J. N., Monnson J. R., Kerin J. M. Serum Vascular Endothelial Growth Factor in breast cancer: Its relation with cancer type and estrogen receptor status. Clin. Cancer Res. 2001; 7: 3491–3494
  • Hyder S M. Sex steroid regulation of vascular endothelial growth factor in breast cancer. Endocr. Relat. Cancer 1996; 13: 667–687
  • Webb N. J., Bottomley M. J., Watson C. J., Brenchley P. E. C. Vascular endothelial growth factor (VEGF) is released from platelets during blood clotting: Implications for measurement of circulating VEGF levels in clinical disease. Clin. Sci. 1998; 94: 395–404
  • O'Byrne K. J., Dobbs N., Propper D., Smith K., Harris A. L. Vascular endothelial growth factor platelet counts and prognosis in renal cancer. Lancet 1999; 353: 1494–1495
  • Curigliano G., Petit J. Y., Bertolini F., Colleoni M., et al. Systemic effects of surgery: quantitative analysis of circulating basic fibroblast growth factor (bFGF), vascular endothelial growth factor(VEGF) and transforming growth factor beta (TGF-β) in patients with breast cancer who underwent limited or extended surgery. Breast Cancer Res. Treat. 2005; 93: 35–40
  • Fuckar D., Dekanic A., Stifter S., Mustac E., et al. VEGF expression is associated with negative estrogen receptor status in patients with breast cancer
  • Foekens J. A., Peters H. A., Grebenchtchikov N., Look M. P., et al. High tumor levels of vascular endothelial growth factor predict poor response to systemic therapy in advanced breast cancer. Cancer Res. 2001; 61: 5407–5414
  • Rydén L., Jirstrom K., Bendhal P. O., Ferno M., et al. Tumor specific expression of vascular endothelial growth factor receptor 2 but not vascular endothelial growth factor or human epidermal growth factor receptor 2 is associated with impaired response to adjuvant tamoxifen in premenopausal breast cancer. J. Clin. Oncol. 2005; 23: 4695–4704
  • Toi M., Matsumoto T., Bando M. Vascular endothelial growth factor: its prognostic, predictive and therapeutic implications. Lancet Oncol. 2001; 2: 667–673
  • Van Meier E. G., Polverini P. J., Chazin V. R., et al. Release of an inhibitor of angiogenesis upon induction of wild type p53 expression in glioblastoma cells. Nat. Genet. 1994; 8: 171–176
  • Gannon J. V., Greaves R., Iggo R., Lane D. P. Activating mutation in p53 produce a common conformational effect: A monoclonal antibody specific for the mutant form. EMBO J. 1990; 9: 1595–1602
  • Nishimura R., Nagao K., Miyayama H., Matsuda M., et al. Higher plasma vascular endothelial growth factor levels correlate with menopause, overexpression of p53 and recurrence of breast cancer. Breast Cancer 2003; 10: 120–128
  • Berns E.M. J.J., Klijn G. M. J., Look M. P., Grebenchtchikov N, et al. Combined vascular endothelial growth factor and p53 status predicts poor response to tamoxifen therapy in estrogen receptor-positive advanced breast cancer. Clin. Cancer Res. 2003; 9: 1253–1258
  • Liang Y., Wu J., Hyder S. M. p53-dependent inhibition of progestin-induced VEGF expression in human breast cancer cells. J. Steroid Biochem. Mol. Biol. 2005; 93: 173–182

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.